Best TWAS P=1.66e-09 · Best GWAS P=1.33e-07 conditioned to 0.00315
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | HINT1 | 0.10 | 0.07 | enet | 16 | 0.06 | 8.8e-06 | -4.9 | -6.0 | 1.7e-09 | 0.43 | 0.03 | 0.96 | TRUE |
| 2 | GTEx | Artery Tibial | HINT1 | 0.11 | 0.04 | enet | 18 | 0.06 | 1.0e-05 | -4.7 | -5.6 | 2.7e-08 | 0.73 | 0.06 | 0.88 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | HINT1 | 0.10 | 0.06 | lasso | 2 | 0.05 | 2.1e-04 | -4.7 | -5.2 | 2.6e-07 | 0.53 | 0.04 | 0.94 | FALSE |