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Traits
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Leg fat-free mass (left)
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chr1:149,672,809-150,515,021
Best TWAS P=5.86e-10 · Best GWAS P=7.72e-19 conditioned to 1.88e-07
149.7M
149.8M
149.9M
150M
150.1M
150.2M
150.3M
150.4M
150.5M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Breast Invasive Carcinoma
C1orf54
0.06
0.02
enet
13
0.02
1.2e-05
4.7
-6.2
5.9e-10
-0.15
0.00
0.90
TRUE
1
GTEx
Artery Tibial
HIST2H2AA3
0.22
0.02
enet
20
0.12
1.8e-09
8.1
6.2
7.5e-10
0.70
0.00
1.00
TRUE
2
GTEx
Artery Tibial
RP11-196G18.22
0.25
0.05
lasso
5
0.07
1.8e-06
3.1
6.1
1.2e-09
0.78
0.01
0.98
FALSE
3
GTEx
Artery Tibial
RP11-196G18.24
0.31
0.08
enet
26
0.10
6.1e-08
8.1
5.8
6.5e-09
0.72
0.00
0.99
FALSE