Best TWAS P=3.48e-18 · Best GWAS P=5.69e-20 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 0.00061 | -8.7 | 8.7 | 3.5e-18 | -0.98 | 0.02 | 0.96 | TRUE |
2 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 0.00019 | -5.0 | 6.3 | 2.3e-10 | -0.74 | 0.10 | 0.89 | FALSE |
3 | NTR | Blood | HIVEP2 | 0.02 | 0.01 | blup | 424 | 0.01 | 0.00262 | -3.4 | -5.4 | 6.4e-08 | 0.41 | 0.34 | 0.05 | FALSE |
4 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NMBR | 0.09 | 0.01 | blup | 46 | 0.04 | 0.03380 | 3.6 | -5.3 | 9.0e-08 | 0.11 | 0.02 | 0.64 | TRUE |