TWAS hub - CREB1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0710	0.0220	7.4e-06	0.066	0.041	0.050	0.054	0.054	1.8e-08	8.8e-06	8.8e-07	3.5e-07	3.2e-07
2	GTEx	Adipose Visceral Omentum	0.1430	0.0500	1.5e-03	-0.005	NA	0.020	NA	-0.004	9.6e-01	NA	3.1e-02	NA	5.8e-01
3	GTEx	Cells Transformed fibroblasts	0.1470	0.0470	9.0e-05	-0.004	NA	0.001	NA	-0.003	9.9e-01	NA	2.8e-01	NA	7.4e-01
4	TCGA	Bladder Urothelial Carcinoma	0.0330	0.0200	1.9e-03	0.009	0.013	-0.001	NA	0.005	5.3e-02	2.5e-02	4.5e-01	NA	1.1e-01
5	TCGA	Breast Invasive Carcinoma	0.0719	0.0381	1.9e-03	0.009	0.010	0.016	NA	0.015	4.1e-03	2.9e-03	2.3e-04	NA	4.0e-04
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.3348	0.0835	4.5e-06	0.046	0.029	0.034	NA	0.035	6.1e-06	2.7e-04	9.2e-05	NA	7.2e-05
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.1108	0.0511	6.1e-05	0.022	0.018	0.021	NA	0.016	1.3e-03	3.3e-03	1.7e-03	NA	5.9e-03
8	TCGA	Lung Squamous Cell Carcinoma	0.0791	0.0610	3.2e-05	0.024	0.024	0.021	NA	0.034	8.6e-04	9.3e-04	1.8e-03	NA	9.1e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2011)	9.7	9.3	14.1	-3.1	1.4	2.4	3.3	3.5	3.4	2.9	3.8
Bipolar Disorder or Schizophrenia	6.8	16.6	27.9	-4.9	0.9	3.0	5.0	4.2	4.3	3.1	5.3
Smoking status: Current	5.8	9.2	19.9	-4.4	2.7	3.0	4.5	1.4	1.0	1.7	3.6
Schizophrenia (2018)	4.8	9.9	18.4	-4.1	0.2	2.3	4.2	2.9	3.1	1.7	4.3
Schizophrenia (2014)	4.7	10.3	17.7	-3.9	0.1	2.4	4.1	3.0	3.5	2.4	4.2
Current tobacco smoking	4.7	7.7	17.1	-4.1	2.7	2.5	4.1	1.2	0.8	1.4	3.3
Hayfever/allergic rhinitis (self-reported)	4.7	6.2	11.1	3.3	1.4	-2.3	-3.2	-1.9	-2.1	-1.6	-3.3
Loneliness, isolation	4.6	6.3	10.8	-2.7	0.8	1.6	3.3	1.9	2.2	3.2	3.2
Bipolar Disorder (2018)	4.4	7.0	9.4	-2.7	1.2	2.0	2.7	3.0	3.0	2.9	3.1
Major Depression (MDD)	4.3	5.2	8.1	-2.8	2.1	1.3	2.7	1.8	1.8	2.6	2.7
Serious illness, injury or assault to yourself	4.1	5.0	7.6	-1.9	2.8	1.5	2.1	1.9	2.3	2.5	2.6
Illness, injury, bereavement, stress in last 2 years	4.0	4.9	10.3	2.1	0.3	-2.0	-1.9	-2.6	-3.2	-1.5	-2.7
Rheumatoid Arthritis	3.8	5.3	11.6	2.0	-0.6	-2.3	-2.8	-1.5	-1.9	-3.4	-2.7
Waist circumference	3.7	13.6	38.9	3.7	-2.6	-6.2	-4.2	-0.5	-1.4	-4.3	-3.3
Financial difficulties in last 2 years	3.7	4.9	7.8	-2.8	2.5	1.2	2.6	2.3	2.0	1.3	2.6
Arm fat-free mass (left)	3.6	18.2	42.5	4.8	-2.2	-6.5	-5.2	-0.8	-1.5	-5.4	-3.9
Arm predicted mass (right)	3.5	17.8	39.7	4.8	-2.0	-6.3	-5.4	-1.0	-1.6	-5.3	-3.9
Arm fat-free mass (right)	3.3	16.8	38.2	4.8	-1.9	-6.2	-5.2	-0.9	-1.4	-5.1	-3.7
Arm predicted mass (left)	3.3	16.7	39.1	4.8	-2.1	-6.2	-5.2	-0.7	-1.4	-5.0	-3.7
Hand grip strength (left)	3.2	8.3	16.4	4.0	0.6	-3.4	-3.4	-1.1	-1.1	-4.0	-2.9
Comparative body size at age 10	3.2	8.9	27.8	2.5	0.8	-5.3	-3.3	-0.6	-1.2	-4.1	-2.5
BMI	3.1	18.0	45.7	4.9	-2.3	-6.8	-5.1	-0.5	-1.2	-5.2	-3.8
Average weekly spirits intake	3.0	3.7	10.0	1.6	1.3	-3.2	-2.1	-0.1	-0.6	-2.8	-1.7
Hearing difficulty/problems: Yes	3.0	4.5	24.4	1.7	4.9	-1.2	-2.2	-0.5	-0.3	0.3	-1.5
Trunk predicted mass	3.0	17.0	38.6	4.7	-1.4	-6.2	-5.2	-1.4	-1.9	-5.0	-4.0
Seen a psychiatrist for nerves, anxiety, tension or depression	3.0	3.8	6.7	-2.4	1.5	1.8	2.1	1.3	2.1	1.4	2.6
Tinnitus: Yes, now most or all of the time	3.0	3.6	7.0	-2.0	-0.8	1.0	1.8	2.6	2.5	0.8	2.4
Sensitivity / hurt feelings	2.9	5.0	7.1	2.2	2.4	-2.0	-2.3	-1.9	-1.8	-2.5	-2.7
Trunk fat-free mass	2.9	16.7	37.7	4.6	-1.4	-6.1	-5.2	-1.3	-1.8	-4.9	-4.0
Depression (self-reported)	2.9	3.5	5.8	-2.4	1.7	1.3	2.2	1.9	1.8	0.5	2.4
Whole body fat-free mass	2.9	16.7	37.3	4.7	-1.9	-6.1	-5.3	-0.7	-1.4	-5.1	-3.8
Whole body water mass	2.9	16.4	36.7	4.6	-2.0	-6.1	-5.2	-0.6	-1.3	-5.1	-3.7
Basal metabolic rate	2.9	16.1	38.1	4.6	-2.2	-6.2	-5.1	-0.4	-1.1	-5.0	-3.5
Unable to work because of sickness or disability	2.9	3.7	8.0	-1.4	1.7	0.3	1.8	2.5	2.8	1.8	2.1
Pain experienced in last month	2.9	4.9	16.4	0.5	-4.0	-0.3	-1.0	-3.2	-2.6	-1.0	-1.9
Hand grip strength (right)	2.7	7.3	13.7	3.7	-0.4	-3.6	-3.2	-1.1	-0.8	-3.7	-2.4
Average weekly fortified wine intake	2.7	3.1	9.6	2.1	0.6	-3.1	-2.0	-1.2	-0.6	-1.4	-1.7
Weight	2.7	13.4	36.5	4.0	-2.7	-6.0	-4.4	0.4	-0.3	-4.4	-2.8
Birth weight of first child	2.7	4.9	10.2	1.7	-1.5	-0.9	-2.0	-2.9	-3.2	-1.2	-3.1
Ever highly irritable/argumentative for 2 days	2.7	3.2	5.1	-1.8	1.9	-0.2	1.9	1.9	2.2	1.4	2.2
Severe depression (siblings)	2.6	3.0	9.4	-0.4	0.6	-0.2	-0.5	3.0	3.1	1.4	1.6
Leg fat-free mass (left)	2.6	13.6	28.6	4.2	-2.2	-5.3	-4.8	0.1	-0.7	-4.9	-3.2
Leg predicted mass (left)	2.6	13.8	29.1	4.2	-2.3	-5.4	-4.9	0.1	-0.7	-4.9	-3.2
Leg fat-free mass (right)	2.6	13.7	27.0	4.3	-2.5	-5.2	-4.9	0.2	-0.6	-4.8	-3.2
Leg predicted mass (right)	2.6	13.9	27.5	4.3	-2.4	-5.2	-5.0	0.2	-0.7	-4.9	-3.2
Alcohol usually taken with meals	2.5	4.0	11.0	3.3	-1.3	-1.9	-3.3	-0.4	-0.5	0.7	-2.1
Impedance of whole body	2.5	12.7	23.6	-3.9	0.9	4.6	4.5	1.4	2.2	4.9	3.7
Medication: Cholesterol lowering	2.4	3.8	7.1	-1.6	2.7	0.4	1.6	2.5	2.6	0.2	2.1
Heart disease (mother)	2.4	2.9	9.6	2.1	-3.1	-1.1	-1.8	-0.5	-0.9	-1.3	-1.4
Alcohol drinker status: Previous	2.4	2.8	4.2	-1.5	2.0	1.4	1.3	1.5	2.1	1.4	2.0
Impedance of arm (right)	2.3	10.9	18.4	-3.6	0.4	4.3	4.0	2.0	2.4	4.2	3.4
Leg pain on walking	2.3	2.8	5.2	-2.0	2.3	1.1	2.0	0.5	1.1	2.1	1.5
Arm fat mass (left)	2.3	9.4	29.6	3.1	-2.6	-5.4	-3.3	0.9	0.3	-3.6	-2.0
Prospective memory result	2.2	2.7	3.9	-1.8	0.0	1.9	1.8	2.0	1.7	1.1	1.8
Ever depressed for a whole week	2.2	2.7	4.0	-1.8	2.0	1.3	1.4	1.6	1.9	1.2	1.8
Leg fat mass (left)	2.2	8.6	25.9	3.0	-2.2	-5.1	-3.2	1.1	0.5	-3.7	-1.8
Impedance of leg (right)	2.1	10.4	19.5	-3.7	2.2	3.9	4.4	0.5	1.5	4.1	3.3
Townsend deprivation index at recruitment	2.1	3.0	5.6	-2.1	2.4	0.6	2.1	1.8	1.4	0.1	1.9
Hearing difficulty/problems with background noise	2.1	3.4	19.1	1.2	4.4	0.4	-0.9	-1.2	-0.6	1.8	-0.7
Body mass index (BMI)	2.0	8.4	25.5	2.9	-2.2	-5.0	-3.2	0.8	0.1	-3.8	-1.9
Impedance of arm (left)	2.0	9.4	17.8	-3.4	0.4	4.1	3.6	1.5	2.0	4.2	3.1
Arm fat mass (right)	2.0	8.2	25.6	2.8	-2.8	-5.1	-3.0	1.2	0.5	-3.4	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.1	5.1	-2.3	0.6	1.1	2.0	2.0	2.1	0.6	2.2
Verbal and Numeric Reasoning (VNR)	1.9	4.7	8.5	2.2	0.6	-1.1	-2.4	-2.9	-2.9	-1.1	-2.7
Waist Hip Ratio (WHR)	1.9	8.7	13.7	3.5	-0.7	-3.0	-3.3	-2.6	-2.5	-3.2	-3.7
Medication: Atenolol	1.9	2.4	8.7	2.5	-0.3	-3.0	-1.8	-0.1	0.2	-0.3	-0.8
Impedance of leg (left)	1.9	9.0	16.3	-3.4	1.6	3.6	4.0	0.7	1.7	4.0	3.1
Illnesses of mother	1.9	2.4	4.2	-2.0	2.0	1.8	2.0	-0.3	0.5	0.8	1.6
Headache pain in last month	1.9	3.3	13.8	-0.3	3.7	1.3	0.3	1.7	2.1	1.4	1.2
Neck or shoulder pain in last month	1.9	2.7	11.1	0.1	3.3	-0.3	0.6	2.2	1.8	0.9	1.0
Whole body fat mass	1.9	7.9	25.5	2.8	-2.3	-5.0	-3.0	1.2	0.5	-3.3	-1.6
Average weekly beer plus cider intake	1.9	2.7	7.1	-2.4	1.0	2.1	2.7	0.4	0.2	0.5	1.8
Ever unenthusiastic/disinterested for a whole week	1.8	2.2	4.4	-2.1	1.4	1.0	1.2	1.5	1.7	1.0	1.7
Leg fat mass (right)	1.8	7.1	22.8	2.5	-2.1	-4.8	-2.8	1.1	0.5	-3.4	-1.5
Eye problems/disorders: Cataract	1.8	2.1	4.2	1.3	-1.3	-2.1	-1.1	-0.9	-1.5	-1.5	-1.5
Chest pain or discomfort	1.7	2.5	12.1	-0.5	3.5	0.3	1.1	-0.4	0.6	2.1	1.0
HDL Cholesterol	1.6	2.6	4.8	-2.2	0.8	1.5	1.8	2.1	1.3	0.4	1.9
Angina	1.6	2.1	5.2	-0.7	1.7	0.3	1.0	2.3	2.0	-0.5	1.7
Falls in the last year	1.6	2.1	7.1	1.3	1.5	-2.7	-1.7	-0.5	-1.1	-0.8	-1.1
Emphysema/chronic bronchitis	1.6	1.8	3.3	-0.9	1.3	-0.4	0.9	1.7	1.8	1.3	1.6
Medication: Aspirin	1.6	2.1	9.3	0.6	3.0	-1.0	0.0	1.5	1.6	0.6	1.0
Body Mass Index (BMI) (2010)	1.5	2.0	9.4	0.7	-1.3	-3.1	-0.7	-1.0	-0.9	-1.1	-0.9
Trunk fat mass	1.5	6.6	20.8	2.5	-2.3	-4.6	-2.8	1.1	0.6	-2.9	-1.4
Hip circumference	1.5	6.7	23.7	2.4	-2.0	-4.9	-2.8	1.1	0.4	-2.9	-1.3
Breastfed as a baby	1.5	1.8	3.9	1.4	-0.3	-0.2	-2.0	-1.3	-1.9	-0.8	-1.7
Angina (self-reported)	1.5	2.0	5.1	-0.5	1.8	0.1	0.9	2.3	1.9	-0.7	1.6
Back pain experienced in last month	1.5	2.2	6.4	-0.6	2.5	-0.7	0.9	1.7	1.7	1.2	1.4
Medication: Aspirin	1.5	2.0	7.8	0.8	2.8	-1.2	-0.3	1.4	1.7	0.6	0.8
Ever smoked	1.5	2.7	6.4	-1.3	2.1	2.5	1.2	1.3	1.5	1.4	1.4
Diastolic blood pressure, automated reading	1.5	4.6	11.5	3.0	-0.7	-3.4	-3.2	0.3	-0.2	-1.3	-1.9
Ever had hysterectomy (womb removed)	1.4	1.6	3.8	1.8	-0.7	-1.9	-1.8	0.4	-0.0	-0.7	-1.1
Systolic blood pressure, automated reading	1.4	3.9	8.9	3.0	-2.3	-2.5	-2.8	0.6	0.1	-0.3	-1.6
Mouth/teeth dental problems	1.4	2.2	3.6	1.2	-0.5	-1.0	-1.5	-1.9	-1.8	-1.6	-1.7
Exposure to tobacco smoke outside home	1.4	1.9	4.8	-0.6	0.9	0.1	0.3	1.9	2.2	2.0	1.3
Family relationship satisfaction	1.4	1.7	4.8	-2.2	-0.6	1.0	1.4	1.3	1.0	0.8	1.5
Guilty feelings	1.4	2.1	6.3	1.2	-0.6	-2.5	-1.5	-0.2	-0.0	-2.3	-0.8
Prostate Cancer	1.3	1.8	6.5	-1.1	-2.5	0.6	1.7	1.1	0.3	-0.7	1.2
Medication for hormone replacement therapy	1.3	1.4	3.0	0.8	1.7	-0.9	-1.2	-1.7	-1.0	0.4	-1.2
Pack years adult smoking proportion	1.3	2.1	5.2	-1.5	2.3	0.6	1.3	1.7	1.5	0.3	1.3
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.2	15.1	0.2	3.9	-0.4	-0.3	-0.2	0.7	1.3	0.1
Eye problems/disorders: Glaucoma	1.3	1.6	5.0	-1.2	0.6	1.4	1.1	-0.3	1.1	2.2	1.2
Alcohol drinker status: Never	1.3	1.6	2.5	-1.6	0.7	-0.2	1.6	0.8	1.4	1.5	1.5
Leg fat percentage (left)	1.3	4.6	16.9	1.8	-1.7	-4.1	-1.9	1.5	1.0	-2.5	-0.7
Irritability	1.3	2.1	3.8	-1.7	0.6	1.1	1.2	1.2	1.9	1.8	1.6
Bilateral oophorectomy (both ovaries removed)	1.2	1.3	3.4	1.8	-0.6	-1.2	-1.8	0.1	-0.2	-0.4	-1.4
Supplements: Glucosamine	1.2	1.6	7.1	-0.4	-1.0	1.0	0.4	0.8	1.2	2.7	1.0
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	2.8	-1.2	0.8	0.2	1.5	1.4	1.5	1.7	1.3
Medication: Ventolin 100micrograms inhaler	1.2	1.6	6.0	-0.2	2.5	1.3	0.4	1.3	1.3	0.6	0.8
Health satisfaction	1.2	1.5	5.1	0.7	2.3	-1.7	-1.2	-0.4	-0.5	-0.8	-1.2
Medication for pain relief, constipation, heartburn	1.2	2.0	8.7	-1.1	-3.0	2.1	0.5	-0.7	-0.6	0.5	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.1	-1.5	1.5	0.7	1.8	0.1	0.6	1.0	1.3
Illnesses of father: High blood pressure	1.2	1.4	3.5	0.3	1.4	1.2	-0.1	1.1	1.9	1.3	1.1
Intelligence (Savage-Jansen 2018)	1.1	3.5	5.2	1.8	1.5	-1.4	-2.1	-2.2	-2.3	-0.9	-2.3
Fasting Glucose	1.1	1.3	2.5	-1.6	1.2	0.4	1.4	1.2	0.7	0.4	1.3
Nervous feelings	1.1	2.1	3.6	-1.9	0.8	1.2	1.9	0.9	1.3	1.1	1.9
Hair/balding pattern: Pattern 2	1.1	1.4	3.1	-1.0	-1.0	1.6	1.8	0.9	0.9	0.7	1.2
Worrier / anxious feelings	1.1	2.0	7.9	-1.3	2.8	0.2	1.3	1.1	1.4	0.2	1.3
Commuting to job workplace: Car/motor vehicle	1.1	1.3	3.2	1.3	0.0	-1.2	-1.2	1.4	0.7	-1.8	-0.4
Illnesses of siblings: Diabetes	1.1	1.4	4.8	-0.6	0.1	0.0	0.1	2.2	2.1	0.7	1.1
Arm fat percentage (left)	1.1	4.4	14.8	1.7	-2.1	-3.9	-2.0	1.6	1.1	-2.2	-0.8
Ever had bowel cancer screening	1.1	1.3	3.2	1.4	1.8	-0.5	-1.0	-1.1	-1.2	-0.4	-1.1
Number of self-reported non-cancer illnesses	1.1	1.9	4.3	1.7	1.3	-2.1	-1.9	-0.8	-0.5	0.1	-1.5
Miserableness	1.1	2.0	8.2	-1.1	2.9	-0.6	0.8	0.4	1.0	1.6	1.3
Hearing aid user	1.1	1.3	3.6	1.4	0.4	-1.9	-1.3	-0.6	-0.6	-0.7	-1.2
Medication: Blood pressure	1.1	2.1	4.6	2.2	-1.3	-1.8	-2.1	-0.6	-1.0	-0.2	-1.3
Pain type(s) experienced in last month: Hip pain	1.1	1.4	7.0	-1.0	2.6	0.3	0.6	-0.1	0.3	1.5	0.3
Medication: Atorvastatin	1.1	1.4	3.4	1.1	0.1	-0.8	-0.7	-1.3	-1.6	-1.8	-1.2
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.0	1.1	0.9	-1.4	-1.7	0.4	-0.3	-0.9	-0.9
Stomach or abdominal pain in last month	1.0	1.2	2.0	-1.4	0.9	1.4	1.4	-0.4	-0.5	1.3	0.8
Arm fat percentage (right)	1.0	4.0	13.6	1.3	-2.1	-3.7	-1.6	1.9	1.3	-2.0	-0.4
Medication: Lansoprazole	1.0	1.2	3.0	-1.7	0.4	-0.3	1.4	0.8	0.8	0.7	1.5
Qualifications: O levels/GCSEs or equivalent	1.0	1.7	3.1	1.3	-1.3	-1.3	-1.4	-1.0	-1.2	-0.9	-1.8
Medication: Paracetamol	1.0	1.6	6.2	1.2	2.5	-1.6	-1.2	-0.3	-0.1	-0.2	-1.0
Medication: Amlodipine	1.0	1.5	3.5	1.1	0.6	-1.9	-1.3	-1.0	-1.0	-1.0	-1.3
Body fat percentage	1.0	3.9	13.5	1.5	-2.3	-3.7	-1.6	1.6	1.1	-2.0	-0.5
Medication: Seretide 50 evohaler	1.0	1.2	3.6	-0.3	0.5	0.0	0.8	1.9	1.8	0.2	1.2
Overall health rating	1.0	2.1	11.1	0.2	3.3	-1.9	-0.2	0.5	0.8	1.0	0.1
Osteoporosis (self-reported)	1.0	1.3	3.7	1.1	0.7	-1.0	-1.6	-0.1	-0.4	-1.9	-0.9
Medication: Paracetamol	1.0	1.6	6.2	1.1	2.5	-1.7	-1.3	0.2	0.1	0.0	-0.8
Myopia	1.0	1.4	2.8	1.5	0.0	-0.6	-1.1	-0.9	-1.5	-1.7	-1.3
Pack years of smoking	1.0	1.4	4.3	-1.1	2.1	0.3	1.0	1.6	1.2	-0.1	1.0
Worry (Nagel 2018)	0.9	1.8	3.5	-1.9	1.1	1.5	1.8	0.9	0.9	0.4	1.7
Neuroticism (2016)	0.9	1.2	7.0	-0.4	2.6	-0.9	0.3	-1.1	-0.9	0.2	-0.2
Triglycerides	0.9	1.6	3.1	1.8	-0.3	-0.6	-1.5	-1.6	-1.3	-0.2	-1.6
Type 2 Diabetes (T2D) (2012)	0.9	1.1	5.9	0.3	2.4	-1.4	-0.4	-0.3	-0.1	-0.6	-0.6
Frequency of depressed mood in last 2 weeks	0.9	1.2	5.0	-0.9	2.2	0.4	1.0	0.7	0.8	0.9	0.8
Pain all over the body in last month	0.9	0.9	3.9	0.9	0.7	-2.0	-1.0	0.5	0.3	-0.8	-0.4
Medication: Simvastatin	0.9	1.4	3.8	-0.4	1.3	0.2	0.5	2.0	1.9	0.2	1.1
Illnesses of siblings	0.9	1.3	4.6	-1.6	-0.6	2.1	1.5	0.0	-0.2	-0.2	0.8
Noisy workplace	0.9	1.1	3.3	-0.0	1.8	0.5	0.4	1.4	1.3	1.0	0.8
Length of working week for main job	0.9	1.0	2.7	1.6	-0.2	-0.6	-1.2	1.0	0.9	-1.0	-0.6
Leg fat percentage (right)	0.9	3.3	13.5	1.3	-1.2	-3.7	-1.3	1.5	1.0	-2.2	-0.4
Supplements: Vitamin C	0.9	1.0	3.2	-0.8	-1.8	0.8	0.9	-0.7	0.1	1.5	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	3.2	1.8	-1.5	-1.4	-1.7	0.1	0.2	-1.7	-1.4
Medication for cholesterol	0.9	1.3	3.4	-1.8	0.9	1.3	1.6	0.6	0.8	0.2	1.1
Number of operations (self-reported)	0.9	1.4	3.3	1.8	-1.5	0.6	-1.4	-0.8	-0.9	0.1	-1.4
Blood Eosinophil Count	0.8	6.0	14.1	1.7	3.8	-2.9	-2.7	-1.3	-1.4	-2.6	-2.0
Smoking Status	0.8	2.0	5.6	-1.6	2.4	1.5	1.5	0.9	0.5	-0.6	1.5
Chronotype (morning person)	0.8	1.8	3.8	-1.5	1.9	1.9	1.3	0.5	0.5	0.7	1.5
Number of treatments/medications taken	0.8	1.4	3.6	-0.2	1.8	0.4	0.5	0.9	1.6	1.9	0.8
Medication: Co-codamol	0.8	1.0	4.8	-0.6	2.2	1.0	0.6	0.2	0.5	0.8	0.6
Trunk fat percentage	0.8	3.2	10.4	1.4	-2.3	-3.2	-1.5	1.4	1.0	-1.7	-0.5
Qualifications: CSEs or equivalent	0.8	1.0	3.2	-0.1	-1.6	-0.3	0.1	0.7	1.8	1.2	0.6
Had other major operations	0.8	1.0	5.6	0.1	-2.4	-0.2	0.0	-0.7	-0.8	1.0	-0.5
Heart attack	0.8	1.0	2.9	0.4	1.2	-1.7	-0.5	1.0	0.5	-1.3	0.0
Birth weight	0.8	1.8	6.0	2.0	-0.1	-1.4	-2.4	0.1	0.1	-0.1	-1.6
Number of full brothers	0.8	1.0	3.2	0.1	-0.2	0.7	0.0	1.8	1.5	1.0	1.0
Alcohol intake frequency.	0.8	1.8	4.9	-0.1	2.2	-0.5	-0.0	1.9	2.1	0.4	1.0
Age at last live birth	0.8	1.2	2.6	-1.0	-1.6	1.6	1.3	0.2	-0.2	-0.5	1.0
Knee pain experienced in last month	0.8	1.2	3.9	-0.4	2.0	-0.2	0.2	1.4	1.4	1.2	0.7
Ever taken oral contraceptive pill	0.8	0.8	2.4	-1.5	0.3	0.8	1.0	0.9	0.9	0.4	0.9
Heart attack/myocardial infarction (self-reported)	0.8	1.0	3.0	0.6	1.0	-1.7	-0.6	0.9	0.3	-1.5	-0.2
Heart disease (siblings)	0.8	0.9	3.2	0.9	-0.5	-1.8	-1.4	0.6	0.9	0.0	-0.4
HbA1C	0.7	0.8	3.8	0.6	0.4	-2.0	-0.8	-0.4	-0.2	-0.7	-0.7
Type 2 Diabetes (T2D) (2018)	0.7	1.3	6.0	1.0	2.4	-1.1	-0.8	0.0	0.5	-0.8	-0.6
Relative age voice broke	0.7	1.0	3.6	0.2	-1.9	1.0	-0.6	-0.8	-0.9	-1.3	-0.6
Fluid intelligence score	0.7	1.4	4.8	0.3	0.8	0.7	-0.6	-2.2	-2.0	0.0	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	3.0	0.6	-1.7	0.1	-1.2	0.5	0.7	-0.9	-0.2
Hair/balding pattern: Pattern 4	0.7	1.8	10.6	-1.2	3.3	0.5	0.5	0.4	0.8	0.3	0.9
High blood pressure (siblings)	0.7	1.0	2.6	1.2	1.5	-1.6	-0.9	0.3	0.7	0.7	-0.2
Shortness of breath walking on level ground	0.7	0.8	1.4	-0.2	1.1	-1.1	0.8	1.0	1.2	-0.5	0.7
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.5	-0.7	0.5	0.0	1.1	1.2	1.1	0.4	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	2.5	0.7	0.7	-0.5	-0.6	-1.1	-1.0	-1.6	-0.9
Number of full sisters	0.7	0.8	1.7	-0.7	1.1	0.2	0.7	1.2	1.3	-0.9	0.9
Mineral and other dietary supplements	0.7	0.9	2.1	0.2	1.5	-1.4	-0.0	-0.9	-1.1	-1.1	-0.3
Age started oral contraceptive pill	0.7	0.9	2.1	0.7	-1.2	-0.4	-1.0	-0.5	-1.4	-0.9	-0.8
Cholesterol lowering medication	0.7	1.0	1.6	1.1	-1.3	-1.0	-0.8	-0.6	-1.1	-1.2	-0.9
Alzheimer’s Disease (in father)	0.6	0.7	1.3	0.5	0.4	-0.9	-0.8	-0.8	-1.1	-0.7	-1.1
Systolic Blood Pressure	0.6	2.8	10.5	3.2	-0.3	-0.8	-2.6	0.9	1.1	1.1	-1.1
Cardiovascular Disease	0.6	2.1	8.5	2.2	-0.8	-2.9	-1.4	0.2	0.3	0.1	-0.8
Vitamin and mineral supplements	0.6	0.8	3.5	-0.8	1.9	-0.5	1.0	0.6	0.3	0.2	0.9
High blood pressure	0.6	1.5	4.0	1.7	-1.5	-2.0	-1.5	-0.3	-0.2	0.5	-0.7
Multivitamins +/- minerals	0.6	0.8	1.9	1.1	-1.0	-0.3	-1.4	-0.1	0.1	-1.2	-0.9
High blood pressure (mother)	0.6	0.9	2.2	1.3	-0.5	-1.5	-1.4	0.4	0.3	-0.5	-0.6
Neuroticism score	0.6	1.3	3.0	-1.5	1.7	0.6	1.4	0.5	0.8	0.5	1.3
Lung cancer (father)	0.6	0.7	1.5	1.1	-1.0	-1.2	-0.6	0.7	0.5	-1.0	-0.1
Exposure to tobacco smoke at home	0.6	0.7	1.9	1.1	-0.5	-0.1	-1.4	-0.1	-0.6	0.0	-1.1
Loud music exposure frequency	0.6	0.7	1.9	1.4	0.6	-0.4	-1.1	-0.6	-0.2	0.7	-0.9
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	4.4	0.4	-2.1	0.2	-0.6	-0.9	-1.1	-0.4	-0.5
Glaucoma (self-reported)	0.6	0.7	2.3	-0.4	-0.6	1.0	0.3	-0.2	1.1	1.5	0.7
Migraine (self-reported)	0.6	0.8	1.5	-1.2	-0.3	1.0	0.9	0.9	0.9	0.3	1.0
Medication: Omeprazole	0.6	0.7	1.9	-1.2	-0.7	0.2	1.4	-0.4	-0.1	0.9	1.0
Hypertension (Self-reported)	0.6	1.7	4.4	1.9	-1.3	-2.1	-1.5	-0.4	-0.4	0.3	-0.9
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.0	1.0	-0.5	-0.3	-0.7	1.4	1.4	0.5	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.0	-0.8	-1.4	0.8	0.8	0.1	-0.0	0.6	0.6
Illnesses of father: None of the above (group 1)	0.6	0.8	2.8	-0.2	-0.4	-0.1	0.2	-1.6	-1.7	0.2	-0.6
Mother’s age at death	0.6	0.7	2.3	0.3	-1.5	-1.5	-0.4	0.0	-0.5	0.7	-0.6
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.9	0.8	-1.7	0.4	-1.1	0.6	0.4	-0.6	-0.7
Risk taking	0.6	0.8	3.9	-0.9	-0.1	1.0	0.8	-0.2	-0.1	2.0	0.5
Alzheimer’s Disease (in mother)	0.5	0.6	2.9	0.3	1.7	1.0	-0.0	0.6	0.5	0.6	0.1
Crohns Disease (2017)	0.5	1.1	3.1	-0.7	0.6	1.5	1.1	0.1	0.7	1.8	1.0
Primary Biliary Cirrhosis	0.5	0.8	1.6	-0.9	0.4	0.2	0.6	1.1	1.3	1.1	1.0
Blood White Count	0.5	4.0	12.1	2.4	-0.2	-3.5	-1.8	-0.8	-1.3	-2.3	-1.8
Hypothyroidism (self reported)	0.5	1.2	5.0	0.8	2.2	-0.9	-1.0	1.1	0.7	-0.3	-0.1
Maternal smoking around birth	0.5	0.8	2.8	-0.1	1.7	-1.0	0.4	0.9	0.6	-0.9	0.3
Fed-up feelings	0.5	0.9	4.8	-0.5	2.2	0.3	0.1	0.3	0.8	1.1	0.5
Taking other prescription medications	0.5	0.8	2.9	-1.1	1.7	0.0	0.8	-0.1	0.3	1.3	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	3.7	1.1	-0.1	-0.9	-1.3	1.9	1.1	-1.0	-0.1
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.1	-0.9	0.4	1.0	0.8	0.7	0.4	0.6	0.8
Past tobacco smoking	0.5	0.9	3.6	0.7	-0.8	-1.9	-0.4	-1.0	-0.8	0.1	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	2.6	-0.2	1.6	-0.2	0.2	1.2	0.9	-0.7	0.7
Forced vital capacity (FVC)	0.5	1.8	3.0	1.7	-0.9	-1.3	-1.0	-1.6	-1.6	-1.2	-1.4
Alcohol intake versus 10 years previously	0.5	0.8	1.7	1.3	-1.3	0.3	-1.1	0.8	0.8	0.1	-0.3
Mouth/teeth dental problems: Dentures	0.5	0.8	2.0	-0.4	1.4	0.8	0.5	1.0	1.1	0.2	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.6	1.3	-0.4	-1.0	-0.8	0.6	0.7	-0.6	-0.6
Standing height	0.5	4.9	10.0	2.9	-1.7	-2.8	-3.2	-0.7	-0.8	-2.2	-2.1
Worry too long after embarrassment	0.5	0.9	2.6	0.6	0.6	0.8	-0.2	-1.1	-1.2	-1.6	-0.7
Number of children fathered	0.5	0.6	1.8	0.0	1.3	-0.1	-0.3	-0.9	-1.2	-0.1	-0.7
Suffer from ‘nerves’	0.5	0.7	1.9	-0.9	1.4	1.0	0.8	0.6	0.5	0.3	1.0
Smoking status: Previous	0.5	0.7	1.8	1.0	-0.4	0.9	-1.3	0.0	0.3	-1.0	-0.9
Mood swings	0.5	0.9	2.5	-1.0	1.6	-0.4	0.7	1.0	1.1	0.6	0.8
Long-standing illness, disability or infirmity	0.5	0.7	3.1	-0.6	1.8	-0.7	0.3	0.1	0.0	1.3	0.1
Friendships satisfaction	0.5	0.6	2.2	0.6	-0.4	-1.5	-1.0	0.2	-0.1	-0.8	-0.7
Qualifications: nursing, teaching	0.5	0.8	3.2	0.3	0.0	-1.8	-0.5	-1.0	-0.9	-0.3	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.1	-0.7	-0.8	-0.7	0.7	0.9	1.1	0.5	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	3.0	1.4	-0.8	-1.7	-0.5	-0.6	-0.5	-1.1	-0.7
Commuting to job workplace: Public transport	0.5	0.5	2.1	-0.4	1.1	-0.2	0.5	-0.3	0.4	1.4	0.5
High cholesterol (Self-reported)	0.5	0.9	2.0	-1.1	-0.1	-0.3	1.4	0.8	1.1	0.9	1.2
Medication: Bendroflumethiazide	0.5	0.7	2.1	1.4	0.2	-0.9	-1.4	0.6	0.6	-0.1	-0.5
Supplements: Calcium	0.5	0.6	1.3	-1.1	0.8	0.0	1.2	0.2	0.2	0.8	0.9
Depressed Affect (Nagel 2018)	0.4	0.9	1.8	-1.0	1.4	-0.5	1.0	0.6	0.7	1.2	1.0
Ovarian Cancer	0.4	0.5	2.9	0.1	1.7	0.7	-0.1	-0.3	-0.1	0.5	0.4
Mean Putamen Volume	0.4	0.4	1.7	-0.7	0.1	-0.3	0.1	-1.3	-1.1	0.0	-0.0
LDL Cholesterol	0.4	0.7	1.7	-1.1	1.2	1.3	0.8	-0.2	-0.2	-0.2	0.6
Lupus	0.4	0.6	3.3	-0.1	-1.8	0.1	-0.1	0.5	0.6	-0.7	0.4
Heel T-Score	0.4	3.0	5.9	2.1	1.1	-2.0	-2.4	-0.2	-0.8	-2.3	-1.5
Lung FVC	0.4	2.1	7.7	0.6	-0.7	-0.7	-0.0	-2.4	-2.8	-1.2	-1.1
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.3	-0.7	0.0	-0.2	0.7	0.8	0.4	1.5	0.6
Medication: Metformin	0.4	0.6	3.3	0.2	1.8	0.2	-0.4	0.2	0.8	0.4	0.2
Diabetes (father)	0.4	0.5	1.2	-0.3	0.4	0.6	0.6	0.9	1.1	0.1	0.9
Age when periods started (menarche)	0.4	1.0	2.3	0.5	1.5	0.5	-0.2	0.9	1.4	1.4	0.8
Medication: Levothyroxine sodium	0.4	0.6	2.7	0.3	1.6	0.3	-0.1	1.1	0.9	-0.2	0.3
Chronic bronchitis/emphysema (father)	0.4	0.5	1.4	-0.4	1.0	-0.7	0.3	1.2	0.6	-0.3	0.3
Number of incorrect matches in round	0.4	0.6	1.3	-0.7	0.5	-0.9	0.6	1.0	1.1	0.2	1.0
Had menopause	0.4	0.5	2.6	-0.5	-1.6	0.3	0.1	0.3	-0.1	1.0	0.2
Diabetes (self-reported)	0.4	0.7	3.7	0.6	1.9	-0.5	-0.8	0.0	0.4	-0.1	-0.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	2.8	1.7	-1.0	-1.3	-0.9	-1.2	-1.0	-0.8	-1.2
Peak expiratory flow (PEF)	0.4	0.9	3.0	1.5	0.5	-1.7	-1.1	-0.2	0.3	-0.0	-0.6
Blood clot in the leg (DVT)	0.4	0.5	2.5	-0.6	-1.6	0.2	0.6	-0.1	-0.6	-0.1	0.2
Wheeze or whistling in the chest in last year	0.4	0.8	3.6	0.5	1.9	-0.7	-0.0	0.6	0.6	1.1	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.2	-0.8	0.9	1.1	0.7	-0.8	-0.1	0.6	0.2
Age at first live birth	0.4	0.8	2.0	-0.3	-1.3	0.1	0.4	-1.0	-1.4	-1.2	0.0
Eye problems/disorders: None of the above	0.4	0.5	1.7	0.0	0.9	1.3	0.2	-0.2	-0.5	-0.9	-0.2
Medication: Allopurinol	0.4	0.5	1.7	0.2	-1.3	-0.2	0.2	-1.0	-1.0	-0.1	-0.6
Mean time to correctly identify matches	0.4	0.8	3.5	-0.0	1.9	-0.8	-0.7	-0.3	0.4	1.2	-0.1
Comparative height size at age 10	0.4	2.3	8.5	1.4	-1.7	-2.9	-1.6	0.0	-0.5	-1.0	-0.9
Diabetes diagnosed by doctor	0.4	0.7	4.1	0.4	2.0	-0.2	-0.8	0.2	0.7	-0.3	-0.3
Medication: Gliclazide	0.4	0.5	1.3	0.2	-1.1	0.2	-0.9	-0.1	-0.3	-1.1	-0.6
Average weekly champagne plus white wine intake	0.4	0.5	2.2	-0.3	-0.4	-1.1	-0.4	-0.4	-0.2	1.5	-0.2
Medication: Lisinopril	0.4	0.5	1.4	0.7	-1.1	-0.3	-1.2	0.1	0.3	0.3	-0.6
Ever had prostate specific antigen (PSA) test	0.4	0.4	1.5	0.2	1.2	-1.0	-0.3	-0.5	-0.6	0.3	-0.2
Fractured/broken bones in last 5 years	0.4	0.5	1.2	0.0	0.2	1.1	0.2	0.5	0.9	1.1	0.6
Depression (Nagel 2018)	0.3	0.4	0.8	-0.7	0.7	0.1	0.9	0.3	0.5	0.9	0.7
Neuroticism (Nagel 2018)	0.3	0.6	3.5	-0.6	1.9	-0.1	0.6	0.3	0.4	-0.1	0.5
Schizophrenia vs Biploar Disorder	0.3	0.4	2.0	0.3	0.3	-0.8	-0.3	0.1	0.1	-1.4	-0.1
Reaction Time	0.3	0.5	1.7	0.1	1.3	-0.7	-0.9	0.2	0.9	0.5	-0.0
Ulcerative Colitis	0.3	0.4	1.1	1.1	0.3	-0.5	-0.7	-0.3	-0.3	-0.5	-0.8
Blood Platelet Count	0.3	3.7	9.2	-0.9	3.0	0.4	1.9	1.3	2.0	2.6	1.9
Height	0.3	5.8	11.6	3.2	-1.6	-3.1	-3.4	1.9	1.5	-2.2	-1.2
Allergy or Eczema	0.3	0.8	2.4	0.8	1.1	0.5	-0.6	1.1	0.7	1.5	-0.1
Neuroticism	0.3	0.7	3.4	-0.8	1.8	0.3	0.8	0.0	0.3	0.5	0.7
Tanning	0.3	4.2	6.7	-1.6	-1.8	2.6	2.1	2.1	1.4	2.4	2.1
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.2	-0.1	-0.4	0.3	0.1	0.6	0.3	1.5	0.0
Diabetes (mother)	0.3	0.4	1.2	0.8	0.0	0.2	-0.6	1.1	0.6	-0.8	-0.2
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.1	0.9	0.5	0.6	-0.7	0.6	0.1	1.4	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	2.0	0.8	0.4	-1.3	-1.0	0.8	0.1	-1.4	-0.3
Qualifications: None of the above	0.3	0.7	1.3	-0.8	-0.2	1.1	1.1	1.0	0.7	-0.5	0.9
Time employed in main current job	0.3	0.3	0.7	-0.5	0.1	0.5	0.9	-0.4	-0.9	-0.7	0.1
Father’s age at death	0.3	0.3	1.2	-1.1	-0.3	0.3	0.6	-0.4	-0.5	0.7	0.0
Pulse rate	0.3	0.5	1.1	-1.0	0.1	0.8	0.8	-0.6	-0.4	1.0	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	2.3	1.5	-1.0	-1.3	-0.9	-0.3	-0.2	-0.9	-0.8
Tense / ‘highly strung’	0.3	0.5	1.9	-1.4	-0.1	0.3	1.0	-0.2	0.2	0.5	1.0
Gout (self-reported)	0.3	0.5	1.1	0.3	-0.8	-0.3	0.1	-1.1	-1.0	-0.3	-0.7
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.7	0.7	1.3	-0.3	-0.8	1.1	0.6	-0.7	-0.2
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.5	0.6	0.4	-1.2	-0.6	0.1	-0.1	-0.4	-0.5
Medication: Ibuprofen	0.3	0.4	0.8	0.7	-0.2	-0.9	-0.5	0.9	0.9	0.0	-0.2
Had major operations	0.3	0.4	1.1	0.2	-0.8	1.1	0.2	-0.4	0.0	1.0	0.3
Illnesses of father: Heart disease	0.3	0.4	1.2	-0.1	0.2	0.1	0.3	0.6	1.1	1.0	0.7
Osteoarthritis (self-reported)	0.3	0.3	1.0	-0.6	0.9	-0.5	0.5	0.1	0.4	1.0	0.2
Commuting to job workplace: Cycle	0.3	0.3	0.8	-0.5	-0.7	0.4	0.5	-0.3	-0.9	-0.6	0.3
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.9	-1.4	0.7	1.7	1.2	-0.4	-0.2	-0.3	0.4
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.0	-0.6	-0.4	-1.0	0.8	-0.7	-0.2	0.3	0.5
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	1.4	-0.4	-1.2	-0.2	0.4	-0.3	-0.8	-0.4	0.0
Irritable Bowel Disease (IBD)	0.2	0.4	1.3	-0.4	-0.2	0.8	0.6	0.1	0.6	1.1	0.4
Breast Cancer	0.2	0.6	2.1	0.2	1.5	-0.7	-0.3	-0.0	1.1	0.5	0.5
Coronary Artery Disease (CAD)	0.2	0.2	1.2	0.4	-0.5	-1.1	0.0	-0.1	0.0	-0.5	-0.1
Respiratory disease	0.2	0.4	1.3	0.5	0.7	0.6	-0.5	-0.1	0.4	1.2	-0.1
Relative age of first facial hair	0.2	0.5	2.1	-0.4	-1.0	1.5	0.3	-0.5	-0.5	-0.3	-0.0
Supplements: Zinc	0.2	0.2	0.7	-0.4	-0.7	0.9	0.5	0.1	-0.3	-0.3	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.8	-0.6	0.9	-0.1	0.3	0.2	0.2	0.8	0.7
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.0	-1.0	-0.3	0.3	0.8	0.1	0.1	0.1	0.1
Allergy	0.2	0.5	1.2	-0.8	-1.1	-0.5	0.8	-0.4	0.1	-0.8	0.5
Hair/balding pattern: Pattern 3	0.2	0.3	0.9	0.4	-1.0	0.1	-0.2	0.0	0.2	0.9	0.2
Number of live births	0.2	0.2	0.6	-0.4	-0.7	0.1	0.4	0.7	0.1	-0.6	0.3
Happiness	0.2	0.2	0.5	-0.5	-0.6	-0.7	0.0	-0.5	-0.1	-0.3	-0.1
Forced vital capacity (FVC), Best measure	0.2	0.6	1.5	1.1	-0.6	-1.2	-0.5	-0.2	-0.2	-1.0	-0.5
Qualifications: College or University degree	0.2	0.7	1.7	1.2	1.3	-0.2	-1.1	0.2	0.6	0.6	-0.3
Pulse rate, automated reading	0.2	0.6	1.4	-1.2	0.0	-0.0	0.6	-1.0	-1.1	-0.9	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.5	0.7	-0.7	-0.5	-0.5	-0.6	-0.4	0.2	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.0	-0.5	0.1	0.6	0.3	0.7	0.4	1.0	0.5
Financial situation satisfaction	0.2	0.3	0.7	-0.5	-0.4	-0.8	0.2	0.5	0.7	-0.6	0.3
Alzheimer’s Disease (including proxy)	0.1	0.1	0.5	0.2	0.7	-0.0	-0.4	0.3	0.2	0.6	-0.3
Ulcerative Colitis (UC)	0.1	0.2	0.8	0.0	-0.9	-0.1	-0.1	0.1	0.3	0.5	-0.2
Age at First Birth	0.1	0.2	0.8	-0.2	-0.9	0.1	0.5	0.1	-0.2	0.0	0.4
Crohns Disease (2012)	0.1	0.2	0.4	0.2	0.6	0.5	-0.0	0.4	0.6	0.4	0.3
Blood Red Count	0.1	0.6	2.4	0.0	0.1	-0.1	0.3	1.3	1.5	0.8	0.6
Lung FEV1/FVC ratio	0.1	0.5	1.5	0.6	-0.8	-0.2	-0.3	0.6	1.0	1.2	0.2
Sitting height	0.1	0.4	1.4	0.3	-0.5	-0.4	-0.8	0.9	0.4	-1.2	-0.2
Medication: Ramipril	0.1	0.1	0.2	-0.2	0.1	0.1	0.3	-0.0	0.2	0.5	0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.4	0.1	1.2	-0.4	-0.3	-0.2	-0.2	0.1	-0.1
Asthma	0.1	0.2	0.5	0.4	0.7	-0.4	-0.4	0.7	0.5	0.1	-0.0
Pulse wave Arterial Stiffness index	0.1	0.1	0.6	0.4	0.8	-0.1	0.1	0.0	-0.4	-0.2	-0.4
Pulse wave peak to peak time	0.1	0.2	1.0	-0.0	-1.0	-0.2	-0.5	-0.1	0.3	-0.0	0.1
Medication: Blood pressure	0.1	0.3	1.0	0.1	1.0	-0.8	0.2	-0.1	0.5	0.3	-0.0
Average weekly red wine intake	0.1	0.2	0.7	0.1	0.3	0.0	-0.8	-0.5	-0.4	0.1	-0.4
Commuting to job workplace: Walk	0.1	0.1	0.4	-0.3	0.3	-0.5	-0.1	-0.2	0.1	0.6	0.2
Breast cancer (self-reported)	0.1	0.2	0.4	-0.3	0.3	-0.5	0.0	0.5	0.6	-0.1	0.3
Asthma (self-reported)	0.1	0.2	0.9	0.0	0.4	-0.2	-0.1	0.9	0.6	0.1	0.3
Wears glasses or contact lenses	0.1	0.1	0.6	0.3	-0.8	0.2	0.1	0.2	-0.1	0.3	0.1
Basal cell carcinoma (self-reported)	0.1	0.1	0.3	0.5	0.4	-0.5	0.0	0.6	0.2	0.0	0.0
Hair Pigment	0.0	0.3	0.7	-0.9	0.7	-0.5	0.7	0.2	-0.0	0.6	0.5
Pulse wave reflection index	0.0	0.0	0.1	0.1	-0.2	0.2	-0.0	-0.2	-0.2	0.0	-0.3

Hub : Genes

CREB1

Models

Trait associations