[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr14:24,098,631-25,489,283

Best TWAS P=6.43e-12 · Best GWAS P=7.44e-12 conditioned to 0.00538

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	METSIM	Adipose	ADCY4	0.07	0.03	lasso	5	0.03	2.2e-05	6.3	6.9	6.4e-12	0.71	0.08	0.92	TRUE
6	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY4	0.06	0.06	lasso	6	0.09	3.0e-10	6.0	6.7	1.6e-11	0.75	0.08	0.92	FALSE
7	The Cancer Genome Atlas	Lung Adenocarcinoma	ADCY4	0.07	0.09	lasso	3	0.08	4.4e-10	4.7	5.9	3.7e-09	0.73	0.78	0.22	FALSE
10	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R2	0.04	0.04	lasso	1	0.02	2.5e-02	5.8	-5.8	8.3e-09	-0.70	0.04	0.55	FALSE
5	The Cancer Genome Atlas	Colon Adenocarcinoma	ADCY4	0.07	0.02	lasso	4	0.03	4.7e-03	4.6	5.5	4.8e-08	0.70	0.03	0.76	FALSE
4	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ADCY4	0.03	0.01	blup	75	0.03	1.1e-03	4.2	5.4	8.0e-08	0.71	0.05	0.72	FALSE
8	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LTB4R	0.16	0.05	blup	73	0.08	4.9e-04	3.1	-5.3	1.4e-07	-0.70	0.02	0.60	FALSE
2	GTEx	Thyroid	ADCY4	0.13	0.13	lasso	6	0.09	1.0e-07	4.0	5.2	2.0e-07	0.51	0.49	0.51	FALSE
9	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R	0.04	0.01	blup	73	0.01	4.2e-02	5.8	-5.2	2.1e-07	-0.63	0.01	0.45	FALSE
1	GTEx	Heart Atrial Appendage	ADCY4	0.28	0.14	lasso	4	0.10	2.1e-05	6.3	5.1	2.7e-07	0.48	0.08	0.82	FALSE