Best TWAS P=1.69e-17 · Best GWAS P=8.77e-18 conditioned to 0.733
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RNF219 | 0.08 | 0.02 | enet | 16 | 0.02 | 7.2e-03 | 3.9 | -5.2 | 2.1e-07 | 0.08 | 0.24 | 0.04 | TRUE |
| 2 | METSIM | Adipose | EDNRB | 0.05 | 0.03 | bslmm | 465 | 0.04 | 3.1e-06 | -7.1 | 7.6 | 2.2e-14 | -0.61 | 0.40 | 0.58 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EDNRB | 0.02 | 0.00 | blup | 60 | 0.00 | 3.1e-02 | -8.6 | 8.5 | 1.7e-17 | -0.90 | 0.00 | 0.74 | TRUE |