Best TWAS P=1.61e-07 · Best GWAS P=2.19e-08 conditioned to 0.0493
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HSPD1 | 0.08 | 0.09 | lasso | 7 | 0.09 | 2.2e-11 | -5.3 | -5.2 | 1.6e-07 | 0.93 | 0.03 | 0.97 | TRUE |
| 2 | GTEx | Brain Frontal Cortex BA9 | MARS2 | 0.18 | 0.12 | lasso | 2 | 0.07 | 5.1e-03 | -5.2 | 5.2 | 2.4e-07 | -0.91 | 0.06 | 0.62 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RFTN2 | 0.02 | 0.02 | lasso | 2 | 0.01 | 1.1e-03 | -5.3 | -5.1 | 3.1e-07 | 0.91 | 0.01 | 0.96 | FALSE |