Best TWAS P=6.9e-08 · Best GWAS P=1.89e-09 conditioned to 0.000129
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | METTL21A | 0.10 | 0.02 | lasso | 4 | 0.02 | 0.016 | -4.3 | 5.2 | 2.2e-07 | 0.32 | 0.23 | 0.06 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | CREB1 | 0.15 | 0.00 | enet | 7 | 0.00 | 0.277 | -4.3 | -5.4 | 6.9e-08 | -0.50 | 0.13 | 0.44 | TRUE |