[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr11:46,499,874-48,285,906

Best TWAS P=1.57e-12 · Best GWAS P=1.03e-12 conditioned to 0.00322

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	MADD	0.09	0.03	enet	22	0.04	1.9e-03	-7.1	7.1	1.6e-12	-0.72	0.01	0.93	TRUE
7	NTR	Blood	MADD	0.01	0.01	enet	8	0.01	4.7e-03	5.3	6.8	1.0e-11	-0.40	0.16	0.10	FALSE
4	GTEx	Esophagus Mucosa	MADD	0.27	0.04	enet	18	0.12	4.1e-08	-3.2	5.7	9.8e-09	-0.54	0.15	0.46	FALSE
5	GTEx	Esophagus Muscularis	MADD	0.13	0.07	enet	8	0.11	2.0e-07	-3.3	5.7	1.0e-08	-0.62	0.45	0.40	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	CELF1	0.03	0.01	bslmm	289	0.01	2.9e-02	5.2	5.7	1.4e-08	-0.39	0.16	0.13	FALSE
3	GTEx	Artery Tibial	MADD	0.09	0.00	enet	13	0.02	1.1e-02	-2.8	5.6	1.9e-08	-0.63	0.17	0.64	FALSE
2	GTEx	Artery Aorta	PACSIN3	0.10	0.04	lasso	4	0.03	1.1e-02	4.2	5.6	2.2e-08	-0.27	0.36	0.06	FALSE
10	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MADD	0.16	0.05	blup	64	0.08	2.2e-09	5.0	5.5	4.5e-08	-0.31	0.01	0.99	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	MADD	0.33	0.16	enet	23	0.23	1.9e-29	-3.3	5.4	7.1e-08	-0.46	1.00	0.00	FALSE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	MADD	0.15	0.04	enet	10	0.06	4.5e-07	-3.3	5.3	9.3e-08	-0.36	0.14	0.23	FALSE
6	GTEx	Prostate	PSMC3	0.21	0.10	lasso	6	0.20	7.9e-06	5.0	-5.2	1.6e-07	0.12	0.14	0.13	FALSE