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Leg predicted mass (left)
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chr2:217,456,567-219,320,207
Best TWAS P=9.98e-16 · Best GWAS P=1.66e-28 conditioned to 3.4e-10
217.5M
218M
218.5M
219M
0
5
10
15
20
25
30
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
DIRC3
0.08
0.06
lasso
5
0.07
2.7e-07
-8.7
8.0
1.0e-15
-0.56
0.98
0.01
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
DIRC3
0.12
0.07
bslmm
697
0.08
2.7e-10
-5.9
6.5
7.5e-11
0.00
1.00
0.00
TRUE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
DIRC3
0.12
0.01
blup
275
0.02
3.3e-03
-1.1
6.3
2.5e-10
-0.51
0.05
0.52
TRUE