Best TWAS P=4.57e-10 · Best GWAS P=2.96e-10 conditioned to 5.54e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PRDM4 | 0.07 | 0.08 | lasso | 2 | 0.07 | 5.0e-09 | 6.1 | 6.1 | 1.2e-09 | -0.02 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Whole Blood | PRDM4 | 0.10 | 0.08 | lasso | 5 | 0.05 | 1.8e-05 | 6.1 | -6.2 | 4.6e-10 | 0.02 | 0.03 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ASCL4 | 0.03 | 0.03 | blup | 49 | 0.03 | 2.9e-04 | 6.1 | 5.9 | 4.0e-09 | -0.11 | 0.01 | 0.94 | FALSE |