[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr5:76,597,461-78,753,539

Best TWAS P=1.15e-23 · Best GWAS P=4.37e-22 conditioned to 0.0315

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Testis LHFPL2 0.18 -0.01 enet 21 0.10 2.1e-05 3.5 5.3 1.4e-07 -0.26 0.11 0.15 FALSE
2 METSIM Adipose AP3B1 0.07 0.01 blup 556 0.02 2.4e-04 4.6 -7.2 4.6e-13 0.54 0.10 0.78 FALSE
3 YFS Blood AP3B1 0.25 0.22 lasso 9 0.23 2.6e-74 6.5 -6.8 1.4e-11 0.30 1.00 0.00 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma AP3B1 0.02 0.00 blup 126 0.01 1.8e-02 -9.7 -10.0 1.2e-23 0.85 0.02 0.90 TRUE
5 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma AP3B1 0.16 0.06 enet 18 0.09 2.2e-05 7.2 -7.2 7.2e-13 0.52 0.04 0.51 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma AP3B1 0.08 0.01 enet 20 0.02 9.7e-04 -9.3 -7.1 1.1e-12 0.60 0.02 0.82 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma AP3B1 0.05 0.03 lasso 3 0.04 4.4e-05 7.2 -6.8 9.0e-12 0.38 0.42 0.26 FALSE
8 The Cancer Genome Atlas Prostate Adenocarcinoma AP3B1 0.05 0.02 blup 126 0.03 5.0e-04 7.6 -9.6 1.1e-21 0.81 0.02 0.91 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma AP3B1 0.11 0.06 lasso 2 0.05 1.3e-05 6.5 -6.0 1.6e-09 0.20 0.59 0.05 FALSE