Best TWAS P=1.86e-08 · Best GWAS P=2.91e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | RERE | 0.13 | 0.16 | lasso | 3 | 0.16 | 7.2e-11 | -5.3 | 5.3 | 1.4e-07 | -0.98 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Esophagus Mucosa | RP5-1115A15.1 | 0.06 | 0.06 | lasso | 4 | 0.05 | 3.0e-04 | -5.3 | 5.4 | 7.3e-08 | -0.95 | 0.01 | 0.97 | FALSE |
| 3 | GTEx | Lung | RP5-1115A15.1 | 0.05 | 0.08 | lasso | 1 | 0.07 | 1.0e-05 | -5.5 | 5.5 | 4.9e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Thyroid | RP5-1115A15.1 | 0.09 | 0.12 | lasso | 2 | 0.09 | 1.5e-07 | -5.5 | 5.5 | 4.7e-08 | -0.99 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Whole Blood | RERE | 0.19 | 0.15 | lasso | 4 | 0.13 | 2.7e-12 | -5.3 | 5.3 | 9.7e-08 | -0.98 | 0.00 | 1.00 | FALSE |
| 6 | YFS | Blood | RERE | 0.09 | 0.15 | lasso | 4 | 0.16 | 5.7e-49 | -5.5 | 5.6 | 1.9e-08 | -0.98 | 0.00 | 1.00 | TRUE |
| 7 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RERE | 0.02 | 0.03 | lasso | 2 | 0.03 | 4.7e-07 | -5.5 | 5.4 | 5.9e-08 | -0.98 | 0.00 | 1.00 | FALSE |
| 8 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | RERE | 0.22 | 0.04 | lasso | 10 | 0.08 | 4.1e-04 | -5.3 | 5.5 | 4.4e-08 | -0.90 | 0.01 | 0.96 | FALSE |