Best TWAS P=3.46e-08 · Best GWAS P=9.75e-09 conditioned to 0.0922
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | AC015971.2 | 0.09 | 0.03 | lasso | 6 | 0.05 | 0.00091 | 5.7 | -5.5 | 3.5e-08 | -0.92 | 0.01 | 0.95 | TRUE |
2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | RNF103 | 0.06 | 0.02 | blup | 42 | 0.02 | 0.02420 | -4.2 | 5.2 | 1.8e-07 | 0.84 | 0.02 | 0.44 | FALSE |