Best TWAS P=5.4e-08 · Best GWAS P=6.28e-09 conditioned to 0.000121
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GRID1 | 0.09 | 0.04 | lasso | 9 | 0.03 | 2.1e-07 | -5.2 | -5.4 | 5.4e-08 | -0.43 | 0.10 | 0.90 | TRUE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | GRID1 | 0.07 | 0.03 | lasso | 4 | 0.02 | 9.7e-04 | -5.2 | -5.1 | 2.8e-07 | -0.37 | 0.04 | 0.93 | FALSE |