[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr1:31,402,148-34,592,020

Best TWAS P=4.89e-18 · Best GWAS P=3.99e-18 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	CommonMind	Brain Pre-frontal Cortex	ZNF362	0.05	0.06	lasso	1	0.06	2.2e-07	-8.7	-8.7	4.9e-18	0.98	0.01	0.99	TRUE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PTP4A2	0.09	-0.01	blup	26	0.00	4.1e-01	5.8	7.0	2.1e-12	0.00	0.01	0.50	TRUE
4	GTEx	Artery Aorta	PEF1	0.15	0.05	lasso	5	0.04	2.2e-03	-5.9	6.6	3.8e-11	-0.05	0.05	0.91	TRUE
20	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	S100PBP	0.06	0.03	blup	48	0.06	6.8e-04	-5.2	6.0	1.5e-09	-0.06	0.01	0.79	TRUE
6	GTEx	Cells EBV-transformed lymphocytes	PHC2	0.58	0.34	lasso	7	0.28	7.3e-10	-8.6	8.3	1.0e-16	-0.99	0.02	0.98	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	PHC2	0.11	0.07	lasso	3	0.05	2.2e-07	-8.6	-8.1	5.6e-16	0.99	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TMEM54	0.05	0.00	blup	281	0.02	4.5e-03	1.8	-7.8	4.5e-15	0.50	0.11	0.23	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZNF362	0.03	0.01	blup	49	0.01	1.3e-03	3.9	-6.5	7.8e-11	0.72	0.01	0.32	FALSE
8	GTEx	Colon Sigmoid	PEF1	0.16	0.09	lasso	3	0.09	4.3e-04	-6.0	6.2	5.0e-10	-0.04	0.05	0.77	FALSE
14	METSIM	Adipose	ZNF362	0.09	0.02	enet	32	0.03	1.5e-05	-8.7	-6.1	1.1e-09	0.70	0.01	0.98	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	KPNA6	0.19	0.14	enet	18	0.10	4.9e-04	5.1	5.8	8.5e-09	-0.03	0.19	0.18	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PEF1	0.04	0.04	lasso	4	0.03	2.8e-04	-5.6	5.6	2.6e-08	-0.01	0.13	0.85	FALSE
17	YFS	Blood	KPNA6	0.03	0.03	bslmm	236	0.04	1.1e-11	5.2	5.5	3.1e-08	0.01	0.73	0.27	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	PEF1	0.04	0.04	lasso	3	0.02	4.2e-04	-5.6	5.4	5.4e-08	-0.01	0.17	0.79	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	S100PBP	0.06	0.06	blup	47	0.05	5.2e-06	-5.4	5.4	5.7e-08	-0.07	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	S100PBP	0.04	0.04	lasso	4	0.04	2.3e-05	-5.4	5.3	8.6e-08	-0.08	0.01	0.99	FALSE
13	METSIM	Adipose	PEF1	0.03	0.02	enet	17	0.02	7.9e-04	-5.6	5.3	1.0e-07	-0.02	0.06	0.85	FALSE
9	GTEx	Muscle Skeletal	ZNF362	0.04	0.01	enet	7	0.02	4.9e-03	3.1	-5.3	1.2e-07	0.68	0.06	0.81	FALSE
12	METSIM	Adipose	KPNA6	0.07	0.06	lasso	10	0.06	1.8e-09	5.0	5.3	1.2e-07	-0.03	0.75	0.25	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	S100PBP	0.03	0.02	blup	46	0.02	6.6e-06	-5.4	5.2	2.3e-07	-0.07	0.01	0.99	FALSE
11	GTEx	Testis	RP4-622L5.7	0.12	0.11	lasso	5	0.08	2.3e-04	5.2	5.2	2.5e-07	-0.03	0.29	0.28	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	EIF3I	0.12	0.06	lasso	1	0.03	7.2e-03	5.1	-5.1	2.8e-07	0.03	0.08	0.06	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	KPNA6	0.02	0.02	blup	29	0.02	1.9e-03	5.1	5.1	2.8e-07	-0.02	0.02	0.86	FALSE
7	GTEx	Cells Transformed fibroblasts	KPNA6	0.13	0.10	lasso	5	0.11	1.3e-08	5.2	5.1	2.9e-07	-0.03	0.68	0.32	FALSE