Best TWAS P=9.98e-16 · Best GWAS P=1.66e-28 conditioned to 3.4e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | DIRC3 | 0.12 | 0.07 | bslmm | 697 | 0.08 | 2.7e-10 | -5.9 | 6.5 | 7.5e-11 | 0.00 | 1.00 | 0.00 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | DIRC3 | 0.12 | 0.01 | blup | 275 | 0.02 | 3.3e-03 | -1.1 | 6.3 | 2.5e-10 | -0.51 | 0.05 | 0.52 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | DIRC3 | 0.08 | 0.06 | lasso | 5 | 0.07 | 2.7e-07 | -8.7 | 8.0 | 1.0e-15 | -0.56 | 0.98 | 0.01 | TRUE |