Best TWAS P=9.01e-08 · Best GWAS P=1.55e-09 conditioned to 0.000101
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | METTL21A | 0.10 | 0.02 | lasso | 4 | 0.02 | 0.016 | -4.3 | 5.2 | 2.6e-07 | 0.32 | 0.23 | 0.05 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | CREB1 | 0.15 | 0.00 | enet | 7 | 0.00 | 0.277 | -4.3 | -5.3 | 9.0e-08 | -0.50 | 0.13 | 0.44 | TRUE |