TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat-free mass (left)
:
←
→
chr1:180,186,713-181,614,143
Best TWAS P=6.55e-08 · Best GWAS P=2.34e-08 conditioned to 0.136
180.2M
180.4M
180.6M
180.8M
181M
181.2M
181.4M
181.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Thyroid Carcinoma
KIAA1614
0.25
0.08
lasso
3
0.07
3.6e-07
5.6
-5.4
6.5e-08
-0.94
0
1
TRUE
1
CommonMind
Brain Pre-frontal Cortex
KIAA1614
0.19
0.17
lasso
7
0.18
2.9e-21
5.6
-5.4
8.6e-08
-0.97
0
1
FALSE