[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr5:76,597,461-78,753,539

Best TWAS P=1.15e-23 · Best GWAS P=4.37e-22 conditioned to 0.0315

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	AP3B1	0.02	0.00	blup	126	0.01	1.8e-02	-9.7	-10.0	1.2e-23	0.85	0.02	0.90	TRUE
8	The Cancer Genome Atlas	Prostate Adenocarcinoma	AP3B1	0.05	0.02	blup	126	0.03	5.0e-04	7.6	-9.6	1.1e-21	0.81	0.02	0.91	FALSE
2	METSIM	Adipose	AP3B1	0.07	0.01	blup	556	0.02	2.4e-04	4.6	-7.2	4.6e-13	0.54	0.10	0.78	FALSE
5	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	AP3B1	0.16	0.06	enet	18	0.09	2.2e-05	7.2	-7.2	7.2e-13	0.52	0.04	0.51	FALSE
6	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AP3B1	0.08	0.01	enet	20	0.02	9.7e-04	-9.3	-7.1	1.1e-12	0.60	0.02	0.82	FALSE
7	The Cancer Genome Atlas	Lung Adenocarcinoma	AP3B1	0.05	0.03	lasso	3	0.04	4.4e-05	7.2	-6.8	9.0e-12	0.38	0.42	0.26	FALSE
3	YFS	Blood	AP3B1	0.25	0.22	lasso	9	0.23	2.6e-74	6.5	-6.8	1.4e-11	0.30	1.00	0.00	FALSE
9	The Cancer Genome Atlas	Thyroid Carcinoma	AP3B1	0.11	0.06	lasso	2	0.05	1.3e-05	6.5	-6.0	1.6e-09	0.20	0.59	0.05	FALSE
1	GTEx	Testis	LHFPL2	0.18	-0.01	enet	21	0.10	2.1e-05	3.5	5.3	1.4e-07	-0.26	0.11	0.15	FALSE