[Hub]/) : Traits : Arm fat mass (right) :

chr11:26,818,083-29,054,545

Best TWAS P=1.96e-25 · Best GWAS P=7.01e-36 conditioned to 3.1e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LIN7C 0.08 0.06 lasso 1 0.04 4.1e-04 10.29 10.3 7.6e-25 0.63 0.74 0.14 FALSE
2 GTEx Brain Putamen basal ganglia BDNF-AS 0.22 0.17 lasso 4 0.13 5.5e-04 -6.90 8.2 2.2e-16 0.33 0.23 0.05 FALSE
3 GTEx Cells Transformed fibroblasts LIN7C 0.26 0.22 lasso 6 0.25 1.4e-18 10.29 8.4 2.8e-17 0.62 1.00 0.00 FALSE
4 GTEx Esophagus Muscularis LIN7C 0.14 0.08 enet 11 0.07 5.4e-05 3.22 7.2 4.5e-13 0.60 0.69 0.16 FALSE
5 GTEx Liver METTL15 0.18 0.05 lasso 3 0.09 1.9e-03 -0.68 -7.7 2.0e-14 -0.68 0.02 0.83 FALSE
6 GTEx Nerve Tibial LIN7C 0.18 0.08 enet 27 0.12 4.2e-09 10.29 6.8 8.5e-12 0.56 0.62 0.35 FALSE
7 GTEx Thyroid LIN7C 0.08 0.04 lasso 4 0.04 6.0e-04 10.29 10.0 2.3e-23 0.69 0.53 0.35 FALSE
8 NTR Blood LIN7C 0.01 0.00 lasso 3 0.01 2.2e-03 10.66 -10.4 2.0e-25 -0.72 0.10 0.80 TRUE
9 ROSMAP Brain Pre-frontal Cortex METTL15 0.04 0.03 blup 364 0.03 4.6e-05 -3.18 -5.7 1.4e-08 -0.19 0.72 0.01 TRUE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma LIN7C 0.04 0.01 lasso 3 0.02 1.0e-02 -1.78 6.1 9.3e-10 0.46 0.02 0.81 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma LIN7C 0.10 0.03 blup 32 0.08 2.8e-05 10.70 8.0 1.5e-15 0.57 0.01 0.96 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LIN7C 0.05 0.02 lasso 3 0.03 2.9e-04 10.68 9.5 1.9e-21 0.63 0.00 0.98 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma LIN7C 0.09 0.12 lasso 2 0.12 2.6e-13 3.32 5.7 1.2e-08 0.52 0.91 0.09 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma BDNFOS 0.03 0.01 blup 83 0.02 1.4e-03 1.69 5.3 1.3e-07 -0.13 0.34 0.02 TRUE
15 The Cancer Genome Atlas Thyroid Carcinoma LIN7C 0.09 0.10 enet 7 0.09 8.1e-09 3.32 5.2 2.3e-07 0.48 0.91 0.08 FALSE