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chr19:32,209,988-34,959,979

Best TWAS P=1.06e-21 · Best GWAS P=6.48e-20 conditioned to 0.107

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DPY19L3	0.07	0.05	lasso	2	0.06	8.7e-08	-5.21	-5.1	2.9e-07	0.00	0.01	0.99	TRUE
2	CommonMind	Brain Pre-frontal Cortex	PEPD	0.32	0.27	enet	22	0.38	1.2e-49	2.02	6.0	1.4e-09	0.49	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	PEPD	0.30	0.25	lasso	6	0.26	2.5e-21	6.13	5.7	1.0e-08	0.75	1.00	0.00	FALSE
4	GTEx	Breast Mammary Tissue	PEPD	0.16	0.06	lasso	4	0.04	3.5e-03	6.13	6.8	1.5e-11	0.79	0.33	0.64	FALSE
5	GTEx	Colon Transverse	PEPD	0.14	0.16	lasso	2	0.13	1.2e-06	6.13	6.0	1.7e-09	0.74	0.60	0.26	FALSE
6	GTEx	Esophagus Mucosa	PEPD	0.37	0.32	enet	20	0.39	9.5e-28	6.08	8.2	1.8e-16	0.90	0.01	0.99	FALSE
7	GTEx	Muscle Skeletal	PEPD	0.08	0.03	lasso	4	0.04	1.3e-04	-6.67	5.6	2.6e-08	0.54	0.44	0.34	FALSE
8	METSIM	Adipose	CHST8	0.22	0.17	lasso	4	0.17	3.7e-25	6.08	6.3	3.8e-10	0.76	1.00	0.00	FALSE
9	METSIM	Adipose	PEPD	0.19	0.18	lasso	5	0.17	2.3e-24	6.08	6.2	6.9e-10	0.76	1.00	0.00	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PEPD	0.06	0.01	blup	114	0.04	2.6e-04	9.14	8.1	7.4e-16	0.86	0.01	0.97	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	PEPD	0.13	0.06	blup	113	0.10	1.2e-06	5.50	9.6	1.1e-21	0.87	0.01	0.99	TRUE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PEPD	0.04	0.05	blup	113	0.03	1.9e-04	-6.67	6.2	5.1e-10	0.50	0.54	0.19	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	PEPD	0.05	0.03	blup	113	0.05	7.1e-07	6.72	6.0	2.6e-09	0.68	0.06	0.94	FALSE
14	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PEPD	0.16	0.07	lasso	3	0.05	3.1e-03	9.06	8.8	1.4e-18	0.98	0.00	0.98	FALSE
15	The Cancer Genome Atlas	Stomach Adenocarcinoma	PEPD	0.08	0.02	blup	113	0.02	7.0e-03	-0.79	5.2	2.2e-07	0.61	0.06	0.27	FALSE