Best TWAS P=4.21e-08 · Best GWAS P=3.9e-07 conditioned to 0.487
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue | UBXN7 | 0.20 | 0.00 | enet | 16 | 0.02 | 0.0352 | -4.2 | -5.3 | 1.2e-07 | -0.65 | 0.02 | 0.83 | FALSE |
2 | GTEx | Stomach | SLC51A | 0.13 | 0.06 | enet | 12 | 0.03 | 0.0193 | 4.6 | -5.5 | 4.2e-08 | -0.86 | 0.01 | 0.93 | TRUE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UBXN7 | 0.02 | 0.01 | blup | 45 | 0.02 | 0.0042 | 3.8 | -5.4 | 5.4e-08 | -0.76 | 0.01 | 0.48 | FALSE |
4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | PCYT1A | 0.12 | 0.05 | blup | 68 | 0.06 | 0.0002 | 4.7 | -5.4 | 6.2e-08 | -0.75 | 0.01 | 0.87 | FALSE |