[Hub]/) : Traits : Leg fat-free mass (left) :

chr5:111,535,501-112,950,045

Best TWAS P=8.65e-10 · Best GWAS P=9.24e-10 conditioned to 0.006

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous REEP5 0.10 0.09 lasso 2 0.05 2.8e-05 5.2 5.2 1.7e-07 -0.64 0.11 0.88 FALSE
2 GTEx Adipose Visceral Omentum REEP5 0.09 0.05 lasso 5 0.02 4.9e-02 5.3 5.4 6.6e-08 -0.60 0.04 0.90 FALSE
3 GTEx Artery Aorta REEP5 0.17 0.07 lasso 13 0.10 4.2e-06 5.8 5.2 1.7e-07 -0.74 0.02 0.98 FALSE
4 GTEx Artery Tibial REEP5 0.17 0.12 lasso 5 0.13 3.0e-10 4.7 5.1 3.1e-07 -0.58 0.16 0.83 FALSE
5 GTEx Colon Transverse REEP5 0.12 0.14 lasso 2 0.14 4.4e-07 5.1 5.2 1.5e-07 -0.58 0.09 0.91 FALSE
6 GTEx Esophagus Gastroesophageal Junction REEP5 0.18 0.03 lasso 3 0.03 3.7e-02 5.5 5.4 7.6e-08 -0.61 0.03 0.89 FALSE
7 GTEx Esophagus Mucosa REEP5 0.19 0.10 lasso 5 0.09 1.5e-06 5.5 5.5 4.5e-08 -0.60 0.03 0.96 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic REEP5 0.11 0.10 lasso 7 0.10 6.3e-06 5.2 5.6 2.1e-08 -0.63 0.09 0.90 FALSE
9 GTEx Skin Sun Exposed Lower leg CTC-487M23.5 0.17 0.07 lasso 6 0.06 7.7e-06 4.9 5.1 3.1e-07 -0.60 0.23 0.76 FALSE
10 GTEx Testis REEP5 0.22 0.14 lasso 5 0.14 6.6e-07 5.1 5.5 4.8e-08 -0.59 0.06 0.93 FALSE
11 NTR Blood REEP5 0.03 0.04 lasso 9 0.04 3.3e-12 5.8 6.1 8.7e-10 -0.66 0.01 0.99 TRUE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma APC 0.03 0.02 blup 77 0.02 5.2e-03 5.2 5.3 1.3e-07 -0.45 0.02 0.49 FALSE