[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr12:109,231,851-113,517,494

Best TWAS P=1.3e-10 · Best GWAS P=2.86e-15 conditioned to 0.0101

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland PPTC7 0.13 -0.01 lasso 6 0.00 3.4e-01 4.6 5.3 1.2e-07 -0.19 0.03 0.12 FALSE
2 GTEx Artery Tibial VPS29 0.05 0.03 lasso 3 0.02 5.9e-03 5.4 5.4 6.5e-08 -0.07 0.01 0.96 TRUE
3 GTEx Artery Tibial HECTD4 0.05 0.02 lasso 3 0.01 3.1e-02 -7.1 -6.4 1.3e-10 0.85 0.02 0.92 TRUE
4 GTEx Brain Cerebellar Hemisphere MMAB 0.31 0.27 lasso 3 0.24 6.6e-07 5.4 -5.4 8.2e-08 -0.06 0.02 0.98 FALSE
5 GTEx Brain Nucleus accumbens basal ganglia MMAB 0.40 0.24 enet 16 0.28 2.5e-08 4.8 -5.4 6.9e-08 -0.01 0.06 0.83 FALSE
6 GTEx Colon Sigmoid KCTD10 0.25 0.16 lasso 8 0.15 6.2e-06 5.2 -5.6 1.8e-08 -0.03 0.06 0.92 FALSE
7 GTEx Colon Transverse MMAB 0.08 0.07 lasso 2 0.05 1.7e-03 5.2 -5.3 9.1e-08 -0.04 0.07 0.82 FALSE
8 GTEx Muscle Skeletal VPS29 0.06 0.06 lasso 3 0.05 4.3e-06 5.4 5.1 2.6e-07 -0.04 0.00 0.99 FALSE
9 GTEx Thyroid VPS29 0.07 0.01 lasso 5 0.01 8.9e-02 4.5 5.2 1.8e-07 -0.06 0.01 0.87 FALSE
10 NTR Blood ALDH2 0.06 0.01 blup 222 0.02 4.3e-08 4.4 5.9 3.1e-09 -0.60 0.37 0.62 FALSE
11 NTR Blood UBE3B 0.09 0.05 lasso 8 0.08 1.0e-25 5.0 5.9 3.2e-09 0.02 0.03 0.97 TRUE
12 The Cancer Genome Atlas Bladder Urothelial Carcinoma KCTD10 0.06 0.00 lasso 3 0.00 1.4e-01 5.0 -5.4 5.1e-08 -0.05 0.01 0.65 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MMAB 0.04 0.02 blup 53 0.02 5.2e-03 5.2 -5.3 1.4e-07 -0.05 0.02 0.55 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma CUX2 0.08 0.01 blup 95 0.02 1.3e-03 4.2 5.8 7.5e-09 -0.16 0.02 0.76 TRUE
15 The Cancer Genome Atlas Prostate Adenocarcinoma MMAB 0.06 0.06 blup 57 0.06 5.4e-07 -5.0 -5.9 3.3e-09 -0.03 0.06 0.94 FALSE