Best TWAS P=5.15e-08 · Best GWAS P=3.11e-08 conditioned to 0.125
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Esophageal Carcinoma | ASCC3 | 0.11 | 0.07 | blup | 131 | 0.07 | 0.0024 | -4.2 | -5.2 | 2.1e-07 | -0.84 | 0.07 | 0.72 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | ASCC3 | 0.06 | 0.05 | lasso | 1 | 0.04 | 0.0002 | 5.4 | -5.5 | 5.1e-08 | -0.88 | 0.03 | 0.96 | TRUE |