[Hub]/) : Traits : Arm fat-free mass (right) :

chr1:752,566-3,191,909

Best TWAS P=8.73e-12 · Best GWAS P=1.11e-09 conditioned to 1.67e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RER1 0.06 0.00 blup 359 0.01 8.1e-03 0.92 -5.1 2.8e-07 0.30 0.04 0.14 FALSE
2 GTEx Adipose Subcutaneous C1orf86 0.15 0.05 enet 10 0.04 2.0e-04 -4.49 -5.9 4.5e-09 0.37 0.38 0.14 FALSE
3 GTEx Adipose Visceral Omentum RP1-283E3.4 0.26 0.05 enet 25 0.16 1.5e-08 -2.84 -5.1 3.0e-07 0.21 0.14 0.12 TRUE
4 GTEx Brain Cerebellar Hemisphere NADK 0.18 0.11 lasso 7 0.09 3.1e-03 -5.43 -5.6 2.4e-08 0.85 0.03 0.66 FALSE
5 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 -6.07 6.6 3.5e-11 -0.91 0.02 0.71 TRUE
6 GTEx Esophagus Mucosa TMEM52 0.17 0.18 lasso 2 0.20 2.9e-13 -5.30 5.3 1.4e-07 -0.83 0.42 0.58 FALSE
7 GTEx Lung NADK 0.07 0.03 lasso 3 0.02 8.5e-03 5.16 -5.7 1.4e-08 0.94 0.03 0.91 FALSE
8 GTEx Muscle Skeletal NADK 0.06 0.00 enet 9 0.00 1.3e-01 -5.43 -5.8 7.4e-09 0.79 0.05 0.84 FALSE
9 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 -5.69 5.8 5.8e-09 -0.84 0.09 0.91 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic TMEM52 0.19 0.18 lasso 4 0.14 2.6e-08 5.16 5.5 4.1e-08 -0.92 0.03 0.97 FALSE
11 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 5.58 5.7 1.5e-08 -0.92 0.04 0.96 FALSE
12 GTEx Spleen TMEM52 0.47 0.21 lasso 5 0.22 2.3e-06 -3.70 -5.3 1.1e-07 0.58 0.26 0.33 FALSE
13 METSIM Adipose TNFRSF14 0.07 0.05 blup 373 0.05 1.9e-07 4.22 6.8 8.7e-12 -0.08 0.78 0.18 TRUE
14 ROSMAP Brain Pre-frontal Cortex C1orf222 0.11 0.14 enet 18 0.14 1.8e-17 -4.39 5.8 8.4e-09 -0.70 0.95 0.05 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM52 0.02 0.01 blup 37 0.02 6.6e-03 -5.27 5.7 1.4e-08 -0.91 0.01 0.78 FALSE