[Hub]/) : Traits : Leg predicted mass (left) :

chr17:36,211,659-37,644,854

Best TWAS P=2.53e-10 · Best GWAS P=4.1e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PIP4K2B 0.15 0.07 lasso 5 0.07 2.2e-06 -6.2 -5.8 5.2e-09 0.92 0 1.00 FALSE
2 GTEx Artery Aorta PSMB3 0.23 0.17 enet 26 0.22 2.1e-12 -6.2 -5.8 5.8e-09 0.83 0 1.00 FALSE
3 GTEx Artery Tibial PSMB3 0.10 0.02 enet 12 0.03 1.2e-03 -6.2 -5.8 7.6e-09 0.73 0 0.99 FALSE
4 GTEx Testis PSMB3 0.30 0.24 lasso 4 0.21 8.9e-10 -6.2 -6.3 2.5e-10 0.97 0 1.00 TRUE
5 NTR Blood PIP4K2B 0.02 0.01 lasso 3 0.01 6.4e-04 -6.2 6.2 5.2e-10 -0.94 0 0.99 FALSE
6 The Cancer Genome Atlas Prostate Adenocarcinoma PIP4K2B 0.05 0.04 blup 56 0.05 5.3e-06 -4.4 -5.5 3.3e-08 0.85 0 0.99 FALSE
7 The Cancer Genome Atlas Testicular Germ Cell Tumors PSMB3 0.12 0.09 lasso 3 0.06 3.0e-03 -6.2 -6.3 3.3e-10 0.99 0 0.94 FALSE
8 The Cancer Genome Atlas Thyroid Carcinoma PSMB3 0.05 0.06 lasso 1 0.05 2.4e-05 -6.2 -6.2 4.2e-10 0.97 0 1.00 FALSE