Best TWAS P=8.7e-09 · Best GWAS P=4e-11 conditioned to 2.38e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FAM114A2 | 0.28 | 0.39 | lasso | 9 | 0.41 | 1.8e-53 | -4.9 | 5.3 | 1.4e-07 | 0.22 | 0.98 | 0.02 | FALSE |
| 2 | NTR | Blood | FAM114A2 | 0.04 | 0.03 | lasso | 10 | 0.02 | 8.9e-08 | -4.9 | 5.1 | 2.7e-07 | 0.18 | 0.98 | 0.02 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | FAM114A2 | 0.05 | 0.06 | lasso | 6 | 0.05 | 6.3e-07 | -5.8 | 5.8 | 8.7e-09 | 0.29 | 0.62 | 0.37 | TRUE |