Best TWAS P=4.39e-11 · Best GWAS P=5.6e-13 conditioned to 0.000174
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 1.3e-03 | 6.3 | -6.4 | 1.4e-10 | -0.85 | 0.17 | 0.81 | TRUE |
| 2 | YFS | Blood | TAL1 | 0.03 | 0.02 | bslmm | 402 | 0.02 | 2.6e-06 | 6.7 | -6.6 | 4.4e-11 | 0.03 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | TAL1 | 0.03 | 0.02 | blup | 75 | 0.02 | 9.2e-03 | 5.7 | 5.5 | 4.9e-08 | 0.00 | 0.02 | 0.82 | FALSE |