[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr2:85,083,503-86,513,102

Best TWAS P=7.48e-10 · Best GWAS P=3.93e-09 conditioned to 0.0383

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta GGCX 0.23 0.22 lasso 6 0.23 5.5e-13 4.6 5.2 2.4e-07 0.74 0.48 0.52 FALSE
2 GTEx Artery Tibial GGCX 0.29 0.22 enet 14 0.24 6.3e-19 4.6 5.6 2.6e-08 0.69 0.58 0.41 FALSE
3 GTEx Brain Cerebellum GGCX 0.54 0.30 lasso 10 0.34 6.0e-11 4.6 5.3 1.3e-07 0.75 0.60 0.39 FALSE
4 GTEx Esophagus Muscularis GGCX 0.14 0.12 lasso 9 0.12 1.1e-07 4.6 5.3 9.6e-08 0.75 0.40 0.60 FALSE
5 GTEx Muscle Skeletal GGCX 0.10 0.04 enet 11 0.02 2.7e-03 4.6 5.5 2.9e-08 0.78 0.09 0.91 FALSE
6 GTEx Nerve Tibial GGCX 0.38 0.30 lasso 7 0.33 6.5e-24 4.6 5.5 4.0e-08 0.72 0.60 0.39 FALSE
7 GTEx Pancreas VAMP5 0.29 0.09 enet 4 0.05 3.2e-03 5.3 -5.8 5.8e-09 -0.66 0.02 0.77 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic GGCX 0.13 0.04 enet 11 0.06 3.9e-04 4.6 5.3 9.1e-08 0.64 0.22 0.42 FALSE
9 GTEx Skin Sun Exposed Lower leg GGCX 0.15 0.11 lasso 3 0.18 7.9e-15 4.6 5.8 9.1e-09 0.69 0.34 0.65 FALSE
10 GTEx Testis GGCX 0.38 0.36 enet 25 0.40 8.6e-19 4.7 5.4 8.4e-08 0.72 0.54 0.46 FALSE
11 GTEx Thyroid GGCX 0.30 0.17 enet 10 0.23 1.4e-17 4.6 5.5 4.7e-08 0.74 0.55 0.44 FALSE
12 YFS Blood VAMP8 0.15 0.15 enet 37 0.18 2.2e-55 4.9 -5.1 3.0e-07 -0.75 0.49 0.51 FALSE
13 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma VAMP8 0.06 0.01 enet 15 0.02 2.1e-02 5.1 5.2 1.8e-07 0.45 0.04 0.30 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma GGCX 0.04 0.02 blup 44 0.02 2.7e-03 5.1 6.2 7.5e-10 0.72 0.08 0.78 TRUE