[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr6:160,071,844-161,571,560

Best TWAS P=1.11e-14 · Best GWAS P=1.19e-17 conditioned to 1.33e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum SLC22A3 0.13 0.06 enet 7 0.09 1.3e-05 -6.0 -6.1 9.1e-10 -0.63 0.57 0.42 FALSE
2 GTEx Brain Caudate basal ganglia SLC22A3 0.15 0.10 enet 39 0.11 5.6e-04 -7.1 -7.7 1.1e-14 -0.71 0.06 0.86 TRUE
3 GTEx Brain Frontal Cortex BA9 SLC22A3 0.26 0.08 lasso 6 0.05 1.5e-02 -4.5 -6.4 1.8e-10 -0.63 0.14 0.61 FALSE
4 GTEx Colon Transverse SLC22A3 0.18 0.00 enet 11 0.00 5.2e-01 4.2 -5.4 5.3e-08 -0.40 0.09 0.42 FALSE
5 GTEx Esophagus Mucosa SLC22A3 0.19 0.08 enet 47 0.12 1.7e-08 6.1 -6.6 3.3e-11 -0.58 0.55 0.44 FALSE
6 GTEx Nerve Tibial SLC22A3 0.20 0.10 lasso 7 0.13 3.2e-09 -6.0 -6.4 1.4e-10 -0.56 0.99 0.00 FALSE
7 GTEx Ovary SLC22A3 0.33 0.29 lasso 6 0.23 2.8e-06 -5.7 -5.9 4.8e-09 -0.65 0.14 0.76 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic SLC22A3 0.15 0.05 lasso 9 0.05 9.9e-04 -3.9 -6.4 1.2e-10 -0.65 0.06 0.92 FALSE
9 GTEx Skin Sun Exposed Lower leg SLC22A3 0.29 0.14 lasso 10 0.20 3.7e-16 3.8 -5.7 9.0e-09 -0.48 1.00 0.00 FALSE
10 GTEx Testis SLC22A3 0.19 0.01 lasso 14 0.05 2.6e-03 -8.4 -5.9 3.8e-09 -0.66 0.07 0.92 FALSE
11 ROSMAP Brain Pre-frontal Cortex SLC22A3 0.14 0.20 lasso 10 0.19 2.4e-24 -6.0 -6.3 2.8e-10 -0.67 1.00 0.00 FALSE
12 The Cancer Genome Atlas Colon Adenocarcinoma SLC22A3 0.17 0.06 lasso 5 0.04 2.8e-03 -4.2 5.1 2.7e-07 0.45 0.07 0.19 FALSE
13 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LPAL2 0.07 0.00 blup 74 0.04 1.1e-03 -3.7 5.9 3.7e-09 0.75 0.04 0.53 FALSE