TWAS hub - KIAA1614

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1900	0.0400	6.9e-12	0.170	0.139	0.178	0.178	0.179	3.6e-20	1.6e-16	3.3e-21	3.3e-21	2.9e-21
2	GTEx	Nerve Tibial	0.3836	0.0666	1.1e-08	0.155	NA	0.170	NA	0.172	4.2e-11	NA	4.4e-12	NA	3.1e-12
3	METSIM	Adipose	0.0555	0.0264	1.8e-02	0.040	0.009	0.027	0.034	0.032	9.6e-07	1.6e-02	4.7e-05	6.5e-06	1.1e-05
4	TCGA	Breast Invasive Carcinoma	0.0251	0.0131	8.9e-03	0.007	0.010	0.010	NA	0.011	1.2e-02	3.1e-03	3.0e-03	NA	1.7e-03
5	TCGA	Colon Adenocarcinoma	0.0920	0.0430	1.9e-03	0.006	0.038	-0.005	NA	0.007	1.3e-01	2.9e-03	9.6e-01	NA	1.2e-01
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.1144	0.0433	4.6e-06	0.005	0.055	0.043	NA	0.031	7.5e-02	7.5e-07	1.1e-05	NA	1.8e-04
7	TCGA	Brain Lower Grade Glioma	0.1433	0.0491	2.9e-05	0.051	0.057	0.073	NA	0.055	2.0e-06	4.6e-07	9.9e-09	NA	6.4e-07
8	TCGA	Soft Tissue Sarcoma	0.1490	0.0740	1.7e-03	0.038	0.058	0.060	NA	0.046	2.5e-03	2.3e-04	1.8e-04	NA	9.9e-04
9	TCGA	Thyroid Carcinoma	0.2480	0.0720	2.8e-06	0.076	0.040	0.052	NA	0.068	7.0e-08	8.3e-05	8.4e-06	NA	3.6e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Ever used hormone-replacement therapy (HRT)	5.9	7.5	23.1	1.3	-2.6	-1.9	-0.1	4.8	1.6	0.2	4.6	2.9
Mean Putamen Volume	5.6	6.4	10.2	-3.1	1.0	-3.2	-2.6	-1.2	-2.9	-3.1	-1.7	-2.9
Forced vital capacity (FVC), Best measure	5.4	19.9	43.0	-6.4	2.2	-4.7	-3.8	-2.4	-4.1	-4.1	-3.8	-6.6
Ever had hysterectomy (womb removed)	4.4	5.0	13.9	1.8	-1.2	1.2	3.7	2.0	2.6	2.0	1.9	2.5
Pain type(s) experienced in last month: Hip pain	4.4	5.5	13.9	2.0	-0.5	0.5	2.5	3.7	3.1	1.5	2.3	2.7
Forced expiratory volume in 1-second (FEV1), Best measure	4.0	12.7	26.7	-5.2	1.2	-4.4	-3.3	-1.5	-2.9	-3.5	-2.7	-5.1
Sitting height	3.8	27.0	62.7	-7.9	3.5	-3.9	-5.0	-2.5	-5.2	-5.0	-2.9	-7.8
Osteoarthritis (self-reported)	3.8	5.0	9.2	2.1	-3.0	-1.5	2.5	2.3	2.3	-0.1	2.3	2.7
Forced vital capacity (FVC)	3.7	14.2	38.3	-6.1	2.3	-3.5	-2.5	-2.5	-2.7	-3.3	-2.2	-6.2
Alzheimer’s Disease (including proxy)	3.6	5.2	12.3	2.2	-2.2	-0.8	1.2	3.5	2.4	-0.2	3.1	2.7
Medication: Allopurinol	3.4	4.6	10.9	2.4	-1.1	2.4	1.2	1.1	1.4	2.9	3.3	2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.1	3.6	9.9	2.1	0.3	2.0	3.1	1.7	2.2	1.4	1.1	1.9
Trunk fat-free mass	3.0	17.5	48.2	-6.9	2.0	-3.6	-3.9	-2.0	-3.9	-3.8	-1.4	-6.5
Trunk predicted mass	3.0	17.4	47.7	-6.9	1.9	-3.6	-3.9	-1.9	-3.9	-3.8	-1.3	-6.4
Whole body fat-free mass	2.9	16.4	41.5	-6.4	2.1	-3.2	-3.9	-2.3	-4.1	-3.8	-1.2	-6.2
Medication: Amlodipine	2.8	3.9	12.9	-3.6	0.4	-2.2	-0.9	-1.0	-0.4	-1.6	-1.8	-3.2
Whole body water mass	2.8	16.1	40.6	-6.4	2.0	-3.3	-3.8	-2.4	-4.1	-3.8	-1.2	-6.1
Leg fat-free mass (right)	2.7	14.3	32.0	-5.6	2.2	-2.7	-3.8	-2.8	-4.2	-3.7	-0.8	-5.7
Leg predicted mass (right)	2.7	14.2	31.6	-5.5	2.2	-2.6	-3.7	-2.8	-4.2	-3.7	-0.8	-5.6
Basal metabolic rate	2.7	14.7	36.0	-6.0	1.9	-3.0	-3.7	-2.5	-4.1	-3.6	-0.9	-5.8
Other serious medical condition/disability diagnosed by doctor	2.6	3.4	9.2	0.8	-1.8	-1.6	1.4	3.0	2.9	0.8	0.3	2.0
Leg fat-free mass (left)	2.6	13.6	29.2	-5.4	2.1	-2.5	-3.7	-2.8	-4.2	-3.6	-0.8	-5.4
Leg predicted mass (left)	2.6	13.5	29.1	-5.3	2.1	-2.6	-3.7	-2.8	-4.2	-3.7	-0.8	-5.4
Reason for reducing amount of alcohol drunk: Health precaution	2.6	3.1	6.7	-2.0	-0.0	-2.6	-1.8	-1.0	-1.5	-2.3	-1.2	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.4	3.2	4.3	1.8	-1.7	0.2	1.8	2.1	2.0	2.0	1.8	2.0
Had menopause	2.4	3.0	7.9	1.3	-2.6	-0.0	0.4	1.9	1.3	0.4	2.8	2.3
Forced expiratory volume in 1-second (FEV1)	2.3	7.7	21.8	-4.7	1.3	-3.3	-1.5	-1.4	-1.7	-2.6	-1.2	-4.4
Arm fat-free mass (right)	2.3	11.9	30.7	-5.5	1.7	-2.5	-3.3	-2.1	-3.6	-3.2	-0.9	-5.4
Medication: Aspirin	2.3	3.1	7.0	1.0	-1.4	1.1	2.1	2.7	2.1	2.4	0.5	1.2
Blood White Count	2.2	16.1	35.4	6.0	-1.8	4.2	4.6	0.9	3.0	5.2	1.1	5.4
Height	2.2	42.9	110.2	-10.5	3.3	-7.3	-3.9	-2.4	-4.6	-6.9	-4.4	-10.1
Arm predicted mass (right)	2.2	11.3	29.4	-5.4	1.7	-2.6	-3.0	-2.0	-3.4	-3.1	-0.7	-5.3
Medication: Aspirin	2.2	2.9	6.4	1.0	-1.4	0.9	2.1	2.5	2.1	2.4	0.5	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.7	11.0	-2.8	-0.2	-3.3	-3.0	0.0	-1.7	-1.8	-0.9	-2.8
Arm predicted mass (left)	2.2	11.3	30.5	-5.5	1.7	-3.0	-2.9	-1.8	-3.2	-3.3	-0.8	-5.1
Schizophrenia vs Biploar Disorder	2.1	2.8	4.8	1.8	-0.5	0.4	2.2	1.9	2.0	1.9	0.9	2.1
Illnesses of mother	2.1	2.5	10.6	-0.9	1.9	2.3	-0.7	-3.3	-0.9	-0.4	-0.5	-1.0
Birth weight	2.1	4.6	9.2	-3.0	1.7	-2.2	-1.3	-0.4	-1.4	-3.0	-1.9	-2.8
Medication for pain relief, constipation, heartburn	2.1	3.6	7.3	-1.6	0.4	-1.7	-2.4	-2.3	-2.7	-1.6	-1.7	-1.6
Qualifications: NVQ or HND or HNC or equivalent	2.1	2.5	5.6	2.4	0.3	2.2	0.8	0.7	0.8	0.9	2.0	2.3
Arm fat-free mass (left)	2.1	10.8	29.2	-5.4	1.5	-2.7	-3.0	-1.9	-3.3	-3.0	-0.7	-5.0
Lung FVC	2.0	10.3	24.0	-4.9	1.9	-3.9	-2.4	-1.7	-2.0	-3.3	-2.1	-4.7
Stomach or abdominal pain in last month	2.0	2.5	6.7	1.6	-1.2	1.1	1.7	0.9	2.6	1.3	1.6	1.6
Number of live births	2.0	2.9	9.6	0.7	-3.1	-2.2	1.1	1.3	1.4	-1.2	1.3	1.6
Impedance of leg (left)	1.9	9.2	19.8	3.3	-1.2	1.2	4.5	3.1	4.2	3.0	0.0	3.6
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	5.0	1.7	-2.2	0.3	1.7	1.9	2.1	1.3	1.7	2.1
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.1	4.4	1.9	-0.5	2.1	1.0	-0.2	1.1	1.4	1.6	2.1
Schizophrenia (2018)	1.8	3.8	9.9	1.6	-0.1	-0.1	2.2	3.0	1.9	3.1	0.3	2.0
Alzheimer’s Disease (in father)	1.8	1.9	4.8	0.8	-0.8	-1.2	1.6	2.2	1.7	-0.1	1.6	1.2
Impedance of leg (right)	1.8	8.7	17.4	3.3	-1.3	1.1	4.2	3.1	3.9	2.9	0.1	3.7
Happiness	1.8	2.2	7.4	0.8	-0.2	-0.5	0.1	2.7	2.0	2.1	1.0	1.1
Standing height	1.8	17.9	55.5	-7.5	3.0	-4.0	-2.3	-0.9	-2.8	-3.7	-2.0	-7.0
Overall health rating	1.8	3.9	15.0	1.2	-1.3	-1.3	1.8	3.9	2.5	0.4	1.4	1.9
Heel T-Score	1.7	13.6	23.3	-4.7	-0.2	-4.8	-3.8	-1.7	-4.7	-2.5	-2.9	-4.8
Diabetes (father)	1.7	2.1	6.7	2.6	-1.5	0.8	1.3	0.8	0.8	0.5	0.7	2.4
Medication: Omeprazole	1.7	2.1	6.4	1.4	-0.1	0.3	2.5	1.7	1.8	1.3	0.7	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.0	6.9	1.5	-1.3	-1.0	1.1	2.6	1.1	-0.4	-0.2	2.0
Commuting to job workplace: Cycle	1.7	2.0	7.2	-1.4	2.7	0.6	-1.4	-0.7	-1.8	0.7	-0.0	-1.6
Schizophrenia (2014)	1.6	3.5	11.1	1.4	-0.3	-0.4	1.9	3.1	1.5	3.3	0.1	1.6
Serious illness, injury or assault to yourself	1.6	2.0	5.3	0.8	-0.9	-0.2	1.8	1.6	2.3	2.1	0.0	0.9
Exposure to tobacco smoke outside home	1.6	2.1	5.3	1.6	0.1	0.9	2.1	0.5	2.3	1.0	0.9	1.8
Qualifications: College or University degree	1.6	5.0	10.0	-2.5	1.5	-0.7	-2.3	-2.5	-2.5	-1.1	-2.7	-3.2
Long-standing illness, disability or infirmity	1.6	2.5	7.3	1.0	-0.5	-1.4	1.8	2.7	2.2	0.3	1.0	1.7
Ovarian Cancer	1.5	1.9	7.9	0.5	0.2	1.3	2.2	0.6	1.5	2.8	-0.2	0.2
Lupus	1.5	2.3	6.1	-0.6	1.8	2.0	-0.4	-2.5	-1.1	-0.2	-2.0	-1.1
Blood Platelet Count	1.5	17.6	47.6	6.9	-1.7	5.2	4.1	-0.3	2.2	5.4	0.3	5.5
Medication for hormone replacement therapy	1.5	1.7	4.4	0.0	-1.6	-1.4	-1.2	1.9	-0.3	0.7	2.1	0.7
Weight	1.5	7.3	17.0	-4.1	1.4	-1.6	-2.7	-2.3	-3.2	-2.3	-0.2	-4.0
Breastfed as a baby	1.5	1.9	4.8	-1.6	1.4	-0.6	-1.3	-1.1	-0.4	-0.7	-2.2	-1.9
Hair/balding pattern: Pattern 4	1.5	3.7	8.2	-2.5	0.5	-1.6	-2.7	-0.6	-2.4	-1.5	-0.5	-2.9
Gout (self-reported)	1.5	2.0	6.0	1.7	-0.6	1.9	0.2	0.2	0.4	1.7	2.5	1.4
Number of self-reported non-cancer illnesses	1.5	2.6	6.6	0.8	0.0	-0.2	2.0	2.6	2.3	1.4	1.7	1.5
Wears glasses or contact lenses	1.5	1.7	4.7	1.6	-0.7	0.3	1.2	2.2	1.6	1.2	0.7	1.3
Medication: Paracetamol	1.5	2.3	4.6	0.9	0.9	2.1	2.0	1.4	2.1	0.4	1.7	1.3
Financial difficulties in last 2 years	1.4	1.8	2.8	1.4	-1.0	0.1	1.7	1.5	1.5	1.6	1.7	1.0
Peak expiratory flow (PEF)	1.4	3.2	9.9	-3.1	0.2	-2.2	0.2	-0.9	-0.0	-2.2	-0.4	-2.8
Medication: Paracetamol	1.4	2.3	4.9	0.9	0.9	2.0	1.5	1.4	2.0	0.5	2.2	1.4
Number of full sisters	1.4	1.7	7.7	-1.3	-0.4	-1.8	-1.1	0.3	-0.2	-2.8	0.8	-0.4
Impedance of whole body	1.4	7.4	13.0	3.4	-0.9	1.2	3.6	2.9	3.4	2.5	0.6	3.5
Alzheimer’s Disease (in mother)	1.3	1.5	4.8	1.0	-1.1	-0.6	0.1	2.2	1.4	-0.1	1.3	1.5
Hand grip strength (left)	1.3	3.3	7.5	-2.5	1.7	-0.6	-1.1	-2.5	-1.6	-1.7	0.5	-2.7
Number of treatments/medications taken	1.3	2.3	5.8	0.8	0.1	0.5	2.4	2.1	2.1	1.2	1.7	0.6
Taking other prescription medications	1.3	2.0	5.6	0.8	-0.1	-0.7	2.3	2.4	2.0	0.8	0.7	0.7
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	8.9	0.8	0.0	0.9	1.3	-0.5	0.3	0.4	3.0	0.9
Falls in the last year	1.3	1.7	8.7	-1.4	0.5	-2.9	-0.8	1.7	0.3	0.2	-0.6	-0.8
Pulse wave reflection index	1.3	1.5	4.4	-1.5	2.1	0.8	-1.3	-0.8	-1.4	-0.5	-0.6	-1.4
Eye problems/disorders: None of the above	1.3	1.5	6.0	1.3	0.1	2.4	1.0	-0.8	1.0	0.1	1.2	1.1
Alcohol intake frequency.	1.3	2.9	7.8	1.9	0.6	2.7	0.8	0.8	1.1	2.8	-0.0	2.2
Comparative height size at age 10	1.3	7.4	23.1	-4.8	2.0	-1.3	-2.7	-0.1	-2.3	-1.8	-1.8	-4.3
Pain experienced in last month	1.3	2.2	6.4	-0.5	0.5	1.2	-1.5	-2.5	-2.2	-0.1	-1.9	-1.2
Reaction Time	1.2	2.2	4.2	1.7	-2.0	0.1	1.3	0.8	1.8	2.0	-0.4	1.8
Fed-up feelings	1.2	2.3	5.8	1.2	0.6	1.6	1.1	1.1	2.1	2.4	1.4	0.9
Hayfever, allergic rhinitis or eczema	1.2	2.6	8.9	1.3	-0.6	1.7	1.4	1.2	1.9	3.0	1.3	1.0
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.8	8.0	-2.0	0.4	-2.8	-0.6	-0.1	-1.5	-2.6	-0.4	-2.0
Hayfever/allergic rhinitis (self-reported)	1.2	1.7	4.1	-2.0	0.5	-1.7	-1.9	0.2	-0.3	-1.0	-0.7	-1.5
Medication: Lansoprazole	1.2	1.4	4.5	-0.5	-1.3	-2.1	0.9	1.7	0.4	-1.1	1.0	-0.3
Number of children fathered	1.2	1.3	3.2	-1.1	-1.8	-1.8	-0.7	1.0	0.7	-1.3	0.6	-0.8
Pulse rate, automated reading	1.2	3.8	10.8	1.6	-0.5	0.5	3.3	2.1	3.1	-0.1	-0.3	2.4
Medication for cholesterol	1.2	1.9	6.0	0.5	1.2	2.5	1.1	-2.3	0.4	-0.1	-1.6	-0.1
Fractured/broken bones in last 5 years	1.2	1.5	4.0	-1.2	-0.1	-2.0	-0.9	1.9	-0.7	-1.5	-0.4	-0.8
Basal cell carcinoma (self-reported)	1.2	1.4	4.0	1.8	-1.4	0.6	-0.1	-0.4	0.0	-0.3	2.0	1.7
Depressed Affect (Nagel 2018)	1.1	2.4	6.9	1.1	1.3	2.2	1.2	0.7	1.8	2.6	1.2	0.8
Ulcerative Colitis	1.1	1.6	4.4	0.9	-1.3	-0.4	0.8	2.1	1.7	0.7	-0.6	1.7
Lung FEV1/FVC ratio	1.1	5.8	12.9	1.6	-3.2	-1.6	1.7	3.6	2.2	-0.4	2.2	3.2
Hand grip strength (right)	1.1	3.1	8.1	-1.9	1.3	-0.4	-1.6	-2.9	-2.2	-1.8	0.7	-1.8
Medication: Atenolol	1.1	1.3	3.0	-1.3	0.1	-1.2	-1.1	-1.1	-1.5	-0.1	-1.7	-1.2
Father’s age at death	1.1	1.5	3.6	0.5	-1.9	-0.2	0.8	1.9	1.7	0.2	1.4	0.6
Length of working week for main job	1.1	1.2	2.4	-1.5	0.7	-1.2	-1.2	1.6	0.0	0.2	-1.2	-1.0
Birth weight of first child	1.1	2.0	6.1	-2.5	1.0	-1.1	-1.7	-0.1	-0.8	-0.3	-1.2	-2.2
Comparative body size at age 10	1.1	3.0	14.1	1.7	0.9	3.8	-0.9	-2.3	-0.8	0.9	0.2	1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	5.2	-1.7	2.3	-1.3	0.4	-0.2	-1.0	-1.6	-1.9	-1.9
Average weekly beer plus cider intake	1.1	1.7	3.4	-1.5	0.9	-1.0	-1.8	-0.3	-1.3	-1.8	-0.9	-1.3
Breast Cancer	1.0	2.4	5.4	-2.3	-0.8	-1.5	-2.3	-0.4	-1.4	-1.0	0.3	-2.2
Rheumatoid Arthritis	1.0	1.4	3.5	1.6	0.7	1.2	1.1	0.5	1.1	0.5	-1.2	1.9
Blood Eosinophil Count	1.0	8.0	19.6	4.4	-3.6	1.1	1.8	1.4	1.8	2.8	2.6	3.8
Neuroticism	1.0	2.5	6.6	0.7	0.9	2.1	1.5	1.0	2.0	2.6	1.7	0.6
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.5	1.4	0.7	1.1	0.5	1.0	1.1	1.1	-0.5	1.6
Supplements: Zinc	1.0	1.1	5.4	0.7	-0.6	0.6	0.0	2.3	1.2	0.1	0.9	1.0
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	4.3	1.5	-0.7	0.3	1.1	0.9	1.3	2.1	1.7	1.0
Mouth/teeth dental problems	1.0	1.5	4.2	-1.5	0.9	-0.4	-0.6	-1.2	-1.5	-0.1	-1.5	-2.1
Medication: Cholesterol lowering	1.0	1.6	4.0	0.4	-0.5	1.6	1.6	0.6	1.9	2.0	0.3	0.5
Medication: Ventolin 100micrograms inhaler	1.0	1.2	3.0	-0.7	-0.7	-0.9	-1.0	-1.1	-1.7	-1.7	-0.1	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	6.2	-0.7	2.5	0.8	1.5	-0.1	0.6	0.5	-1.0	-0.9
Leg pain on walking	1.0	1.2	4.5	0.8	-0.6	-0.8	0.6	2.1	1.4	0.3	0.9	1.2
Loneliness, isolation	1.0	1.4	6.2	-0.5	2.5	0.9	-0.2	0.3	0.3	1.5	-1.7	-0.4
Friendships satisfaction	1.0	1.2	5.0	1.3	-0.9	0.7	1.1	-0.2	0.5	2.2	1.1	0.6
Eye problems/disorders: Cataract	1.0	1.2	4.6	-1.2	-0.8	-2.1	-0.8	1.3	-1.0	-0.1	-0.0	-1.0
Miserableness	1.0	1.8	5.7	0.7	2.4	1.5	0.7	0.8	1.1	2.1	0.5	0.5
Financial situation satisfaction	1.0	1.2	3.5	-0.3	-0.9	-1.3	1.0	1.9	1.7	0.9	0.3	0.3
Commuting to job workplace: Public transport	1.0	1.2	3.4	-0.1	0.4	0.9	-1.8	-0.8	-1.4	-1.4	-1.3	-0.1
Ever had prostate specific antigen (PSA) test	1.0	1.1	2.5	-1.5	0.2	-1.0	-1.3	-0.4	-1.4	-0.4	-0.5	-1.6
Cholesterol lowering medication	1.0	1.4	7.7	-0.3	-0.5	-2.8	-0.8	1.4	-0.3	-1.3	0.4	0.2
Bipolar Disorder (2018)	0.9	1.4	2.8	-1.5	-0.5	-1.7	-1.4	0.0	-1.1	-1.1	-0.7	-1.4
Body Mass Index (BMI) (2010)	0.9	1.2	4.9	1.1	-0.0	2.2	0.9	-0.0	0.5	1.0	0.9	1.4
Type 2 Diabetes (T2D) (2012)	0.9	1.1	2.7	1.3	-0.2	1.3	0.9	0.5	1.0	1.7	1.2	0.5
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	4.7	0.2	0.4	0.1	0.6	2.2	0.8	-1.1	1.2	0.9
Nervous feelings	0.9	1.7	4.9	-0.7	2.2	0.3	1.7	0.9	1.8	1.0	-1.3	-0.3
Hearing difficulty/problems with background noise	0.9	1.4	3.2	1.5	-0.1	-0.3	1.2	1.7	0.6	0.4	1.4	1.8
Heart attack	0.9	1.2	2.5	0.8	-1.0	1.4	1.0	1.0	1.6	0.5	1.1	1.0
Impedance of arm (left)	0.9	4.0	8.6	2.9	-1.1	1.0	2.5	1.9	2.0	1.7	0.8	2.8
Migraine (self-reported)	0.9	1.1	2.8	-0.5	0.1	-1.5	-1.6	-1.0	-1.7	0.0	0.6	-1.0
Mean time to correctly identify matches	0.9	1.6	3.6	0.8	-1.9	-0.3	0.6	1.5	1.9	1.5	0.4	1.4
Chest pain or discomfort	0.9	1.3	4.8	-0.3	-0.3	-0.9	1.7	1.2	2.2	0.5	-1.2	0.3
Breast cancer (self-reported)	0.9	1.1	5.0	0.2	1.0	1.2	0.5	-0.6	1.1	2.2	0.5	-0.0
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.3	0.8	-1.1	1.5	0.8	0.9	1.5	0.6	1.1	1.0
Neuroticism (2016)	0.8	1.2	3.0	0.8	-1.4	0.7	1.5	0.5	1.3	1.7	0.6	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	5.1	-1.2	-0.7	-2.2	-0.8	-0.7	-1.8	-2.1	-0.1	-1.1
Qualifications: CSEs or equivalent	0.8	1.0	2.1	1.0	1.4	0.9	1.4	-0.3	0.5	-1.0	0.7	1.2
Multivitamins +/- minerals	0.8	1.0	3.5	-1.1	1.1	-0.1	-1.9	0.3	-1.2	0.7	-0.3	-1.1
Allergy	0.8	1.9	4.9	-1.1	0.3	-1.6	-2.0	-0.9	-1.5	-2.2	-0.6	-0.9
Medication: Ramipril	0.8	1.0	3.3	0.9	-1.5	0.1	1.8	0.4	0.2	0.5	1.3	0.6
Impedance of arm (right)	0.8	3.7	7.3	2.3	-1.0	0.5	2.7	2.2	2.3	1.7	0.2	2.5
Hip circumference	0.8	3.5	7.6	-2.6	0.5	-0.5	-2.4	-2.1	-2.6	-0.6	-0.1	-2.8
Hair/balding pattern: Pattern 3	0.8	1.1	3.6	-0.1	1.0	1.5	1.0	-0.7	0.8	1.9	-1.1	-0.2
Arm fat mass (right)	0.8	3.3	7.9	-2.1	0.2	-0.6	-2.3	-2.2	-2.8	-1.5	0.7	-2.1
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.7	-0.4	-1.0	-1.3	-0.5	-0.9	-1.0	-1.6	-0.8	-0.9
Illnesses of father: Heart disease	0.8	1.1	3.5	-1.4	1.4	-1.9	0.1	0.4	0.1	0.9	-0.7	-1.0
Illnesses of siblings: Diabetes	0.8	1.0	2.8	-0.7	0.1	-0.2	-1.7	-0.7	-1.6	-1.1	0.5	-0.8
Qualifications: nursing, teaching	0.8	1.2	4.2	-0.5	1.4	1.0	1.1	-0.2	0.3	1.4	-2.1	-0.3
Back pain experienced in last month	0.8	1.1	5.2	-0.4	-0.4	-1.7	0.0	2.3	1.2	-0.4	0.4	-0.1
Mother’s age at death	0.8	1.0	5.5	0.4	-0.2	1.2	0.1	-0.8	0.4	2.4	-1.2	0.1
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.8	-1.6	1.2	-0.5	-0.2	0.8	-0.1	-1.0	0.2	-1.7
Unable to work because of sickness or disability	0.8	1.0	2.2	0.6	-1.3	-1.0	1.0	1.5	0.8	0.3	-0.8	1.1
Myopia	0.8	1.2	2.5	-1.5	1.4	-0.3	-0.7	-0.0	-1.4	-0.2	-1.2	-1.6
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	5.0	0.5	0.9	2.2	1.1	0.1	0.8	1.3	-0.2	0.6
Heart disease (siblings)	0.8	0.9	2.6	0.4	-1.4	-1.5	0.1	0.2	0.7	-0.9	1.6	0.4
Intelligence (Savage-Jansen 2018)	0.7	2.3	4.7	-1.8	0.9	0.7	-1.9	-2.0	-1.6	-0.0	-1.0	-2.2
Verbal and Numeric Reasoning (VNR)	0.7	1.7	4.9	-0.8	-0.8	1.2	-1.9	-2.2	-1.3	-0.2	0.3	-1.5
Medication: Co-codamol	0.7	0.8	2.8	0.4	-0.9	-1.7	0.2	0.5	0.2	-1.3	1.0	0.7
Maternal smoking around birth	0.7	1.0	2.8	1.6	-0.3	0.1	0.9	1.0	-0.3	1.3	0.4	1.7
Hair/balding pattern: Pattern 2	0.7	0.9	2.3	1.1	-1.5	0.2	0.9	-1.2	0.8	-0.7	0.8	0.9
Had other major operations	0.7	0.8	2.8	0.4	0.2	0.5	1.5	0.0	1.7	-0.3	1.0	0.8
Qualifications: None of the above	0.7	1.4	4.4	1.8	-1.6	-0.3	-0.4	0.2	0.3	0.4	1.4	2.1
Pain all over the body in last month	0.7	0.8	3.8	0.2	-0.1	-0.9	0.2	2.0	1.3	-0.3	0.6	0.5
Worrier / anxious feelings	0.7	1.3	4.6	-0.5	-0.3	0.1	1.3	2.1	2.1	0.7	0.9	0.2
Pulse rate	0.7	1.2	3.1	1.1	-1.8	0.2	1.4	0.1	1.6	0.6	-0.2	1.3
Noisy workplace	0.7	0.9	5.0	0.7	-0.5	-0.6	0.8	0.1	0.2	-1.0	2.2	0.6
Exposure to tobacco smoke at home	0.7	0.7	2.1	0.2	1.4	0.4	1.2	-0.9	0.3	-0.1	-1.4	0.0
Blood clot in the leg (DVT)	0.7	1.0	5.1	0.5	1.0	2.2	0.8	-0.4	0.3	1.1	-0.4	0.4
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	4.3	0.3	0.5	-0.6	-2.1	-0.9	-1.6	-1.4	-0.2	0.1
Wheeze or whistling in the chest in last year	0.7	1.2	2.6	1.6	1.3	1.2	1.3	-1.1	0.3	0.8	-0.2	1.1
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.7	-1.1	1.1	-0.2	-0.0	0.9	1.3	1.1	-0.9	-0.9
Had major operations	0.7	0.8	3.0	-0.7	0.2	0.4	0.2	1.6	1.7	0.1	-0.1	-1.0
Handedness (chirality/laterality): Left-handed	0.7	0.9	3.1	-0.9	0.1	-0.9	-1.3	-0.1	-1.2	-1.8	0.0	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	2.2	-0.3	-0.1	-1.4	-1.5	0.6	-0.9	-0.2	1.2	-0.1
Commuting to job workplace: Walk	0.7	0.7	2.4	0.0	0.2	1.5	1.2	-1.2	0.0	0.6	-0.1	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.1	1.3	-0.5	1.1	0.7	0.2	0.7	-0.7	1.5	0.8
Osteoporosis (self-reported)	0.7	0.9	2.9	1.0	-0.4	1.7	-0.3	0.4	1.2	0.9	1.1	0.5
Smoking status: Current	0.7	1.0	2.7	1.6	-1.5	0.1	-0.3	-1.3	-0.8	-0.1	-0.7	1.2
Arm fat mass (left)	0.7	2.8	7.7	-1.8	0.1	-0.4	-2.1	-2.0	-2.8	-1.1	0.9	-1.9
High cholesterol (Self-reported)	0.7	1.2	5.4	0.2	-2.3	-1.4	-0.2	1.2	0.8	-0.4	0.3	0.8
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	2.2	1.1	-0.4	-0.2	1.2	1.5	0.9	0.7	0.9	1.0
Depression (Nagel 2018)	0.6	0.9	3.2	0.8	-0.3	-0.0	0.3	1.4	0.5	1.8	1.0	0.8
Neuroticism (Nagel 2018)	0.6	1.5	3.8	0.6	0.6	1.3	1.4	0.8	1.8	2.0	1.1	0.5
Worry (Nagel 2018)	0.6	1.3	3.7	-0.3	0.9	-0.2	1.7	1.9	1.7	1.1	-0.1	0.2
Crohns Disease (2017)	0.6	1.2	4.1	0.7	-0.2	2.0	-0.5	-1.3	-0.5	1.9	0.7	0.2
Ulcerative Colitis (UC)	0.6	1.1	2.5	1.2	0.0	0.4	1.1	0.8	1.6	0.9	-0.5	1.6
HDL Cholesterol	0.6	0.9	4.4	-0.9	0.6	-2.1	0.4	0.4	-0.1	-0.8	-0.9	-1.1
LDL Cholesterol	0.6	0.9	2.3	-1.1	-0.4	-0.4	-1.4	-0.6	-1.0	-1.5	-0.9	-0.6
Primary Biliary Cirrhosis	0.6	0.8	2.0	0.9	-0.5	0.8	0.8	0.1	1.2	-1.4	1.0	0.7
Allergy or Eczema	0.6	1.5	4.1	1.0	-1.7	0.6	0.7	0.6	1.2	2.0	1.5	0.6
Chronotype (morning person)	0.6	1.3	2.9	-1.2	1.4	-1.7	-1.1	-1.0	-0.9	-0.6	-1.2	-1.1
Average weekly spirits intake	0.6	0.8	2.8	-0.2	-1.0	0.4	0.7	-1.7	0.1	-0.8	-1.3	-0.4
Vitamin and mineral supplements	0.6	0.8	2.7	0.9	-0.4	0.5	1.6	-0.4	1.2	-0.5	0.6	1.1
Supplements: Glucosamine	0.6	0.8	3.7	0.1	-0.9	-0.4	-0.0	0.3	0.0	-1.5	1.9	-0.0
Alcohol usually taken with meals	0.6	0.9	2.1	-0.1	-1.4	-0.4	0.7	1.3	1.3	0.8	1.2	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.2	1.5	-0.3	0.5	1.4	0.2	1.0	0.5	-0.3	1.0
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	2.3	-1.2	0.2	0.2	0.6	0.7	0.4	1.4	-1.3	-1.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.0	1.2	-1.4	0.5	-0.2	0.1	1.1	0.7	-0.6	1.2
Headache pain in last month	0.6	0.9	3.4	1.2	0.4	1.3	0.7	0.0	0.5	-0.2	1.9	1.1
High blood pressure (siblings)	0.6	0.9	3.3	-0.7	-0.1	-1.8	-0.0	1.0	0.1	-0.6	1.5	-0.7
Worry too long after embarrassment	0.6	0.9	5.4	0.1	-0.8	0.6	0.7	0.5	1.1	2.3	0.3	-0.3
Medication: Ibuprofen	0.6	0.7	2.5	0.8	0.7	0.5	1.1	-0.3	0.7	0.7	-1.6	0.2
Heart disease (mother)	0.6	0.7	1.9	0.8	-0.6	-1.4	-0.1	1.4	-0.5	0.0	0.8	0.7
Hearing aid user	0.6	0.7	3.2	-0.1	0.0	-0.6	-0.4	-0.3	-0.8	-1.3	1.8	-0.2
Illnesses of father: High blood pressure	0.6	0.8	3.3	0.9	0.1	-0.0	1.8	0.5	0.1	1.0	-0.6	1.1
Ever smoked	0.6	1.0	3.6	1.0	-0.5	1.9	0.4	-0.2	1.2	1.0	0.9	0.9
Number of operations (self-reported)	0.6	0.8	3.9	-0.1	-0.8	-0.2	0.8	1.1	2.0	0.2	1.0	0.1
Risk taking	0.6	0.8	3.4	0.6	0.5	0.6	0.6	-1.2	-1.0	1.8	-0.3	-0.0
Bipolar Disorder or Schizophrenia	0.5	1.3	5.1	0.3	-0.3	-1.1	0.9	2.3	0.8	1.8	-0.4	0.7
Prostate Cancer	0.5	0.7	3.2	-0.0	0.4	0.1	-0.0	-1.8	-0.9	-1.3	-0.7	0.2
Bipolar Disorder (2011)	0.5	0.5	3.5	0.1	-1.9	-0.8	0.0	0.0	0.0	0.0	0.0	0.0
Sensitivity / hurt feelings	0.5	0.9	4.0	0.4	1.1	0.6	2.0	-0.7	1.1	0.1	-0.4	0.4
Frequency of depressed mood in last 2 weeks	0.5	0.8	3.3	-0.0	1.2	0.8	-0.0	0.8	0.4	1.8	0.7	-0.2
Hearing difficulty/problems: Yes	0.5	0.7	2.4	0.1	-0.5	-1.5	0.9	1.1	0.8	0.5	0.9	0.4
Systolic blood pressure, automated reading	0.5	1.5	3.0	-1.7	0.7	-1.4	1.1	-0.5	-1.5	-1.4	-1.3	-1.0
Diabetes (mother)	0.5	0.7	3.4	0.5	-0.9	0.2	-0.7	1.8	0.9	0.1	0.2	0.5
Severe depression (siblings)	0.5	0.6	2.4	-0.4	-1.5	-0.7	-0.2	0.0	-0.8	-0.7	-0.1	-0.8
Current tobacco smoking	0.5	0.8	2.2	1.4	-1.5	0.1	-0.5	-1.0	-0.7	-0.2	-0.7	1.0
Average weekly fortified wine intake	0.5	0.6	3.1	0.5	-0.9	-0.2	1.8	-0.5	0.5	-0.1	-0.9	0.1
Past tobacco smoking	0.5	1.0	3.5	-1.1	0.2	-1.9	-0.2	0.2	-1.0	-0.2	-1.3	-1.1
Medication: Simvastatin	0.5	0.7	1.3	0.6	-1.0	-0.5	1.2	1.1	1.0	0.6	-0.2	0.9
Mouth/teeth dental problems: Dentures	0.5	0.8	2.0	0.0	1.1	0.2	0.7	1.4	1.2	-0.2	0.8	1.0
Loud music exposure frequency	0.5	0.6	2.2	0.6	-0.3	0.2	0.1	1.0	-0.5	0.7	1.5	0.7
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	3.0	-0.0	1.0	-0.3	0.6	1.6	1.7	0.7	-0.4	0.8
Health satisfaction	0.5	0.7	3.8	0.3	0.0	0.2	0.3	1.9	0.3	1.1	0.6	0.6
Emphysema/chronic bronchitis	0.5	0.6	2.6	-0.6	-0.4	0.4	1.6	-0.4	1.1	0.7	-0.6	-0.1
Medication: Blood pressure	0.5	0.9	4.1	-1.1	-0.6	-0.7	2.0	0.4	1.0	0.0	-0.7	-0.9
Whole body fat mass	0.5	1.9	5.2	-1.7	0.5	-0.3	-1.3	-1.8	-2.3	-0.9	0.4	-1.8
Suffer from ‘nerves’	0.5	0.8	1.9	0.0	1.3	0.6	1.3	0.4	1.1	1.4	-0.1	-0.0
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.3	0.5	0.2	-0.1	1.5	0.2	0.5	1.1	0.8	0.7
Supplements: Vitamin C	0.5	0.5	1.6	0.1	-1.0	0.3	-1.1	0.0	-1.3	-0.3	-0.9	0.1
Knee pain experienced in last month	0.5	0.7	3.3	-0.2	0.2	-1.8	-0.3	1.1	0.4	0.4	1.2	-0.2
Mineral and other dietary supplements	0.5	0.7	1.7	1.0	-0.5	1.0	0.5	-0.6	0.1	1.3	-0.8	1.1
Medication: Gliclazide	0.5	0.5	1.7	0.6	-0.3	0.9	0.3	0.1	-0.4	1.3	-1.0	0.8
Irritable Bowel Disease (IBD)	0.4	0.9	2.7	1.3	-0.2	1.4	0.4	-0.2	0.7	1.6	0.0	1.1
Major Depression (MDD)	0.4	0.5	2.6	0.7	-0.7	0.2	0.0	-1.6	-0.7	0.0	-0.0	0.4
Fasting Glucose	0.4	0.5	1.0	-1.0	0.3	-1.0	-0.8	-0.1	0.0	-1.0	-0.2	-0.5
HbA1C	0.4	0.4	0.8	0.4	-0.6	0.2	0.5	0.6	0.8	-0.6	0.8	0.9
Smoking Status	0.4	1.0	3.6	0.7	-0.8	0.4	-1.4	-1.9	-1.3	-0.5	0.1	0.4
Relative age of first facial hair	0.4	0.8	2.2	0.3	-0.5	-0.4	1.3	0.8	1.1	1.5	0.8	-0.2
Angina	0.4	0.6	1.2	0.5	-0.5	0.9	1.1	0.9	0.5	1.0	-0.3	0.7
Townsend deprivation index at recruitment	0.4	0.5	2.2	0.3	0.8	-0.6	0.0	0.1	0.4	-1.5	-0.9	0.4
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	2.0	-0.7	1.4	0.1	-0.2	-0.3	-0.5	0.9	0.6	-0.3
High blood pressure	0.4	1.2	3.5	-1.9	-0.2	-0.8	0.4	-0.3	-0.8	1.1	-0.7	-1.8
Body mass index (BMI)	0.4	1.8	4.8	-0.9	0.1	0.4	-1.9	-2.1	-2.2	-0.6	0.8	-1.0
Trunk fat mass	0.4	1.9	4.8	-1.7	0.7	-0.2	-1.2	-1.7	-2.2	-1.0	0.5	-1.8
Number of incorrect matches in round	0.4	0.6	1.4	1.2	0.9	-0.1	0.5	0.9	0.8	0.1	-0.2	1.2
Fluid intelligence score	0.4	0.8	2.8	0.3	-0.8	1.6	-0.5	-1.7	-0.9	0.4	-0.1	-0.5
Illnesses of siblings	0.4	0.5	2.6	0.1	0.8	1.1	0.1	-0.3	0.1	0.5	-1.6	0.1
Neuroticism score	0.4	0.9	2.0	-0.1	1.3	1.1	0.7	0.8	1.4	1.4	0.1	-0.3
Alcohol intake versus 10 years previously	0.4	0.6	1.8	0.6	0.2	1.4	-0.4	1.2	-0.2	-0.0	0.3	1.1
Prospective memory result	0.4	0.5	2.8	0.3	1.1	-0.1	-0.0	0.7	-0.2	1.7	0.0	0.2
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.4	-0.5	1.1	-0.5	1.2	0.9	0.4	0.3	0.6	-0.3
Age at first live birth	0.4	0.7	2.8	-1.0	-0.0	0.2	0.4	-0.4	0.3	0.5	-1.4	-1.7
Shortness of breath walking on level ground	0.4	0.5	2.4	0.7	1.6	0.5	0.4	0.5	-0.6	0.1	-0.2	0.7
Leg fat mass (right)	0.4	1.4	4.0	-1.3	0.4	-0.1	-1.2	-1.6	-2.0	-0.7	0.2	-1.5
Age at last live birth	0.4	0.5	1.7	0.2	-0.8	0.3	1.0	-0.4	0.6	0.9	-1.3	-0.4
Family relationship satisfaction	0.4	0.5	2.5	-0.2	-0.5	-1.6	-0.8	0.4	-0.8	-0.1	0.8	-0.1
Hypertension (Self-reported)	0.4	1.1	3.2	-1.8	-0.4	-1.0	0.3	-0.4	-1.1	0.7	-0.9	-1.6
Ever had bowel cancer screening	0.4	0.5	1.6	-0.8	-0.3	-0.7	0.3	1.0	1.3	0.3	0.1	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.3	-0.2	0.4	-0.1	-0.3	0.9	1.3	-0.6	1.5	0.2
Illnesses of father: None of the above (group 1)	0.4	0.5	1.7	-0.0	-0.3	0.5	-1.3	-0.8	-0.0	-1.2	-0.5	-0.4
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.2	-0.5	0.8	-0.2	0.8	0.6	1.1	0.9	0.5	-0.4
Eye problems/disorders: Glaucoma	0.4	0.5	2.7	-0.7	1.6	-0.1	-0.5	-0.3	-0.3	0.1	-0.5	-0.9
Medication: Blood pressure	0.4	0.8	1.6	-1.1	-1.0	-1.0	-0.3	-0.5	-1.3	0.7	0.1	-1.1
Age started oral contraceptive pill	0.4	0.5	2.1	-0.6	0.5	0.1	-0.1	0.7	0.8	0.9	-1.4	-0.5
Ever depressed for a whole week	0.4	0.5	1.6	0.8	-1.3	-0.7	-0.3	0.5	0.7	-0.5	0.6	0.9
Supplements: Calcium	0.4	0.4	1.6	-0.4	-0.1	0.6	-0.6	1.1	1.3	0.0	-0.4	-0.2
Pack years of smoking	0.4	0.6	2.8	-0.8	0.7	0.4	-0.7	-0.5	-0.9	-0.0	-1.7	-0.6
Leg fat mass (left)	0.4	1.5	3.9	-1.4	0.3	-0.2	-1.1	-1.7	-2.0	-0.9	0.2	-1.5
Age at First Birth	0.3	0.5	2.6	-0.1	1.6	0.3	1.0	-0.7	0.1	0.4	-0.2	-0.3
Coronary Artery Disease (CAD)	0.3	0.4	1.4	0.3	0.3	1.0	0.1	0.1	0.3	1.2	-0.7	-0.4
Triglycerides	0.3	0.6	2.5	-0.0	-1.4	0.3	-0.1	-1.6	-0.0	-0.6	-0.5	0.4
BMI	0.3	1.6	4.4	-0.7	0.3	0.8	-1.9	-1.9	-2.1	-0.4	0.2	-1.2
Systolic Blood Pressure	0.3	1.6	9.6	-0.8	-0.9	-1.2	3.1	-0.3	-0.7	-0.9	-0.7	-0.4
Respiratory disease	0.3	0.8	4.9	0.9	-0.0	0.5	2.2	-0.6	0.6	-0.3	0.3	0.2
Medication: Metformin	0.3	0.4	1.3	0.1	0.2	0.6	-1.1	-0.4	-1.1	0.2	-0.6	-0.4
Pack years adult smoking proportion	0.3	0.4	2.1	-0.4	0.3	0.4	-0.7	-0.3	-0.8	-0.0	-1.5	-0.3
Age when periods started (menarche)	0.3	0.7	2.2	-0.1	-0.6	-0.5	1.3	0.2	1.5	-1.0	-0.6	0.1
Chronic bronchitis/emphysema (father)	0.3	0.4	0.7	-0.7	0.1	0.3	-0.7	-0.9	-0.8	0.3	0.8	-0.5
High blood pressure (mother)	0.3	0.4	1.7	0.2	0.2	-1.3	0.2	1.1	-0.3	-0.2	-0.4	0.2
Waist circumference	0.3	1.2	3.5	-1.9	-0.1	-0.6	-1.4	-0.7	-1.4	-0.5	-0.1	-1.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.5	0.5	0.0	0.3	0.6	-1.2	0.0	1.1	-0.3	0.0
Diabetes (self-reported)	0.3	0.5	1.5	-0.1	0.3	0.4	-1.0	0.5	-0.9	0.5	-1.2	-0.1
Arm fat percentage (right)	0.3	1.1	4.2	-0.5	0.0	0.2	-1.4	-1.6	-2.1	-0.6	0.8	-0.7
Time employed in main current job	0.3	0.4	1.3	-0.5	-1.1	-0.4	0.7	0.3	1.0	-0.0	0.1	-0.6
Depression (self-reported)	0.3	0.4	1.8	-0.1	-0.1	-0.9	1.3	0.6	-0.1	0.2	0.7	-0.4
Lung cancer (father)	0.3	0.3	1.7	0.1	-0.2	0.0	0.1	0.1	0.2	-1.1	1.3	0.4
Tense / ‘highly strung’	0.3	0.6	1.3	0.5	-0.9	-0.9	0.6	1.1	1.1	0.2	0.3	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.9	0.5	0.1	0.3	1.4	-0.3	0.5	0.9	0.7	0.1
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.9	1.0	0.3	-0.0	-0.4	-0.2	-0.0	-0.6	0.9	0.7
Number of full brothers	0.3	0.4	2.2	-0.2	-0.1	-1.5	0.3	0.3	-0.0	-0.7	-0.6	0.1
Pulse wave peak to peak time	0.3	0.3	0.9	-0.3	0.1	-0.8	-0.1	-0.6	0.7	-0.3	-1.0	-0.5
Neck or shoulder pain in last month	0.3	0.5	1.3	0.5	-0.8	-0.9	0.5	0.7	1.1	-0.0	-0.2	0.7
Angina (self-reported)	0.3	0.4	0.9	0.3	-0.2	1.0	1.0	0.5	0.2	0.9	-0.6	0.4
Medication: Seretide 50 evohaler	0.3	0.4	1.4	-0.1	0.1	0.5	-0.4	-0.5	-0.5	-0.7	1.2	-0.7
Smoking status: Previous	0.3	0.4	1.4	-0.4	0.4	1.2	-0.9	-0.4	-0.0	-0.6	0.8	-0.3
Arm fat percentage (left)	0.3	1.2	4.2	-0.0	-0.3	0.5	-1.3	-1.7	-2.1	-0.6	1.1	-0.3
Average weekly red wine intake	0.3	0.5	1.3	0.1	-1.2	-0.1	-0.9	0.8	-0.2	0.4	1.1	0.2
Diabetes diagnosed by doctor	0.3	0.5	1.5	0.2	0.4	0.3	-0.3	1.2	-0.2	1.0	-1.1	0.4
Average weekly champagne plus white wine intake	0.3	0.4	1.0	-0.1	-1.0	-0.6	0.9	0.4	0.5	0.5	-1.0	-0.0
Ever taken oral contraceptive pill	0.3	0.4	2.2	-0.4	0.0	-1.5	-0.4	0.2	0.2	-0.3	-0.5	-0.6
Medication: Bendroflumethiazide	0.3	0.5	1.2	-0.6	1.0	0.4	1.1	-0.7	-0.3	0.8	0.2	-0.7
Medication: Lisinopril	0.3	0.4	1.3	-0.7	-0.2	0.0	-0.0	-0.8	-0.9	-0.4	-0.3	-1.1
Medication: Atorvastatin	0.3	0.3	1.5	-0.3	0.1	1.2	0.2	0.2	0.7	0.9	0.4	-0.1
Irritability	0.3	0.6	1.7	0.1	-1.0	0.3	-1.3	-0.4	-0.4	0.4	1.3	-0.5
Diastolic blood pressure, automated reading	0.3	0.9	4.7	0.6	-0.3	-0.6	2.2	0.8	0.4	-0.2	0.5	1.2
Vascular/heart problems diagnosed by doctor	0.3	0.8	3.2	1.2	0.2	-0.2	-0.9	-0.2	0.4	-1.8	-0.4	1.1
Crohns Disease (2012)	0.2	0.4	1.0	0.2	-1.0	0.8	-0.2	-0.7	-0.5	0.6	-0.1	-0.7
Blood Red Count	0.2	2.2	5.1	0.9	-1.5	-0.9	2.2	1.6	1.4	1.1	2.2	0.7
Waist Hip Ratio (WHR)	0.2	0.9	2.2	-0.5	-1.2	-1.1	1.1	1.5	0.7	0.9	-0.8	-0.1
Hypothyroidism (self reported)	0.2	0.6	2.1	0.2	0.9	-0.1	0.1	1.1	1.4	-0.3	-0.4	0.8
Type 2 Diabetes (T2D) (2018)	0.2	0.5	1.4	0.3	0.5	0.5	-1.2	0.2	-0.7	0.4	-1.2	0.3
Tanning	0.2	1.9	6.2	0.4	1.7	1.7	0.1	-2.5	-0.0	1.3	-1.9	-0.2
Medication: Levothyroxine sodium	0.2	0.3	1.4	0.1	1.2	-0.0	0.2	0.2	0.7	0.7	-0.6	0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.7	-0.2	-0.7	-0.6	0.4	-0.5	-0.1	-1.3	-0.5	-0.9
Asthma	0.2	0.3	1.0	-0.1	0.8	0.3	0.7	-0.4	-0.7	-1.0	-0.2	-0.3
Pulse wave Arterial Stiffness index	0.2	0.2	0.8	-0.2	0.0	0.6	-0.2	0.3	-0.9	0.0	0.6	0.1
Glaucoma (self-reported)	0.2	0.2	0.5	-0.4	0.4	-0.7	-0.4	-0.0	0.1	-0.3	-0.3	-0.7
Mood swings	0.2	0.4	1.7	0.2	0.2	0.3	0.3	-0.3	1.3	-0.0	1.3	-0.3
Asthma (self-reported)	0.2	0.4	1.2	-0.0	0.8	0.3	0.9	-0.4	-0.4	-1.1	0.1	-0.2
Guilty feelings	0.2	0.4	1.3	0.2	-1.1	-0.1	-0.3	-0.3	0.5	-0.3	1.1	-0.3
Alcohol drinker status: Previous	0.2	0.2	0.5	-0.2	0.6	0.3	-0.5	0.2	-0.3	0.6	-0.7	0.1
Cardiovascular Disease	0.1	0.4	2.3	-0.1	-0.3	0.0	1.0	0.1	-0.3	1.5	0.2	-0.2
Trunk fat percentage	0.1	0.6	1.5	0.4	0.1	0.9	0.1	-1.1	-1.2	0.2	1.2	0.1
Relative age voice broke	0.1	0.2	0.7	-0.4	0.3	-0.3	0.8	0.2	0.1	0.4	-0.0	-0.5
Body fat percentage	0.1	0.4	1.2	0.4	-0.1	0.7	0.0	-1.1	-1.0	0.3	0.9	0.2
Leg fat percentage (right)	0.1	0.4	0.6	0.8	-0.7	0.8	0.5	-0.5	-0.4	0.8	0.7	0.7
Alcohol drinker status: Never	0.1	0.1	0.4	0.0	0.3	0.3	-0.3	-0.3	-0.0	0.6	0.6	-0.2
Leg fat percentage (left)	0.1	0.5	0.8	0.9	-0.9	0.7	0.7	-0.5	-0.2	0.7	0.6	0.7
Hair Pigment	0.0	0.9	2.8	-0.2	-0.8	-1.7	-0.2	1.4	-0.4	-1.0	1.1	0.2

Hub : Genes

KIAA1614

Models

Trait associations