[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr12:53,025,391-54,539,005

Best TWAS P=1.56e-11 · Best GWAS P=3.24e-10 conditioned to 0.0687

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PRR13	0.13	0.10	lasso	7	0.09	9.2e-08	5.2	-5.7	1.0e-08	0.35	0.67	0.33	FALSE
2	GTEx	Artery Aorta	SP1	0.14	0.14	lasso	8	0.14	2.2e-08	5.0	5.2	1.8e-07	-0.24	0.77	0.23	FALSE
3	GTEx	Artery Aorta	PRR13	0.23	0.28	enet	39	0.30	4.3e-17	5.2	-5.7	9.6e-09	0.32	0.54	0.46	FALSE
4	GTEx	Artery Coronary	SP1	0.17	0.12	lasso	4	0.12	8.6e-05	4.9	6.1	1.4e-09	-0.31	0.17	0.58	FALSE
5	GTEx	Artery Tibial	PRR13	0.15	0.18	enet	21	0.22	5.4e-17	5.2	-5.2	2.5e-07	0.31	0.48	0.52	FALSE
6	GTEx	Breast Mammary Tissue	SP1	0.12	0.13	lasso	5	0.08	9.5e-05	5.0	5.8	5.0e-09	-0.23	0.72	0.23	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	PRR13	0.22	0.16	lasso	4	0.18	3.2e-07	5.2	-6.1	7.8e-10	0.29	0.25	0.17	FALSE
8	GTEx	Esophagus Muscularis	PRR13	0.13	0.15	lasso	2	0.14	9.2e-09	5.2	-5.3	1.1e-07	0.23	0.51	0.48	FALSE
9	GTEx	Nerve Tibial	PRR13	0.17	0.21	lasso	3	0.20	2.7e-14	5.2	-5.2	2.0e-07	0.22	0.49	0.51	FALSE
10	GTEx	Skin Sun Exposed Lower leg	PRR13	0.22	0.08	lasso	5	0.17	6.5e-14	4.8	-5.6	2.2e-08	0.30	0.72	0.28	FALSE
11	GTEx	Thyroid	SP1	0.11	0.05	lasso	7	0.04	8.2e-04	4.9	5.2	2.2e-07	-0.23	0.41	0.47	FALSE
12	GTEx	Thyroid	PRR13	0.22	0.18	lasso	9	0.24	4.8e-18	4.9	-5.6	2.3e-08	0.31	0.79	0.21	FALSE
13	METSIM	Adipose	SP7	0.03	0.02	lasso	2	0.01	6.1e-03	5.1	-5.5	2.9e-08	0.15	0.23	0.07	TRUE
14	YFS	Blood	SP1	0.22	0.17	bslmm	398	0.18	1.4e-56	5.0	5.2	1.9e-07	-0.16	0.53	0.46	FALSE
15	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PRR13	0.13	0.04	blup	28	0.07	3.3e-06	4.9	-6.2	6.7e-10	0.58	0.07	0.39	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PRR13	0.03	0.03	blup	28	0.04	4.6e-05	4.9	-5.5	4.0e-08	0.37	0.39	0.18	FALSE
17	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PRR13	0.05	0.03	blup	28	0.04	4.1e-03	5.2	-6.2	5.0e-10	0.47	0.03	0.13	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	PRR13	0.07	0.04	blup	28	0.05	4.7e-06	5.2	-6.7	1.6e-11	0.60	0.34	0.33	TRUE
19	The Cancer Genome Atlas	Rectum Adenocarcinoma	PCBP2	0.25	0.04	blup	36	0.10	2.3e-03	-6.3	-6.3	2.9e-10	0.64	0.00	0.54	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	PCBP2	0.04	0.01	enet	6	0.02	4.8e-03	3.7	-6.4	1.4e-10	0.63	0.01	0.58	FALSE