Best TWAS P=1.59e-08 · Best GWAS P=2.18e-09 conditioned to 0.0163
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | RPS6KA5 | 0.08 | 0.07 | lasso | 2 | 0.06 | 5.3e-05 | -5.4 | 5.5 | 3.4e-08 | -0.89 | 0.06 | 0.92 | FALSE |
2 | GTEx | Spleen | C14orf159 | 0.30 | 0.21 | lasso | 5 | 0.21 | 3.6e-06 | -5.1 | 5.7 | 1.6e-08 | -0.81 | 0.07 | 0.47 | TRUE |