[Hub]/) : Traits : Arm fat percentage (right) :

chr17:1,151,592-2,923,933

Best TWAS P=5.63e-13 · Best GWAS P=2.54e-20 conditioned to 6.3e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SRR 0.16 0.16 lasso 9 0.18 1.9e-14 -5.6 6.4 1.8e-10 -0.07 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum SRR 0.29 0.26 lasso 5 0.25 1.8e-13 -5.1 5.4 5.5e-08 -0.05 1.00 0.00 FALSE
3 GTEx Adrenal Gland SRR 0.38 0.37 lasso 6 0.38 8.1e-15 -5.1 5.7 1.2e-08 -0.06 1.00 0.00 FALSE
4 GTEx Artery Aorta SRR 0.33 0.33 lasso 2 0.32 6.1e-18 -5.1 5.1 2.8e-07 -0.03 1.00 0.00 FALSE
5 GTEx Artery Coronary SRR 0.44 0.28 lasso 8 0.26 2.5e-09 -5.6 5.7 8.9e-09 -0.06 0.99 0.00 FALSE
6 GTEx Artery Tibial SRR 0.22 0.23 lasso 4 0.24 3.9e-19 -5.6 5.5 3.3e-08 -0.06 1.00 0.00 FALSE
7 GTEx Brain Caudate basal ganglia SRR 0.26 0.03 lasso 3 0.02 8.6e-02 -4.4 5.5 3.7e-08 -0.03 0.13 0.06 FALSE
8 GTEx Brain Cerebellar Hemisphere SRR 0.37 0.24 lasso 7 0.22 2.1e-06 -5.1 5.2 1.8e-07 -0.02 0.62 0.02 FALSE
9 GTEx Brain Cerebellum SRR 0.26 0.20 lasso 3 0.21 8.7e-07 -5.1 5.8 7.6e-09 -0.03 0.39 0.04 FALSE
10 GTEx Brain Frontal Cortex BA9 SRR 0.25 0.24 lasso 3 0.21 3.5e-06 -5.1 5.2 2.1e-07 -0.03 0.27 0.07 FALSE
11 GTEx Breast Mammary Tissue SRR 0.20 0.21 lasso 3 0.20 8.2e-11 -5.6 5.7 1.1e-08 -0.07 1.00 0.00 FALSE
12 GTEx Breast Mammary Tissue (Female) SRR 0.24 0.25 lasso 3 0.21 6.3e-07 -5.6 5.7 1.1e-08 -0.07 0.78 0.02 FALSE
13 GTEx Cells EBV-transformed lymphocytes SRR 0.39 0.34 lasso 5 0.35 3.1e-12 -5.1 5.6 2.2e-08 -0.04 1.00 0.00 FALSE
14 GTEx Cells Transformed fibroblasts SRR 0.36 0.38 lasso 4 0.38 8.2e-30 -5.1 5.3 1.3e-07 -0.03 1.00 0.00 FALSE
15 GTEx Colon Sigmoid SRR 0.32 0.35 enet 8 0.32 9.2e-12 -5.1 5.4 5.6e-08 -0.05 1.00 0.00 FALSE
16 GTEx Esophagus Mucosa SRR 0.23 0.24 lasso 5 0.24 2.0e-16 -5.6 5.8 6.0e-09 -0.06 1.00 0.00 FALSE
17 GTEx Esophagus Muscularis SRR 0.30 0.39 lasso 3 0.38 3.4e-24 -5.1 5.1 2.6e-07 -0.03 1.00 0.00 FALSE
18 GTEx Heart Atrial Appendage SRR 0.35 0.30 lasso 7 0.29 1.4e-13 -5.6 5.5 2.9e-08 -0.05 1.00 0.00 FALSE
19 GTEx Liver SRR 0.31 0.00 lasso 7 0.00 3.0e-01 -6.6 7.2 5.6e-13 -0.40 0.06 0.14 TRUE
20 GTEx Lung SRR 0.24 0.28 lasso 2 0.26 3.4e-20 -5.1 5.1 2.9e-07 -0.04 1.00 0.00 FALSE
21 GTEx Muscle Skeletal SRR 0.27 0.27 lasso 6 0.27 7.1e-27 -5.1 5.3 9.9e-08 -0.04 1.00 0.00 FALSE
22 GTEx Nerve Tibial SRR 0.15 0.13 lasso 3 0.13 2.9e-09 -5.6 5.5 3.1e-08 -0.06 1.00 0.00 FALSE
23 GTEx Pancreas SRR 0.13 0.17 lasso 3 0.15 5.2e-07 -5.6 5.5 3.7e-08 -0.06 0.96 0.00 FALSE
24 GTEx Skin Not Sun Exposed Suprapubic SRR 0.18 0.16 enet 18 0.19 7.9e-11 -5.1 5.2 1.5e-07 -0.04 0.98 0.00 FALSE
25 GTEx Skin Sun Exposed Lower leg SRR 0.13 0.15 lasso 4 0.14 2.0e-11 -5.1 5.3 1.2e-07 -0.04 1.00 0.00 FALSE
26 GTEx Skin Sun Exposed Lower leg RTN4RL1 0.19 0.11 lasso 6 0.11 2.0e-09 -4.2 5.1 2.6e-07 -0.28 1.00 0.00 TRUE
27 GTEx Spleen SRR 0.21 0.10 lasso 4 0.04 3.1e-02 -5.1 5.6 1.8e-08 -0.04 0.14 0.06 FALSE
28 GTEx Stomach SRR 0.27 0.30 lasso 7 0.28 7.1e-14 -5.6 5.5 3.2e-08 -0.07 1.00 0.00 FALSE
29 GTEx Testis SRR 0.13 0.12 lasso 2 0.09 6.6e-05 -5.7 5.6 2.0e-08 -0.07 0.57 0.02 FALSE
30 GTEx Thyroid SRR 0.26 0.27 lasso 4 0.25 2.0e-19 -5.1 5.1 2.7e-07 -0.03 1.00 0.00 FALSE
31 GTEx Whole Blood SRR 0.09 0.03 enet 8 0.02 4.5e-03 -5.1 5.4 5.9e-08 -0.04 0.75 0.01 FALSE
32 METSIM Adipose SRR 0.07 0.07 enet 21 0.06 4.4e-09 -5.1 5.4 6.1e-08 -0.01 1.00 0.00 FALSE
33 ROSMAP Brain Pre-frontal Cortex SRR 0.25 0.39 lasso 3 0.39 5.6e-53 -5.1 5.3 1.4e-07 -0.03 1.00 0.00 FALSE
34 YFS Blood SRR 0.17 0.22 lasso 7 0.23 2.5e-72 -5.1 5.4 5.8e-08 -0.04 1.00 0.00 FALSE
35 The Cancer Genome Atlas Bladder Urothelial Carcinoma SRR 0.11 0.09 lasso 4 0.10 6.8e-09 -5.1 5.5 3.7e-08 -0.04 0.01 0.99 FALSE
36 The Cancer Genome Atlas Breast Invasive Carcinoma SRR 0.16 0.16 lasso 5 0.16 2.3e-32 -5.6 5.7 1.3e-08 -0.07 0.00 1.00 FALSE
37 The Cancer Genome Atlas Esophageal Carcinoma SRR 0.32 0.13 lasso 2 0.16 9.2e-06 -5.7 5.6 1.7e-08 -0.07 0.00 0.99 FALSE
38 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SRR 0.10 0.10 lasso 2 0.09 1.0e-10 -5.1 5.3 1.2e-07 -0.04 0.01 0.99 FALSE
39 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SRR 0.30 0.40 lasso 7 0.39 8.5e-47 -5.6 5.8 6.5e-09 -0.07 0.00 1.00 FALSE
40 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SRR 0.22 0.23 lasso 2 0.21 2.3e-12 -5.1 5.2 2.5e-07 -0.03 0.02 0.98 FALSE
41 The Cancer Genome Atlas Brain Lower Grade Glioma SRR 0.29 0.26 lasso 2 0.27 1.9e-30 -5.6 5.7 1.2e-08 -0.07 0.00 1.00 FALSE
42 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SRR 0.08 0.09 enet 3 0.08 1.7e-04 -5.1 5.3 1.1e-07 -0.04 0.01 0.96 FALSE
43 The Cancer Genome Atlas Lung Adenocarcinoma SRR 0.14 0.18 lasso 2 0.18 4.3e-21 -5.1 5.3 1.1e-07 -0.04 0.02 0.98 FALSE
44 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SRR 0.16 0.20 lasso 3 0.20 2.8e-13 -5.6 5.7 1.3e-08 -0.07 0.01 0.99 FALSE
45 The Cancer Genome Atlas Pancreatic Adenocarcinoma SRR 0.34 0.30 lasso 4 0.30 2.9e-13 -5.1 5.4 5.3e-08 -0.04 0.01 0.99 FALSE
46 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma SRR 0.27 0.19 enet 5 0.21 8.9e-09 -5.6 5.7 1.2e-08 -0.07 0.00 1.00 FALSE
47 The Cancer Genome Atlas Prostate Adenocarcinoma SRR 0.30 0.35 lasso 3 0.36 7.5e-39 -5.1 5.4 6.0e-08 -0.04 0.02 0.98 FALSE
48 The Cancer Genome Atlas Soft Tissue Sarcoma SRR 0.20 0.18 lasso 2 0.20 8.8e-12 -5.1 5.4 6.5e-08 -0.05 0.01 0.99 FALSE
49 The Cancer Genome Atlas Skin Cutaneous Melanoma SRR 0.16 0.03 blup 61 0.02 8.7e-02 -5.7 5.6 2.8e-08 -0.07 0.01 0.71 FALSE
50 The Cancer Genome Atlas Testicular Germ Cell Tumors SGSM2 0.13 0.01 blup 81 0.01 1.1e-01 4.4 -6.2 6.9e-10 0.08 0.02 0.40 TRUE
51 The Cancer Genome Atlas Thyroid Carcinoma SRR 0.56 0.50 lasso 4 0.50 5.2e-55 -5.1 5.3 1.4e-07 -0.03 0.07 0.92 FALSE