[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr1:177,195,050-178,753,162

Best TWAS P=1.78e-13 · Best GWAS P=3.38e-52 conditioned to 3.16e-29

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Lung	RASAL2-AS1	0.14	0.01	lasso	7	0.05	1.1e-04	0.76	7.4	1.8e-13	0.49	0.53	0.09	TRUE
13	GTEx	Skin Sun Exposed Lower leg	RASAL2-AS1	0.06	0.00	enet	23	0.02	1.8e-02	-6.43	7.0	3.3e-12	0.24	0.13	0.04	TRUE
10	GTEx	Muscle Skeletal	SEC16B	0.18	0.04	lasso	6	0.05	2.3e-05	6.12	6.8	8.7e-12	0.32	0.47	0.02	TRUE
11	GTEx	Muscle Skeletal	RP4-798P15.3	0.18	0.02	lasso	6	0.04	1.7e-04	6.12	6.8	1.2e-11	0.32	0.28	0.03	FALSE
1	CommonMind	Brain Pre-frontal Cortex	LOC730102	0.18	0.12	lasso	9	0.12	1.4e-14	6.12	-6.7	3.0e-11	-0.31	1.00	0.00	FALSE
14	GTEx	Skin Sun Exposed Lower leg	RP11-568K15.1	0.11	0.05	enet	20	0.04	1.3e-04	6.12	-6.6	4.8e-11	-0.38	0.57	0.11	FALSE
5	GTEx	Breast Mammary Tissue (Male)	RP11-568K15.1	0.15	0.18	lasso	3	0.15	2.1e-04	6.12	-6.1	9.2e-10	-0.28	0.06	0.08	FALSE
7	GTEx	Heart Atrial Appendage	RP11-568K15.1	0.22	0.17	lasso	6	0.18	2.7e-08	6.12	-6.0	1.6e-09	-0.29	0.92	0.01	FALSE
3	GTEx	Artery Tibial	RP11-568K15.1	0.14	0.10	lasso	4	0.10	2.0e-08	6.14	-6.0	2.0e-09	-0.28	0.98	0.00	FALSE
2	GTEx	Adipose Subcutaneous	RP11-568K15.1	0.38	0.21	lasso	9	0.20	1.3e-16	6.12	-5.9	3.5e-09	-0.27	1.00	0.00	FALSE
4	GTEx	Breast Mammary Tissue	RP11-568K15.1	0.20	0.11	lasso	7	0.09	2.0e-05	6.12	-5.9	4.4e-09	-0.27	0.75	0.01	FALSE
9	GTEx	Lung	RP11-568K15.1	0.22	0.06	lasso	5	0.14	6.4e-11	6.12	-5.7	9.8e-09	-0.27	0.99	0.00	FALSE
6	GTEx	Esophagus Muscularis	RP11-568K15.1	0.26	0.17	lasso	7	0.18	5.7e-11	6.14	-5.5	4.5e-08	-0.25	1.00	0.00	FALSE
12	GTEx	Nerve Tibial	SEC16B	0.24	0.12	lasso	5	0.18	1.5e-12	7.03	5.3	1.2e-07	0.23	1.00	0.00	FALSE