[Hub]/) : Traits : Arm fat mass (right) :

chr1:752,566-3,172,702

Best TWAS P=2.08e-11 · Best GWAS P=9.14e-09 conditioned to 0.0449

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP1-283E3.4 0.65 0.14 lasso 9 0.33 5.1e-28 -3.3 -5.9 4.0e-09 0.00 0.88 0.03 FALSE
2 GTEx Adipose Visceral Omentum RP1-283E3.4 0.26 0.05 enet 25 0.16 1.5e-08 -3.3 -5.9 4.6e-09 -0.02 0.14 0.09 FALSE
3 GTEx Artery Aorta RP1-283E3.4 0.60 0.12 lasso 9 0.27 3.2e-15 -3.3 -5.3 9.4e-08 -0.01 0.49 0.05 FALSE
4 GTEx Artery Tibial RP1-283E3.4 0.66 0.09 lasso 6 0.38 4.9e-31 -3.3 -5.5 3.0e-08 0.01 0.88 0.03 FALSE
5 GTEx Artery Tibial RP11-345P4.10 0.61 0.10 lasso 10 0.36 3.1e-29 -3.1 5.3 1.1e-07 0.01 0.90 0.01 FALSE
6 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 -5.1 5.6 2.1e-08 -0.01 0.02 0.54 TRUE
7 GTEx Cells Transformed fibroblasts RP1-283E3.4 0.59 0.13 lasso 8 0.29 3.0e-22 3.4 -6.2 7.3e-10 0.01 0.88 0.03 FALSE
8 GTEx Cells Transformed fibroblasts RP11-345P4.10 0.66 0.17 lasso 13 0.32 7.5e-25 -3.1 5.1 2.7e-07 0.00 0.90 0.01 FALSE
9 GTEx Esophagus Mucosa TMEM52 0.17 0.18 lasso 2 0.20 2.9e-13 -5.2 5.1 3.0e-07 0.02 0.02 0.98 FALSE
10 GTEx Esophagus Mucosa RP1-283E3.4 0.53 0.12 enet 20 0.22 4.1e-15 -3.3 -6.5 6.9e-11 0.02 0.88 0.03 FALSE
11 GTEx Esophagus Muscularis RP1-283E3.4 0.46 0.14 enet 23 0.24 1.6e-14 -3.3 -6.7 2.1e-11 0.01 0.84 0.03 TRUE
12 GTEx Esophagus Muscularis RP3-395M20.12 0.08 0.06 enet 6 0.06 2.3e-04 4.2 -5.6 2.1e-08 0.78 0.01 0.98 TRUE
13 GTEx Heart Atrial Appendage RP11-345P4.10 0.36 0.11 enet 15 0.16 1.1e-07 -3.1 5.5 4.6e-08 -0.01 0.09 0.04 FALSE
14 GTEx Lung RP1-283E3.4 0.58 0.07 lasso 7 0.34 8.8e-27 -3.3 -5.6 2.3e-08 0.02 0.88 0.03 FALSE
15 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 -5.0 5.5 4.9e-08 -0.02 0.04 0.96 FALSE
16 GTEx Muscle Skeletal SLC35E2B 0.35 0.06 lasso 4 0.19 3.2e-18 -3.1 5.7 1.4e-08 0.01 0.88 0.01 FALSE
17 GTEx Muscle Skeletal RP1-283E3.4 0.51 0.12 lasso 6 0.29 2.4e-28 -3.3 -5.4 5.1e-08 0.01 0.88 0.03 FALSE
18 GTEx Muscle Skeletal RP11-345P4.10 0.54 0.06 lasso 7 0.29 4.7e-29 -3.1 5.5 3.8e-08 0.00 0.89 0.02 FALSE
19 GTEx Skin Not Sun Exposed Suprapubic TMEM52 0.19 0.18 lasso 4 0.14 2.6e-08 4.9 5.1 2.8e-07 -0.01 0.03 0.96 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic RP1-283E3.4 0.48 0.12 lasso 5 0.31 1.1e-17 -3.3 -5.9 3.0e-09 0.01 0.40 0.14 FALSE
21 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 5.1 5.3 1.1e-07 -0.01 0.02 0.98 FALSE
22 GTEx Thyroid RP1-283E3.4 0.59 0.04 lasso 10 0.22 3.8e-17 -3.3 -6.2 5.3e-10 0.00 0.65 0.04 FALSE
23 ROSMAP Brain Pre-frontal Cortex MMP23B 0.05 0.04 lasso 2 0.03 1.9e-04 -5.2 -5.2 1.9e-07 0.02 0.02 0.98 FALSE