Best TWAS P=3.59e-09 · Best GWAS P=3.66e-09 conditioned to 0.0109
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | AFF3 | 0.14 | 0.06 | lasso | 5 | 0.07 | 1.2e-04 | -5.9 | -5.9 | 3.6e-09 | 0.69 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | LONRF2 | 0.05 | 0.03 | lasso | 2 | 0.02 | 9.3e-03 | 4.8 | -5.3 | 9.3e-08 | 0.42 | 0.17 | 0.53 | FALSE |
| 3 | GTEx | Thyroid | CHST10 | 0.05 | 0.05 | lasso | 5 | 0.03 | 2.6e-03 | -4.6 | -5.4 | 5.9e-08 | 0.39 | 0.33 | 0.49 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LONRF2 | 0.06 | 0.04 | blup | 69 | 0.04 | 3.4e-05 | 4.5 | -5.4 | 5.3e-08 | 0.53 | 0.36 | 0.62 | FALSE |