Best TWAS P=9.97e-09 · Best GWAS P=6.92e-10 conditioned to 0.000394
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | LDB3 | 0.20 | 0.00 | enet | 56 | 0.02 | 2.3e-02 | 3.2 | 5.2 | 2.2e-07 | 0.29 | 0.11 | 0.28 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GRID1 | 0.09 | 0.04 | lasso | 9 | 0.03 | 2.1e-07 | -5.6 | -5.7 | 1.0e-08 | -0.43 | 0.11 | 0.89 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | GRID1 | 0.07 | 0.03 | lasso | 4 | 0.02 | 9.7e-04 | -5.6 | -5.4 | 5.3e-08 | -0.37 | 0.11 | 0.79 | FALSE |