TWAS hub - HIVEP2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Heart Left Ventricle	0.3203	0.0800	0.00016	0.02	NA	0.016	NA	0.018	0.03000	NA	0.047	NA	0.0350
2	NTR	Blood	0.0185	0.0085	0.00400	0.01	0.006	0.003	0.006	0.005	0.00023	0.0026	0.023	0.0029	0.0071

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Sitting height	18.5	131.1	259.2	1.8	-16.1
Forced expiratory volume in 1-second (FEV1), predicted	10.6	22.1	34.8	3.1	-5.9
Height	10.0	193.4	361.0	5.1	-19.0
Standing height	9.7	96.1	176.9	3.9	-13.3
Lung FEV1/FVC ratio	8.3	42.1	83.7	-0.7	9.2
Comparative height size at age 10	6.3	34.7	65.0	2.1	-8.1
Forced vital capacity (FVC)	5.3	20.3	38.1	1.6	-6.2
Medication: Atenolol	5.2	6.5	13.0	-3.6	0.3
Forced vital capacity (FVC), Best measure	4.6	16.9	31.4	1.6	-5.6
Basal metabolic rate	4.5	25.0	34.6	3.9	-5.9
Had major operations	4.4	5.2	9.2	1.1	3.0
Leg fat-free mass (left)	4.2	22.5	29.8	3.9	-5.5
Trunk predicted mass	4.2	23.7	32.9	3.8	-5.7
Whole body fat-free mass	4.2	23.9	32.0	4.0	-5.7
Leg predicted mass (left)	4.1	21.9	29.3	3.8	-5.4
Trunk fat-free mass	4.0	23.1	31.9	3.8	-5.7
Hip circumference	4.0	17.2	28.2	2.5	-5.3
Number of children fathered	4.0	4.5	4.7	2.1	2.2
Leg fat-free mass (right)	4.0	21.4	29.6	3.6	-5.4
Whole body water mass	4.0	22.9	30.4	3.9	-5.5
Leg predicted mass (right)	4.0	21.4	29.3	3.7	-5.4
Arm fat-free mass (left)	3.9	20.0	27.4	3.5	-5.2
Medication for hormone replacement therapy	3.8	4.3	6.9	2.6	1.3
Age when periods started (menarche)	3.8	9.1	18.1	4.3	0.3
Arm predicted mass (right)	3.8	19.2	24.9	3.7	-5.0
Arm fat-free mass (right)	3.7	18.8	25.6	3.5	-5.1
Weight	3.6	17.8	27.8	2.8	-5.3
Irritability	3.6	6.1	12.2	-0.3	3.5
Arm predicted mass (left)	3.6	18.4	23.6	3.6	-4.9
Age at last live birth	3.5	5.1	5.9	-2.4	-2.1
Trunk fat mass	3.3	14.0	23.6	2.1	-4.9
Diabetes (father)	3.2	4.0	8.0	0.1	-2.8
Townsend deprivation index at recruitment	3.0	4.1	6.6	1.3	2.6
Exposure to tobacco smoke at home	3.0	3.3	6.1	-0.8	2.5
Mood swings	2.9	5.3	10.1	0.6	3.2
Bipolar Disorder (2011)	2.7	2.6	5.2	0.0	2.3
Frequency of depressed mood in last 2 weeks	2.7	3.8	5.0	-1.6	2.2
Hypothyroidism/myxoedema (self-reported)	2.7	5.3	7.6	2.8	1.8
Number of operations (self-reported)	2.7	4.0	7.9	0.3	2.8
Heart attack	2.6	3.4	6.6	-2.6	-0.4
Prospective memory result	2.6	3.2	6.4	-2.5	0.1
Medication: Paracetamol	2.6	4.3	7.3	1.1	2.7
Birth weight	2.6	5.6	9.6	1.2	-3.1
Seen a psychiatrist for nerves, anxiety, tension or depression	2.6	3.4	6.5	0.5	2.5
Ever taken oral contraceptive pill	2.6	2.9	5.2	2.3	0.7
Commuting to job workplace: Cycle	2.6	3.1	5.9	2.4	-0.6
Knee pain experienced in last month	2.5	3.9	6.4	2.5	1.2
Medication: Paracetamol	2.5	3.8	7.2	0.7	2.7
Heart attack/myocardial infarction (self-reported)	2.5	3.3	6.3	-2.5	-0.5
Depressed Affect (Nagel 2018)	2.4	5.0	9.9	-0.2	3.1
Taking other prescription medications	2.4	3.8	4.8	1.6	2.2
Noisy workplace	2.4	2.9	4.7	1.1	2.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.4	2.9	5.5	-0.5	2.3
Loneliness, isolation	2.4	3.3	5.2	-1.1	2.3
Diabetes (self-reported)	2.3	3.6	7.1	0.1	-2.7
Impedance of arm (left)	2.3	10.5	18.2	-1.7	-4.3
Whole body fat mass	2.3	9.6	15.8	1.9	-4.0
Supplements: Zinc	2.2	2.4	3.5	-1.1	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.2	3.3	6.3	-0.6	2.5
Ever depressed for a whole week	2.2	2.8	3.3	-1.5	1.8
Major Depression (MDD)	2.1	2.6	4.9	0.5	2.2
Tense / ‘highly strung’	2.1	3.5	5.8	-2.4	1.1
Smoking status: Previous	2.1	3.1	5.4	2.3	0.9
Impedance of whole body	2.1	10.9	17.9	-2.0	-4.2
Worry (Nagel 2018)	2.0	4.2	7.5	-2.7	1.0
Neuroticism	2.0	4.9	6.8	-1.8	2.6
Trunk fat percentage	2.0	8.0	14.7	1.1	-3.8
Suffer from ‘nerves’	2.0	3.1	6.2	-2.5	0.1
Commuting to job workplace: Car/motor vehicle	2.0	2.3	3.7	0.9	1.9
Basal cell carcinoma (self-reported)	2.0	2.3	4.0	0.8	-2.0
Hypothyroidism (self reported)	1.9	4.4	7.6	2.8	1.1
Medication: Amlodipine	1.9	2.6	5.2	0.1	-2.3
Wheeze or whistling in the chest in last year	1.9	3.3	3.9	1.6	2.0
Diabetes (mother)	1.8	2.3	4.7	0.1	-2.2
Impedance of arm (right)	1.8	8.5	13.7	-1.8	-3.7
Medication: Blood pressure	1.8	3.2	5.4	-2.3	-1.0
Commuting to job workplace: Public transport	1.8	2.1	3.0	-1.1	-1.7
Alzheimer’s Disease (in mother)	1.7	2.0	3.7	1.9	-0.6
Medication: Levothyroxine sodium	1.7	2.9	4.1	2.0	1.3
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.6	3.2	-1.8	1.4
Qualifications: nursing, teaching	1.7	2.6	4.7	-0.8	-2.2
Alcohol drinker status: Never	1.7	2.1	4.1	-0.2	2.0
Fractured/broken bones in last 5 years	1.7	2.2	2.9	-1.7	1.2
Medication: Omeprazole (e.g. Zanprol)	1.7	2.0	4.0	-0.3	2.0
Neuroticism (Nagel 2018)	1.6	3.8	4.8	-1.7	2.2
Age at First Birth	1.6	2.4	4.2	-2.1	-0.7
Respiratory disease	1.6	3.5	4.6	2.1	1.6
Time employed in main current job	1.6	1.8	2.9	1.7	-0.8
Depression (self-reported)	1.6	1.9	3.6	0.4	1.9
Heart disease (mother)	1.6	2.0	2.1	-1.4	1.4
Age started oral contraceptive pill	1.6	2.0	3.8	-1.9	-0.5
Vascular/heart problems diagnosed by doctor	1.6	4.4	5.5	2.3	1.8
HbA1C	1.5	1.7	2.8	1.7	-0.7
Age at first live birth	1.5	2.7	5.5	-0.0	-2.3
Migraine (self-reported)	1.5	1.9	3.7	1.9	0.1
Medication: Omeprazole	1.5	1.8	3.6	0.1	1.9
Primary Biliary Cirrhosis	1.4	2.0	3.2	1.8	-0.9
Had other major operations	1.4	1.7	2.5	-0.9	1.6
Forced expiratory volume in 1-second (FEV1)	1.4	4.8	8.3	1.2	-2.9
Worry too long after embarrassment	1.4	2.3	4.0	-0.7	-2.0
Pulse wave peak to peak time	1.4	1.6	3.1	-0.4	-1.8
Mean time to correctly identify matches	1.4	2.6	5.0	2.2	0.5
Ever had bowel cancer screening	1.4	1.6	3.1	0.3	1.8
Arm fat mass (left)	1.4	5.8	8.5	1.8	-2.9
Guilty feelings	1.4	2.0	2.3	-1.5	-1.3
Eye problems/disorders: Glaucoma	1.4	1.6	2.4	0.9	1.6
Fasting Glucose	1.3	1.6	3.2	1.8	-0.1
Impedance of leg (left)	1.3	6.3	8.7	-2.0	-3.0
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	3.4	0.9	1.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.2	7.2	1.0	-2.7
Gout (self-reported)	1.3	1.8	1.9	1.4	-1.3
Bipolar Disorder (2018)	1.2	2.0	2.0	1.4	1.4
Chronotype (morning person)	1.2	2.8	5.5	2.3	-0.4
Relative age of first facial hair	1.2	2.5	3.7	1.2	1.9
High blood pressure	1.2	3.3	3.7	-1.9	-1.7
Arm fat mass (right)	1.2	5.0	7.1	1.7	-2.7
Mouth/teeth dental problems: Loose teeth	1.2	1.4	2.1	-0.9	1.4
Medication: Allopurinol	1.2	1.5	1.8	1.1	-1.3
Leg fat mass (right)	1.2	4.5	4.6	2.1	-2.1
Diabetes diagnosed by doctor	1.2	2.0	4.0	0.2	-2.0
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.0	1.4	-0.8
Leg fat mass (left)	1.2	4.6	5.5	1.9	-2.3
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.1	0.5	-1.4
Medication: Co-codamol	1.1	1.3	2.3	0.5	1.5
Impedance of leg (right)	1.1	5.2	8.3	-1.4	-2.9
Qualifications: None of the above	1.1	2.4	3.6	1.1	1.9
Angina (self-reported)	1.1	1.4	2.1	-1.4	0.8
Leg pain on walking	1.1	1.4	2.7	0.2	1.6
Illnesses of father: Heart disease	1.1	1.5	2.2	0.9	1.5
Tinnitus: Yes, now most or all of the time	1.1	1.3	1.8	0.9	-1.3
Depression (Nagel 2018)	1.0	1.5	2.7	-0.6	1.6
Schizophrenia vs Biploar Disorder	1.0	1.3	1.7	-0.9	-1.3
Neuroticism (2016)	1.0	1.4	2.7	0.4	1.6
Ulcerative Colitis	1.0	1.5	2.2	-1.5	-0.9
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	2.0	0.5	1.4
Chronic bronchitis/emphysema (father)	1.0	1.2	2.4	-0.0	1.5
Past tobacco smoking	1.0	1.9	3.3	-1.8	-0.7
Illnesses of siblings	1.0	1.3	2.6	1.6	0.3
Father’s age at death	1.0	1.3	1.4	-1.2	-1.1
Loud music exposure frequency	1.0	1.1	2.2	0.1	1.5
Medication: Ventolin 100micrograms inhaler	1.0	1.2	1.8	-0.8	1.4
Body fat percentage	1.0	3.9	6.8	1.0	-2.6
Medication for pain relief, constipation, heartburn	1.0	1.8	3.6	-0.0	-1.9
Hearing aid user	1.0	1.1	2.1	0.4	1.4
Pain type(s) experienced in last month: Hip pain	1.0	1.3	2.5	0.3	1.6
Diastolic blood pressure, automated reading	1.0	3.1	5.9	-2.4	-0.6
Unable to work because of sickness or disability	1.0	1.3	2.0	-0.8	1.4
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	1.5	-1.2	1.1
Mean Putamen Volume	0.9	1.0	1.8	-1.3	-0.4
Type 2 Diabetes (T2D) (2018)	0.9	1.8	3.3	-0.5	-1.8
Sensitivity / hurt feelings	0.9	1.5	2.4	-0.8	1.6
Supplements: Glucosamine	0.9	1.1	1.4	1.2	-0.9
Waist circumference	0.9	3.3	3.9	1.7	-2.0
Financial difficulties in last 2 years	0.9	1.2	2.4	0.3	1.5
Mouth/teeth dental problems	0.9	1.3	2.1	-1.5	-0.7
Medication: Ramipril	0.9	1.2	1.9	-1.4	-0.7
Qualifications: A levels/AS levels or equivalent	0.9	2.0	2.3	-1.5	-1.3
High blood pressure (siblings)	0.9	1.3	2.2	-1.5	-0.6
Comparative body size at age 10	0.9	2.6	3.1	-1.8	1.5
Qualifications: College or University degree	0.9	2.8	4.8	-0.9	-2.2
Medication: Seretide 50 evohaler	0.9	1.1	1.6	1.3	0.7
Hypertension (Self-reported)	0.9	2.6	3.3	-1.8	-1.3
Reaction Time	0.8	1.6	2.9	1.7	0.6
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.0	-1.0	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.0	0.3	1.4
Nervous feelings	0.8	1.6	2.7	-1.7	-0.6
Neuroticism score	0.8	1.7	2.0	-1.2	1.4
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	1.2	0.9	1.1
Ever highly irritable/argumentative for 2 days	0.8	1.0	1.4	0.8	1.2
Number of full brothers	0.8	1.1	1.7	-1.3	0.6
Handedness (chirality/laterality): Left-handed	0.8	0.9	1.8	1.3	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	1.9	-1.4	0.1
Medication: Aspirin	0.8	1.0	2.0	-1.4	0.3
Supplements: Fish oil (including cod liver oil)	0.8	1.0	1.6	1.3	0.6
Body Mass Index (BMI) (2010)	0.7	0.9	1.7	-0.3	-1.3
Heel T-Score	0.7	5.4	10.6	0.4	3.2
Cardiovascular Disease	0.7	2.2	2.3	-1.5	-1.5
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.3	0.7	1.1
Systolic blood pressure, automated reading	0.7	2.1	2.7	-1.6	1.2
Lung cancer (father)	0.7	0.8	1.5	-1.2	0.1
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	1.4	1.2	0.6
Blood clot in the leg (DVT)	0.7	1.0	1.6	-1.3	0.5
Average weekly champagne plus white wine intake	0.7	0.9	1.4	0.6	-1.2
Miserableness	0.7	1.2	2.1	0.5	1.4
Mother’s age at death	0.7	0.9	1.4	0.7	-1.2
Medication: Blood pressure	0.7	1.3	2.5	-1.6	-0.2
Medication: Atorvastatin	0.7	0.9	1.6	-1.3	-0.4
Risk taking	0.7	1.1	1.3	1.1	0.9
Alzheimer’s Disease (including proxy)	0.6	0.8	1.6	1.3	0.0
HDL Cholesterol	0.6	0.9	1.7	0.4	1.3
Rheumatoid Arthritis	0.6	0.9	1.3	1.1	-0.7
Smoking Status	0.6	1.5	2.9	1.7	0.2
Average weekly spirits intake	0.6	0.7	1.1	-0.6	1.0
Serious illness, injury or assault to yourself	0.6	0.7	1.4	-0.0	1.2
Stomach or abdominal pain in last month	0.6	0.8	1.2	-1.1	0.6
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	0.8	-0.7	0.9
Hair/balding pattern: Pattern 2	0.6	0.7	1.4	-1.2	-0.3
Had menopause	0.6	0.8	1.6	0.2	1.3
Pain all over the body in last month	0.6	0.6	0.9	-0.6	1.0
Fluid intelligence score	0.6	1.2	2.3	1.5	-0.3
Worrier / anxious feelings	0.6	1.1	2.2	-1.5	0.2
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	1.8	-1.4	-0.4
Number of full sisters	0.6	0.8	0.8	-0.9	0.8
Overall health rating	0.6	1.2	1.6	1.3	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.3	-0.1	1.1
Osteoarthritis (self-reported)	0.6	0.7	0.8	-0.9	0.9
Financial situation satisfaction	0.6	0.8	0.9	0.8	1.0
Intelligence (Savage-Jansen 2018)	0.5	1.7	3.0	1.7	-0.6
Schizophrenia (2018)	0.5	1.0	1.9	-0.4	-1.4
Crohns Disease (2017)	0.5	1.0	2.0	1.4	-0.2
Ovarian Cancer	0.5	0.6	0.7	-0.8	-0.8
Triglycerides	0.5	0.8	1.6	-0.2	-1.3
Waist Hip Ratio (WHR)	0.5	2.2	3.1	-1.1	1.8
Tanning	0.5	6.1	12.2	-0.3	3.5
Number of treatments/medications taken	0.5	1.0	1.8	0.4	1.3
Hearing difficulty/problems: Yes	0.5	0.8	1.3	-0.5	1.1
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.0	0.5	1.0
Angina	0.5	0.7	1.1	-1.0	0.6
Medication: Metformin	0.5	0.8	1.1	0.7	-1.0
Maternal smoking around birth	0.5	0.8	1.0	-1.0	0.7
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.9	0.3	1.0
Number of incorrect matches in round	0.5	0.8	1.6	1.2	-0.2
Alcohol usually taken with meals	0.5	0.8	0.8	0.9	-0.9
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	0.6	-0.8	0.8
Birth weight of first child	0.5	0.9	1.5	0.5	-1.2
Chronic bronchitis/emphysema (mother)	0.5	0.6	0.8	0.6	0.9
Exposure to tobacco smoke outside home	0.5	0.7	1.3	0.2	1.1
Family relationship satisfaction	0.5	0.6	0.7	-0.8	0.6
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.2	0.2	-1.1
Medication: Aspirin	0.5	0.6	1.2	-1.1	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.7	1.3	0.1
Ever smoked	0.5	0.8	1.6	1.3	0.3
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.0	0.2	1.0
Pack years of smoking	0.5	0.7	1.0	-1.0	0.6
Blood Platelet Count	0.4	5.0	5.3	2.2	2.3
BMI	0.4	2.5	4.0	2.0	1.0
Systolic Blood Pressure	0.4	2.2	3.9	-2.0	-0.7
Fed-up feelings	0.4	0.8	1.2	-0.6	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	1.7	0.4	1.3
Mouth/teeth dental problems: Dentures	0.4	0.7	1.4	-0.1	1.2
Pulse wave Arterial Stiffness index	0.4	0.5	0.7	0.5	0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.3	1.1	0.2
Health satisfaction	0.4	0.5	0.9	1.0	0.3
Illnesses of siblings: Diabetes	0.4	0.5	0.7	-0.9	0.5
Long-standing illness, disability or infirmity	0.4	0.6	1.2	-0.3	1.1
Friendships satisfaction	0.4	0.5	1.0	-0.2	1.0
Osteoporosis (self-reported)	0.4	0.6	1.1	0.2	-1.0
Medication: Gliclazide	0.4	0.4	0.7	0.3	-0.8
Number of self-reported non-cancer illnesses	0.4	0.8	1.5	0.2	1.2
Myopia	0.4	0.6	1.1	-0.1	-1.1
Cholesterol lowering medication	0.4	0.6	1.2	-1.1	-0.2
Alcohol drinker status: Previous	0.4	0.5	0.7	0.8	0.6
Breast Cancer	0.3	0.7	0.9	0.6	1.0
LDL Cholesterol	0.3	0.5	0.9	-1.0	-0.1
Lupus	0.3	0.5	0.6	-0.8	0.6
Blood Eosinophil Count	0.3	2.0	4.1	2.0	0.1
Blood Red Count	0.3	2.5	3.8	-1.1	-1.9
Pack years adult smoking proportion	0.3	0.4	0.6	-0.8	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	0.7	0.9	0.7
Qualifications: CSEs or equivalent	0.3	0.4	0.7	-0.2	0.9
Hearing difficulty/problems with background noise	0.3	0.5	0.9	0.4	1.0
Medication: Lansoprazole	0.3	0.3	0.6	-0.1	-0.8
Length of working week for main job	0.3	0.3	0.6	0.3	0.8
Pulse wave reflection index	0.3	0.4	0.6	0.3	0.8
Pulse rate, automated reading	0.3	0.9	1.4	0.5	1.2
Alcohol intake frequency.	0.3	0.6	1.1	1.1	0.3
Arm fat percentage (left)	0.3	1.1	1.6	0.7	-1.3
Smoking status: Current	0.3	0.4	0.6	-0.7	0.5
Average weekly beer plus cider intake	0.3	0.4	0.6	-0.8	-0.4
Alzheimer’s Disease (in father)	0.2	0.2	0.3	-0.4	0.5
Irritable Bowel Disease (IBD)	0.2	0.5	0.7	0.8	-0.6
Ulcerative Colitis (UC)	0.2	0.3	0.3	-0.6	-0.5
Crohns Disease (2012)	0.2	0.4	0.7	0.8	0.2
Hand grip strength (right)	0.2	0.6	1.0	0.5	-1.0
Current tobacco smoking	0.2	0.3	0.5	-0.7	0.4
Average weekly fortified wine intake	0.2	0.2	0.3	0.4	-0.5
Relative age voice broke	0.2	0.3	0.4	0.6	0.4
Body mass index (BMI)	0.2	0.8	1.1	1.1	0.7
Medication: Simvastatin	0.2	0.3	0.5	-0.7	-0.2
Arm fat percentage (right)	0.2	0.8	1.2	0.7	-1.1
Alcohol intake versus 10 years previously	0.2	0.3	0.5	-0.2	0.7
Hair/balding pattern: Pattern 3	0.2	0.3	0.5	0.7	0.0
Happiness	0.2	0.3	0.5	-0.1	0.7
Asthma	0.2	0.3	0.5	0.7	0.4
Illnesses of mother	0.2	0.3	0.5	-0.7	-0.3
Breastfed as a baby	0.2	0.2	0.2	0.4	-0.5
Peak expiratory flow (PEF)	0.2	0.4	0.7	0.3	-0.9
Leg fat percentage (right)	0.2	0.6	1.0	1.0	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.5	-0.7	-0.1
Eye problems/disorders: None of the above	0.2	0.2	0.4	0.7	0.1
Chest pain or discomfort	0.2	0.3	0.3	0.5	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	0.6	0.2
Commuting to job workplace: Walk	0.2	0.2	0.4	-0.6	-0.3
Breast cancer (self-reported)	0.2	0.3	0.5	0.3	-0.7
Asthma (self-reported)	0.2	0.4	0.5	0.7	0.4
Heart disease (siblings)	0.2	0.2	0.5	0.7	0.0
Bipolar Disorder or Schizophrenia	0.1	0.3	0.5	0.7	-0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.4	0.6	-0.1
Schizophrenia (2014)	0.1	0.1	0.2	0.2	-0.5
Blood White Count	0.1	0.8	1.7	-0.1	1.3
Allergy or Eczema	0.1	0.2	0.3	0.4	0.6
Hand grip strength (left)	0.1	0.3	0.4	0.6	0.5
Vitamin and mineral supplements	0.1	0.1	0.1	-0.2	0.4
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.2	-0.4	-0.3
Multivitamins +/- minerals	0.1	0.1	0.2	-0.1	0.4
High blood pressure (mother)	0.1	0.2	0.3	-0.1	-0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.2	0.2	-0.5
Pulse rate	0.1	0.2	0.3	0.6	0.4
Hair/balding pattern: Pattern 4	0.1	0.2	0.4	-0.6	0.0
Headache pain in last month	0.1	0.3	0.5	0.2	0.7
Glaucoma (self-reported)	0.1	0.1	0.2	0.5	-0.1
Shortness of breath walking on level ground	0.1	0.1	0.1	0.2	0.4
Emphysema/chronic bronchitis	0.1	0.1	0.1	0.3	0.3
Supplements: Vitamin C	0.1	0.1	0.1	-0.3	0.2
Mineral and other dietary supplements	0.1	0.2	0.3	-0.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.4	0.4	0.6
Wears glasses or contact lenses	0.1	0.2	0.2	0.5	0.3
Medication: Lisinopril	0.1	0.1	0.1	-0.3	-0.2
Illnesses of father: High blood pressure	0.1	0.2	0.3	-0.6	-0.2
Leg fat percentage (left)	0.1	0.4	0.7	0.8	-0.5
Pain experienced in last month	0.1	0.2	0.3	-0.1	-0.6
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	-0.1	-0.2
Lung FVC	0.0	0.2	0.3	-0.1	-0.6
Hair Pigment	0.0	0.1	0.1	0.2	0.3
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	0.1	-0.1
Severe depression (siblings)	0.0	0.0	0.1	-0.3	0.1
Allergy	0.0	0.1	0.1	-0.0	-0.4
Falls in the last year	0.0	0.0	0.1	0.1	0.3
Number of live births	0.0	0.0	0.1	0.2	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.1	0.0	-0.3
Medication: Cholesterol lowering	0.0	0.1	0.1	-0.3	0.1
Neck or shoulder pain in last month	0.0	0.0	0.0	-0.1	-0.2
Medication: Ibuprofen	0.0	0.1	0.1	0.1	0.3
Average weekly red wine intake	0.0	0.0	0.1	0.3	0.1
Eye problems/disorders: Cataract	0.0	0.0	0.1	-0.0	-0.3
Medication for cholesterol	0.0	0.0	0.1	-0.3	0.1
Back pain experienced in last month	0.0	0.1	0.1	-0.3	-0.0
Illnesses of father: None of the above (group 1)	0.0	0.0	0.0	-0.2	-0.2
High cholesterol (Self-reported)	0.0	0.0	0.0	0.2	-0.0
Medication: Bendroflumethiazide	0.0	0.1	0.1	-0.4	0.0
Supplements: Calcium	0.0	0.0	0.0	-0.2	0.0

Hub : Genes

HIVEP2

Models

Trait associations