[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr2:197,745,121-201,516,685

Best TWAS P=1.68e-09 · Best GWAS P=2.83e-11 conditioned to 0.0314

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Whole Blood	PLCL1	0.08	0.08	enet	15	0.05	4.1e-05	-5.6	-6.0	1.7e-09	0.92	0.13	0.87	TRUE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	C2orf60	0.03	0.03	blup	44	0.03	1.8e-04	-5.0	5.3	9.1e-08	-0.05	0.01	0.97	TRUE
4	GTEx	Skin Sun Exposed Lower leg	MARS2	0.04	0.05	enet	8	0.03	1.2e-03	-6.0	5.9	3.6e-09	-0.86	0.15	0.84	FALSE
7	GTEx	Thyroid	RFTN2	0.04	0.01	enet	11	0.01	9.5e-02	-6.0	-5.7	1.2e-08	0.80	0.11	0.67	FALSE
2	GTEx	Adipose Subcutaneous	RFTN2	0.14	0.10	enet	11	0.13	5.3e-11	-5.4	-5.6	1.7e-08	0.86	0.40	0.60	FALSE
3	GTEx	Lung	RFTN2	0.06	0.08	lasso	8	0.06	2.7e-05	-5.8	-5.6	2.2e-08	0.86	0.21	0.78	FALSE
6	GTEx	Spleen	MARS2	0.12	0.04	lasso	5	0.00	3.4e-01	-6.0	5.4	6.2e-08	-0.82	0.08	0.28	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLCL1	0.04	0.00	blup	130	0.02	4.0e-03	1.1	-5.3	8.7e-08	0.65	0.05	0.37	FALSE
5	GTEx	Spleen	RFTN2	0.11	0.03	enet	26	0.05	2.4e-02	-6.1	-5.3	9.1e-08	0.84	0.10	0.28	FALSE
1	CommonMind	Brain Pre-frontal Cortex	TYW5	0.08	0.14	lasso	8	0.13	2.2e-15	-5.0	5.2	2.3e-07	-0.05	0.02	0.98	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	TYW5	0.11	0.12	lasso	5	0.11	5.5e-14	-5.0	5.2	2.4e-07	-0.04	0.02	0.98	FALSE