Best TWAS P=5.11e-16 · Best GWAS P=1.37e-19 conditioned to 4.12e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -5.4 | 6.2 | 4.9e-10 | -0.66 | 0.72 | 0.11 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 5.6 | 8.1 | 5.1e-16 | -0.48 | 0.53 | 0.47 | TRUE |