[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr5:111,535,501-112,950,045

Best TWAS P=8.65e-10 · Best GWAS P=9.24e-10 conditioned to 0.006

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	NTR	Blood	REEP5	0.03	0.04	lasso	9	0.04	3.3e-12	5.8	6.1	8.7e-10	-0.66	0.01	0.99	TRUE
8	GTEx	Skin Not Sun Exposed Suprapubic	REEP5	0.11	0.10	lasso	7	0.10	6.3e-06	5.2	5.6	2.1e-08	-0.63	0.09	0.90	FALSE
7	GTEx	Esophagus Mucosa	REEP5	0.19	0.10	lasso	5	0.09	1.5e-06	5.5	5.5	4.5e-08	-0.60	0.03	0.96	FALSE
10	GTEx	Testis	REEP5	0.22	0.14	lasso	5	0.14	6.6e-07	5.1	5.5	4.8e-08	-0.59	0.06	0.93	FALSE
2	GTEx	Adipose Visceral Omentum	REEP5	0.09	0.05	lasso	5	0.02	4.9e-02	5.3	5.4	6.6e-08	-0.60	0.04	0.90	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	REEP5	0.18	0.03	lasso	3	0.03	3.7e-02	5.5	5.4	7.6e-08	-0.61	0.03	0.89	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	APC	0.03	0.02	blup	77	0.02	5.2e-03	5.2	5.3	1.3e-07	-0.45	0.02	0.49	FALSE
5	GTEx	Colon Transverse	REEP5	0.12	0.14	lasso	2	0.14	4.4e-07	5.1	5.2	1.5e-07	-0.58	0.09	0.91	FALSE
1	GTEx	Adipose Subcutaneous	REEP5	0.10	0.09	lasso	2	0.05	2.8e-05	5.2	5.2	1.7e-07	-0.64	0.11	0.88	FALSE
3	GTEx	Artery Aorta	REEP5	0.17	0.07	lasso	13	0.10	4.2e-06	5.8	5.2	1.7e-07	-0.74	0.02	0.98	FALSE
4	GTEx	Artery Tibial	REEP5	0.17	0.12	lasso	5	0.13	3.0e-10	4.7	5.1	3.1e-07	-0.58	0.16	0.83	FALSE
9	GTEx	Skin Sun Exposed Lower leg	CTC-487M23.5	0.17	0.07	lasso	6	0.06	7.7e-06	4.9	5.1	3.1e-07	-0.60	0.23	0.76	FALSE