[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr1:35,908,451-37,494,602

Best TWAS P=7.43e-10 · Best GWAS P=1.52e-10 conditioned to 0.441

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	RP11-268J15.5	0.17	0.14	lasso	2	0.11	2.8e-06	-5.9	-5.6	1.8e-08	0.22	0.04	0.94	FALSE
2	GTEx	Artery Aorta	RP11-268J15.5	0.20	0.14	lasso	4	0.13	1.2e-07	-5.9	-6.2	7.4e-10	0.28	0.04	0.95	TRUE
3	GTEx	Artery Tibial	RP11-268J15.5	0.11	0.10	lasso	3	0.08	4.1e-07	-5.9	-5.5	3.2e-08	0.27	0.05	0.94	FALSE
4	GTEx	Lung	RP11-268J15.5	0.27	0.16	lasso	4	0.15	1.6e-11	-5.9	-5.7	9.7e-09	0.25	0.04	0.96	FALSE
5	GTEx	Lung	SH3D21	0.12	0.02	lasso	1	0.03	2.1e-03	-5.9	5.9	3.4e-09	-0.26	0.04	0.92	FALSE
6	GTEx	Nerve Tibial	RP11-268J15.5	0.18	0.09	lasso	5	0.08	1.5e-06	-5.9	-5.3	1.0e-07	0.23	0.04	0.95	FALSE
7	GTEx	Skin Sun Exposed Lower leg	SH3D21	0.15	0.07	lasso	5	0.08	4.7e-07	5.8	5.9	3.0e-09	-0.36	0.07	0.90	FALSE
8	GTEx	Thyroid	TRAPPC3	0.10	0.08	lasso	3	0.08	7.2e-07	-5.1	5.2	1.5e-07	-0.80	0.26	0.70	FALSE
9	GTEx	Thyroid	RP11-268J15.5	0.13	0.12	lasso	4	0.10	2.7e-08	-5.9	-5.8	8.0e-09	0.26	0.05	0.95	FALSE
10	GTEx	Thyroid	SH3D21	0.14	0.03	lasso	4	0.05	6.6e-05	-5.9	5.2	1.9e-07	-0.24	0.04	0.93	FALSE
11	GTEx	Whole Blood	MAP7D1	0.12	0.09	lasso	3	0.09	8.3e-09	-5.2	-5.3	1.2e-07	0.81	0.68	0.32	TRUE
12	METSIM	Adipose	RP11-268J15.5	0.05	0.06	lasso	3	0.05	4.0e-08	-5.9	-5.5	4.4e-08	0.27	0.04	0.96	FALSE
13	METSIM	Adipose	SH3D21	0.05	0.05	lasso	3	0.04	5.1e-07	-5.9	5.9	4.2e-09	-0.26	0.04	0.96	FALSE
14	NTR	Blood	MAP7D1	0.02	0.03	lasso	3	0.02	3.4e-08	-5.1	-5.2	2.4e-07	0.81	0.25	0.75	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	RP11-268J15.5	0.21	0.16	lasso	5	0.17	4.3e-21	-5.9	-5.4	6.8e-08	0.19	0.02	0.98	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	SH3D21	0.28	0.18	lasso	5	0.19	4.1e-24	-5.9	5.8	4.9e-09	-0.25	0.02	0.98	FALSE
17	YFS	Blood	MAP7D1	0.04	0.03	lasso	7	0.03	8.3e-10	-5.2	-5.3	1.5e-07	0.77	0.69	0.31	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	FAM176B	0.14	0.04	blup	23	0.04	1.8e-03	-5.9	5.2	2.4e-07	-0.33	0.00	0.96	FALSE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	MAP7D1	0.06	0.01	blup	33	0.04	1.3e-03	-5.4	-6.1	1.1e-09	0.77	0.02	0.45	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	TRAPPC3	0.07	0.02	blup	38	0.03	5.7e-03	-4.7	-5.2	1.6e-07	0.64	0.05	0.40	FALSE