Best TWAS P=1.37e-10 · Best GWAS P=1.96e-07 conditioned to 0.365
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | MARCH5 | 0.05 | 0.02 | lasso | 3 | 0.01 | 0.056 | 5.2 | -5.3 | 1.4e-07 | -0.81 | 0.03 | 0.89 | FALSE |
2 | GTEx | Whole Blood | CPEB3 | 0.04 | 0.01 | lasso | 4 | 0.02 | 0.012 | 5.2 | 6.4 | 1.4e-10 | 0.88 | 0.04 | 0.72 | TRUE |