[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr7:2,032,803-3,581,391

Best TWAS P=5.08e-42 · Best GWAS P=2.02e-41 conditioned to 0.0148

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	AMZ1	0.19	0.12	enet	22	0.13	5.7e-16	6.4	8.0	1.9e-15	-0.45	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	GNA12	0.11	0.08	lasso	4	0.07	1.3e-06	-8.4	-9.2	2.4e-20	0.73	0.30	0.70	FALSE
3	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	-13.4	-11.5	1.7e-30	0.86	0.02	0.98	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	-13.4	-13.3	1.8e-40	0.95	0.01	0.99	FALSE
5	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	-13.4	-11.2	6.0e-29	0.88	0.02	0.98	FALSE
6	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	-8.2	-11.1	1.4e-28	0.83	0.04	0.87	FALSE
7	GTEx	Colon Transverse	GNA12	0.19	0.08	lasso	4	0.10	2.3e-05	6.5	-7.6	3.1e-14	0.62	0.32	0.65	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	-8.4	-11.3	2.2e-29	0.84	0.04	0.94	FALSE
9	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	-13.2	-12.1	7.1e-34	0.88	0.02	0.98	FALSE
10	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	-13.4	-13.0	9.9e-39	0.96	0.01	0.99	FALSE
11	GTEx	Lung	GNA12	0.16	0.08	enet	21	0.12	1.2e-09	-13.1	-11.1	1.2e-28	0.77	0.03	0.97	FALSE
12	GTEx	Nerve Tibial	GNA12	0.31	0.34	lasso	7	0.36	9.6e-27	-8.4	-10.9	6.9e-28	0.84	0.89	0.11	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	GNA12	0.10	0.15	lasso	3	0.12	4.2e-07	6.5	-7.2	6.5e-13	0.51	0.43	0.54	FALSE
14	GTEx	Skin Sun Exposed Lower leg	GNA12	0.17	0.16	lasso	3	0.18	1.3e-14	-8.3	-11.0	5.0e-28	0.88	0.16	0.84	FALSE
15	GTEx	Small Intestine Terminal Ileum	GNA12	0.34	0.20	lasso	5	0.16	2.4e-04	-8.5	-9.1	9.4e-20	0.74	0.09	0.71	FALSE
16	GTEx	Stomach	GNA12	0.18	0.16	lasso	2	0.13	6.6e-07	-8.2	-8.3	1.0e-16	0.67	0.52	0.47	FALSE
17	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	-13.2	-13.2	1.7e-39	0.95	0.02	0.92	FALSE
18	METSIM	Adipose	GNA12	0.07	0.05	lasso	3	0.05	3.3e-08	-8.5	-8.6	1.1e-17	0.75	0.19	0.81	FALSE
19	NTR	Blood	GNA12	0.07	0.03	bslmm	597	0.06	1.3e-17	-9.6	-9.5	1.5e-21	0.61	0.94	0.06	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	-13.4	13.6	5.1e-42	-0.92	0.01	0.99	TRUE
21	YFS	Blood	GNA12	0.23	0.15	bslmm	570	0.25	4.5e-82	6.0	-8.5	2.2e-17	0.51	1.00	0.00	FALSE
22	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	8.4	-11.7	1.7e-31	0.74	0.01	0.70	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GNA12	0.03	0.04	lasso	1	0.04	3.0e-05	-8.4	-8.4	4.6e-17	0.69	0.10	0.71	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	AMZ1	0.04	0.04	lasso	3	0.02	1.3e-03	8.4	9.7	3.0e-22	-0.63	0.03	0.91	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	5.4	-10.7	1.2e-26	0.78	0.06	0.75	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	AMZ1	0.08	0.01	blup	71	0.05	1.3e-05	-8.4	6.1	8.2e-10	-0.64	0.05	0.76	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	AMZ1	0.32	0.04	enet	19	0.20	3.3e-19	-9.6	5.8	6.4e-09	-0.56	0.18	0.82	FALSE