TWAS hub - PSMB3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1140	0.0400	1.4e-03	0.010	NA	0.027	NA	0.022	4.4e-02	NA	2.7e-03	NA	6.3e-03
2	GTEx	Adipose Visceral Omentum	0.1410	0.0570	7.5e-03	0.005	NA	0.029	NA	0.017	1.6e-01	NA	1.2e-02	NA	4.4e-02
3	GTEx	Artery Aorta	0.2340	0.0560	7.5e-07	0.171	NA	0.221	NA	0.191	1.0e-09	NA	2.1e-12	NA	9.5e-11
4	GTEx	Artery Tibial	0.1034	0.0325	1.9e-04	0.016	NA	0.033	NA	0.031	1.8e-02	NA	1.2e-03	NA	1.6e-03
5	GTEx	Spleen	0.3400	0.1070	9.9e-04	-0.012	NA	0.029	NA	0.045	9.5e-01	NA	6.1e-02	NA	2.7e-02
6	GTEx	Testis	0.3040	0.0760	6.0e-06	0.240	NA	0.111	NA	0.212	4.9e-11	NA	1.3e-05	NA	8.9e-10
7	METSIM	Adipose	0.0398	0.0164	2.8e-03	0.017	0.011	0.004	0.010	0.015	1.2e-03	8.6e-03	8.4e-02	1.0e-02	2.3e-03
8	NTR	Blood	0.0325	0.0111	3.9e-04	0.006	0.004	0.008	0.009	0.007	4.6e-03	1.5e-02	1.2e-03	4.1e-04	1.4e-03
9	YFS	Blood	0.1411	0.0231	0.0e+00	0.112	0.127	0.157	0.150	0.146	1.1e-34	2.2e-39	7.2e-49	1.1e-46	3.0e-45
10	TCGA	Bladder Urothelial Carcinoma	0.0420	0.0210	1.3e-03	-0.001	0.021	0.005	NA	0.004	4.1e-01	6.7e-03	1.0e-01	NA	1.3e-01
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.1421	0.0563	4.0e-07	0.050	0.054	0.050	NA	0.031	2.7e-06	8.9e-07	2.4e-06	NA	2.0e-04
12	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1230	0.0530	8.7e-04	0.016	0.044	0.045	NA	0.023	4.2e-02	1.5e-03	1.3e-03	NA	1.7e-02
13	TCGA	Prostate Adenocarcinoma	0.1088	0.0449	2.0e-06	0.072	0.069	0.064	NA	0.066	5.8e-08	9.4e-08	2.7e-07	NA	1.8e-07
14	TCGA	Testicular Germ Cell Tumors	0.1150	0.0590	5.9e-03	0.092	0.037	0.018	NA	0.063	3.9e-04	1.8e-02	7.7e-02	NA	3.0e-03
15	TCGA	Thyroid Carcinoma	0.0480	0.0240	5.9e-04	0.057	0.036	0.031	NA	0.046	3.3e-06	1.7e-04	4.9e-04	NA	2.4e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Hand grip strength (left)	13.0	34.1	60.7	-5.9	-2.4	-6.4	-6.3	-1.0	-7.8	-3.5	-1.3	-6.2	-6.3	-6.0	-6.1	-6.8	-7.7	-7.7
Hand grip strength (right)	11.4	31.0	57.2	-5.0	-3.1	-6.2	-6.0	-1.9	-7.6	-4.0	-0.7	-6.3	-5.6	-5.5	-5.8	-6.0	-7.2	-7.4
Mouth/teeth dental problems: Dentures	6.5	10.9	19.5	-2.6	-2.6	-4.4	-4.2	-2.1	-4.2	-2.7	-2.2	-3.6	-3.5	-2.9	-1.8	-3.0	-4.0	-4.2
Height	6.4	124.0	222.0	-7.9	-6.8	-13.1	-12.3	-5.0	-14.8	-11.0	-3.4	-11.4	-10.0	-12.7	-11.1	-10.0	-14.9	-14.7
Lupus	6.1	9.3	13.8	-3.3	-1.9	-3.0	-3.7	-3.2	-3.2	-1.8	-1.7	-3.2	-3.0	-3.5	-3.5	-3.0	-3.6	-3.2
Sitting height	6.1	43.2	94.5	-3.5	-4.9	-7.5	-7.2	-1.9	-9.7	-6.7	0.3	-5.6	-4.8	-6.8	-7.1	-5.8	-9.3	-9.5
Pulse wave reflection index	5.7	7.0	13.6	3.4	0.9	2.8	2.0	0.3	2.7	2.0	1.6	3.0	3.7	3.5	2.5	3.2	3.0	2.7
Comparative height size at age 10	5.5	30.2	51.8	-4.2	-5.2	-6.2	-6.8	-1.3	-7.2	-5.9	-2.7	-5.0	-5.3	-5.5	-5.0	-4.6	-7.0	-7.1
Trunk fat-free mass	5.4	31.0	59.9	-4.5	-4.4	-6.6	-6.8	-2.0	-7.7	-5.5	-1.6	-4.5	-4.8	-5.2	-5.0	-5.4	-7.5	-7.5
Lung FEV1/FVC ratio	5.3	26.8	57.3	6.8	3.8	6.2	5.7	1.4	7.2	3.6	2.4	5.9	5.7	3.2	0.3	3.5	7.6	7.1
Trunk predicted mass	5.2	29.7	58.4	-4.5	-4.2	-6.5	-6.7	-1.9	-7.6	-5.3	-1.6	-4.4	-4.7	-5.1	-4.9	-5.3	-7.4	-7.5
Standing height	5.1	51.0	104.0	-4.5	-4.8	-8.3	-8.0	-2.3	-10.2	-7.5	-1.0	-6.5	-5.8	-7.5	-7.0	-6.6	-9.8	-10.0
Whole body water mass	5.0	28.7	52.4	-4.5	-4.1	-6.3	-6.6	-1.9	-7.2	-5.4	-2.0	-4.5	-4.9	-5.1	-4.9	-5.0	-7.1	-7.1
Whole body fat-free mass	4.9	28.2	51.3	-4.5	-4.1	-6.3	-6.6	-1.8	-7.2	-5.5	-2.0	-4.4	-4.8	-5.0	-4.9	-4.9	-7.0	-7.0
Forced expiratory volume in 1-second (FEV1), predicted	4.8	9.9	16.9	-2.0	-3.1	-3.6	-3.0	-1.2	-3.8	-3.1	-0.1	-2.8	-2.1	-4.1	-4.1	-3.3	-4.0	-3.8
Leg predicted mass (right)	4.8	25.7	42.5	-4.5	-3.9	-6.1	-6.2	-1.9	-6.5	-5.2	-2.6	-4.7	-4.9	-4.8	-4.7	-4.5	-6.5	-6.4
Waist Hip Ratio (WHR)	4.7	21.1	30.6	3.8	4.5	5.1	5.3	4.4	5.4	3.1	2.2	5.1	3.8	4.5	4.8	4.8	5.1	5.5
Diverticular disease/diverticulitis (self-reported)	4.7	5.6	12.8	-1.1	-1.9	-2.4	-1.8	0.8	-2.7	-1.6	-1.0	-2.8	-2.6	-3.6	-3.3	-2.3	-2.7	-2.8
Leg fat-free mass (right)	4.7	25.1	41.1	-4.5	-3.9	-6.0	-6.1	-1.9	-6.4	-5.2	-2.5	-4.6	-4.8	-4.8	-4.7	-4.5	-6.4	-6.3
Basal metabolic rate	4.5	24.8	43.7	-4.4	-3.8	-5.9	-6.1	-1.4	-6.6	-5.1	-2.1	-4.2	-4.7	-4.8	-4.6	-4.7	-6.5	-6.5
Heel T-Score	4.4	35.1	64.3	5.7	3.9	7.0	6.5	0.6	8.0	3.6	2.8	6.5	6.7	5.7	4.7	5.6	7.9	8.0
Leg fat-free mass (left)	4.3	23.0	40.1	-4.3	-3.6	-5.8	-5.8	-1.3	-6.3	-4.9	-2.0	-4.2	-4.5	-4.5	-4.4	-4.4	-6.3	-6.2
Leg predicted mass (left)	4.3	22.9	39.9	-4.3	-3.5	-5.8	-5.8	-1.2	-6.3	-4.9	-2.0	-4.2	-4.5	-4.5	-4.3	-4.4	-6.3	-6.2
Arm fat-free mass (left)	3.8	19.4	34.5	-3.8	-3.7	-5.1	-5.6	-1.2	-5.9	-4.7	-1.6	-3.4	-4.0	-4.1	-4.0	-4.1	-5.8	-5.7
Arm predicted mass (left)	3.8	19.3	34.7	-3.8	-3.8	-5.1	-5.6	-1.4	-5.9	-4.5	-1.4	-3.4	-4.0	-4.2	-4.0	-4.1	-5.8	-5.8
Supplements: Glucosamine	3.7	4.8	9.4	1.5	3.1	1.8	2.9	0.8	2.7	0.7	-0.1	2.4	2.5	2.3	1.4	2.5	2.8	2.7
Eye problems/disorders: Glaucoma	3.7	4.4	10.1	2.9	1.5	2.4	3.2	1.9	2.3	1.7	1.0	1.6	1.9	2.3	1.6	1.8	2.1	2.2
Arm fat-free mass (right)	3.5	18.0	33.3	-3.6	-3.7	-4.9	-5.4	-1.2	-5.8	-4.7	-1.0	-3.0	-3.7	-4.1	-3.9	-3.7	-5.6	-5.6
Arm predicted mass (right)	3.5	18.1	33.4	-3.6	-3.7	-5.0	-5.7	-1.3	-5.8	-4.7	-1.2	-3.0	-3.8	-4.0	-3.7	-3.6	-5.6	-5.6
Forced vital capacity (FVC), Best measure	3.2	11.6	25.6	-1.8	-1.9	-3.2	-3.2	-0.1	-5.1	-2.2	1.6	-3.4	-2.0	-3.6	-4.3	-4.2	-5.0	-4.9
Commuting to job workplace: Public transport	3.2	3.9	9.9	3.1	1.8	1.8	1.8	2.2	1.7	1.9	0.8	1.3	2.0	2.4	2.3	1.7	1.9	1.8
Ever had prostate specific antigen (PSA) test	3.1	3.6	7.9	-2.3	-0.2	-2.4	-2.6	-0.3	-2.8	-1.3	-0.6	-1.9	-1.9	-1.5	-0.9	-1.2	-2.6	-2.7
Forced vital capacity (FVC)	2.9	11.3	26.1	-1.9	-1.5	-3.4	-3.1	-0.7	-5.1	-2.5	1.5	-3.1	-1.9	-3.6	-4.2	-3.6	-5.0	-5.0
Glaucoma (self-reported)	2.8	3.3	8.9	2.5	1.1	2.3	3.0	1.3	2.0	1.9	1.1	1.3	1.7	1.8	0.8	1.4	1.8	1.9
Friendships satisfaction	2.7	3.3	7.7	0.6	2.5	1.7	1.2	1.5	1.7	2.8	1.3	2.3	1.4	2.3	2.4	0.9	1.4	1.8
Eye problems/disorders: Cataract	2.7	3.1	5.3	-1.6	-0.2	-2.0	-1.1	-0.6	-1.9	-2.3	-1.8	-1.9	-2.1	-2.0	-1.9	-2.1	-1.7	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.7	3.2	7.1	-2.4	-1.9	-1.6	-1.7	0.1	-2.3	-2.0	0.7	-0.8	-1.8	-1.5	-2.1	-1.2	-2.7	-2.2
Number of operations (self-reported)	2.7	4.1	8.7	-2.9	-1.9	-2.4	-1.9	0.9	-2.0	-2.7	-1.6	-1.9	-2.2	-2.2	-0.9	-0.9	-2.5	-2.0
Tinnitus: Yes, but not now, but have in the past	2.3	2.4	6.0	1.4	2.2	0.9	2.5	0.6	1.3	2.1	1.7	0.7	1.6	1.0	2.4	0.5	1.5	1.2
Weight	2.3	11.5	17.2	-3.4	-2.4	-3.9	-3.8	0.1	-4.1	-3.6	-2.3	-3.0	-3.7	-3.4	-3.3	-3.3	-4.0	-4.2
Birth weight of first child	2.3	4.2	10.0	-1.5	-1.0	-2.4	-2.1	1.7	-3.0	-2.8	0.6	-1.6	-1.4	-1.6	-0.7	-1.7	-3.2	-2.8
Medication: Omeprazole	2.3	2.8	4.6	-1.1	-1.2	-1.9	-2.1	-0.9	-1.8	-1.0	-1.6	-1.6	-1.8	-2.0	-2.0	-1.4	-2.1	-1.8
Qualifications: nursing, teaching	2.3	3.5	6.2	2.4	2.1	0.9	2.1	2.5	1.5	1.3	2.3	1.3	2.2	1.7	2.1	1.6	1.6	1.5
Sensitivity / hurt feelings	2.2	3.8	7.7	-2.1	-0.2	-2.5	-1.3	0.3	-2.4	-1.0	-0.9	-2.3	-2.2	-2.2	-1.7	-2.1	-2.8	-2.5
Impedance of leg (left)	2.2	10.6	18.2	3.1	3.1	4.1	4.3	2.4	3.9	2.4	2.1	2.8	3.0	2.5	2.8	3.1	4.1	3.9
Fluid intelligence score	2.2	4.6	11.7	2.5	0.4	2.6	1.9	0.5	1.1	2.4	3.0	2.8	3.4	3.1	1.2	1.7	1.2	1.3
Chest pain or discomfort	2.2	3.2	14.7	-3.8	0.0	-1.9	-1.3	0.3	-1.6	-1.5	-1.8	-1.6	-2.6	-1.1	-0.4	-0.5	-2.4	-1.6
Medication: Omeprazole (e.g. Zanprol)	2.2	2.6	5.8	-1.5	-0.5	-1.5	-1.8	-0.5	-1.7	-0.6	-1.6	-1.7	-1.7	-1.8	-2.4	-1.4	-2.3	-1.8
Schizophrenia vs Biploar Disorder	2.1	2.8	11.7	-0.8	-0.8	-1.9	-1.8	-2.0	-0.5	-2.7	-3.4	-1.6	-2.1	-1.4	0.2	0.1	-0.5	-0.6
Type 2 Diabetes (T2D) (2012)	2.1	2.4	5.0	1.5	1.9	1.7	1.7	2.2	0.9	1.0	1.4	1.5	2.0	1.6	2.1	0.1	1.2	0.9
Wears glasses or contact lenses	2.0	2.3	4.5	-1.5	-0.8	-1.7	0.2	-1.5	-1.0	-1.4	-1.9	-2.1	-1.7	-1.9	-1.8	-2.1	-0.9	-1.2
Primary Biliary Cirrhosis	1.9	2.7	7.0	1.3	2.6	1.6	2.6	2.0	2.1	1.6	-0.1	0.9	1.6	0.7	-0.7	0.5	1.7	1.9
Impedance of leg (right)	1.9	9.4	17.3	2.8	3.3	3.7	4.2	3.1	3.1	2.5	2.7	2.7	3.0	2.4	2.8	2.6	3.4	3.1
Qualifications: O levels/GCSEs or equivalent	1.9	3.0	7.1	1.5	1.4	2.4	1.7	0.8	0.8	2.7	2.5	1.9	2.2	2.3	1.4	0.2	0.9	0.9
Ever depressed for a whole week	1.9	2.3	5.8	-1.6	-1.0	-2.2	-1.9	-0.1	-1.3	-1.1	-0.7	-1.1	-2.0	-1.8	-2.4	-0.7	-1.5	-1.4
Neuroticism (2016)	1.8	2.5	5.1	-2.1	-0.7	-1.9	-1.9	-0.4	-2.2	-1.3	-0.4	-1.7	-1.5	-1.3	-0.7	-1.3	-2.2	-2.1
Verbal and Numeric Reasoning (VNR)	1.7	4.0	10.3	2.7	0.2	1.7	1.6	-0.6	1.5	1.5	2.9	2.4	3.2	2.3	1.4	2.3	1.5	1.6
Ulcerative Colitis	1.7	2.4	4.8	0.3	1.2	1.5	1.8	2.1	1.6	1.9	1.0	1.3	1.8	2.2	1.4	0.6	1.8	1.6
Neuroticism	1.7	4.1	14.5	-3.8	0.4	-2.0	-1.5	1.8	-2.1	-1.2	-1.6	-2.2	-3.0	-1.6	-0.7	-1.3	-2.5	-2.2
Maternal smoking around birth	1.7	2.5	6.3	-1.8	-0.7	-1.7	-2.5	-1.1	-1.6	-0.7	-0.8	-1.3	-1.4	-1.3	-1.9	-1.3	-2.3	-1.7
Mouth/teeth dental problems	1.7	2.6	6.6	1.6	1.0	2.4	1.9	-0.1	2.6	2.0	0.2	1.5	1.2	0.3	-0.4	0.7	2.4	2.4
Loud music exposure frequency	1.7	1.8	5.1	0.1	1.8	0.7	1.7	2.3	1.6	0.4	-1.1	0.7	0.2	1.4	1.5	1.6	1.4	1.5
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	6.1	0.9	1.8	1.0	1.3	1.2	1.3	0.5	1.0	1.8	1.6	1.9	1.8	2.5	1.0	1.4
Medication: Ventolin 100micrograms inhaler	1.7	2.1	4.7	-1.9	-1.8	-1.3	-0.8	-2.1	-0.4	-1.6	-2.0	-1.7	-2.2	-1.6	-0.5	-0.7	-0.7	-0.6
Asthma (self-reported)	1.7	3.4	7.3	-2.6	-2.6	-2.2	-1.6	-1.2	-1.4	-0.9	-1.5	-1.9	-2.7	-1.8	-1.4	-1.5	-1.8	-1.6
Impedance of whole body	1.7	8.5	18.8	3.1	3.4	3.5	4.3	2.0	3.4	2.1	2.0	2.0	2.8	2.1	2.1	2.9	3.3	3.3
Crohns Disease (2012)	1.6	2.6	5.2	1.8	0.1	1.0	1.6	1.5	1.8	-0.1	2.0	2.2	2.2	1.2	0.7	2.3	1.6	1.9
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.7	7.5	1.5	1.6	2.7	2.7	0.8	2.4	1.8	1.8	1.8	1.8	1.4	1.5	1.2	2.2	2.4
Heart disease (mother)	1.6	1.9	5.0	-0.1	0.3	1.3	1.2	0.2	2.2	-0.0	-0.5	1.5	0.9	1.2	2.2	1.5	2.0	2.2
Alcohol drinker status: Previous	1.6	1.8	5.9	-0.8	-1.9	-1.1	-1.6	-0.4	-1.4	-0.6	-0.2	-0.9	-1.6	-1.2	-2.4	-1.4	-1.4	-1.4
Medication for hormone replacement therapy	1.5	1.6	3.9	-1.5	-0.3	-2.0	-0.4	0.1	-1.1	-1.6	1.6	-1.1	-1.0	-1.9	-1.5	-0.5	-1.6	-1.0
Had menopause	1.5	1.9	5.3	1.1	1.0	0.9	0.9	1.3	1.3	-0.6	0.6	1.7	1.4	1.7	2.3	2.0	1.3	1.4
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.5	6.7	1.8	1.5	2.6	2.6	0.2	2.5	1.6	1.8	2.1	2.0	1.0	0.9	1.0	2.2	2.4
Medication: Ramipril	1.5	2.0	6.4	-1.7	-1.5	-1.0	-2.5	-1.8	-0.6	0.0	-2.1	-1.0	-1.9	-0.7	-1.0	-1.5	-0.4	-0.6
Neuroticism score	1.5	3.2	7.1	-2.7	0.2	-1.9	-1.2	1.1	-2.2	-0.8	-1.3	-2.0	-2.2	-1.6	-0.9	-1.7	-2.5	-2.2
Alcohol drinker status: Never	1.5	1.7	8.6	1.1	2.9	1.4	1.1	-0.5	0.7	0.8	0.5	0.5	0.9	2.1	1.5	1.6	0.9	0.7
Alzheimer’s Disease (in father)	1.4	1.5	7.3	-2.7	-0.8	-0.9	-1.3	-1.1	-0.4	-1.1	-2.0	-0.6	-1.6	-1.1	0.6	-0.8	-0.3	-0.4
Respiratory disease	1.4	3.2	9.9	-2.9	-1.3	-2.4	-1.6	-0.2	-1.6	-0.9	-1.8	-2.1	-3.1	-1.0	-0.6	-1.1	-1.9	-1.6
Ever used hormone-replacement therapy (HRT)	1.4	1.8	5.2	-2.3	0.1	-1.7	-0.0	-0.7	-0.4	-1.0	-1.2	-1.4	-1.6	-2.0	-1.3	-2.1	-0.4	-0.5
Fed-up feelings	1.4	2.6	6.3	-2.0	0.2	-2.1	-0.8	1.6	-1.5	-0.9	-1.7	-2.1	-2.5	-1.6	-1.1	-0.8	-2.0	-1.6
Chronic bronchitis/emphysema (father)	1.4	1.6	4.7	-1.4	0.1	-1.5	-0.8	-0.4	-1.1	-1.4	-1.8	-1.2	-2.2	-1.3	-0.9	-1.3	-1.1	-1.1
Asthma	1.4	2.8	6.9	-2.4	-2.6	-1.8	-1.4	-1.2	-1.1	-0.8	-1.6	-1.6	-2.6	-1.4	-1.3	-1.2	-1.4	-1.3
Length of working week for main job	1.4	1.5	5.3	1.7	1.4	1.4	1.5	0.2	0.9	1.0	2.3	0.8	1.8	0.5	-0.0	-0.3	1.0	1.0
Comparative body size at age 10	1.4	3.9	10.0	-1.8	-1.6	-2.1	-3.2	-2.3	-1.6	-3.0	-1.6	-1.9	-2.0	-2.1	-1.2	-1.1	-1.4	-1.6
Age at last live birth	1.4	2.1	5.2	1.3	2.2	1.4	2.2	1.4	0.9	2.3	1.7	0.3	1.8	1.5	0.7	0.1	0.7	0.8
Ever smoked	1.4	2.5	5.7	-2.0	-1.0	-1.8	-1.0	-1.0	-1.5	-1.2	-0.9	-0.7	-1.9	-2.4	-2.1	-1.6	-1.8	-1.5
Schizophrenia (2018)	1.3	2.6	8.4	-1.8	-1.1	-2.2	-1.4	-1.9	-0.7	-2.6	-2.9	-1.6	-2.3	-0.5	0.6	-0.3	-0.5	-0.8
Major Depression (MDD)	1.3	1.6	4.6	-1.3	0.3	-1.3	-1.9	0.2	-2.2	-0.5	-0.5	-0.7	-1.3	-0.7	-0.0	-1.0	-2.0	-2.0
HbA1C	1.3	1.5	3.2	1.6	-0.9	1.2	0.2	-0.9	1.0	-0.4	1.8	1.7	1.8	1.1	0.6	1.5	0.9	1.1
Relative age of first facial hair	1.3	2.6	5.8	1.1	0.3	1.5	1.7	0.9	1.9	2.4	2.3	2.1	1.7	1.3	0.6	0.8	2.1	1.9
Vitamin and mineral supplements	1.3	1.7	4.7	1.8	1.7	1.5	1.5	0.6	1.1	2.2	0.7	0.8	1.2	1.6	-0.4	0.9	1.2	1.0
Average weekly fortified wine intake	1.3	1.5	4.9	1.5	1.5	0.9	2.2	1.7	1.0	1.8	1.1	0.3	0.8	1.3	0.2	0.5	0.6	0.9
Qualifications: None of the above	1.3	2.9	11.3	-1.7	-1.4	-2.1	-1.9	-1.9	-0.4	-2.5	-3.4	-1.4	-1.9	-1.5	-0.1	0.7	-0.4	-0.5
Illnesses of mother	1.3	1.7	5.9	-0.6	-0.3	-0.9	-1.5	-0.0	-2.2	-0.6	0.4	-0.8	-0.6	-0.9	-1.9	-0.6	-2.4	-2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	7.8	-2.8	-0.1	-1.4	-2.1	0.9	-2.1	-0.9	-0.4	-0.1	-1.1	-0.4	-0.3	-0.2	-2.0	-1.9
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	4.0	-1.8	-1.1	-1.5	-1.6	-0.7	-1.6	-0.9	-0.5	-1.7	-1.6	-2.0	-1.1	-1.3	-1.9	-1.6
Birth weight	1.3	2.8	6.5	0.5	-2.2	-1.8	-1.7	-0.6	-2.5	-1.4	0.8	-1.1	-0.4	-1.9	-2.0	-1.5	-2.2	-2.5
Alzheimer’s Disease (including proxy)	1.2	1.8	4.9	-2.2	-0.2	-1.2	-1.0	-0.5	-0.9	-0.2	-1.2	-1.6	-1.7	-1.9	-1.3	-2.0	-0.7	-0.9
Ulcerative Colitis (UC)	1.2	2.2	6.0	0.8	0.6	1.1	2.1	2.4	1.2	1.3	1.8	1.3	1.6	2.1	1.5	0.8	1.5	1.2
Coronary Artery Disease (CAD)	1.2	1.4	3.1	-0.0	0.7	1.2	1.2	1.5	1.4	1.6	0.2	1.2	1.2	1.8	0.6	0.6	1.3	1.4
Frequency of depressed mood in last 2 weeks	1.2	1.7	4.7	-0.7	-0.9	-1.5	-0.5	1.9	-2.1	-1.3	-0.3	-0.9	-0.7	-0.5	-1.0	-0.4	-2.2	-2.1
Hair/balding pattern: Pattern 2	1.2	1.5	3.9	-0.0	0.1	-0.6	-0.6	0.6	-2.0	-0.1	1.7	-0.4	0.2	-0.9	-1.6	-1.9	-2.0	-1.9
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	5.1	1.4	0.5	0.8	1.8	1.1	1.3	0.1	-0.5	0.6	1.3	1.0	0.8	2.2	1.4	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.7	13.2	0.2	-0.2	-1.2	-1.1	0.6	-2.6	-0.4	2.0	-1.6	-0.3	-2.4	-3.6	-2.9	-2.4	-2.5
Peak expiratory flow (PEF)	1.2	2.9	10.6	-1.0	0.1	-1.9	-0.6	0.3	-1.6	-1.6	0.3	-1.6	-1.8	-2.8	-3.3	-1.7	-1.8	-1.6
Migraine (self-reported)	1.2	1.5	4.6	-1.5	-0.4	-1.5	-1.0	0.1	-1.4	-2.1	-0.7	-1.0	-1.4	-1.1	-0.9	0.3	-1.8	-1.3
Had major operations	1.2	1.5	3.8	-1.6	-1.0	-1.7	-0.7	-0.0	-1.3	-2.0	-1.3	-0.7	-1.3	-1.2	-0.2	-0.6	-1.4	-1.3
Mineral and other dietary supplements	1.2	1.7	3.6	-0.4	-1.2	-0.5	-1.5	-0.4	-1.6	1.5	0.5	-1.3	-1.3	-0.9	-1.9	-1.9	-1.5	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.6	5.1	2.2	1.9	1.8	1.1	0.8	1.6	2.3	1.7	1.1	2.0	1.0	-1.3	-0.2	1.9	1.6
Tinnitus: Yes, now most or all of the time	1.2	1.3	5.2	-1.1	0.3	-0.9	0.3	0.5	-0.2	-1.5	-1.6	-1.4	-1.3	-1.6	-2.3	-0.9	-0.7	-0.4
Irritability	1.2	2.0	5.0	-1.8	-0.3	-1.8	-2.2	-1.2	-1.8	-0.6	-1.1	-1.2	-1.9	-0.8	0.3	-0.4	-2.0	-1.8
Medication: Co-codamol	1.1	1.3	6.1	-2.5	-0.8	-0.8	-1.3	0.5	0.0	-1.3	-1.8	-0.2	-1.4	-1.5	-0.6	0.2	-0.1	0.1
Multivitamins +/- minerals	1.1	1.4	3.4	-1.8	-1.5	-1.5	-1.6	-1.4	-1.3	-0.6	-0.4	-0.5	-1.0	-1.2	0.5	-1.0	-1.2	-1.3
High blood pressure (mother)	1.1	1.5	3.5	1.8	0.8	0.6	1.3	1.4	1.1	1.2	0.9	1.0	1.2	1.1	1.9	0.8	1.4	1.1
Forced expiratory volume in 1-second (FEV1)	1.1	3.6	13.3	-0.3	0.1	-1.6	-1.1	0.1	-2.6	-1.1	1.9	-1.3	-0.5	-2.4	-3.6	-2.2	-2.5	-2.5
Gout (self-reported)	1.1	1.6	5.8	0.2	0.8	1.2	1.6	-0.2	2.4	0.4	-1.2	0.6	0.3	-0.0	0.4	-0.4	2.4	2.2
Qualifications: College or University degree	1.1	3.4	11.6	2.2	1.2	1.1	1.9	2.1	0.7	1.2	3.4	1.8	2.5	2.2	1.6	1.7	0.9	1.0
Leg pain on walking	1.1	1.3	6.9	-1.2	-1.1	-0.5	-0.3	-1.7	0.3	-1.8	-2.6	-0.4	-1.1	-1.3	-0.6	0.4	0.2	0.2
Osteoarthritis (self-reported)	1.1	1.5	3.7	1.8	0.5	1.1	1.9	1.1	1.1	-1.6	0.3	0.8	1.4	0.8	0.6	1.7	1.1	1.1
Basal cell carcinoma (self-reported)	1.1	1.3	2.9	-1.2	-0.5	-1.1	-1.4	0.3	-0.9	0.0	-1.4	-1.6	-1.7	-0.7	-1.4	-1.4	-1.1	-1.0
Depression (Nagel 2018)	1.0	1.5	16.4	0.3	0.2	-0.4	0.5	4.1	-1.3	-0.6	0.6	0.0	0.1	0.5	-0.1	0.5	-1.2	-1.3
Irritable Bowel Disease (IBD)	1.0	2.3	6.8	1.1	0.4	1.4	2.2	2.6	1.4	0.5	1.7	1.5	1.8	1.8	0.8	1.0	1.5	1.4
Angina	1.0	1.3	4.7	-0.6	0.4	-0.6	-1.1	-0.7	-2.2	-0.2	-0.6	-1.2	-0.4	-0.1	-0.5	-0.9	-2.0	-2.2
Taking other prescription medications	1.0	1.6	4.8	-1.6	-0.5	-1.7	-0.1	-0.3	-0.4	-1.8	-2.2	-1.7	-1.8	-1.5	-1.0	-0.6	-0.6	-0.6
Qualifications: CSEs or equivalent	1.0	1.3	3.2	-1.5	0.4	-1.0	-0.5	-0.1	-0.4	1.0	-1.3	-1.8	-1.1	-1.2	-1.6	-1.8	-0.9	-0.6
Hair/balding pattern: Pattern 3	1.0	1.5	5.3	-2.3	-1.9	-0.3	-2.0	-1.2	-0.2	0.2	-1.8	-1.1	-1.6	-0.6	-0.7	-0.7	-0.1	-0.3
Happiness	1.0	1.2	3.7	-1.3	-0.5	-1.9	-1.3	-0.2	-1.5	-0.7	-0.6	-0.7	-1.2	-0.2	0.0	-0.6	-1.6	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	5.6	-2.4	1.4	-1.0	-1.3	0.8	-1.5	0.8	0.2	0.2	-0.7	0.3	-0.3	-0.5	-1.7	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	4.2	-0.2	1.5	0.5	1.4	1.2	1.1	1.3	0.2	0.8	0.9	2.0	0.9	0.6	1.1	1.1
Emphysema/chronic bronchitis	1.0	1.1	3.8	-1.1	-1.3	-0.7	-0.4	1.0	-0.5	-1.1	-1.9	-0.8	-1.5	-1.1	-1.1	0.0	-1.3	-0.5
Angina (self-reported)	1.0	1.3	4.7	-0.6	0.2	-0.6	-1.1	-0.6	-2.2	-0.3	-0.6	-1.2	-0.5	-0.2	-0.6	-1.0	-2.0	-2.2
Commuting to job workplace: Car/motor vehicle	1.0	1.1	3.9	-2.0	0.0	-1.8	-1.0	-1.0	-1.0	-1.6	1.2	0.2	-1.0	-0.5	-0.3	-0.1	-0.8	-0.8
Handedness (chirality/laterality): Left-handed	1.0	1.2	3.1	1.3	0.4	0.9	0.1	0.2	1.4	1.6	-1.1	0.9	0.4	1.8	0.8	1.3	1.5	1.3
Myopia	1.0	1.4	5.2	-2.0	-0.0	-1.1	-0.8	-1.2	-1.1	-0.5	-0.1	-1.5	-1.4	-1.0	-0.3	-2.3	-0.6	-1.3
Cardiovascular Disease	0.9	2.9	7.0	-0.1	1.4	1.8	1.6	1.7	2.3	2.6	-1.6	1.1	0.3	2.1	1.0	-0.2	2.6	2.1
Illnesses of siblings	0.9	1.2	4.0	2.0	-0.1	1.4	0.8	0.9	-0.0	1.0	1.9	1.1	1.8	0.9	-0.2	0.5	-0.1	0.1
Hip circumference	0.9	3.8	7.1	-2.7	-1.4	-2.1	-2.1	0.3	-2.2	-2.3	-1.8	-1.8	-2.3	-1.4	-1.6	-1.7	-2.0	-2.2
Depression (self-reported)	0.9	1.1	6.6	-2.6	-0.1	-1.0	-0.5	0.4	-0.6	-1.1	-0.9	-0.7	-1.1	-1.1	-0.6	-1.3	-0.8	-0.6
Shortness of breath walking on level ground	0.9	1.1	4.1	-2.0	-0.4	-1.1	-0.4	-0.1	-0.7	-0.5	-1.4	-0.9	-1.2	-1.1	-1.2	-1.3	-1.0	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	9.4	-0.2	3.1	0.7	1.2	1.3	0.5	1.1	-0.2	0.6	0.1	0.9	0.7	0.4	0.4	0.5
Medication: Bendroflumethiazide	0.9	1.4	6.1	0.8	1.4	0.5	0.2	0.0	0.8	1.2	0.5	1.3	1.1	2.5	2.0	1.1	1.1	0.8
Medication: Lisinopril	0.9	1.1	3.9	0.8	0.6	1.3	0.5	0.3	0.8	1.2	0.3	1.2	1.4	2.0	1.3	1.3	0.6	0.8
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	3.2	1.1	1.6	1.1	1.2	0.9	1.1	0.7	0.1	1.0	1.2	1.2	0.4	1.8	0.8	1.0
Neuroticism (Nagel 2018)	0.8	1.8	4.0	-1.8	0.9	-1.4	-0.3	2.0	-1.8	0.1	0.5	-1.6	-1.2	-0.7	-1.0	-0.8	-2.0	-1.8
Allergy or Eczema	0.8	2.0	5.4	0.4	0.6	0.3	1.2	1.5	0.7	1.6	2.0	1.9	1.4	1.9	2.3	1.6	0.6	0.8
Type 2 Diabetes (T2D) (2018)	0.8	1.5	5.4	2.3	-0.7	1.8	0.1	-0.7	1.5	1.6	0.2	1.1	1.0	0.1	-0.2	-0.5	1.9	1.5
Medication: Metformin	0.8	1.2	3.0	1.7	0.2	1.2	0.4	0.1	1.4	1.6	1.0	0.8	1.0	0.0	-0.7	-0.7	1.6	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	7.0	-0.9	0.3	-0.8	0.3	2.6	-1.2	-0.8	-0.1	-0.5	-0.9	0.7	-0.0	0.2	-1.5	-1.2
Heart attack	0.8	1.0	5.6	-0.2	1.4	1.2	0.3	1.1	0.7	2.4	-0.5	0.5	-0.2	1.4	0.6	0.5	0.8	0.6
Time employed in main current job	0.8	0.9	4.0	-2.0	1.3	-0.7	-1.4	1.0	-0.5	-0.7	-1.4	-0.2	-0.8	-0.6	0.4	-0.3	-0.6	-0.4
Medication: Lansoprazole	0.8	0.9	2.4	-0.9	1.6	0.1	0.5	1.1	1.4	0.8	-1.4	0.3	0.1	0.7	0.2	0.7	1.0	1.3
Prospective memory result	0.8	1.0	4.2	-0.2	2.1	-1.0	-0.1	-0.8	0.2	-1.4	-1.9	-0.7	-1.5	-0.3	0.3	0.6	0.1	0.1
Hair/balding pattern: Pattern 4	0.8	2.0	6.9	-2.0	0.3	-2.2	-0.1	-0.3	-1.3	-2.6	-0.2	-1.9	-1.8	-1.5	-0.0	-0.3	-1.4	-1.2
Blood clot in the leg (DVT)	0.8	1.0	3.1	1.4	1.1	0.9	1.1	0.5	1.2	0.3	-0.2	0.9	1.1	1.0	0.4	1.8	0.9	1.1
Headache pain in last month	0.8	1.4	4.9	-1.3	-1.4	-0.8	-1.2	-0.6	-1.4	-2.2	0.3	-0.3	-0.3	-1.6	-1.2	-0.3	-1.5	-1.2
Chronic bronchitis/emphysema (mother)	0.8	1.0	3.2	-1.5	-1.4	-1.1	-1.6	-1.0	-0.7	-1.8	-0.4	-0.0	-0.6	0.2	0.6	0.2	-0.6	-0.6
Number of full brothers	0.8	0.9	3.9	-0.3	-0.9	-0.9	0.0	-1.2	-0.2	-2.0	-0.5	-1.1	-1.3	-1.4	-1.2	-0.0	-0.6	-0.3
Medication for pain relief, constipation, heartburn	0.8	1.4	6.6	2.6	1.1	0.9	1.4	0.9	0.2	1.3	2.2	0.4	1.2	0.5	0.0	0.2	0.5	0.3
Osteoporosis (self-reported)	0.8	1.0	2.6	-0.5	0.7	-0.5	0.5	1.6	-1.0	-1.0	-1.2	-0.7	-0.4	0.5	1.3	1.2	-1.5	-0.9
Illnesses of father: None of the above (group 1)	0.8	1.0	5.4	0.9	-1.6	0.4	0.6	0.1	-0.3	-0.7	1.2	-0.3	0.6	-1.4	-2.3	-0.7	-0.6	-0.3
Diastolic blood pressure, automated reading	0.8	2.4	7.7	0.2	2.2	1.0	1.7	2.8	1.5	1.8	1.0	0.9	0.4	1.4	1.9	-0.1	2.0	1.4
Rheumatoid Arthritis	0.7	0.9	3.0	1.3	-0.1	1.2	1.7	0.7	1.6	0.5	0.0	0.0	0.5	-0.3	0.1	-0.2	1.4	1.5
Hearing difficulty/problems with background noise	0.7	1.1	5.9	0.3	1.4	1.2	2.4	1.6	0.8	1.0	1.3	0.2	1.0	-0.2	-0.2	0.4	0.4	0.5
Noisy workplace	0.7	0.9	2.9	-1.1	-1.5	-0.4	-0.2	-0.4	-0.3	-1.3	-1.7	-0.7	-1.1	-1.4	-0.7	-0.0	-0.6	-0.4
Health satisfaction	0.7	0.9	2.7	-1.4	-0.5	-1.7	0.1	0.7	-0.9	-0.5	-0.6	-0.6	-1.1	-0.3	-0.4	-1.6	-1.1	-1.0
Medication: Blood pressure	0.7	1.2	2.7	0.9	0.5	1.2	1.0	0.4	1.4	1.5	-0.2	1.2	0.7	1.6	0.6	0.4	1.6	1.3
Pulse rate, automated reading	0.7	2.1	5.6	-2.4	-1.6	-0.9	-1.8	0.4	-1.8	-0.4	-1.1	-1.4	-1.8	-0.5	1.0	-1.6	-1.6	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.5	-0.2	1.4	-0.8	1.3	-0.4	1.1	-0.1	-0.7	0.2	-0.2	0.8	1.6	1.1	0.8	1.0
Illnesses of father: Heart disease	0.7	1.0	4.0	-0.4	1.8	-0.2	0.3	-0.3	0.7	0.4	0.6	0.7	0.6	1.8	2.0	1.2	1.1	0.7
Illnesses of siblings: Diabetes	0.7	0.8	3.3	-0.6	0.4	-0.4	0.4	-1.8	0.9	-0.6	-1.8	0.2	-0.6	0.4	1.1	0.8	0.9	0.9
Medication for cholesterol	0.7	1.1	5.9	2.4	0.1	1.1	1.2	1.3	0.5	-0.1	0.7	1.0	1.3	0.6	0.5	1.1	0.8	0.5
Miserableness	0.7	1.3	9.9	-0.8	1.7	0.4	1.7	3.1	0.5	0.7	0.9	0.3	0.1	-0.2	0.5	-0.1	0.4	0.5
Supplements: Fish oil (including cod liver oil)	0.7	0.9	3.6	0.5	1.4	-0.1	0.9	0.2	0.8	-1.3	-0.7	0.4	0.8	0.7	1.9	1.6	0.7	0.8
Risk taking	0.7	1.1	4.7	-0.2	-1.1	-0.6	-0.5	-0.6	-0.7	0.2	0.3	-1.3	-0.4	-1.4	-2.1	-2.2	-0.5	-0.7
Heart attack/myocardial infarction (self-reported)	0.7	0.9	5.0	-0.4	1.2	1.1	0.2	1.2	0.6	2.2	-0.6	0.4	-0.4	1.4	0.6	0.4	0.7	0.5
Bipolar Disorder (2018)	0.6	0.9	6.5	0.7	0.8	0.3	0.2	0.3	-0.7	1.6	2.5	0.7	1.3	0.8	0.2	-0.3	-0.2	-0.6
Reaction Time	0.6	1.1	2.6	1.2	0.4	1.6	0.1	-1.2	1.4	0.9	-1.3	1.0	0.6	0.6	0.3	1.2	1.3	1.3
Chronotype (morning person)	0.6	1.4	6.1	-0.9	1.7	-0.9	-0.1	-0.2	-1.1	0.8	-0.4	-1.1	-1.0	-0.8	-1.9	-2.5	-0.8	-1.3
Serious illness, injury or assault to yourself	0.6	0.7	4.6	0.2	0.2	1.3	0.9	0.3	0.8	2.1	0.5	0.8	0.3	0.2	-0.6	-0.9	0.5	0.7
Hayfever, allergic rhinitis or eczema	0.6	1.2	4.1	0.2	-0.9	0.2	0.3	0.6	0.3	1.4	1.8	1.6	1.2	1.6	2.0	1.0	0.4	0.4
Medication: Atenolol	0.6	0.7	2.6	-1.0	1.2	0.1	0.9	1.4	-0.3	1.6	-0.4	-0.2	-0.0	1.5	0.6	-0.3	-0.4	-0.4
Nervous feelings	0.6	1.2	2.9	-1.4	0.5	-1.3	-0.6	0.7	-1.6	-0.6	0.5	-1.2	-0.5	-1.1	-0.4	-1.4	-1.7	-1.6
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	4.4	-0.6	0.3	-0.2	0.2	0.7	-0.7	1.5	2.1	0.4	0.6	1.0	0.8	0.6	-0.1	-0.7
Worrier / anxious feelings	0.6	1.2	3.3	-0.8	0.8	-1.8	0.9	0.3	-0.4	-1.1	-1.3	-1.8	-1.2	-1.4	-1.1	-0.4	-1.1	-0.6
Leg fat percentage (right)	0.6	2.1	10.6	-0.3	1.4	1.7	1.5	3.3	1.7	0.6	-0.5	1.1	0.1	0.9	0.9	0.7	1.9	1.6
Wheeze or whistling in the chest in last year	0.6	1.0	3.4	-1.8	0.1	-0.7	0.2	0.8	0.3	-1.7	-1.8	-0.3	-1.7	-0.2	0.9	0.8	-0.3	0.3
Age at first live birth	0.6	1.1	5.1	0.8	2.2	0.3	1.0	1.5	-0.2	2.1	0.7	0.1	0.9	0.8	0.6	-0.5	0.1	-0.2
Mean time to correctly identify matches	0.6	1.2	2.6	1.6	0.6	1.6	0.6	-0.8	1.5	0.4	-1.3	0.8	0.8	0.4	-0.2	1.1	1.5	1.4
Alcohol intake frequency.	0.6	1.4	5.4	-1.2	0.1	-1.1	-1.1	-1.1	-1.0	0.2	-1.6	-1.6	-2.3	-0.3	-1.1	-0.2	-1.2	-1.1
Overall health rating	0.6	1.3	4.4	-2.1	-1.0	-1.3	-1.0	0.1	-1.0	-0.7	-1.4	-1.3	-1.1	-0.4	0.4	-1.6	-1.0	-1.1
Knee pain experienced in last month	0.6	1.0	9.4	-0.2	-1.1	-0.7	-0.3	-0.3	-0.5	-3.1	0.0	-0.0	0.3	-1.0	-1.1	0.4	-0.6	-0.4
Hypertension (Self-reported)	0.6	1.7	5.5	-0.6	1.8	1.0	0.9	0.6	1.6	2.4	-1.6	0.7	-0.2	1.4	0.8	-0.5	1.9	1.4
Average weekly champagne plus white wine intake	0.6	0.8	4.5	0.6	-1.5	-0.8	-1.0	0.3	-0.6	-2.1	-0.6	-0.7	0.2	-0.8	-0.2	0.2	-0.7	-0.6
Mother’s age at death	0.6	0.8	4.0	0.1	-1.3	-0.8	0.2	-0.5	-0.4	-0.3	-0.9	-0.6	-0.6	-1.6	-2.0	-0.8	-0.3	-0.5
High cholesterol (Self-reported)	0.6	1.1	4.4	0.7	0.7	0.6	0.4	0.1	1.1	0.7	-0.0	1.3	1.0	2.1	1.4	1.1	1.3	1.1
Leg fat percentage (left)	0.6	2.2	8.0	-0.2	1.1	1.8	1.5	2.8	2.1	0.4	-1.0	1.0	0.0	0.9	0.7	0.9	2.2	2.0
Unable to work because of sickness or disability	0.6	0.8	3.7	-1.4	0.8	0.1	0.3	0.8	0.6	-0.8	-0.9	0.6	-0.2	1.3	0.9	1.9	0.5	0.6
Vascular/heart problems diagnosed by doctor	0.6	1.6	7.6	-0.0	-1.6	-1.2	-1.0	-0.2	-1.6	-2.8	0.8	-0.7	-0.3	-1.5	-0.7	0.4	-1.8	-1.4
Depressed Affect (Nagel 2018)	0.5	1.1	7.4	-1.7	1.3	-0.6	0.4	2.7	-0.8	0.4	-0.2	-0.8	-1.1	-0.4	-0.4	-0.2	-1.0	-0.9
Worry (Nagel 2018)	0.5	1.0	2.8	-1.4	0.2	-1.0	-0.4	1.1	-1.5	-0.1	0.2	-1.2	-0.7	-0.5	-0.6	-0.6	-1.7	-1.5
Crohns Disease (2017)	0.5	1.2	2.3	1.2	-0.4	1.1	1.1	1.0	1.1	-0.8	1.1	1.5	1.5	0.9	0.0	1.2	1.1	1.1
Breast Cancer	0.5	1.1	3.8	-1.9	-1.0	-1.2	-1.6	-1.3	-0.8	-0.8	0.5	-0.5	-1.5	-0.3	0.8	-0.2	-0.8	-0.6
Ovarian Cancer	0.5	0.7	2.1	0.1	0.3	-0.5	-1.5	-0.8	0.2	-1.4	-1.3	0.7	-0.5	0.9	1.0	0.9	0.1	0.3
LDL Cholesterol	0.5	0.9	2.9	-0.6	-1.4	-0.4	-1.0	-1.7	0.4	-1.5	-1.5	0.1	-0.7	-0.1	0.0	1.0	0.3	0.4
Schizophrenia (2014)	0.5	1.0	5.3	-1.0	-0.2	-1.1	-0.3	-1.4	0.3	-1.7	-2.3	-0.6	-1.3	-0.1	0.7	0.5	0.5	0.2
Triglycerides	0.5	0.8	2.7	0.7	1.7	0.9	0.3	1.1	0.4	0.7	-0.1	1.1	0.7	1.2	0.5	1.5	0.2	0.6
Systolic Blood Pressure	0.5	2.4	7.7	-0.0	0.6	1.7	1.5	2.2	2.3	1.9	-1.4	0.6	-0.6	1.3	0.5	-0.5	2.8	2.1
Number of treatments/medications taken	0.5	0.9	2.9	-1.4	-1.0	-1.2	-0.4	-0.1	-0.3	-1.1	-1.7	-0.9	-1.4	-1.1	-0.4	-0.7	-0.4	-0.4
Ever had hysterectomy (womb removed)	0.5	0.6	3.3	-0.1	-0.4	-1.1	0.6	0.9	0.5	-1.8	0.3	-0.1	-0.4	-1.0	-0.2	1.1	0.1	0.5
Systolic blood pressure, automated reading	0.5	1.3	5.8	-0.5	0.6	0.4	1.1	1.3	1.9	-0.3	-1.0	0.3	-0.8	0.5	1.3	-0.1	2.4	1.9
Diabetes (mother)	0.5	0.7	3.4	-1.9	0.1	-0.7	-1.1	-0.1	-0.2	-1.0	-0.7	-0.7	-1.3	-0.9	-0.0	-0.6	-0.0	-0.2
Severe depression (siblings)	0.5	0.5	1.9	-1.4	-1.0	-0.4	-0.9	0.2	-0.6	0.2	0.1	-0.1	-1.1	0.1	0.0	-0.6	-1.2	-0.5
High blood pressure	0.5	1.5	6.2	-0.4	1.3	0.9	0.8	0.2	1.6	2.5	-1.2	0.6	-0.1	1.4	0.6	-0.6	1.9	1.4
Trunk fat mass	0.5	2.1	4.5	-1.9	-0.7	-1.3	-1.3	1.4	-1.2	-2.1	-1.7	-1.1	-2.1	-1.5	-1.6	-1.1	-1.0	-1.3
Number of incorrect matches in round	0.5	0.8	2.0	1.4	0.6	1.3	1.4	1.0	0.9	0.7	-1.2	0.7	0.2	0.6	0.0	0.3	1.0	0.8
Past tobacco smoking	0.5	1.0	2.1	1.2	0.3	1.4	0.9	0.1	1.0	1.1	0.5	0.2	0.9	1.4	1.4	0.6	1.2	1.0
Impedance of arm (right)	0.5	2.2	7.0	1.8	2.3	1.5	2.7	0.8	1.7	1.0	0.3	0.2	1.2	0.6	1.1	1.1	1.7	1.6
Father’s age at death	0.5	0.7	2.6	1.3	0.7	1.0	0.9	1.6	0.8	0.2	-0.4	0.3	0.6	0.7	-0.3	0.9	0.7	0.8
Impedance of arm (left)	0.5	2.5	7.9	1.9	2.4	1.7	2.8	1.0	1.6	1.1	1.1	0.4	1.4	1.0	1.0	1.5	1.6	1.4
Arm fat mass (right)	0.5	1.9	4.8	-1.9	-0.7	-1.2	-1.1	1.2	-0.9	-1.5	-2.2	-1.2	-2.1	-1.2	-1.3	-1.5	-0.8	-1.0
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.0	1.4	-1.0	0.4	-0.3	-0.7	0.9	-0.5	0.1	1.2	0.4	0.0	0.6	1.0	0.5	1.0
Exposure to tobacco smoke outside home	0.5	0.6	3.0	-0.6	-0.4	-0.5	0.0	-0.5	-0.5	-0.6	-0.6	-0.8	-1.3	-1.7	-1.1	-0.4	-0.8	-0.5
Number of children fathered	0.5	0.5	2.3	-1.0	-0.8	-0.4	-0.6	0.9	-0.7	-0.9	0.5	0.5	-0.3	-0.4	-1.5	-0.1	-0.7	-0.6
Medication: Allopurinol	0.5	0.6	3.7	-0.1	0.0	0.2	0.6	-0.7	1.1	-0.4	-1.9	-0.1	-0.3	-0.6	-0.7	-0.5	1.2	0.9
Medication: Seretide 50 evohaler	0.5	0.5	2.0	-0.6	0.8	-0.4	0.6	1.4	-0.4	-0.5	-1.3	-1.1	-0.8	0.0	0.1	0.2	-0.6	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.1	-0.3	-0.1	0.3	0.4	1.1	-0.6	-0.1	-0.3	-1.0	-1.0	-1.0	-0.6	-1.5	-0.8	-0.6
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.2	-0.6	-0.1	-0.9	-0.8	-1.2	-0.7	0.1	0.3	-0.5	-0.5	-1.2	-0.3	-1.5	-0.7	-0.7
Medication: Gliclazide	0.5	0.5	1.5	0.6	-0.1	0.9	0.1	-0.3	0.9	0.6	-0.3	1.0	0.5	0.9	0.1	1.2	0.9	0.9
Guilty feelings	0.5	0.7	2.9	0.3	1.7	0.2	0.1	0.9	-0.8	1.5	1.0	-0.6	0.1	0.1	-0.5	-0.9	-0.9	-0.8
Medication: Paracetamol	0.5	0.7	3.6	-1.6	-1.2	-0.3	-0.4	-0.5	0.5	-1.9	-1.0	0.2	0.0	-0.6	0.3	0.9	0.1	0.6
Fractured/broken bones in last 5 years	0.5	0.7	2.4	-1.6	-1.3	-0.2	-1.3	0.2	-1.0	-0.3	-0.4	-0.1	-0.6	-0.1	-0.5	-0.3	-1.3	-0.8
Supplements: Calcium	0.5	0.5	4.5	0.0	0.7	-0.3	0.3	0.6	0.3	0.4	0.0	0.6	0.5	1.0	2.1	0.4	0.3	0.3
Intelligence (Savage-Jansen 2018)	0.4	1.3	7.1	2.7	-1.0	0.6	0.7	-1.5	0.0	0.6	1.9	0.4	1.9	0.4	0.2	0.5	0.3	0.0
Alzheimer’s Disease (in mother)	0.4	0.5	2.2	-0.4	0.6	-0.1	-0.4	-0.4	-0.3	0.9	0.1	-0.6	-0.5	-0.8	-1.4	-1.5	0.0	-0.3
Age at First Birth	0.4	0.6	3.2	0.1	-0.1	0.0	-0.7	-1.8	-0.3	1.2	-0.2	-1.0	-0.7	-0.5	-0.6	-1.1	0.1	-0.4
Bipolar Disorder (2011)	0.4	0.4	3.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.0	0.0	-1.2	0.0	-1.9
Body Mass Index (BMI) (2010)	0.4	0.5	3.3	1.0	0.4	0.8	0.4	1.8	0.2	0.3	1.1	0.8	0.6	0.1	-0.2	-0.0	0.1	0.2
Mean Putamen Volume	0.4	0.5	3.6	-0.1	-0.3	0.2	-0.5	0.6	-0.4	0.6	-0.2	-0.2	-0.3	-0.5	-1.4	-1.9	-0.2	-0.4
HDL Cholesterol	0.4	0.6	1.5	0.9	-1.1	1.2	0.1	-0.8	1.0	-0.4	0.2	0.3	0.8	0.2	-0.1	0.8	1.2	0.9
Average weekly spirits intake	0.4	0.5	2.4	-1.5	-1.5	-0.6	-0.7	-0.4	-0.4	-0.9	-0.5	0.3	-0.3	0.2	-0.3	0.5	-0.8	-0.3
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	3.0	-0.6	1.3	0.1	0.5	1.7	-0.2	-0.0	-1.0	-0.6	-0.7	-0.3	0.4	0.0	-0.2	-0.2
Supplements: Zinc	0.4	0.4	1.2	-0.8	0.1	-1.0	-1.0	-0.0	-0.8	0.2	-1.1	-0.2	-0.5	-0.1	0.1	-0.3	-0.4	-0.8
Diabetes (father)	0.4	0.5	1.8	-0.9	0.5	-0.5	-0.4	0.3	-0.7	0.4	-1.4	-1.0	-1.0	0.5	0.3	-0.9	-0.3	-0.7
Current tobacco smoking	0.4	0.7	2.9	0.5	-1.7	0.5	-0.7	-1.5	-0.1	0.9	0.3	0.3	-0.2	-0.9	-1.2	-0.9	-0.2	-0.1
Relative age voice broke	0.4	0.6	3.6	-0.4	0.2	0.4	0.1	0.0	-0.1	1.8	1.9	0.7	0.3	0.6	-0.4	-0.4	-0.0	-0.1
Age when periods started (menarche)	0.4	1.0	3.9	0.5	1.4	-0.5	0.5	-1.2	-0.2	0.3	0.8	-0.9	-0.4	-2.0	-1.9	-1.3	-0.4	-0.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	2.4	-0.2	1.0	-0.7	1.4	1.5	0.5	0.0	0.3	-0.2	-0.1	-0.3	0.2	-0.5	0.7	0.3
Medication: Levothyroxine sodium	0.4	0.7	3.1	0.6	-0.5	1.3	1.8	-0.8	0.7	0.5	0.9	0.5	0.9	0.3	-1.4	0.3	0.3	0.6
Financial difficulties in last 2 years	0.4	0.5	1.3	0.9	-0.1	0.8	0.7	0.9	0.6	0.9	0.7	0.4	0.8	1.1	-0.2	0.4	0.6	0.5
Pain all over the body in last month	0.4	0.4	2.3	-0.3	-0.3	-0.1	-0.5	-0.9	0.1	-0.7	-1.5	0.0	-0.2	0.4	0.6	1.2	-0.1	0.1
Diabetes (self-reported)	0.4	0.6	1.9	1.4	-0.4	0.8	-0.1	-0.7	1.3	0.8	-0.4	0.5	0.5	0.0	-0.1	-0.3	1.3	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.9	-0.4	1.1	-0.0	0.6	1.7	-0.0	0.2	-1.1	0.1	-0.4	1.1	0.6	0.9	-0.4	-0.1
Pulse wave Arterial Stiffness index	0.4	0.5	2.4	0.5	-1.6	-0.9	-0.9	-0.2	-1.1	-0.8	0.6	0.0	0.3	0.3	0.1	-0.2	-0.4	-1.0
Medication: Paracetamol	0.4	0.7	3.3	-1.6	0.1	-0.5	0.0	0.1	0.5	-1.8	-1.1	-0.0	-0.0	-0.3	0.8	1.4	0.1	0.5
High blood pressure (siblings)	0.4	0.5	2.7	-1.6	0.2	-0.6	-0.1	0.6	0.5	0.0	-1.1	-0.4	-1.5	-0.4	-0.6	0.1	0.3	0.4
Worry too long after embarrassment	0.4	0.7	2.1	-0.7	0.5	-0.4	0.9	0.7	-0.9	0.7	1.1	-0.7	0.3	-0.4	-1.0	-0.9	-1.4	-1.1
Eye problems/disorders: None of the above	0.4	0.4	2.1	-0.7	-0.8	0.1	-1.4	-1.0	-0.3	0.8	0.5	0.2	-0.2	-0.4	-1.0	-0.3	-0.2	-0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.6	0.3	-0.6	-0.2	-0.1	0.4	-0.1	-1.2	0.2	1.1	0.7	0.8	1.3	1.2	0.1	0.1
Suffer from ‘nerves’	0.4	0.6	2.0	-0.1	1.1	0.3	0.6	1.4	-0.3	1.0	1.0	0.0	0.8	1.3	0.6	0.2	-0.5	-0.2
Smoking status: Previous	0.4	0.7	1.8	-1.1	0.2	-1.2	-0.6	0.5	-0.4	-1.2	-0.7	-0.1	-0.7	-1.4	-1.3	-0.1	-0.6	-0.4
Mood swings	0.4	0.7	4.9	-1.2	1.2	-0.4	0.8	2.2	-0.4	0.2	-0.5	-0.5	-0.8	0.2	-0.0	0.1	-0.7	-0.4
Loneliness, isolation	0.4	0.5	2.2	-0.6	0.5	-0.0	0.0	0.3	-0.8	1.2	1.0	0.3	0.3	1.5	0.8	-0.3	-0.8	-0.7
Long-standing illness, disability or infirmity	0.4	0.7	2.0	-1.1	-0.4	-0.4	0.0	0.3	-0.2	0.4	-1.0	-1.2	-1.2	-1.3	-0.8	-1.4	-0.3	-0.4
Diabetes diagnosed by doctor	0.4	0.6	2.2	1.5	-0.5	0.7	0.2	-0.2	1.0	1.2	0.1	0.5	0.8	0.1	-0.6	-0.7	1.2	0.9
Back pain experienced in last month	0.4	0.5	1.7	-0.8	1.3	0.4	0.4	-0.1	1.1	0.5	-0.8	0.0	-0.2	-0.4	-0.3	-0.7	1.2	1.0
Arm fat mass (left)	0.4	1.8	4.2	-1.9	-0.7	-1.3	-1.1	1.4	-0.9	-1.6	-1.8	-1.2	-2.0	-1.2	-1.2	-1.3	-0.8	-1.0
Hearing aid user	0.4	0.4	1.0	0.5	0.9	0.6	0.5	-0.4	1.0	0.0	0.4	0.3	0.7	-0.0	0.7	0.5	0.9	0.9
Financial situation satisfaction	0.4	0.5	2.2	-0.1	-1.1	-1.5	-0.5	-0.8	-0.8	-1.2	0.2	-0.2	-0.3	-0.0	0.5	-0.3	-0.6	-0.8
Medication: Atorvastatin	0.4	0.5	2.5	-1.4	-0.7	0.0	-0.5	-0.4	-0.1	1.6	0.3	0.2	-0.5	0.4	-0.4	-1.2	0.1	-0.1
Illnesses of father: High blood pressure	0.4	0.5	1.8	-0.9	0.5	-1.0	-0.4	-0.1	-0.2	-0.7	-1.3	-0.6	-1.1	-0.0	0.7	0.8	-0.2	-0.2
Pain experienced in last month	0.4	0.6	1.5	-0.7	0.9	-0.7	-0.7	0.7	-0.7	0.8	-1.1	-1.0	-1.2	-0.1	0.3	-0.6	-0.5	-0.8
Pack years of smoking	0.4	0.5	2.4	0.3	-0.7	-0.3	-0.8	-1.0	-0.1	-1.6	-1.4	-0.2	-0.7	0.0	0.0	0.9	-0.3	-0.1
Bipolar Disorder or Schizophrenia	0.3	0.8	2.2	-1.0	-0.4	-1.5	-0.9	-1.3	-1.0	-1.0	-0.7	-0.8	-1.0	0.2	0.6	-0.1	-0.5	-1.0
Prostate Cancer	0.3	0.4	1.0	-0.9	1.0	-0.4	0.1	0.8	-0.4	-0.9	-0.3	0.7	-0.2	0.5	0.1	0.7	-0.5	-0.4
Smoking Status	0.3	0.7	4.8	0.4	-0.5	-0.3	-0.3	-0.5	-0.2	-0.0	0.6	0.4	-0.1	-1.6	-2.2	-0.9	-0.4	-0.2
Lung FVC	0.3	1.6	3.7	0.0	-0.5	-1.0	-1.2	-1.8	-1.7	-0.5	1.0	-1.4	-0.1	-1.5	-1.6	-1.0	-1.9	-1.6
Hearing difficulty/problems: Yes	0.3	0.4	1.4	-1.1	-0.4	-0.4	0.6	0.4	-0.5	-0.9	-0.0	-1.2	-0.7	-0.3	-0.4	-0.6	-0.8	-0.6
Pack years adult smoking proportion	0.3	0.4	1.3	0.2	-1.0	-0.2	-0.9	-1.0	0.1	-1.1	-1.1	-0.1	-0.6	0.0	-0.1	0.8	-0.2	0.1
Townsend deprivation index at recruitment	0.3	0.4	1.3	-0.6	-0.8	-0.2	-0.2	-0.3	0.2	0.4	-1.1	-0.7	-1.0	-0.9	-0.3	-1.1	0.1	0.0
Stomach or abdominal pain in last month	0.3	0.4	1.0	-0.4	-0.0	-0.7	-0.7	0.6	-0.7	-1.0	0.8	0.3	0.3	0.5	0.3	0.7	-1.0	-0.6
Alcohol usually taken with meals	0.3	0.5	1.7	-0.1	0.2	-0.9	0.4	-0.3	-0.7	-0.8	0.4	-1.3	-0.1	-0.8	-0.7	-1.2	-0.7	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.5	-0.1	0.1	-1.0	-0.2	0.3	-1.1	-0.6	0.3	-0.7	-0.4	-0.1	-0.2	0.5	-1.2	-1.1
Had other major operations	0.3	0.4	1.5	-1.2	0.3	-0.5	0.4	1.1	-0.2	0.1	-0.7	-0.8	-0.4	0.3	-0.1	0.5	-0.9	-0.2
Allergy	0.3	0.7	4.6	1.1	2.1	1.1	0.9	0.0	0.7	-0.3	-0.2	-0.2	0.6	-0.3	-0.5	-0.1	0.9	0.7
Falls in the last year	0.3	0.3	2.9	-0.2	-0.8	-0.2	0.1	0.5	-0.0	-1.7	0.0	0.1	0.8	0.4	0.4	0.6	-0.3	0.0
Pulse rate	0.3	0.6	1.5	-0.9	-1.0	-0.1	0.0	0.5	-0.9	-0.0	-0.4	-0.5	-0.7	-0.7	-0.8	-1.1	-1.2	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	2.0	-0.9	-0.2	-1.0	-0.7	-1.4	-0.1	-0.7	-0.2	-0.5	-0.4	-0.2	-0.1	-0.3	-0.0	-0.1
Medication: Cholesterol lowering	0.3	0.5	1.9	0.5	0.7	0.5	0.7	0.7	0.5	0.9	-0.0	0.8	0.5	1.4	0.5	0.8	0.7	0.4
Exposure to tobacco smoke at home	0.3	0.3	1.1	-0.4	-0.4	-0.5	-0.7	-0.3	-0.9	0.3	-0.6	-0.4	-1.0	-0.3	0.4	-0.1	-0.6	-0.8
Breastfed as a baby	0.3	0.4	2.3	-1.5	0.1	-0.2	-0.3	-0.3	-0.5	-1.4	0.2	0.2	-0.1	-0.3	0.4	-0.2	-0.7	-0.4
Medication: Amlodipine	0.3	0.4	1.8	0.5	-0.5	0.1	-0.3	-0.9	0.7	0.1	-0.9	-0.4	0.2	-0.6	-0.3	-1.3	0.5	0.5
Body fat percentage	0.3	1.3	6.4	-0.5	0.8	1.2	1.0	2.5	1.6	-0.1	-1.2	0.7	-0.4	0.5	0.3	0.6	1.7	1.5
Pulse wave peak to peak time	0.3	0.4	1.7	-1.0	1.3	0.3	0.3	0.0	0.3	0.3	-0.6	-0.5	-0.6	-0.8	-0.6	-0.3	-0.3	0.2
Neck or shoulder pain in last month	0.3	0.5	1.1	-1.0	-0.5	-0.9	-0.4	-1.0	-0.7	-0.4	1.1	-0.4	-0.4	-0.2	0.7	-0.7	-0.7	-0.6
Whole body fat mass	0.3	1.3	3.0	-1.6	-0.3	-0.8	-1.0	1.7	-0.7	-1.6	-1.6	-0.7	-1.7	-1.0	-1.1	-0.8	-0.5	-0.7
Leg fat mass (right)	0.3	1.1	5.8	-1.4	-0.0	-0.6	-0.6	2.4	-0.5	-1.5	-1.3	-0.4	-1.4	-0.8	-0.6	-0.7	-0.4	-0.6
Number of full sisters	0.3	0.4	1.6	-0.4	-0.7	-0.5	-0.9	0.7	-0.5	-0.5	0.3	0.3	-0.2	-1.3	-0.2	-0.9	-0.7	-0.5
Family relationship satisfaction	0.3	0.3	1.4	-0.1	0.6	-0.5	-0.2	1.2	-0.5	1.2	0.5	-0.2	-0.2	0.0	0.1	-0.7	-0.5	-0.6
Arm fat percentage (left)	0.3	1.1	4.2	-0.6	0.6	1.0	1.0	2.0	1.5	0.1	-1.5	0.3	-0.5	0.5	0.3	0.4	1.6	1.3
Average weekly red wine intake	0.3	0.5	2.1	-0.1	0.5	0.4	-0.2	0.0	-0.8	1.0	1.4	-0.3	-0.4	-0.3	-0.2	-1.5	-0.4	-0.7
Ever had bowel cancer screening	0.3	0.4	1.6	0.3	0.3	-0.7	-0.1	1.0	-0.6	-1.3	0.4	-0.7	0.2	-0.9	-0.3	-0.3	-0.5	-0.6
Smoking status: Current	0.3	0.5	2.3	0.4	-1.5	0.2	-0.6	-0.8	-0.3	0.8	0.3	0.3	-0.3	-0.6	-0.9	-0.9	-0.4	-0.3
Number of self-reported non-cancer illnesses	0.3	0.6	3.0	-1.0	1.2	-0.0	0.7	1.7	-0.1	-0.1	-1.0	-0.5	-0.8	0.5	0.5	0.0	-0.1	-0.1
Medication: Blood pressure	0.3	0.6	1.9	-1.3	0.2	-0.4	-1.1	-0.9	0.0	1.3	-1.4	-0.3	-1.0	0.3	-0.0	-1.0	0.0	-0.1
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.8	-1.3	0.5	-0.1	0.0	-0.3	0.7	-0.5	-0.4	0.7	-0.2	0.3	0.6	0.7	0.7	0.7
Average weekly beer plus cider intake	0.3	0.5	3.0	0.2	0.6	0.5	0.7	-0.2	0.5	0.3	-0.2	0.6	0.4	0.8	1.7	0.2	0.9	0.6
Age started oral contraceptive pill	0.3	0.4	1.0	0.3	0.9	0.5	0.9	1.0	0.7	-0.5	-0.7	0.4	0.3	0.1	0.9	0.3	0.6	0.7
Commuting to job workplace: Cycle	0.3	0.4	1.8	0.1	-0.4	0.3	0.3	1.2	-0.2	1.3	0.8	-0.1	-0.0	0.2	0.9	-0.4	-0.4	-0.2
Leg fat mass (left)	0.3	1.1	4.1	-1.5	-0.3	-0.6	-0.6	2.0	-0.3	-1.6	-1.5	-0.5	-1.5	-0.8	-0.7	-0.6	-0.2	-0.3
Fasting Glucose	0.2	0.2	0.8	-0.1	-0.4	0.1	0.1	0.3	0.7	-0.4	-0.2	0.0	0.4	0.4	0.6	0.9	0.6	0.6
Blood Eosinophil Count	0.2	1.3	6.2	-1.0	-0.5	0.2	-0.3	-1.2	1.1	-2.5	-1.1	0.6	-0.5	-0.6	2.0	1.2	0.8	1.1
Blood Platelet Count	0.2	2.4	7.0	2.3	-1.7	0.6	-1.3	-1.0	0.3	-2.5	0.6	0.4	0.2	1.9	2.6	2.3	0.9	0.7
BMI	0.2	1.0	4.8	-1.9	-0.9	-0.2	-0.2	1.2	0.5	-0.4	-2.2	-0.2	-1.4	-0.7	-0.5	-1.3	0.4	0.3
Hypothyroidism (self reported)	0.2	0.5	2.5	-0.7	-1.6	0.5	-0.2	-0.4	0.1	-0.9	0.4	-0.1	-0.4	-0.6	-1.5	0.3	-0.8	0.1
Hair Pigment	0.2	6.4	13.5	2.8	2.4	2.9	3.7	-0.1	3.5	2.8	1.4	2.4	2.6	1.1	0.4	1.3	3.5	3.3
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.5	0.2	-0.3	0.1	0.6	0.2	0.4	-0.7	-0.6	0.5	0.5	0.4	0.2	0.5	0.5	0.4
Trunk fat percentage	0.2	0.7	3.8	-0.9	0.5	0.5	0.4	1.9	0.9	-0.7	-1.3	0.0	-0.9	-0.2	-0.3	0.1	1.0	0.7
Body mass index (BMI)	0.2	0.7	3.4	-1.5	-0.1	-0.1	-0.1	1.5	0.6	-0.3	-1.9	-0.1	-1.1	-0.1	-0.2	-0.4	0.6	0.5
Waist circumference	0.2	0.7	4.8	-1.0	0.8	-0.0	0.5	2.2	0.2	-1.0	-1.2	-0.0	-1.0	0.2	0.4	0.0	0.1	0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.3	-0.0	0.0	-0.9	-0.3	0.5	-0.3	0.7	1.1	0.1	0.2	-0.4	-0.5	-0.7	-0.6	-0.3
Medication: Simvastatin	0.2	0.3	1.4	0.5	1.2	-0.1	0.2	0.5	0.2	0.4	-0.8	-0.3	0.0	1.1	0.7	0.7	-0.0	0.1
Arm fat percentage (right)	0.2	1.0	3.7	-0.9	0.5	0.6	0.8	1.9	1.2	-0.1	-1.9	-0.1	-0.8	0.1	0.1	-0.1	1.3	1.0
Alcohol intake versus 10 years previously	0.2	0.3	1.5	0.6	0.3	0.0	0.9	1.2	0.3	0.2	-0.2	0.6	0.1	0.5	0.3	1.0	0.2	0.3
Number of live births	0.2	0.3	0.9	-0.8	-0.2	-0.1	-0.1	0.4	-0.1	-0.6	-0.6	-0.4	-0.7	-0.8	-0.9	0.1	-0.6	-0.1
Lung cancer (father)	0.2	0.2	0.8	0.5	0.4	-0.4	-0.4	0.7	0.0	-0.2	-0.8	-0.2	-0.3	-0.9	0.1	-0.4	0.3	0.0
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.4	-0.4	-1.2	1.1	0.8	0.2	0.4	-0.1	0.7	0.4	0.2	0.3	-1.2	0.4	-0.2	0.4
Medication: Aspirin	0.2	0.3	1.6	-1.3	-0.6	0.3	-0.3	0.5	-0.3	0.1	-0.4	0.6	0.3	0.6	-0.2	-0.5	-0.2	-0.3
Supplements: Vitamin C	0.2	0.2	0.9	-0.4	0.1	-0.5	-0.2	0.9	-0.2	-0.9	-0.2	-0.2	-0.0	-0.5	0.3	0.4	-0.3	-0.2
Commuting to job workplace: Walk	0.2	0.3	1.6	-0.7	0.2	0.4	0.3	0.7	0.3	0.5	-1.3	-0.1	-0.5	-0.1	0.6	0.1	-0.0	0.3
Breast cancer (self-reported)	0.2	0.2	1.8	1.4	0.3	0.3	0.3	0.0	0.3	-0.3	-0.5	0.2	0.7	-0.0	0.3	0.5	-0.3	0.2
Medication: Aspirin	0.2	0.3	0.9	-0.8	-0.9	0.7	-0.2	0.2	0.2	0.5	-0.9	0.6	0.4	0.7	-0.2	-0.5	0.2	0.2
Ever taken oral contraceptive pill	0.2	0.2	1.2	0.2	-0.6	0.0	0.5	-0.4	0.3	-0.1	-0.1	0.2	-0.2	-1.1	-0.9	-0.6	0.2	0.2
Cholesterol lowering medication	0.2	0.3	1.7	-0.3	0.3	0.3	-0.2	-0.5	0.6	1.3	0.1	0.5	0.5	0.8	0.8	-0.2	0.4	0.6
Heart disease (siblings)	0.2	0.3	1.1	-0.2	0.3	-0.4	0.7	-0.9	0.5	-1.0	-0.0	-0.3	-0.1	-0.4	0.1	-0.9	0.7	0.3
Blood Red Count	0.1	0.6	2.3	-1.0	0.8	0.1	-0.1	0.9	0.8	-0.6	0.1	1.1	-0.2	0.2	0.6	1.5	0.9	0.8
Blood White Count	0.1	1.0	3.1	0.2	0.8	0.2	-0.2	-1.1	1.0	-1.6	-1.3	-0.7	-1.8	0.2	1.0	0.8	1.2	1.0
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.7	-0.0	0.5	-0.4	-0.6	-0.8	-0.5	0.4	0.7	0.0	0.3	0.2	0.5	0.2	-0.4	-0.4
Tense / ‘highly strung’	0.1	0.2	1.0	-0.2	1.0	-0.2	-0.4	0.5	-0.5	-0.2	0.1	-0.3	-0.3	0.4	-0.3	-0.4	-0.5	-0.5
Medication: Ibuprofen	0.1	0.1	0.5	-0.4	-0.4	-0.3	-0.1	-0.7	0.4	-0.4	0.2	-0.0	-0.1	-0.1	-0.4	-0.2	0.5	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.5	0.0	-0.4	0.1	-0.4	0.7	0.1	-0.4	-0.1	0.5	0.7	-0.3	-0.2	0.1	0.0	0.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.7	-0.1	-0.6	-0.2	0.1	-0.6	-0.4	-0.4	0.8	-0.7	0.8	0.1	-0.1	0.5	-0.4	-0.4
Tanning	0.0	0.4	1.1	-0.6	-0.3	0.0	-0.4	0.3	-0.4	1.0	-0.1	-0.5	-0.5	-1.0	-0.7	-0.9	-0.5	-0.5

Hub : Genes

PSMB3

Models

Trait associations