Best TWAS P=3.55e-17 · Best GWAS P=2.1e-17 conditioned to 0.217
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | EDNRB | 0.05 | 0.03 | bslmm | 465 | 0.04 | 3.1e-06 | -7.0 | 7.5 | 4.5e-14 | -0.61 | 0.4 | 0.58 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EDNRB | 0.02 | 0.00 | blup | 60 | 0.00 | 3.1e-02 | -8.5 | 8.4 | 3.5e-17 | -0.90 | 0.0 | 0.75 | TRUE |