[Hub]/) : Traits : Arm fat mass (right) : ← →

chr11:26,818,083-29,054,545

Best TWAS P=1.96e-25 · Best GWAS P=7.01e-36 conditioned to 3.1e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	LIN7C	0.08	0.06	lasso	1	0.04	4.1e-04	10.29	10.3	7.6e-25	0.63	0.74	0.14	FALSE
2	GTEx	Brain Putamen basal ganglia	BDNF-AS	0.22	0.17	lasso	4	0.13	5.5e-04	-6.90	8.2	2.2e-16	0.33	0.23	0.05	FALSE
3	GTEx	Cells Transformed fibroblasts	LIN7C	0.26	0.22	lasso	6	0.25	1.4e-18	10.29	8.4	2.8e-17	0.62	1.00	0.00	FALSE
4	GTEx	Esophagus Muscularis	LIN7C	0.14	0.08	enet	11	0.07	5.4e-05	3.22	7.2	4.5e-13	0.60	0.69	0.16	FALSE
5	GTEx	Liver	METTL15	0.18	0.05	lasso	3	0.09	1.9e-03	-0.68	-7.7	2.0e-14	-0.68	0.02	0.83	FALSE
6	GTEx	Nerve Tibial	LIN7C	0.18	0.08	enet	27	0.12	4.2e-09	10.29	6.8	8.5e-12	0.56	0.62	0.35	FALSE
7	GTEx	Thyroid	LIN7C	0.08	0.04	lasso	4	0.04	6.0e-04	10.29	10.0	2.3e-23	0.69	0.53	0.35	FALSE
8	NTR	Blood	LIN7C	0.01	0.00	lasso	3	0.01	2.2e-03	10.66	-10.4	2.0e-25	-0.72	0.10	0.80	TRUE
9	ROSMAP	Brain Pre-frontal Cortex	METTL15	0.04	0.03	blup	364	0.03	4.6e-05	-3.18	-5.7	1.4e-08	-0.19	0.72	0.01	TRUE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LIN7C	0.04	0.01	lasso	3	0.02	1.0e-02	-1.78	6.1	9.3e-10	0.46	0.02	0.81	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	LIN7C	0.10	0.03	blup	32	0.08	2.8e-05	10.70	8.0	1.5e-15	0.57	0.01	0.96	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LIN7C	0.05	0.02	lasso	3	0.03	2.9e-04	10.68	9.5	1.9e-21	0.63	0.00	0.98	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIN7C	0.09	0.12	lasso	2	0.12	2.6e-13	3.32	5.7	1.2e-08	0.52	0.91	0.09	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	BDNFOS	0.03	0.01	blup	83	0.02	1.4e-03	1.69	5.3	1.3e-07	-0.13	0.34	0.02	TRUE
15	The Cancer Genome Atlas	Thyroid Carcinoma	LIN7C	0.09	0.10	enet	7	0.09	8.1e-09	3.32	5.2	2.3e-07	0.48	0.91	0.08	FALSE