Hub : Genes

SGSM2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1310	0.0410	1.6e-03	0.077	0.011	0.040	0.058	0.067	1.2e-09	1.3e-02	1.1e-05	1.2e-07	1.3e-08
2	GTEx	Artery Aorta	0.1390	0.0520	3.3e-03	-0.004	NA	0.001	NA	-0.004	6.8e-01	NA	2.9e-01	NA	6.4e-01
3	GTEx	Artery Tibial	0.1219	0.0475	4.8e-04	0.017	NA	0.046	NA	0.037	1.5e-02	NA	1.6e-04	NA	6.5e-04
4	GTEx	Esophagus Mucosa	0.2770	0.0610	3.1e-11	0.317	NA	0.315	NA	0.320	1.1e-21	NA	1.5e-21	NA	6.8e-22
5	GTEx	Nerve Tibial	0.2418	0.0734	2.2e-03	0.085	NA	0.030	NA	0.079	1.2e-06	NA	3.2e-03	NA	3.3e-06
6	GTEx	Skin Not Sun Exposed Suprapubic	0.3730	0.0760	2.9e-07	0.353	NA	0.407	NA	0.398	3.4e-20	NA	6.6e-24	NA	3.0e-23
7	GTEx	Skin Sun Exposed Lower leg	0.4990	0.0630	5.6e-17	0.469	NA	0.508	NA	0.505	3.5e-43	NA	3.3e-48	NA	7.7e-48
8	YFS	Blood	0.0535	0.0144	1.4e-07	0.026	0.022	0.033	0.030	0.033	3.7e-09	7.6e-08	5.6e-11	3.6e-10	3.9e-11
9	TCGA	Testicular Germ Cell Tumors	0.1260	0.0590	8.8e-03	0.008	0.013	-0.008	NA	0.008	1.6e-01	1.1e-01	8.4e-01	NA	1.6e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.5	0.8	2.9	-1.7	1.3	-0.1	0.6	-1.0	0.3	0.4	0.2	1.0
Bipolar Disorder or Schizophrenia	1.7	4.1	12.3	-1.7	0.6	-1.6	2.5	-1.6	2.0	2.3	-1.0	3.5
Depressed Affect (Nagel 2018)	0.5	1.1	4.1	-0.5	-1.3	-0.5	-0.2	-0.3	-1.1	-1.2	1.0	-2.0
Depression (Nagel 2018)	0.8	1.3	5.9	-0.2	-0.6	-0.3	-0.8	0.1	-0.9	-1.3	1.4	-2.4
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.7	0.2	0.6	0.9	0.3	0.4	1.1	0.9	1.2	1.3
Neuroticism (Nagel 2018)	1.0	2.3	8.6	-0.8	-2.6	-0.6	0.4	-0.5	-1.3	-1.1	0.9	-2.9
Schizophrenia (2018)	2.5	5.3	13.8	-0.8	-0.2	-2.5	2.7	-1.2	2.4	2.6	-2.4	3.7
Schizophrenia vs Biploar Disorder	1.1	1.4	3.2	0.6	-1.8	-1.7	1.2	-0.2	0.3	0.4	-1.8	1.1
Worry (Nagel 2018)	1.2	2.5	8.3	-0.6	-2.4	0.5	-0.3	0.1	-2.1	-1.6	1.0	-2.9
Alzheimer’s Disease (in mother)	0.3	0.3	1.7	0.0	1.3	0.3	0.2	0.3	0.7	0.3	0.3	-0.4
Alzheimer’s Disease (in father)	0.6	0.7	4.8	0.3	2.2	0.5	-0.1	-0.0	-0.2	0.3	-0.3	-0.8
Alzheimer’s Disease (including proxy)	0.5	0.7	5.1	0.3	2.3	0.7	-0.4	0.3	-0.2	-0.2	-0.2	-0.5
Crohns Disease (2017)	0.8	1.7	5.4	0.2	0.5	-0.5	1.8	0.3	2.3	1.9	1.0	1.3
Irritable Bowel Disease (IBD)	1.7	4.1	11.7	-1.6	0.9	0.1	2.4	-1.1	3.4	3.0	1.7	1.7
Ulcerative Colitis (UC)	1.8	3.3	8.2	-1.8	1.2	0.7	1.8	-1.2	2.9	2.6	1.6	1.5
Major Depression (MDD)	0.2	0.2	0.7	0.0	0.1	0.5	-0.4	0.9	0.0	-0.2	0.2	0.7
Reaction Time	0.4	0.8	1.7	-0.9	1.3	0.7	-1.3	-0.8	-0.9	-1.1	0.6	0.1
Verbal and Numeric Reasoning (VNR)	0.2	0.4	2.3	-0.6	0.5	0.7	-0.1	0.1	-0.3	-0.2	1.5	-0.6
Breast Cancer	0.9	2.1	9.9	1.3	-3.1	-0.5	0.2	1.0	-0.1	-0.1	-0.2	2.4
Ovarian Cancer	0.6	0.8	3.0	-1.7	-0.8	0.1	-0.7	-1.6	-0.3	-0.6	0.4	0.6
Prostate Cancer	0.2	0.2	0.6	0.4	0.8	0.3	-0.6	0.4	-0.7	-0.2	-0.7	-0.2
Age at First Birth	0.5	0.8	2.8	1.3	0.4	0.8	-0.1	1.7	-0.1	0.1	0.2	1.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	1.5	2.1	7.8	-1.5	-0.7	1.1	-1.3	-1.0	-0.9	-1.3	1.4	-2.8
Coronary Artery Disease (CAD)	2.3	2.7	10.0	-0.5	0.3	2.6	-1.0	-0.5	-0.8	-0.8	2.1	-3.2
Crohns Disease (2012)	0.7	1.1	3.5	0.4	-0.7	0.0	1.7	0.2	1.7	1.9	0.1	0.7
Mean Putamen Volume	0.7	0.7	2.4	-1.4	0.8	-0.6	0.7	-1.6	0.6	0.6	0.5	-0.1
Fasting Glucose	0.2	0.3	1.0	-0.3	-0.4	-1.0	0.1	-0.4	-0.5	-0.4	-0.1	0.7
HbA1C	0.3	0.3	1.9	0.7	1.4	0.1	-0.0	0.3	0.5	0.1	-0.2	0.3
HDL Cholesterol	1.7	2.9	5.2	0.6	-2.0	-2.3	2.3	0.4	1.8	1.8	-1.7	1.5
LDL Cholesterol	2.4	3.8	11.4	-0.9	-1.9	-3.1	1.9	-1.3	1.3	1.3	-3.4	0.4
Lupus	0.2	0.4	1.1	-0.4	-1.0	-1.0	0.0	-0.5	0.5	-0.1	-0.2	0.7
Neuroticism (2016)	1.6	2.3	8.4	-1.1	-2.9	-2.0	1.4	-0.8	0.5	0.3	-1.3	-1.7
Primary Biliary Cirrhosis	0.6	0.9	2.1	-1.4	-0.9	0.7	0.6	-0.6	0.7	0.5	1.4	1.0
Rheumatoid Arthritis	0.7	1.0	4.4	-0.5	-1.5	0.3	-0.3	-0.6	-0.5	-0.5	0.9	-2.1
Schizophrenia (2014)	2.6	5.7	15.1	-0.7	-0.8	-2.7	2.9	-1.0	2.2	2.4	-2.7	3.9
Triglycerides	0.1	0.2	0.8	0.2	-0.2	-0.1	0.5	0.3	0.2	0.4	-0.9	-0.3
Type 2 Diabetes (T2D) (2012)	1.1	1.2	4.3	0.7	1.3	1.8	-0.9	0.7	-0.4	-0.4	2.1	0.2
Ulcerative Colitis	3.1	4.5	9.8	-2.5	0.4	1.1	2.3	-1.8	3.1	3.1	1.5	1.6
Blood Eosinophil Count	0.6	5.0	15.8	1.5	2.6	4.0	-1.9	1.3	-0.9	-1.0	3.5	0.3
Blood Platelet Count	3.3	38.1	84.8	0.8	-1.4	-8.0	9.2	-1.3	4.9	6.4	-8.3	7.4
Blood Red Count	0.3	3.1	10.3	0.3	-0.7	2.4	-3.2	0.3	-2.0	-2.3	0.4	-1.3
Blood White Count	2.1	15.5	34.8	-0.9	0.5	-4.1	5.2	-2.2	4.5	4.8	-3.3	5.9
Heel T-Score	3.8	30.1	84.1	-0.0	-0.1	5.8	-7.2	1.4	-4.4	-5.3	7.2	-9.2
BMI	1.6	9.2	50.7	-0.5	0.5	0.8	-3.1	-0.7	-2.8	-3.6	0.7	-7.1
Height	0.2	3.1	7.6	1.0	-2.5	1.9	-0.6	1.7	0.6	-0.1	2.8	2.4
Waist Hip Ratio (WHR)	1.6	7.4	15.4	0.5	0.5	3.0	-3.9	0.9	-3.1	-3.8	2.3	-3.4
Systolic Blood Pressure	1.8	8.9	16.6	4.1	-3.9	0.4	-1.2	3.2	-3.1	-2.7	-2.2	-3.8
Smoking Status	2.2	5.3	13.1	0.8	1.6	-2.1	2.0	0.4	3.6	3.0	-1.3	3.4
Allergy or Eczema	3.4	8.9	34.7	-1.9	1.6	-0.9	3.0	-1.7	3.7	3.5	0.3	5.9
Cardiovascular Disease	0.5	1.8	9.4	1.4	-1.3	0.3	-0.3	1.4	-0.8	-0.8	0.1	-3.1
Hypothyroidism (self reported)	0.3	0.6	1.8	-1.3	0.1	-1.3	0.1	-1.0	0.6	0.3	-0.4	-0.5
Respiratory disease	0.6	1.4	3.8	0.6	0.5	1.3	-1.9	0.5	-1.0	-1.3	0.8	-1.7
Type 2 Diabetes (T2D) (2018)	0.2	0.5	3.1	0.1	1.8	0.4	-0.1	0.0	0.8	0.3	0.3	-0.3
Lung FEV1/FVC ratio	2.3	11.5	25.2	-1.4	0.4	-3.7	4.5	-2.2	3.8	4.0	-2.7	5.0
Lung FVC	0.8	4.0	11.0	1.8	-0.6	0.9	-2.2	1.1	-2.8	-2.6	0.2	-3.3
Neuroticism	1.3	3.0	9.9	-2.0	-3.1	-1.8	0.9	-1.8	-0.3	-0.3	-0.3	-2.4
Chronotype (morning person)	0.2	0.5	1.5	1.2	-1.1	-0.6	0.1	0.9	0.4	0.4	-0.5	-0.2
Hair Pigment	0.1	2.3	6.0	0.5	1.8	2.4	-2.1	0.1	-1.0	-1.1	1.6	-1.3
Tanning	0.1	1.3	3.3	1.6	-1.1	0.4	-0.6	1.7	-1.8	-0.9	0.2	-0.5
Hand grip strength (left)	1.4	3.8	6.6	2.6	0.2	2.5	-1.7	2.4	-1.6	-1.5	2.3	-1.5
Number of treatments/medications taken	0.3	0.6	2.7	0.6	-0.3	-0.3	-0.2	0.7	-0.4	-0.7	-0.9	-1.6
Average weekly spirits intake	0.7	0.9	2.4	1.2	1.6	0.5	-0.0	1.5	0.6	0.2	0.8	-0.6
Sensitivity / hurt feelings	0.9	1.5	4.2	-1.0	-2.0	-2.1	1.2	-1.4	0.6	0.3	-0.6	-0.5
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.3	0.4	0.2	-0.3	-0.8	0.9	-1.2	-1.5	1.3	-1.8
Hearing difficulty/problems: Yes	0.9	1.3	3.9	0.6	-2.0	-1.0	1.9	0.7	1.3	0.9	0.3	-0.2
Relative age of first facial hair	1.9	4.0	7.7	-0.2	-2.5	-2.4	1.8	-1.3	1.9	1.8	-2.8	2.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.7	0.3	0.5	-0.3	0.1	0.1	0.1	0.2	-0.8	-0.2
Ever used hormone-replacement therapy (HRT)	2.3	2.9	8.2	1.1	-2.9	-1.6	1.5	0.1	1.9	1.8	-2.4	0.0
Ever had hysterectomy (womb removed)	0.7	0.8	5.7	-0.7	-2.4	-0.1	0.4	-0.6	0.2	0.1	-0.3	-0.6
Systolic blood pressure, automated reading	2.5	7.3	25.4	2.7	-3.3	0.7	-1.5	2.0	-2.8	-2.5	-1.2	-5.0
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	3.2	0.8	1.8	0.2	-0.1	0.4	0.6	0.2	0.6	0.5
Angina	1.7	2.2	3.6	1.5	-0.6	1.5	-1.7	1.5	-1.9	-1.8	0.0	-1.5
Medication for hormone replacement therapy	2.3	2.6	6.6	2.5	-2.6	-1.2	-0.3	1.6	-1.0	-1.0	-2.0	-0.7
Vitamin and mineral supplements	1.1	1.5	8.5	-0.9	-1.2	-0.0	-0.6	-1.2	-0.3	-0.6	0.5	-2.9
Supplements: Zinc	0.6	0.7	4.8	-0.5	-0.1	0.3	0.2	-0.2	0.3	0.5	0.8	2.2
Medication: Co-codamol	2.8	3.3	8.1	-0.4	1.7	-2.8	2.0	-0.8	2.4	1.9	-1.8	1.1
Medication: Metformin	1.1	1.6	8.4	1.5	2.9	-0.3	0.3	1.3	0.6	0.4	-0.7	0.8
Diabetes (father)	1.9	2.3	5.3	-0.7	-1.2	-1.5	1.4	-1.1	1.4	1.5	-2.3	1.9
Diabetes (mother)	0.2	0.3	1.0	-0.9	0.3	0.0	-0.3	-1.0	-0.6	-0.3	-0.2	-0.5
Severe depression (siblings)	1.7	1.9	6.4	-2.5	-0.4	-1.2	0.5	-2.5	0.6	0.3	-1.4	0.7
Pack years adult smoking proportion	2.0	3.1	9.6	0.4	-1.6	-3.1	1.8	-0.2	0.9	1.4	-3.0	0.3
Impedance of leg (right)	5.5	26.5	54.3	1.8	-4.9	-5.4	6.6	0.9	5.0	5.7	-5.0	7.4
Leg fat-free mass (left)	1.8	9.6	23.3	-0.0	2.0	3.0	-4.1	0.6	-3.0	-3.8	3.1	-4.8
Trunk fat percentage	1.4	5.6	19.5	0.6	-2.9	-2.6	-0.5	-0.3	-1.3	-1.8	-3.1	-4.4
Hand grip strength (right)	0.5	1.3	1.9	1.3	-1.4	1.1	-1.2	0.8	-1.3	-1.3	0.8	-0.9
Townsend deprivation index at recruitment	2.7	3.8	10.0	-0.1	0.7	-1.5	2.6	-0.1	3.2	3.1	-1.0	2.0
Current tobacco smoking	3.8	6.2	11.2	0.5	0.7	-3.1	3.0	-0.0	3.3	3.2	-2.1	3.3
Average weekly fortified wine intake	2.5	2.9	10.9	-1.3	3.3	-0.1	1.2	-1.3	2.2	2.0	0.5	1.1
Maternal smoking around birth	1.5	2.2	6.7	0.2	1.4	-2.6	0.6	-0.4	1.5	1.3	-2.2	1.5
Fed-up feelings	0.1	0.3	1.3	-0.5	0.4	-0.5	0.4	-0.0	0.1	-0.1	1.1	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	3.6	0.1	-0.1	-0.6	0.2	0.2	0.3	-0.0	0.4	-1.9
Relative age voice broke	1.2	1.8	5.0	-0.3	-0.7	-1.8	1.0	0.0	1.4	1.3	-1.6	2.2
Taking other prescription medications	0.4	0.7	3.5	0.1	-0.5	-0.8	0.3	0.1	0.2	-0.2	-1.3	-1.9
Age when periods started (menarche)	1.7	4.2	13.7	-0.6	0.1	-1.9	2.2	-1.1	1.9	2.1	-2.4	3.7
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.0	0.4	-1.0	0.4	-0.5	0.8	-0.1	-0.4	0.7	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	1.7	3.9	15.6	-0.5	-0.3	1.9	-2.1	-0.2	-1.2	-1.4	2.9	-3.9
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.6	0.7	0.9	0.1	-0.4	0.1	0.5	0.2	0.2	1.3
Qualifications: CSEs or equivalent	1.9	2.5	4.8	0.7	0.1	-2.0	2.1	0.4	1.9	1.9	-2.2	1.1
Serious illness, injury or assault to yourself	0.4	0.5	2.0	0.1	-0.8	-0.3	0.1	0.6	0.4	0.1	-1.1	-1.4
High blood pressure	1.7	4.9	25.8	0.4	-0.6	0.9	-1.7	0.9	-2.5	-2.4	0.8	-5.1
Hayfever, allergic rhinitis or eczema	2.7	5.9	24.4	-1.3	1.8	0.5	2.1	-0.8	2.9	2.7	1.7	4.9
Multivitamins +/- minerals	0.8	1.0	2.9	0.9	1.6	0.9	-0.5	1.2	-0.3	-0.1	0.6	1.7
Stomach or abdominal pain in last month	0.6	0.7	2.3	-1.5	0.2	0.8	-0.2	-1.2	0.1	-0.1	1.4	-0.2
Supplements: Glucosamine	3.8	4.9	9.5	0.7	1.6	2.4	-3.1	1.3	-2.7	-2.8	2.4	-1.8
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	2.5	0.8	-0.6	-0.6	1.6	0.3	1.1	1.5	-0.6	-0.7
Medication: Atenolol	1.3	1.6	5.5	-0.7	-0.7	0.3	-1.4	-0.5	-1.4	-1.7	0.9	-2.3
Medication: Levothyroxine sodium	0.4	0.6	1.4	-0.3	0.1	-0.2	0.9	0.3	1.2	1.2	0.8	-1.1
Sitting height	0.2	1.5	3.8	1.6	-0.8	0.5	-0.5	2.0	-1.7	-1.5	0.2	-0.9
Chronic bronchitis/emphysema (father)	0.3	0.4	0.8	0.1	0.9	-0.9	0.6	0.1	0.5	0.5	-0.6	-0.6
High blood pressure (mother)	0.7	1.0	3.8	2.0	0.8	-0.5	-0.4	1.6	-0.2	-0.3	-1.0	-0.2
Body mass index (BMI)	1.4	5.9	35.5	0.2	-0.4	-0.1	-2.4	-0.1	-2.0	-2.8	-0.3	-6.0
Impedance of leg (left)	6.1	29.8	57.0	1.4	-5.0	-6.0	7.0	0.4	5.3	6.1	-5.6	7.5
Leg predicted mass (left)	1.8	9.6	23.7	-0.1	1.9	3.0	-4.1	0.6	-3.0	-3.8	3.1	-4.9
Trunk fat mass	1.1	4.6	21.5	0.6	-2.0	-1.5	-1.4	0.1	-1.6	-2.4	-1.7	-4.6
Waist circumference	1.4	5.0	25.3	0.0	-0.3	0.4	-2.5	0.1	-2.0	-3.0	0.4	-5.0
Number of incorrect matches in round	1.0	1.7	3.4	1.2	0.3	-0.7	1.8	0.9	1.5	1.7	-0.8	1.7
Past tobacco smoking	1.1	2.0	6.9	-1.2	-1.4	-0.0	-0.4	-1.2	-1.9	-1.3	-0.7	-2.6
Alcohol usually taken with meals	3.3	5.4	15.4	-0.4	3.9	3.7	-2.1	0.9	-0.8	-0.9	3.4	0.9
Nervous feelings	1.0	1.9	8.5	0.6	-2.5	0.1	0.8	1.0	-0.7	-0.4	0.4	-2.9
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	6.6	-1.3	-0.8	-0.9	0.8	-0.9	0.0	-0.2	0.6	-2.6
Hearing difficulty/problems with background noise	2.3	3.6	9.7	-1.8	-1.4	-1.8	3.0	-0.8	3.1	2.2	0.2	0.8
Hair/balding pattern: Pattern 2	2.2	2.8	6.2	-0.9	-1.6	-1.6	2.5	-1.0	1.6	1.8	-1.0	2.4
Had menopause	0.7	0.9	1.8	-0.0	-0.7	-1.1	1.3	-0.0	1.4	1.2	-1.1	-0.2
Had other major operations	0.5	0.6	1.8	0.3	0.8	-1.2	0.4	0.2	1.3	0.9	-0.7	0.3
Forced vital capacity (FVC)	1.2	4.7	8.1	1.7	0.2	2.7	-2.7	1.9	-2.4	-2.3	2.8	-1.7
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.6	13.1	0.9	-0.7	1.8	-2.0	1.3	-1.4	-1.5	2.2	-3.6
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.1	-1.4	-0.1	-0.8	0.7	-1.1	0.8	0.7	-0.7	-0.2
Qualifications: None of the above	1.0	2.1	4.5	1.5	-2.1	-1.9	1.0	0.5	-0.1	0.2	-2.1	-1.8
Financial difficulties in last 2 years	2.4	3.2	7.3	0.2	-1.0	-2.3	2.7	-0.3	2.6	2.3	-1.5	0.4
Mouth/teeth dental problems	0.3	0.4	1.5	-0.1	-1.2	-0.9	-0.2	0.0	-1.0	-0.7	-0.0	-0.3
Heart attack	0.4	0.5	2.7	-0.4	0.3	0.8	-0.9	0.1	-0.3	-0.4	0.2	-1.6
Allergy	1.6	3.7	10.6	1.2	-2.0	-0.8	-1.2	0.8	-2.5	-2.0	-1.9	-3.3
Pain all over the body in last month	0.7	0.7	1.9	-0.7	0.4	-0.7	-0.2	-1.2	-0.5	-0.4	-1.4	-1.3
Diabetes (self-reported)	0.7	1.1	4.8	0.6	2.2	0.6	-0.9	0.8	-0.5	-1.0	-0.1	-1.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	5.2	0.4	-0.3	-0.1	0.6	0.4	1.6	1.3	0.2	2.3
Medication: Ramipril	0.3	0.4	1.2	0.1	1.1	1.0	-0.8	-0.3	-0.2	-0.4	0.1	-0.9
Medication: Simvastatin	1.2	1.7	4.0	1.0	-1.9	-1.4	1.1	0.4	1.1	0.9	-2.0	-1.1
Fluid intelligence score	0.2	0.4	0.9	-0.4	-0.6	-0.1	-0.7	0.1	-0.8	-0.9	0.9	-0.6
Illnesses of siblings	1.6	2.3	6.7	-0.6	-1.5	-1.4	1.8	-0.7	1.4	1.6	-1.2	2.6
Neuroticism score	0.7	1.5	5.2	-0.8	-1.7	-1.5	1.2	-0.8	0.0	0.2	0.5	-2.3
Weight	1.0	4.8	22.8	0.3	-0.3	0.5	-2.6	0.5	-2.0	-3.0	0.5	-4.8
Impedance of arm (right)	0.3	1.4	4.9	0.5	-1.6	-1.4	1.0	0.1	-0.7	-0.0	-2.2	1.4
Arm fat percentage (right)	2.0	7.9	38.0	0.7	-1.4	-0.6	-2.7	0.1	-2.9	-3.6	-1.3	-6.2
Trunk fat-free mass	1.0	5.8	15.9	-0.3	2.0	3.0	-3.1	0.8	-1.4	-2.3	4.0	-2.3
Hip circumference	0.4	1.9	10.9	-0.1	-0.7	-0.7	-0.9	0.2	-1.0	-1.7	-0.4	-3.3
Time employed in main current job	1.1	1.2	3.2	1.6	0.0	1.5	-0.9	1.8	-0.5	-0.6	1.2	-0.3
Alcohol intake versus 10 years previously	1.0	1.5	4.7	0.6	1.2	1.0	-2.2	0.3	-1.5	-1.5	-0.5	-0.8
Father’s age at death	1.5	2.0	6.3	-0.9	1.3	-1.0	1.5	-0.4	1.9	1.5	-0.5	2.5
Worrier / anxious feelings	0.7	1.3	7.8	-0.9	-1.0	0.3	0.7	0.0	-0.1	-0.2	2.8	-1.2
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	8.3	-2.0	-1.3	-2.9	1.6	-2.1	0.7	0.2	-0.6	-1.4
Falls in the last year	0.3	0.4	1.0	-0.8	-0.9	-0.4	0.2	-0.5	-0.5	-0.3	0.0	-1.0
Hair/balding pattern: Pattern 3	0.4	0.6	1.5	-1.0	-0.2	0.3	-0.5	-0.9	-0.3	-0.4	1.2	-1.2
Number of live births	0.5	0.7	2.2	0.9	1.5	0.5	-0.1	1.2	0.9	0.4	0.4	0.7
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	3.6	1.2	0.4	1.3	-1.7	1.1	-1.8	-1.6	1.9	-0.4
Pulse rate	0.6	1.0	3.7	-0.2	-0.5	0.2	1.6	-0.5	1.3	1.9	0.3	0.1
Happiness	2.4	2.9	4.9	-1.4	-1.6	-2.2	2.2	-1.5	1.6	1.6	-0.9	1.9
Noisy workplace	0.9	1.1	4.8	0.2	-2.2	-1.0	0.7	-0.2	0.5	0.4	-1.6	-0.9
Qualifications: A levels/AS levels or equivalent	1.1	2.4	10.1	-1.1	0.8	-0.2	1.4	-0.7	1.7	1.8	0.9	3.2
Serious illness, injury or assault of a close relative in last 2 years	2.2	2.5	6.8	1.5	2.6	0.3	0.6	1.5	2.0	1.4	0.6	2.2
Mouth/teeth dental problems: Dentures	0.3	0.6	3.1	0.5	-0.8	0.0	0.2	-0.3	0.3	0.4	-1.8	-0.8
Asthma	0.5	0.9	2.7	0.2	1.1	1.6	-1.6	0.2	-0.3	-0.7	0.8	-0.8
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.3	2.8	-0.3	0.8	-0.8	1.6	-0.5	1.4	1.7	-1.1	1.5
Medication: Cholesterol lowering	1.0	1.5	7.6	1.3	-2.8	-0.8	-0.0	0.9	-0.0	-0.4	-1.3	-0.9
Depression (self-reported)	0.4	0.4	0.9	0.3	0.4	-0.5	0.9	0.4	1.0	0.9	0.8	-0.1
Medication: Lansoprazole	1.1	1.2	4.4	-1.5	0.9	0.7	-0.4	-0.8	-0.0	-0.4	2.1	-1.4
Prospective memory result	0.2	0.2	0.7	-0.3	-0.3	0.2	-0.3	-0.3	-0.8	-0.4	-0.6	-0.7
Lung cancer (father)	0.1	0.1	0.3	-0.5	0.0	-0.1	-0.6	-0.5	-0.3	-0.2	0.5	-0.2
Illnesses of mother	0.8	0.9	2.0	-1.4	0.0	0.1	1.2	-1.3	1.0	1.2	0.2	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	4.7	0.3	-0.0	1.9	-1.9	0.5	-2.0	-1.8	2.2	-0.5
Pulse wave Arterial Stiffness index	0.5	0.5	1.8	0.3	-1.3	-0.4	1.1	0.2	0.9	0.8	-0.3	0.6
Impedance of arm (left)	0.6	2.7	6.5	0.3	-2.0	-2.2	1.9	-0.3	0.3	0.9	-2.5	2.1
Arm fat mass (right)	1.6	6.8	33.2	0.5	-0.8	-0.1	-2.9	0.2	-2.6	-3.4	-0.5	-5.8
Trunk predicted mass	1.0	5.8	15.5	-0.2	1.9	3.1	-3.1	0.9	-1.4	-2.3	3.9	-2.4
Standing height	0.1	1.1	3.3	0.2	-0.1	1.1	-0.8	1.1	-0.4	-0.8	1.8	1.6
Length of working week for main job	1.8	2.0	6.8	0.2	-2.2	1.1	-1.1	-0.3	-1.6	-1.2	-0.2	-2.6
Exposure to tobacco smoke at home	1.7	1.9	4.6	0.5	-1.9	-1.4	1.3	-0.2	1.2	1.2	-2.2	-1.6
Breastfed as a baby	3.6	4.5	8.3	2.7	1.6	2.7	-2.3	2.9	-2.1	-1.7	1.5	-0.4
Tense / ‘highly strung’	0.7	1.2	2.4	-1.0	-1.5	-0.3	0.2	-0.5	-1.2	-1.1	1.4	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.9	0.2	-0.3	0.2	0.7	0.7	1.4	1.0	0.6	0.6
Hair/balding pattern: Pattern 4	1.7	4.1	12.5	2.5	-0.8	-0.3	-0.6	2.2	-2.6	-2.1	-1.1	-3.5
Birth weight of first child	0.7	1.3	3.3	0.8	-0.7	-0.9	1.8	0.7	1.2	1.1	-1.5	1.2
Peak expiratory flow (PEF)	0.3	0.8	1.3	1.0	-0.4	0.2	-1.1	1.1	-1.0	-1.1	0.9	-0.4
Pulse wave reflection index	1.4	1.8	3.8	-0.4	-1.0	-1.2	1.9	-0.5	1.4	1.6	-1.5	1.5
Ever highly irritable/argumentative for 2 days	1.0	1.3	3.8	-0.6	0.3	-1.9	1.5	0.0	1.3	1.1	-0.7	1.1
Loud music exposure frequency	1.1	1.3	2.6	-0.9	-1.2	-1.6	1.5	-0.7	1.4	1.2	-0.1	-0.3
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.9	-0.9	0.7	-0.4	0.8	-0.7	1.3	1.2	0.9	2.0
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	5.3	-1.1	1.5	1.7	-0.9	-0.6	-0.5	-0.8	2.3	-0.4
Blood clot in the leg (DVT)	0.9	1.1	2.9	-0.9	1.7	1.5	-0.3	-1.0	0.7	0.5	1.5	0.4
Medication: Paracetamol	1.5	2.5	7.1	0.9	0.2	-0.7	1.8	0.8	2.2	2.2	-0.1	2.7
Headache pain in last month	1.5	2.5	4.0	1.6	1.4	0.2	1.8	1.8	1.4	1.9	1.6	2.0
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	5.9	-0.5	2.2	0.9	0.1	-0.7	0.3	0.5	1.0	2.4
Glaucoma (self-reported)	2.4	2.8	6.3	-0.3	-1.4	-1.9	2.1	-0.8	1.9	1.8	-1.4	2.5
Gout (self-reported)	1.6	2.2	4.6	1.1	0.9	0.7	-1.8	1.0	-2.1	-2.1	0.0	-2.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.4	-1.0	-0.4	-0.7	0.9	-0.6	1.2	1.0	0.1	-0.8
Medication: Amlodipine	0.8	1.2	4.3	0.2	0.0	0.2	-1.2	0.5	-1.5	-1.6	-0.1	-2.1
Medication: Ventolin 100micrograms inhaler	0.9	1.1	2.1	-0.6	0.1	1.4	-1.4	-0.3	-1.4	-1.5	0.5	-1.1
Birth weight	1.6	3.5	15.8	1.3	-1.7	0.3	-1.2	0.9	-2.3	-1.9	-0.4	-4.0
Chronic bronchitis/emphysema (mother)	1.0	1.1	2.5	-0.0	-1.1	-1.6	1.1	-0.3	1.5	1.0	-1.3	0.5
High blood pressure (siblings)	1.9	2.8	13.6	0.9	0.5	0.7	-1.7	0.7	-1.5	-1.7	1.1	-3.7
Forced vital capacity (FVC), Best measure	1.2	4.3	8.4	0.6	-0.7	2.9	-2.7	1.1	-2.6	-2.4	2.6	-1.4
Body fat percentage	1.3	5.3	17.9	1.0	-3.0	-2.6	-0.2	0.0	-0.9	-1.4	-3.1	-4.2
Leg fat percentage (right)	1.4	5.0	11.5	1.6	-3.4	-3.4	1.2	0.7	0.7	0.2	-3.4	-2.3
Arm fat-free mass (right)	0.4	2.1	5.9	-0.7	1.2	1.4	-1.8	0.0	-0.4	-1.2	2.4	-2.2
Exposure to tobacco smoke outside home	2.0	2.6	7.3	0.3	-0.2	-2.6	2.1	-0.3	1.1	1.1	-2.7	-1.6
Comparative body size at age 10	6.3	17.3	53.1	-0.1	0.1	2.9	-5.0	0.9	-5.5	-5.7	2.2	-7.3
Number of full brothers	2.6	3.2	5.6	2.4	0.9	-2.0	1.9	1.7	1.8	1.9	-1.8	1.6
Worry too long after embarrassment	2.8	4.7	8.7	-2.3	-2.8	-3.0	2.2	-2.6	0.7	0.6	-0.6	-2.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	4.8	-0.0	-2.2	-0.2	-0.7	-0.1	-1.0	-1.0	-0.6	-0.5
Wheeze or whistling in the chest in last year	0.5	0.9	3.3	-0.2	1.5	1.8	-0.3	0.5	0.5	0.3	1.4	-0.1
Number of children fathered	0.8	0.9	2.6	0.6	0.5	0.9	-1.6	0.5	-1.2	-1.4	0.4	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.8	0.3	0.2	0.4	0.6	0.9	-0.2	0.4	0.7	0.2
Age at first live birth	2.0	3.5	6.9	-1.8	0.5	2.6	-2.4	-1.1	-2.0	-1.9	2.6	0.1
Pulse wave peak to peak time	0.3	0.3	1.2	-0.2	1.1	0.2	-0.9	-0.2	-0.6	-0.6	0.2	-0.2
Health satisfaction	0.8	1.0	4.2	-1.3	-0.3	-0.7	-0.3	-1.3	-0.4	-0.8	0.0	-2.1
Shortness of breath walking on level ground	0.5	0.6	1.6	-0.2	-1.0	-1.1	0.2	-0.4	0.5	0.1	-0.9	-1.2
Qualifications: College or University degree	0.9	2.7	8.2	-1.4	2.9	1.9	-1.2	-0.6	-0.9	-0.8	0.9	2.5
Eye problems/disorders: None of the above	1.4	1.6	3.8	1.3	-0.6	0.8	-1.1	2.0	-1.2	-1.2	0.7	-1.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.5	-0.8	-0.7	-0.8	0.1	-0.8	0.3	0.2	-1.2	-1.1
Emphysema/chronic bronchitis	0.7	0.8	2.8	-0.4	-1.1	-1.0	0.2	-0.8	0.1	-0.1	-1.1	-1.7
Medication for pain relief, constipation, heartburn	0.8	1.3	3.2	-1.0	-0.5	-0.3	-1.4	-0.9	-1.5	-1.8	0.1	-1.5
Neck or shoulder pain in last month	1.7	2.4	5.4	2.2	-0.7	0.8	1.4	2.3	2.0	1.8	1.0	0.3
Medication: Blood pressure	1.0	1.7	8.8	-0.8	-1.5	-0.3	-0.6	-0.5	-1.0	-1.1	-0.6	-3.0
Angina (self-reported)	1.5	2.0	3.3	1.5	-0.4	1.4	-1.7	1.5	-1.8	-1.8	0.1	-1.4
Migraine (self-reported)	1.1	1.4	5.7	0.3	-0.1	-0.9	2.4	-0.5	1.5	1.8	-0.2	0.7
Medication: Ibuprofen	1.3	1.5	2.6	-0.8	1.1	-1.0	1.6	-1.0	1.4	1.6	-1.1	1.2
Medication: Allopurinol	0.5	0.7	1.5	0.4	1.0	-0.3	-0.8	0.2	-1.1	-1.2	-0.1	-1.2
Medication: Omeprazole	1.6	1.9	4.1	1.5	0.3	-0.4	1.7	1.6	2.0	1.8	-0.3	1.6
Medication: Seretide 50 evohaler	0.9	1.0	2.8	1.5	-1.3	0.8	0.6	1.7	0.9	0.7	-0.2	0.4
Mean time to correctly identify matches	0.4	0.7	1.8	-0.8	0.7	0.6	-1.3	-0.8	-0.8	-1.2	0.3	-0.4
Heart disease (mother)	1.6	2.0	6.8	2.6	-1.2	-0.3	-0.4	2.6	-0.6	-0.5	-1.0	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	3.5	1.7	-1.6	-0.4	-0.3	1.9	0.2	-0.1	-0.3	-0.8
Whole body fat mass	1.1	4.6	22.1	0.7	-2.1	-1.4	-1.4	0.3	-1.5	-2.3	-1.7	-4.7
Leg fat mass (right)	0.8	3.2	14.1	1.0	-2.1	-1.8	-0.5	0.5	-0.4	-1.3	-1.8	-3.8
Arm predicted mass (right)	0.4	2.1	6.1	-0.3	1.0	1.4	-1.8	0.3	-0.5	-1.3	2.5	-2.2
Pulse rate, automated reading	0.7	2.1	4.4	-0.6	-2.1	-1.3	2.0	-1.2	1.5	1.7	-1.2	-1.0
Alcohol intake frequency.	1.5	3.6	14.1	0.9	-0.8	-3.1	1.8	-0.1	1.3	1.3	-3.8	-0.1
Comparative height size at age 10	0.5	2.8	5.6	0.9	0.7	2.2	-2.2	1.1	-1.4	-1.8	2.4	-1.4
Number of full sisters	2.3	2.8	5.2	0.2	-1.1	-2.3	2.1	-0.1	2.2	2.1	-2.2	0.7
Suffer from ‘nerves’	1.6	2.5	6.8	1.8	-1.0	0.6	-0.8	2.0	-1.8	-1.6	1.1	-2.6
Overall health rating	1.5	3.1	7.8	-1.5	-2.1	-2.8	1.6	-1.8	0.9	0.3	-1.3	-2.4
Chest pain or discomfort	0.2	0.2	1.6	0.2	0.2	1.3	-0.4	0.1	0.4	0.0	-0.2	-0.4
Had major operations	2.6	3.1	10.7	-0.2	-1.5	1.6	-2.0	-0.1	-1.8	-2.2	0.3	-3.3
Age at last live birth	1.2	1.8	3.3	-1.3	1.8	1.5	-1.4	-0.9	-1.0	-0.8	1.7	1.2
Family relationship satisfaction	3.4	4.1	9.6	-2.6	-2.0	-2.6	1.3	-3.1	0.8	0.8	-2.4	1.3
Leg pain on walking	0.8	1.0	2.4	1.3	0.2	0.1	-1.1	1.2	-1.6	-1.4	-0.5	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	2.5	0.6	-1.0	-1.3	0.8	0.3	0.5	0.6	-1.6	-0.3
Commuting to job workplace: Car/motor vehicle	2.4	2.7	6.2	2.2	-1.5	0.7	-1.3	2.5	-1.7	-1.7	-0.5	-1.7
Illness, injury, bereavement, stress in last 2 years	2.5	3.1	7.0	-1.9	-2.6	0.7	-1.4	-1.5	-2.1	-1.7	1.2	-1.9
Medication: Aspirin	2.2	2.9	5.9	0.8	0.8	1.7	-2.2	1.1	-2.4	-2.1	0.4	-2.3
Supplements: Vitamin C	1.1	1.3	6.3	-0.0	1.0	1.5	-0.9	-0.1	-0.7	-0.6	0.8	2.5
Knee pain experienced in last month	1.9	3.0	4.9	1.1	1.9	1.8	-1.7	1.1	-1.4	-1.9	2.0	-2.2
Hypertension (Self-reported)	1.5	4.2	23.5	0.5	-1.1	0.7	-1.3	0.9	-2.2	-2.2	0.7	-4.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.6	1.6	0.4	-0.4	-1.3	1.1	-0.0	1.1	0.8	-0.8	0.1
Illnesses of father: Heart disease	2.0	2.7	5.1	-1.6	0.2	2.3	-2.1	-0.8	-1.2	-1.8	2.0	-1.8
Illnesses of siblings: Diabetes	0.8	1.0	3.5	-1.5	0.6	-0.8	0.8	-1.9	0.5	0.6	-0.9	-0.3
Smoking status: Previous	0.7	1.0	2.0	1.1	1.4	0.8	-0.9	1.3	0.6	-0.1	0.7	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	5.1	1.9	-0.9	-0.3	0.7	2.3	0.8	0.9	1.0	1.9
Whole body fat-free mass	1.2	6.9	13.8	-0.2	1.9	3.0	-3.5	0.7	-2.0	-2.8	3.7	-3.4
Leg fat-free mass (right)	1.8	9.4	21.5	-0.5	2.3	3.0	-4.1	0.2	-2.9	-3.7	3.2	-4.6
Arm fat percentage (left)	1.7	6.8	35.2	0.6	-1.5	-0.9	-2.3	-0.2	-2.5	-3.1	-1.4	-5.9
Average weekly red wine intake	1.7	2.5	7.7	0.6	1.4	2.8	-1.6	1.7	-1.1	-1.0	2.4	-0.1
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.1	0.9	-0.4	0.5	-0.2	1.0	-0.1	0.3	-0.2	0.6
Mood swings	0.4	0.7	3.0	-0.2	-1.7	-0.3	0.4	-0.0	-0.5	-0.5	0.7	-1.5
Loneliness, isolation	0.1	0.2	0.5	0.2	-0.3	-0.4	0.7	-0.2	-0.1	0.1	-0.4	-0.7
Long-standing illness, disability or infirmity	0.5	0.8	3.7	-0.8	0.1	-0.5	-0.5	-0.8	-0.7	-0.8	-0.6	-1.9
Ever had bowel cancer screening	2.6	3.1	9.3	-1.1	-1.8	1.0	-2.0	-0.6	-1.8	-2.2	0.4	-3.0
Diabetes diagnosed by doctor	0.3	0.6	4.1	0.3	2.0	0.1	0.1	0.3	0.6	0.2	-0.5	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.3	0.8	-0.1	1.1	-0.3	1.0	0.5	0.5	0.6	-0.1
Friendships satisfaction	0.7	0.8	1.3	-1.0	-0.8	-0.9	1.1	-0.9	0.5	0.5	-1.1	1.1
Qualifications: nursing, teaching	1.7	2.7	5.0	-1.3	1.1	0.2	1.9	-0.6	2.2	2.1	1.8	2.1
Commuting to job workplace: Walk	3.7	4.0	10.1	-1.7	0.2	-2.6	3.2	-1.8	2.1	2.4	-1.2	1.0
Eye problems/disorders: Cataract	0.6	0.7	2.7	-1.1	0.3	-0.7	0.2	-1.6	0.4	0.4	-1.0	-0.1
Mouth/teeth dental problems: Mouth ulcers	1.6	2.6	7.6	0.7	0.5	0.8	2.4	0.7	2.6	2.8	0.4	1.2
Medication for cholesterol	1.0	1.5	5.1	-1.3	0.5	0.7	0.9	-0.8	0.9	1.1	1.6	2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	6.1	1.9	0.1	1.9	-0.7	2.5	-0.1	-0.5	1.8	-0.2
Back pain experienced in last month	1.7	2.5	5.2	2.0	1.2	-0.8	1.2	1.4	2.3	1.9	-0.9	1.9
Mineral and other dietary supplements	0.3	0.4	1.2	-1.0	0.1	0.4	-0.2	-1.1	0.5	0.2	-0.8	0.2
Breast cancer (self-reported)	0.8	1.0	3.4	0.4	0.3	-1.5	-0.5	0.0	-0.6	-0.9	-1.2	-1.8
Asthma (self-reported)	0.4	0.8	2.9	0.4	1.3	1.7	-1.4	0.3	-0.1	-0.4	0.8	-0.4
Osteoporosis (self-reported)	0.3	0.3	2.1	0.3	0.6	0.5	0.0	-0.0	0.0	-0.1	-1.4	0.6
Osteoarthritis (self-reported)	0.4	0.6	2.0	-0.7	1.4	-0.1	-0.8	-0.7	-0.2	-0.5	1.0	0.4
Medication: Aspirin	2.8	3.6	7.5	0.4	0.8	1.9	-2.6	0.6	-2.7	-2.6	0.6	-2.6
Medication: Gliclazide	2.0	2.3	3.9	1.9	2.0	0.6	-1.3	1.4	-1.8	-1.9	0.4	-1.4
Illnesses of father: None of the above (group 1)	0.5	0.6	1.6	0.8	-0.6	-1.3	0.8	0.3	0.4	0.6	-0.9	0.9
Smoking status: Current	4.1	6.5	13.1	0.4	0.6	-2.9	3.0	-0.1	3.6	3.5	-1.6	3.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.4	7.4	-0.9	-1.3	1.3	-2.0	-1.1	-2.6	-2.4	1.2	-2.7
Whole body water mass	1.2	6.7	12.4	-0.2	2.0	2.9	-3.4	0.6	-2.0	-2.8	3.5	-3.4
Leg predicted mass (right)	1.8	9.7	22.1	-0.4	2.4	3.1	-4.1	0.3	-2.9	-3.7	3.3	-4.7
Arm fat mass (left)	1.4	5.6	28.6	0.5	-0.7	-0.3	-2.6	0.1	-2.2	-3.0	-0.7	-5.4
Number of self-reported non-cancer illnesses	0.2	0.3	0.9	-0.1	-0.2	0.2	-0.1	0.3	0.9	0.2	0.7	-1.0
Average weekly champagne plus white wine intake	1.5	2.1	5.6	-0.0	1.7	1.9	-1.7	0.7	-1.2	-1.4	2.4	-0.5
Miserableness	0.3	0.5	1.3	0.4	-0.2	-1.1	1.1	0.5	0.6	0.6	-0.1	-0.6
Guilty feelings	1.5	2.2	6.3	-2.0	-2.1	-0.7	0.6	-2.1	0.2	-0.1	0.2	-2.5
Wears glasses or contact lenses	0.2	0.3	0.8	-0.6	-0.5	-0.3	0.3	-0.8	0.2	-0.3	-0.2	-0.9
Ever taken oral contraceptive pill	0.2	0.3	1.7	-0.1	1.3	0.1	0.0	0.1	0.2	0.2	0.5	0.7
Hearing aid user	0.7	0.8	3.6	0.4	-1.9	0.5	-0.1	0.4	-1.0	-1.0	0.5	-0.7
Mother’s age at death	0.2	0.3	1.1	-0.0	0.4	1.0	-0.1	0.3	0.1	0.1	1.1	0.6
Financial situation satisfaction	1.1	1.4	3.4	-1.5	1.1	-0.9	0.9	-1.9	1.0	1.1	-0.8	1.1
Tinnitus: Yes, now most or all of the time	0.6	0.7	3.2	0.1	-0.1	0.8	0.9	0.8	0.7	0.8	1.8	-0.3
Commuting to job workplace: Public transport	1.5	1.8	6.2	-2.5	1.0	-1.1	0.6	-2.4	0.8	0.7	0.4	1.0
Eye problems/disorders: Glaucoma	1.4	1.6	5.1	0.1	-0.0	-1.0	1.6	-0.2	1.6	1.6	-0.8	2.3
Medication: Blood pressure	0.8	1.6	7.0	-0.9	0.9	0.7	-1.3	-0.8	-0.9	-1.3	0.3	-2.6
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.4	0.0	-1.1	-1.1	0.5	0.0	1.0	0.5	-1.2	0.7
Supplements: Fish oil (including cod liver oil)	0.3	0.3	0.8	0.8	-0.7	-0.6	0.9	0.5	0.2	0.7	0.0	-0.0
High cholesterol (Self-reported)	0.6	1.1	2.3	0.9	-0.9	-1.4	0.9	0.5	1.3	1.0	-1.5	0.7
Medication: Bendroflumethiazide	0.5	0.8	2.2	1.5	0.4	-0.2	-0.6	1.2	-0.7	-0.6	-0.4	-1.5
Medication: Paracetamol	0.6	0.9	2.7	0.4	0.3	-0.6	0.9	0.4	1.5	1.3	0.0	1.6
Medication: Lisinopril	0.3	0.4	0.8	-0.9	-0.6	-0.7	0.6	-0.5	0.5	0.3	0.0	-0.8
Medication: Atorvastatin	0.6	0.7	2.8	0.1	-0.7	-1.6	0.3	-0.3	0.3	-0.2	-1.7	0.5
Illnesses of father: High blood pressure	1.7	2.2	6.9	-1.4	-2.6	0.4	-1.1	-1.3	-1.5	-1.7	0.1	-1.5
Alcohol drinker status: Never	0.9	1.1	3.5	0.7	-0.0	-1.1	-0.5	0.2	-1.5	-0.9	-1.9	-0.9
Ever smoked	1.5	2.6	11.8	0.8	1.7	-0.2	0.6	0.7	2.0	1.6	0.7	3.4
Basal metabolic rate	1.0	5.7	13.2	0.0	1.4	2.3	-3.2	0.7	-2.0	-2.9	2.8	-3.6
Leg fat percentage (left)	1.4	5.2	12.8	1.2	-3.3	-3.6	1.3	0.4	0.8	0.2	-3.6	-2.7
Arm fat-free mass (left)	0.6	3.0	7.2	0.1	1.1	1.8	-2.3	0.8	-1.0	-1.8	2.3	-2.7
Number of operations (self-reported)	0.8	1.2	6.2	0.6	-0.8	0.8	-1.1	0.9	-0.4	-1.0	0.1	-2.5
Average weekly beer plus cider intake	0.7	1.0	3.9	1.0	-0.0	-2.0	0.2	0.2	-0.3	-0.1	-1.9	-0.7
Irritability	0.1	0.2	0.7	0.3	0.0	-0.7	0.6	0.4	0.2	0.6	0.1	0.8
Risk taking	1.7	2.5	8.6	0.8	2.0	-0.3	1.4	0.9	1.6	2.0	-0.2	2.9
Ever had prostate specific antigen (PSA) test	1.4	1.6	4.2	-1.2	-1.0	2.0	-0.9	-0.5	-0.3	-0.8	2.0	-1.5
Fractured/broken bones in last 5 years	0.5	0.6	3.1	-0.9	1.8	0.9	-0.3	-0.4	0.3	0.3	0.3	0.2
Age started oral contraceptive pill	1.2	1.5	5.1	-1.2	-1.4	-2.3	1.0	-1.2	0.3	0.3	-1.5	-0.7
Diastolic blood pressure, automated reading	3.2	9.9	33.2	2.6	-2.3	1.5	-2.8	2.2	-3.8	-3.6	0.4	-5.8
Ever depressed for a whole week	0.8	1.0	3.4	-0.3	0.2	-0.7	1.1	0.1	1.9	1.4	-0.4	1.1
Unable to work because of sickness or disability	0.8	1.0	5.2	0.0	-1.0	-2.3	0.9	0.7	0.9	0.7	-0.7	-0.5
Commuting to job workplace: Cycle	2.0	2.4	8.1	0.3	2.5	2.8	-0.3	0.5	0.7	0.7	1.7	1.6
Myopia	0.5	0.7	2.2	-1.5	-0.2	-1.5	-0.3	-1.1	-0.1	-0.7	-0.3	-0.4
Vascular/heart problems diagnosed by doctor	1.9	5.1	24.4	-0.9	0.2	-1.4	1.9	-1.5	2.5	2.4	-1.0	4.9
Cholesterol lowering medication	0.4	0.7	2.2	1.0	0.5	-1.1	0.3	0.6	0.7	0.5	-1.5	-0.5
Medication: Omeprazole (e.g. Zanprol)	2.6	3.1	8.4	0.8	0.0	-0.9	2.6	1.0	2.9	2.6	-0.3	2.0
Pain experienced in last month	0.9	1.5	3.1	-1.1	-1.8	-0.6	-1.1	-0.8	-1.7	-1.2	-1.4	-0.8
Supplements: Calcium	0.6	0.7	1.5	-0.3	1.1	-0.5	-1.2	-0.4	-0.8	-1.1	0.3	0.7
Basal cell carcinoma (self-reported)	2.0	2.4	6.2	-0.0	0.1	-1.1	1.7	-0.5	2.1	2.4	-0.1	2.5
Heart attack/myocardial infarction (self-reported)	0.4	0.5	3.0	-0.5	0.1	0.6	-0.7	-0.0	-0.3	-0.3	0.0	-1.7
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	3.8	-1.0	2.0	1.4	-0.5	-1.0	0.5	0.3	1.6	0.3
Heart disease (siblings)	0.7	0.8	1.7	-0.8	0.6	1.0	-1.2	-0.8	-0.6	-0.9	0.6	-1.3
Alcohol drinker status: Previous	0.9	1.0	3.4	-0.5	-0.8	-1.4	0.3	-0.9	0.6	0.3	-1.9	-1.1
Pack years of smoking	2.0	2.9	9.1	0.7	-2.1	-2.9	1.6	0.1	0.6	1.1	-3.0	0.1
Impedance of whole body	2.6	13.4	24.4	0.8	-3.8	-4.4	4.6	-0.0	2.7	3.5	-4.6	4.9
Leg fat mass (left)	0.9	3.3	15.5	0.9	-2.2	-1.8	-0.4	0.5	-0.4	-1.2	-1.9	-3.9
Arm predicted mass (left)	0.5	2.5	5.7	-0.0	1.3	1.6	-2.2	0.6	-0.9	-1.7	2.1	-2.4