TWAS hub - ASCC3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1460	0.0350	1.6e-10	0.038	0.080	0.078	0.064	0.064	1.7e-05	5.7e-10	8.7e-10	2.9e-08	3.3e-08
2	GTEx	Artery Aorta	0.0610	0.0320	9.2e-03	0.026	NA	0.007	NA	0.016	1.3e-02	NA	1.2e-01	NA	4.3e-02
3	GTEx	Artery Tibial	0.0997	0.0456	5.0e-04	0.078	NA	0.053	NA	0.055	1.1e-06	NA	5.6e-05	NA	3.8e-05
4	GTEx	Cells Transformed fibroblasts	0.2770	0.0650	9.3e-15	0.145	NA	0.227	NA	0.228	5.5e-11	NA	5.7e-17	NA	4.3e-17
5	GTEx	Esophagus Mucosa	0.2660	0.0640	9.2e-09	0.103	NA	0.114	NA	0.063	2.3e-07	NA	5.1e-08	NA	5.0e-05
6	GTEx	Muscle Skeletal	0.0896	0.0320	1.1e-04	0.031	NA	0.040	NA	0.033	4.6e-04	NA	7.2e-05	NA	3.3e-04
7	GTEx	Nerve Tibial	0.1311	0.0470	7.1e-04	0.054	NA	0.057	NA	0.051	1.1e-04	NA	7.3e-05	NA	1.7e-04
8	GTEx	Pancreas	0.1990	0.0680	1.6e-03	0.077	NA	0.069	NA	0.043	3.8e-04	NA	7.4e-04	NA	6.4e-03
9	GTEx	Prostate	0.3200	0.1190	5.5e-03	0.028	NA	0.010	NA	0.063	6.6e-02	NA	1.8e-01	NA	1.1e-02
10	GTEx	Skin Not Sun Exposed Suprapubic	0.2660	0.0740	3.6e-06	0.140	NA	0.179	NA	0.178	4.5e-08	NA	4.5e-10	NA	4.8e-10
11	GTEx	Skin Sun Exposed Lower leg	0.2410	0.0620	7.5e-08	0.131	NA	0.143	NA	0.144	6.1e-11	NA	6.6e-12	NA	5.6e-12
12	METSIM	Adipose	0.0416	0.0193	8.4e-03	0.019	0.008	0.008	0.010	0.015	7.1e-04	2.1e-02	2.2e-02	1.1e-02	2.5e-03
13	YFS	Blood	0.0232	0.0092	5.1e-04	0.019	0.009	0.015	0.014	0.019	4.2e-07	3.5e-04	9.0e-06	1.2e-05	5.3e-07
14	TCGA	Breast Invasive Carcinoma	0.0759	0.0268	5.8e-08	0.016	0.041	0.039	NA	0.040	2.1e-04	6.6e-09	1.6e-08	NA	1.1e-08
15	TCGA	Esophageal Carcinoma	0.1090	0.0610	1.0e-03	0.073	0.074	0.035	NA	-0.004	2.5e-03	2.4e-03	2.8e-02	NA	4.4e-01
16	TCGA	Head and Neck Squamous Cell Carcinoma	0.0820	0.0352	2.2e-06	0.054	0.056	0.038	NA	0.046	1.1e-06	5.8e-07	3.7e-05	NA	6.1e-06
17	TCGA	Kidney Renal Clear Cell Carcinoma	0.1726	0.0814	1.8e-04	0.018	0.023	0.032	NA	0.038	3.7e-03	1.1e-03	1.5e-04	NA	3.7e-05
18	TCGA	Lung Squamous Cell Carcinoma	0.1432	0.0580	7.7e-05	0.046	0.046	0.062	NA	0.050	5.0e-06	4.9e-06	1.4e-07	NA	2.5e-06
19	TCGA	Thyroid Carcinoma	0.0560	0.0450	4.9e-04	0.052	0.018	0.021	NA	0.036	8.8e-06	6.7e-03	3.2e-03	NA	2.0e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Seen doctor (GP) for nerves, anxiety, tension or depression	6.6	10.1	21.2	-0.2	2.8	2.8	-3.5	-4.6	-4.3	-3.9	-3.7	1.5	-2.6	-3.1	-1.2	-2.8	-2.9	-4.1	-3.3	-2.9	-3.4	-3.4
Age when periods started (menarche)	6.2	14.8	46.9	-1.4	-5.6	-5.7	5.1	4.2	2.3	1.8	1.6	-3.8	2.4	2.2	-0.9	1.3	2.9	6.5	4.3	3.7	1.8	6.8
Neuroticism score	6.0	12.6	26.9	1.6	3.5	3.4	-4.6	-4.7	-3.0	-2.4	-3.3	2.2	-2.7	-2.8	-0.2	-2.8	-2.9	-5.2	-4.3	-4.5	-4.2	-4.9
Depressed Affect (Nagel 2018)	5.9	12.5	24.5	2.1	4.2	4.0	-4.7	-4.6	-3.2	-3.0	-4.0	2.8	-2.8	-2.4	-0.2	-2.5	-2.6	-5.0	-3.9	-4.1	-3.4	-4.3
Neuroticism (Nagel 2018)	5.9	13.9	31.5	1.6	4.4	4.2	-4.9	-4.8	-3.4	-2.6	-4.0	3.2	-2.9	-2.4	-0.2	-2.5	-2.6	-5.6	-4.3	-4.6	-3.1	-5.0
Neuroticism	5.8	14.1	30.2	1.7	4.2	4.1	-5.0	-4.7	-3.1	-2.6	-3.8	2.9	-2.8	-2.5	0.3	-2.4	-2.7	-5.5	-4.2	-5.0	-3.9	-5.2
Miserableness	5.3	9.2	19.6	1.1	4.1	3.7	-4.0	-3.6	-2.8	-2.7	-3.5	2.8	-2.0	-1.9	0.6	-2.2	-2.3	-4.4	-3.4	-2.9	-2.2	-4.0
Tense / ‘highly strung’	4.9	8.1	20.2	0.6	2.3	2.7	-3.8	-3.8	-2.5	-2.2	-2.2	1.8	-2.4	-2.4	-0.5	-1.8	-1.9	-4.5	-3.1	-3.8	-3.1	-4.4
Loneliness, isolation	4.8	6.6	17.2	1.7	2.3	2.1	-3.6	-3.6	-1.4	-1.5	-1.8	2.6	-1.6	-1.3	0.7	-1.4	-1.3	-3.9	-2.6	-3.9	-3.1	-4.1
Guilty feelings	4.7	7.1	15.8	1.4	3.4	3.1	-3.3	-3.3	-2.6	-1.9	-2.6	1.9	-2.3	-2.3	-0.6	-2.0	-2.3	-4.0	-3.3	-2.4	-1.9	-3.5
Mood swings	4.6	8.3	19.0	1.6	3.7	3.2	-3.8	-3.7	-2.6	-2.7	-3.0	2.0	-2.1	-1.8	-0.2	-2.1	-2.0	-4.4	-2.9	-2.9	-2.6	-4.2
Medication: Simvastatin	4.5	6.6	19.7	-0.4	-1.9	-1.5	3.5	3.5	2.0	2.2	1.2	-1.1	2.1	2.2	0.8	2.0	2.9	3.0	3.2	3.9	4.4	2.5
Ever depressed for a whole week	4.2	5.2	9.9	-1.2	2.1	2.0	-2.2	-2.8	-2.7	-3.2	-2.9	1.5	-2.2	-2.4	-1.2	-2.2	-2.5	-2.7	-2.8	-1.3	-1.6	-2.2
Smoking Status	4.1	9.7	25.9	3.0	4.8	5.1	-4.9	-3.6	-0.8	-0.1	-0.3	1.7	0.3	-0.2	2.7	0.6	-1.2	-4.6	-1.9	-4.5	-2.4	-5.1
Major Depression (MDD)	4.0	4.9	10.3	0.4	3.2	3.1	-2.5	-2.9	-1.9	-2.5	-2.8	1.6	-1.2	-1.6	0.0	-1.6	-1.5	-3.1	-2.6	-1.7	-1.8	-2.6
Relative age voice broke	3.8	5.8	19.1	-1.5	-4.2	-4.4	3.5	2.9	1.6	0.2	0.8	-1.4	1.0	0.7	0.0	0.5	1.8	4.0	2.7	2.6	0.7	3.3
Irritability	3.8	6.5	22.3	1.6	2.2	2.3	-4.0	-3.1	-2.1	-0.6	-0.4	3.1	-0.5	-0.2	1.2	0.1	-0.6	-3.7	-2.0	-4.7	-3.6	-3.9
Other serious medical condition/disability diagnosed by doctor	3.7	4.9	11.0	0.4	1.9	1.6	-2.9	-3.3	-2.1	-2.1	-2.0	1.0	-2.1	-2.1	-1.2	-1.7	-2.3	-3.2	-2.8	-1.9	-2.7	-2.5
Supplements: Zinc	3.5	3.8	8.0	-0.9	1.2	1.7	-1.8	-2.8	-2.2	-2.7	-1.6	-0.0	-2.1	-2.5	-1.9	-1.9	-2.4	-2.0	-2.0	-1.6	-2.0	-1.7
High cholesterol (Self-reported)	3.4	6.0	17.1	0.2	-1.8	-1.8	3.3	3.0	2.6	2.4	1.4	-0.8	2.0	2.3	1.8	2.3	2.9	2.7	3.0	3.1	4.1	1.9
Mouth/teeth dental problems: Loose teeth	3.3	3.9	13.4	2.8	3.1	3.7	-3.1	-1.9	-0.6	0.8	0.1	0.9	-0.2	0.1	1.6	0.4	-0.9	-2.7	-1.1	-2.4	-1.2	-3.0
Suffer from ‘nerves’	3.3	5.2	9.2	0.2	1.4	1.5	-2.6	-3.0	-2.9	-1.9	-2.4	2.2	-1.9	-2.1	-0.3	-2.0	-2.1	-2.9	-2.9	-2.4	-2.9	-2.9
Financial situation satisfaction	3.3	4.1	8.8	-2.7	0.9	0.8	-1.8	-2.7	-2.4	-3.0	-1.7	1.1	-2.4	-2.7	-1.0	-2.1	-2.8	-1.9	-2.0	-0.9	-1.9	-1.4
Sensitivity / hurt feelings	3.0	5.2	14.8	0.6	3.2	3.1	-3.1	-2.5	-2.3	-0.4	-0.4	1.4	-1.3	-1.3	0.3	-1.2	-1.7	-3.9	-2.8	-2.9	-1.6	-3.7
Birth weight	3.0	6.6	17.2	-0.7	-2.4	-2.2	3.5	4.1	1.7	2.0	3.1	0.2	3.0	2.2	1.0	1.8	2.7	2.7	3.0	3.1	3.7	1.9
Impedance of arm (left)	2.9	13.3	36.5	-1.2	-5.0	-5.1	4.6	4.0	2.8	1.4	1.6	-5.8	2.0	1.6	-1.1	0.7	2.2	5.8	3.7	3.9	2.0	6.0
Worry (Nagel 2018)	2.8	5.8	14.6	0.4	1.6	1.8	-2.6	-3.3	-2.1	-2.2	-3.8	1.9	-2.4	-2.2	-0.6	-2.1	-1.9	-3.1	-2.8	-3.0	-2.6	-2.6
Past tobacco smoking	2.8	5.1	13.0	-0.9	-3.3	-3.6	3.1	3.2	1.4	1.7	1.5	-1.3	0.9	1.5	-0.3	1.1	1.7	3.3	2.3	2.4	1.9	3.2
Hearing difficulty/problems with background noise	2.8	4.5	11.8	2.3	2.6	2.4	-2.9	-2.4	-1.5	-0.6	-1.0	3.4	-1.0	-0.7	-0.6	-1.1	-0.4	-3.4	-2.1	-3.0	-1.9	-2.6
LDL Cholesterol	2.7	4.3	9.0	-0.9	-2.9	-2.8	2.5	2.2	1.4	1.3	1.1	-1.1	1.9	2.2	0.3	2.1	2.2	3.0	2.7	1.5	1.9	2.6
Average weekly fortified wine intake	2.7	3.2	7.3	-0.7	-2.1	-2.2	2.3	2.6	1.8	1.4	2.7	-0.2	1.9	1.8	0.9	1.7	2.3	1.6	1.6	0.8	1.9	1.4
Nervous feelings	2.7	5.1	12.9	0.8	1.0	0.9	-2.1	-3.1	-2.4	-2.4	-3.6	0.7	-2.2	-2.3	-0.5	-2.5	-1.1	-3.1	-2.3	-2.5	-2.8	-3.0
Medication: Cholesterol lowering	2.7	4.1	13.7	-0.1	-0.5	-0.6	2.2	2.4	1.8	1.6	1.4	-1.0	2.1	2.1	2.0	2.4	2.3	2.0	2.9	2.5	3.7	1.3
Commuting to job workplace: Car/motor vehicle	2.7	3.1	9.1	0.0	-1.7	-1.6	2.0	1.9	1.8	0.1	1.6	-1.1	2.0	1.6	1.5	1.4	2.3	2.4	3.0	1.9	1.5	1.8
Ever smoked	2.7	4.7	11.5	0.9	3.1	3.4	-3.1	-3.2	-1.5	-1.6	-1.3	1.4	-0.6	-1.2	0.6	-0.7	-1.4	-3.3	-2.0	-2.5	-1.9	-3.0
Fasting Glucose	2.5	2.9	8.0	-0.8	0.3	0.1	-1.0	-1.5	-2.0	-2.0	-1.4	2.8	-2.2	-2.2	-1.1	-2.0	-1.7	-1.9	-2.3	-1.6	-1.3	-1.9
Impedance of arm (right)	2.5	11.8	35.5	-1.4	-4.7	-4.6	4.4	3.3	2.4	1.1	1.2	-6.0	1.8	1.2	-1.4	0.3	1.7	5.5	3.4	3.6	1.7	6.0
Comparative body size at age 10	2.5	6.8	24.0	4.8	4.2	3.9	-3.1	-1.7	1.0	0.4	-0.2	0.5	0.7	1.4	3.0	1.3	1.4	-3.8	-0.4	-2.6	-0.0	-4.9
Smoking status: Previous	2.5	3.7	8.6	0.4	2.7	2.9	-2.7	-2.6	-1.0	-1.6	-1.6	1.2	-1.0	-1.7	0.1	-1.3	-1.9	-2.6	-2.1	-1.8	-2.0	-2.4
Handedness (chirality/laterality): Left-handed	2.5	3.0	6.8	-0.1	2.2	2.2	-2.2	-1.9	-1.8	-1.1	-1.4	2.6	-0.8	-1.3	0.1	-1.4	-1.2	-2.4	-1.6	-0.8	-1.9	-2.5
Average weekly beer plus cider intake	2.5	3.6	15.0	3.9	2.0	2.1	-2.6	-2.0	0.3	1.3	0.0	1.9	0.2	1.0	1.7	1.3	0.8	-2.2	-0.1	-2.6	-1.4	-3.0
Heart attack/myocardial infarction (self-reported)	2.5	3.2	5.8	-0.6	-1.2	-1.4	1.7	2.1	1.9	1.4	1.4	-2.3	1.9	2.0	1.3	1.6	1.7	2.4	2.2	1.6	2.0	2.2
Severe depression (siblings)	2.4	2.6	6.1	0.5	2.5	2.1	-2.4	-2.1	-2.0	-1.5	-1.5	0.2	-1.2	-1.2	-0.2	-1.5	-1.1	-1.9	-1.3	-1.5	-2.1	-1.6
Diverticular disease/diverticulitis (self-reported)	2.4	2.8	6.5	0.8	2.4	2.5	-2.1	-1.9	-1.2	-1.2	-1.1	-0.0	-0.8	-1.2	0.1	-1.9	-2.1	-2.1	-2.1	-1.1	-1.9	-2.2
Impedance of whole body	2.4	12.3	39.6	-1.0	-4.7	-4.8	4.0	3.4	2.7	1.5	1.2	-5.9	2.1	2.1	-1.0	1.0	2.2	5.8	3.7	2.9	1.7	6.3
Arm predicted mass (left)	2.4	12.3	31.8	0.0	4.5	4.3	-4.3	-3.4	-3.5	-2.6	-1.3	4.5	-2.0	-2.6	0.6	-2.3	-3.0	-5.6	-4.5	-2.9	-2.7	-5.6
Mean Putamen Volume	2.3	2.6	8.9	1.9	1.9	1.9	-2.1	-1.4	-0.3	-0.5	-1.0	2.2	-0.4	-0.7	1.0	-1.4	0.0	-2.5	-1.0	-1.4	-2.1	-3.0
Arm fat-free mass (left)	2.3	11.8	32.3	0.1	4.4	4.3	-4.2	-3.4	-3.4	-2.4	-1.2	4.3	-1.9	-2.5	0.8	-2.1	-2.8	-5.6	-4.3	-2.9	-2.6	-5.7
Heart attack	2.2	2.8	4.9	-0.4	-1.1	-1.3	1.6	2.0	1.7	1.3	1.3	-2.0	1.8	2.0	1.3	1.6	1.7	2.2	2.0	1.5	2.0	2.0
Birth weight of first child	2.2	3.9	9.7	-0.4	-1.8	-1.5	1.7	2.3	2.0	1.3	2.6	-1.6	3.1	2.7	2.2	2.0	2.2	2.2	2.6	0.6	0.9	1.3
Glaucoma (self-reported)	2.2	2.6	8.0	-1.2	-2.6	-2.8	2.7	2.4	0.3	0.1	0.8	0.2	-0.3	0.1	-0.6	0.0	1.1	1.9	0.9	2.2	2.2	2.0
Wheeze or whistling in the chest in last year	2.2	3.9	9.0	-0.0	2.7	2.7	-2.6	-2.3	-1.7	-1.4	-1.3	1.7	-1.5	-1.5	-1.0	-1.4	-2.1	-2.9	-3.0	-1.6	-1.5	-2.1
Ever unenthusiastic/disinterested for a whole week	2.1	2.6	7.3	-1.3	1.5	1.4	-2.1	-1.5	-2.0	-2.7	-1.5	0.6	-1.2	-1.4	-0.1	-1.6	-1.5	-2.0	-1.8	-1.3	-1.7	-1.5
Happiness	2.1	2.5	4.4	-1.5	0.9	1.2	-1.8	-2.1	-2.1	-1.7	-1.1	1.8	-1.8	-1.7	-0.7	-1.3	-1.9	-1.9	-1.8	-1.5	-1.4	-1.2
Stomach or abdominal pain in last month	2.0	2.5	7.3	0.5	0.3	0.3	-1.9	-2.1	-1.2	-1.3	-1.4	-0.3	-1.4	-1.5	-0.9	-2.1	-1.0	-2.0	-2.3	-2.3	-2.7	-1.5
Worrier / anxious feelings	2.0	3.7	9.0	0.8	2.1	2.3	-2.7	-2.7	-0.9	-0.8	-2.0	1.5	-0.9	-0.7	1.1	-0.6	-1.1	-2.9	-2.0	-2.8	-1.9	-3.0
Arm fat-free mass (right)	2.0	10.3	29.7	0.3	4.2	4.0	-3.9	-2.7	-3.0	-2.2	-1.0	4.7	-1.6	-2.1	1.0	-2.0	-2.3	-5.2	-3.8	-2.7	-2.4	-5.5
Family relationship satisfaction	2.0	2.5	5.7	0.2	1.7	1.7	-1.8	-1.8	-1.4	-1.4	-1.6	2.3	-1.4	-1.2	0.0	-1.2	-1.1	-2.2	-1.3	-1.0	-1.6	-2.4
Ever taken oral contraceptive pill	2.0	2.2	5.1	-1.0	1.8	1.6	-1.6	-1.6	-2.3	-1.3	-1.6	0.7	-2.1	-1.4	-1.5	-0.9	-1.9	-1.6	-1.8	-0.6	-0.3	-0.7
Bipolar Disorder (2011)	1.9	1.8	6.5	1.7	1.6	1.9	-2.2	-1.5	-0.1	-0.2	0.0	1.0	0.3	0.5	1.3	0.5	0.5	-1.9	-0.2	-1.8	-1.3	-2.5
BMI	1.9	10.9	37.1	1.9	5.4	5.1	-4.5	-2.2	-2.0	-0.8	1.3	4.3	-0.1	-0.5	2.7	0.2	-1.3	-5.6	-3.2	-3.2	-0.6	-6.1
Frequency of tenseness / restlessness in last 2 weeks	1.9	2.9	8.2	0.6	1.9	1.7	-2.6	-2.4	-1.2	-1.2	-0.8	1.4	-0.8	-0.7	0.9	-0.4	-0.9	-2.8	-1.6	-2.2	-1.7	-2.9
Hypothyroidism/myxoedema (self-reported)	1.9	3.6	6.7	-0.2	1.4	1.3	-1.6	-2.0	-2.2	-2.2	-2.3	1.2	-2.6	-2.1	-1.5	-2.1	-1.9	-2.4	-2.2	-1.0	-1.9	-2.2
Neck or shoulder pain in last month	1.9	2.7	9.0	3.0	2.4	2.3	-1.9	-0.8	0.8	1.0	0.8	-0.2	1.4	1.0	2.4	0.9	0.9	-2.1	-0.2	-1.6	-0.4	-2.6
Arm predicted mass (right)	1.9	9.7	27.7	0.1	4.1	4.0	-3.8	-2.6	-2.9	-2.1	-0.9	4.7	-1.6	-2.0	0.9	-1.9	-2.3	-5.1	-3.8	-2.6	-2.2	-5.3
Depression (Nagel 2018)	1.8	2.7	8.1	0.8	2.0	2.0	-2.2	-2.9	-1.5	-1.2	-2.3	0.1	-1.1	-1.1	0.1	-0.9	-1.0	-2.1	-1.4	-2.0	-1.8	-1.6
Type 2 Diabetes (T2D) (2012)	1.8	2.0	4.2	-0.8	0.7	0.6	-0.9	-1.6	-1.4	-1.4	-1.4	0.9	-2.0	-2.0	-1.1	-1.9	-2.0	-1.6	-1.9	-1.2	-1.5	-0.6
Trunk predicted mass	1.8	10.0	30.0	0.4	4.3	4.2	-3.9	-2.8	-2.6	-1.8	-0.6	4.5	-1.4	-2.1	1.1	-1.8	-2.4	-5.2	-3.8	-2.8	-2.3	-5.5
Asthma (self-reported)	1.8	3.6	10.1	0.8	1.5	1.5	-2.2	-2.2	-1.4	-0.9	-0.4	2.2	-1.1	-1.1	-0.9	-1.1	-1.2	-3.0	-2.6	-2.6	-2.3	-3.2
Number of self-reported non-cancer illnesses	1.8	3.1	8.4	0.1	1.9	1.7	-2.1	-2.2	-1.4	-1.4	-1.3	0.1	-1.4	-1.9	-1.1	-1.8	-1.6	-2.9	-2.6	-0.9	-1.5	-2.6
Age at First Birth	1.7	2.5	4.0	-0.2	-1.8	-1.5	1.9	1.8	1.7	1.1	1.4	-0.7	1.8	1.9	1.6	1.8	2.0	1.7	1.6	1.0	1.8	1.4
Relative age of first facial hair	1.7	3.4	8.8	-1.0	-2.4	-2.8	2.8	2.6	1.0	1.3	0.8	0.2	1.0	0.9	0.2	0.6	1.3	3.0	1.9	2.6	1.6	2.5
Current tobacco smoking	1.7	2.8	6.7	2.5	1.5	1.9	-2.1	-1.2	0.6	1.3	1.0	1.0	1.6	1.4	2.4	1.6	1.2	-1.9	0.7	-2.5	-0.7	-2.6
Supplements: Glucosamine	1.7	2.2	6.6	0.5	2.3	2.6	-2.0	-1.9	0.3	-0.6	0.7	1.1	0.2	-0.4	0.3	0.4	-1.0	-2.3	-1.5	-2.0	-0.7	-2.5
Number of incorrect matches in round	1.7	2.8	5.2	-0.1	1.0	1.1	-1.4	-2.0	-1.8	-2.3	-2.2	0.7	-1.8	-1.9	-2.2	-1.8	-1.9	-1.3	-2.0	-1.4	-1.9	-0.8
Trunk fat-free mass	1.7	9.6	28.5	0.3	4.1	4.0	-3.8	-2.7	-2.7	-1.9	-0.6	4.4	-1.4	-2.1	1.1	-1.8	-2.4	-5.1	-3.7	-2.6	-2.2	-5.3
Asthma	1.7	3.3	8.9	0.5	1.4	1.2	-2.0	-2.2	-1.6	-0.9	-0.5	2.0	-1.3	-1.3	-1.1	-1.3	-1.3	-2.9	-2.7	-2.4	-2.2	-3.0
Long-standing illness, disability or infirmity	1.7	2.6	8.3	0.0	0.8	1.2	-1.8	-2.9	-1.7	-1.7	-0.9	0.8	-1.4	-1.9	-0.9	-1.1	-1.0	-2.6	-1.7	-1.0	-1.8	-2.4
Whole body water mass	1.7	9.4	29.2	0.0	4.1	3.9	-3.5	-2.5	-2.8	-2.1	-0.7	4.5	-1.5	-2.3	1.0	-2.0	-2.5	-5.1	-3.8	-2.2	-2.1	-5.4
Medication: Atorvastatin	1.7	2.0	6.0	-1.5	-2.0	-2.4	2.4	1.2	0.7	-0.8	-0.4	-1.4	0.3	0.1	0.2	0.0	1.3	1.8	1.7	2.3	1.2	1.5
Lupus	1.6	2.5	6.5	-1.4	-0.1	-0.2	-0.3	-1.3	-1.9	-1.9	-1.8	0.1	-2.3	-2.5	-1.9	-2.2	-1.7	-1.1	-1.6	-0.0	-2.1	-0.6
Fed-up feelings	1.6	2.8	7.9	2.0	1.8	1.6	-2.3	-2.3	-0.6	-1.2	-1.5	1.3	-0.6	-0.4	0.8	-0.7	-0.4	-2.6	-1.6	-2.8	-1.7	-2.5
Hayfever, allergic rhinitis or eczema	1.6	3.4	8.4	-2.1	0.2	-0.3	0.2	-1.1	-2.1	-2.6	-2.3	0.6	-2.4	-2.9	-2.8	-2.7	-2.0	-1.1	-2.2	0.7	-1.1	-0.7
Worry too long after embarrassment	1.6	2.6	10.3	1.4	2.1	1.3	-1.7	-1.0	-0.7	-0.5	-1.0	2.3	-0.3	-0.6	0.8	-1.2	-0.3	-3.1	-2.2	-1.5	-0.8	-3.2
Leg fat mass (right)	1.6	6.4	19.4	0.8	3.9	3.5	-3.4	-2.6	-1.6	-1.6	-0.6	2.6	-0.7	-1.6	1.2	-1.2	-1.6	-4.3	-2.9	-2.1	-1.7	-4.4
Whole body fat-free mass	1.6	8.9	27.9	-0.0	3.9	3.7	-3.4	-2.4	-2.7	-2.1	-0.7	4.3	-1.4	-2.2	1.0	-2.0	-2.4	-5.0	-3.7	-2.1	-2.0	-5.3
Commuting to job workplace: Public transport	1.6	2.0	5.3	0.0	0.8	0.6	-1.7	-1.2	-1.8	-0.4	-0.9	0.7	-1.6	-1.1	-1.4	-1.2	-1.3	-2.0	-2.3	-2.2	-1.6	-1.2
Eye problems/disorders: Glaucoma	1.6	1.9	4.4	0.3	-2.1	-2.1	1.8	1.9	1.1	0.4	1.3	-0.5	0.9	1.1	0.9	1.0	1.9	1.6	1.3	1.3	1.5	1.4
Illnesses of father: High blood pressure	1.6	2.0	6.1	-2.5	-1.4	-1.6	2.2	2.0	-0.4	-0.4	-0.4	-0.6	-0.6	-0.4	-1.2	-0.3	0.2	1.5	0.5	2.4	1.9	1.7
Basal metabolic rate	1.6	9.0	28.1	-0.1	4.0	3.7	-3.4	-2.4	-2.8	-2.3	-0.7	4.1	-1.4	-2.4	1.0	-2.1	-2.5	-5.0	-3.8	-1.9	-2.0	-5.3
Cholesterol lowering medication	1.6	2.4	8.5	-0.5	-2.2	-1.9	2.7	1.8	0.8	0.7	-0.5	-0.6	0.5	0.7	-0.2	0.4	1.7	1.9	1.5	2.9	2.2	1.7
Bipolar Disorder (2018)	1.5	2.4	5.2	1.9	2.0	2.3	-1.6	-0.7	1.2	1.2	1.6	1.0	1.7	2.0	1.9	2.2	1.3	-1.2	0.9	-1.5	0.4	-1.4
Number of live births	1.5	2.2	6.1	-0.8	-1.7	-2.0	1.9	1.9	0.8	0.8	0.8	-1.3	0.8	1.1	-0.2	0.4	1.4	2.2	1.6	1.9	1.4	2.5
Pulse wave peak to peak time	1.5	1.8	5.5	1.0	2.3	2.3	-2.0	-1.7	-1.2	-0.3	-1.0	0.1	-0.8	-0.7	0.0	-0.2	-1.2	-1.8	-1.2	-1.5	-0.9	-1.6
Osteoarthritis (self-reported)	1.5	1.9	3.3	-1.6	0.4	0.4	-1.2	-1.4	-1.1	-1.2	-1.0	1.5	-1.6	-1.7	-1.1	-1.7	-1.8	-1.5	-1.8	-0.7	-1.8	-1.4
Supplements: Calcium	1.5	1.6	3.0	-0.5	1.4	1.5	-0.7	-1.7	-1.1	-0.7	-1.6	-1.7	-1.0	-1.7	-1.4	-1.3	-1.7	-1.3	-1.6	0.2	-0.3	-1.2
Ever had hysterectomy (womb removed)	1.4	1.6	6.2	0.4	1.1	1.7	-1.6	-1.4	-0.2	0.8	0.5	1.1	-0.1	-0.3	0.6	-0.0	-1.4	-1.7	-1.8	-2.5	-1.3	-1.8
Weight	1.4	6.8	19.6	-0.1	3.5	3.2	-2.9	-2.2	-2.6	-2.4	-0.8	2.8	-1.4	-2.4	0.7	-2.1	-2.4	-4.3	-3.5	-1.4	-1.8	-4.4
Length of working week for main job	1.4	1.5	5.0	0.8	1.5	1.5	-1.0	0.8	1.0	0.5	1.6	1.2	1.6	1.6	2.2	1.6	0.6	-0.8	0.3	-1.1	0.7	-1.0
Number of children fathered	1.4	1.5	4.0	-2.0	0.2	-0.3	0.6	0.1	-1.3	-1.7	-1.1	-0.3	-1.7	-1.7	-1.8	-1.8	-1.8	0.2	-1.2	1.1	0.2	0.8
Medication: Gliclazide	1.4	1.6	6.4	1.9	1.6	1.7	-1.1	-0.5	1.1	1.0	1.5	2.5	1.0	0.7	1.5	0.9	0.7	-1.1	0.2	-0.9	0.8	-1.2
Rheumatoid Arthritis	1.3	1.8	4.8	-1.1	-1.6	-1.5	2.1	1.7	1.3	0.2	-0.0	-2.1	0.1	0.2	-0.3	0.0	0.6	2.0	0.7	1.8	1.1	2.2
Leg fat-free mass (left)	1.3	6.7	23.0	-0.4	3.4	3.0	-2.5	-1.6	-2.4	-2.2	-0.7	3.7	-1.2	-2.3	0.7	-2.1	-2.1	-4.4	-3.4	-1.1	-1.5	-4.8
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	5.2	-0.1	0.8	1.1	-1.8	-1.7	-0.7	-0.4	0.2	-0.2	-0.7	-1.0	0.4	-0.5	-1.6	-1.5	-1.5	-2.0	-2.3	-1.5
Body mass index (BMI)	1.3	5.7	19.7	0.8	3.5	3.1	-2.9	-2.2	-1.9	-1.4	-0.7	3.2	-1.0	-1.6	1.0	-1.1	-1.5	-4.1	-2.7	-1.7	-1.2	-4.4
Leg predicted mass (left)	1.3	6.7	22.8	-0.4	3.4	3.0	-2.5	-1.7	-2.4	-2.2	-0.8	3.6	-1.2	-2.3	0.8	-2.1	-2.1	-4.4	-3.4	-1.1	-1.6	-4.8
Alcohol intake versus 10 years previously	1.3	2.0	7.3	0.3	1.8	1.8	-2.1	-1.0	-0.1	0.6	0.7	2.7	0.2	0.3	1.4	0.4	-0.4	-2.1	-0.9	-1.6	-0.2	-2.6
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.0	8.2	1.8	1.9	1.2	-1.9	-1.3	0.1	-0.5	-1.2	1.4	0.2	-0.4	1.5	-0.7	0.3	-2.6	-1.1	-1.0	-0.9	-2.9
Medication: Ventolin 100micrograms inhaler	1.3	1.7	5.3	-0.0	1.4	1.2	-1.8	-1.5	-0.8	0.1	0.3	0.7	-0.7	-0.8	-0.3	-0.4	-1.5	-2.3	-2.1	-1.8	-1.2	-2.1
Medication: Seretide 50 evohaler	1.3	1.5	3.8	1.2	1.7	1.4	-1.7	-1.3	-0.4	-0.1	-0.5	1.5	-0.3	0.1	-0.1	-0.1	-0.6	-2.0	-1.8	-1.9	-0.5	-1.8
Commuting to job workplace: Walk	1.3	1.4	2.7	1.5	1.5	1.2	-1.5	-1.5	-0.4	0.1	-1.0	1.5	-0.9	-0.7	0.3	-0.2	-0.8	-1.5	-1.1	-1.6	-1.4	-1.6
Smoking status: Current	1.3	2.0	5.2	2.0	1.5	1.8	-1.9	-1.1	0.2	1.0	0.9	0.9	1.1	1.0	1.7	1.3	0.8	-1.8	0.3	-2.3	-0.4	-2.3
Pain experienced in last month	1.3	2.2	4.3	-0.1	-0.9	-0.9	1.4	2.1	0.9	1.2	2.0	1.3	1.6	1.7	0.8	1.7	1.4	1.9	1.9	0.9	1.9	1.9
Leg fat mass (left)	1.3	5.2	15.4	0.6	3.6	3.3	-3.0	-2.3	-1.5	-1.6	-0.6	2.3	-0.6	-1.5	1.1	-1.1	-1.5	-3.9	-2.7	-1.8	-1.3	-3.9
HDL Cholesterol	1.2	2.0	5.9	-0.4	-1.3	-1.5	0.1	-0.8	-1.7	-1.4	-1.2	-2.0	-1.4	-1.7	-2.4	-1.9	-1.0	1.0	-0.0	0.1	-2.4	1.3
Allergy or Eczema	1.2	3.2	8.4	-1.6	-0.0	-0.4	0.3	-1.0	-2.1	-2.5	-2.2	0.2	-2.5	-2.9	-2.8	-2.6	-2.0	-0.9	-2.1	0.5	-1.2	-0.4
Frequency of depressed mood in last 2 weeks	1.2	1.7	4.6	0.8	1.6	1.6	-2.1	-2.1	-0.6	-0.6	-0.9	0.3	-0.1	-0.3	0.9	-0.2	-0.5	-1.9	-0.8	-2.0	-1.3	-2.1
Taking other prescription medications	1.2	1.9	5.3	0.3	1.9	1.9	-1.2	-1.6	-1.1	-1.1	-1.1	0.2	-1.3	-1.3	-1.7	-1.2	-1.1	-2.3	-1.7	0.4	0.4	-1.9
Impedance of leg (left)	1.2	5.8	21.9	-0.3	-3.1	-3.1	2.2	1.8	1.9	1.1	0.7	-4.5	1.3	1.8	-0.5	1.0	1.6	4.1	2.7	1.1	1.0	4.7
Hip circumference	1.2	5.4	14.4	-0.6	3.0	2.6	-2.4	-1.9	-1.9	-1.9	0.3	2.4	-0.9	-2.6	-0.1	-2.2	-2.5	-3.8	-3.6	-1.2	-1.4	-3.6
Pulse wave Arterial Stiffness index	1.2	1.3	4.6	-1.4	-2.1	-2.2	1.7	1.4	0.9	-0.2	0.6	0.0	0.5	0.2	-0.3	-0.2	0.8	1.5	0.8	1.4	0.5	1.5
Ever highly irritable/argumentative for 2 days	1.2	1.5	4.3	-1.5	0.3	-0.0	-0.4	-0.6	-1.9	-2.1	-0.5	-0.3	-1.7	-1.6	-1.3	-1.5	-1.5	-1.3	-1.7	-0.5	-0.4	-0.9
Leg fat percentage (right)	1.2	4.5	12.3	0.9	3.3	3.0	-3.0	-2.6	-1.4	-1.2	-0.9	1.6	-0.8	-1.4	0.8	-1.0	-1.4	-3.5	-2.3	-1.9	-1.5	-3.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	3.5	0.2	0.7	0.5	-1.3	-1.7	-1.4	-1.5	-1.2	0.6	-1.2	-1.2	-0.1	-1.1	-1.0	-1.9	-1.8	-1.2	-1.4	-1.6
Shortness of breath walking on level ground	1.2	1.4	8.5	-0.3	0.8	0.8	-1.0	-0.8	-0.5	-0.6	-0.7	2.9	-1.0	-1.3	-0.1	-1.1	-1.1	-1.6	-1.4	-0.5	-1.1	-1.9
Respiratory disease	1.1	2.5	8.1	0.8	2.0	2.2	-1.9	-1.2	-0.6	0.2	0.4	2.2	-0.4	-0.4	0.0	-0.5	-1.1	-2.6	-2.5	-1.9	-0.9	-2.8
Average weekly spirits intake	1.1	1.4	4.6	-0.1	-1.4	-1.3	1.5	1.2	2.0	1.8	0.9	-2.1	0.9	0.2	0.8	0.5	0.4	1.3	0.7	1.3	0.2	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	4.1	1.9	1.4	1.2	-1.7	-1.4	-0.4	0.1	-0.9	0.7	0.4	0.3	1.8	0.2	0.4	-1.5	-0.0	-1.4	-1.5	-2.0
High blood pressure (mother)	1.1	1.6	5.7	1.4	0.6	0.5	-0.8	0.5	1.0	1.5	1.4	0.9	1.9	1.9	2.4	1.7	1.3	-0.2	0.7	-1.6	-0.1	-0.5
Waist circumference	1.1	3.9	9.6	-0.0	2.1	1.8	-2.4	-2.0	-2.1	-2.1	-1.1	2.3	-1.5	-1.7	0.8	-1.6	-1.5	-3.0	-2.3	-1.7	-2.1	-3.1
Financial difficulties in last 2 years	1.1	1.5	4.4	-1.0	1.1	1.1	-1.6	-2.1	-1.4	-0.8	-0.8	-0.0	-0.7	-0.8	0.5	-0.7	-0.9	-1.6	-1.0	-1.8	-1.6	-1.6
Allergy	1.1	2.6	5.8	1.9	0.3	0.7	-0.1	1.1	1.7	2.2	1.8	-1.3	2.0	2.4	2.1	2.3	1.6	1.3	2.3	-0.1	1.4	1.2
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	7.4	0.8	1.0	0.9	-1.6	-0.8	0.2	-0.7	0.4	0.3	0.3	0.3	1.6	0.5	-0.4	-1.4	-1.2	-2.7	-1.5	-2.0
Blood clot in the leg (DVT)	1.1	1.4	4.5	-1.4	-2.0	-2.1	2.1	1.4	1.2	-0.1	-0.3	0.2	0.5	0.0	0.5	-0.2	0.6	1.6	0.7	1.7	1.1	1.2
Number of full brothers	1.1	1.4	5.9	0.7	0.9	0.3	-2.0	-1.3	-0.8	-0.8	-0.3	1.3	-0.2	-0.4	1.3	-0.7	-0.1	-1.5	-0.9	-2.4	-2.0	-1.3
Health satisfaction	1.1	1.5	6.4	-2.5	-1.4	-1.3	-0.4	-0.5	-1.5	-1.7	0.1	1.8	-1.4	-1.4	-0.7	-1.1	-1.1	-0.6	-1.1	-0.3	-1.0	-0.2
Medication: Blood pressure	1.1	2.0	7.4	0.5	-0.8	-0.6	1.5	1.6	1.2	1.5	1.8	-0.5	1.6	1.5	1.5	1.8	2.0	0.9	1.2	1.1	2.7	0.3
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	2.7	1.6	0.5	0.5	0.3	1.2	1.6	1.3	0.6	1.2	1.3	1.4	1.3	1.4	1.4	0.7	1.6	0.8	0.8	0.4
Hearing aid user	1.1	1.2	4.3	-0.3	0.7	1.0	-1.6	-1.3	0.2	-0.1	-0.2	1.0	-0.5	-0.7	0.5	-0.5	-1.1	-1.4	-1.6	-1.8	-2.1	-1.2
Medication: Paracetamol	1.1	1.7	5.9	1.4	1.3	1.5	-0.8	-0.4	0.6	0.4	1.5	1.9	0.9	0.8	1.7	1.1	0.7	-2.1	-0.6	-1.1	1.1	-2.4
Bipolar Disorder or Schizophrenia	1.0	2.4	7.4	2.1	2.7	2.7	-2.3	-1.8	-0.2	-0.3	-0.6	1.3	0.2	0.2	1.5	0.5	-0.2	-2.1	-0.5	-1.7	-1.3	-2.3
Schizophrenia (2018)	1.0	2.1	4.4	1.1	1.8	1.7	-1.6	-1.7	-1.2	-1.4	-2.1	0.8	-1.1	-1.2	0.4	-1.1	-1.2	-1.8	-1.4	-1.1	-1.9	-1.9
Crohns Disease (2012)	1.0	1.6	3.7	-0.5	-1.6	-1.4	1.5	1.9	0.8	0.3	1.0	-1.3	1.0	1.1	0.6	0.8	1.3	1.8	1.8	1.4	0.9	1.3
Ulcerative Colitis	1.0	1.4	8.6	-1.7	-0.6	-0.4	2.0	1.6	-0.4	-0.5	-0.4	-0.1	-0.6	-1.0	-1.2	-1.4	-0.4	0.4	-0.2	2.9	1.5	0.1
Noisy workplace	1.0	1.2	4.7	1.1	0.3	0.0	-1.6	-1.6	-0.3	-0.5	-1.5	0.6	-0.3	-0.3	0.6	-0.4	-0.1	-1.3	-0.6	-1.8	-2.2	-1.6
Arm fat mass (right)	1.0	4.2	13.5	0.2	2.9	2.5	-2.4	-1.8	-1.9	-1.7	-0.4	2.4	-0.8	-1.7	1.0	-1.4	-1.5	-3.5	-2.5	-1.1	-1.3	-3.7
Hair/balding pattern: Pattern 4	1.0	2.4	7.3	0.2	1.4	1.7	-1.2	-1.8	-0.6	-1.2	-0.7	0.8	-1.8	-1.9	-1.5	-1.9	-2.1	-2.0	-2.7	-1.3	-1.3	-1.4
Emphysema/chronic bronchitis	1.0	1.1	3.2	-0.8	0.2	0.6	-0.8	-1.1	-1.0	-0.9	-0.4	0.4	-1.1	-1.6	-0.9	-1.2	-1.7	-1.0	-1.8	-0.7	-1.3	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.9	-0.1	-1.6	-1.7	0.7	1.1	1.4	1.6	1.3	-0.5	1.5	0.7	0.6	0.4	0.4	1.6	1.1	0.1	-0.3	1.1
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	5.1	-1.3	-1.6	-1.7	1.5	0.5	-0.2	-0.8	-0.3	-1.0	-0.1	-0.3	-0.9	-0.3	0.3	1.7	0.7	1.2	0.7	2.3
Leg fat-free mass (right)	1.0	5.4	18.1	-0.5	3.1	2.8	-2.0	-1.2	-2.2	-2.2	-0.6	3.4	-1.1	-2.1	0.7	-2.0	-1.9	-3.9	-3.1	-0.6	-1.1	-4.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	3.1	1.8	1.4	1.2	-1.3	-1.0	1.3	1.1	0.8	-0.7	1.1	1.0	1.4	0.8	0.3	-1.2	0.1	-0.6	0.2	-1.3
Leg predicted mass (right)	1.0	5.4	18.4	-0.5	3.1	2.8	-2.0	-1.2	-2.2	-2.2	-0.6	3.4	-1.0	-2.1	0.7	-1.9	-1.9	-3.9	-3.1	-0.5	-1.0	-4.3
Arm fat mass (left)	1.0	4.3	14.4	0.4	3.0	2.5	-2.4	-1.7	-1.8	-1.6	-0.3	2.5	-0.7	-1.6	1.1	-1.3	-1.5	-3.5	-2.5	-1.2	-1.3	-3.8
Age started oral contraceptive pill	1.0	1.3	3.6	-1.5	-1.3	-1.1	1.7	1.0	0.4	1.1	0.8	-1.0	0.2	0.5	-1.0	0.5	0.2	1.8	1.0	1.3	1.4	1.9
Basal cell carcinoma (self-reported)	1.0	1.2	5.2	-1.2	-0.6	-1.1	0.3	-0.1	-0.3	-1.4	-1.3	-2.3	-1.2	-1.1	-1.7	-1.3	-1.1	0.5	-1.0	0.1	-0.5	0.8
Alcohol drinker status: Previous	1.0	1.2	4.2	1.4	1.8	1.5	-1.4	-1.3	0.7	0.1	-0.6	1.1	0.3	-0.3	0.6	0.2	0.1	-2.0	-0.8	-0.1	-0.4	-2.0
Schizophrenia vs Biploar Disorder	0.9	1.2	4.0	-1.0	-0.8	-0.6	1.0	-0.1	-0.8	-1.0	-1.5	-1.2	-1.2	-1.8	-1.2	-2.0	-1.2	0.4	-1.1	0.8	-0.1	0.7
HbA1C	0.9	1.0	3.4	-1.8	-0.7	-0.3	0.9	-0.4	-0.9	-1.2	-0.6	-0.5	-1.4	-1.5	-1.6	-1.1	-1.4	0.1	-1.3	0.2	-0.0	0.1
Hearing difficulty/problems: Yes	0.9	1.3	3.7	1.9	1.5	1.1	-1.5	-0.7	0.3	0.4	-0.4	1.8	0.4	0.4	0.6	0.1	0.4	-1.7	-1.1	-1.9	-0.8	-1.5
Medication: Metformin	0.9	1.2	3.6	0.4	-0.8	-0.9	1.5	1.0	1.6	0.6	1.2	1.0	1.3	1.0	0.7	1.0	1.9	0.7	1.3	1.0	1.6	0.4
Townsend deprivation index at recruitment	0.9	1.3	4.3	1.4	1.9	1.5	-1.2	-0.8	-1.6	-0.4	-1.0	1.1	-0.5	-0.1	0.6	-0.3	0.1	-1.9	-0.8	-0.5	0.1	-2.1
Medication: Levothyroxine sodium	0.9	1.5	2.9	0.1	0.8	0.8	-1.2	-1.5	-1.2	-1.5	-1.2	1.4	-1.7	-1.5	-0.8	-1.2	-1.1	-1.7	-1.2	-0.9	-1.1	-1.4
Illnesses of siblings	0.9	1.3	3.1	0.5	-0.1	0.3	0.7	1.0	1.8	1.4	1.0	1.4	1.8	1.7	1.5	1.4	1.4	0.3	1.1	0.3	1.3	-0.3
Time employed in main current job	0.9	1.0	2.4	1.0	-1.1	-0.9	0.7	0.8	1.5	1.4	0.4	1.3	1.4	1.3	0.5	0.5	1.5	0.8	1.2	0.4	0.5	0.8
Qualifications: A levels/AS levels or equivalent	0.9	2.1	4.0	-0.4	-1.7	-1.7	2.0	2.0	1.5	0.8	1.3	-0.0	1.1	1.3	0.6	1.3	1.3	2.0	1.6	1.4	2.0	1.6
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	4.1	0.6	1.2	1.3	-1.7	-0.9	-0.2	-0.6	-0.3	-0.1	-0.0	-0.2	0.7	-0.1	-0.8	-1.4	-1.2	-2.0	-1.5	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	3.1	-0.3	1.3	0.8	-1.8	-1.2	-0.3	-1.1	-0.8	0.8	-0.8	-0.9	0.5	-0.8	-1.5	-1.1	-1.3	-0.8	-1.3	-1.0
Tinnitus: Yes, now most or all of the time	0.9	1.1	2.7	-1.1	0.2	0.1	-0.7	-0.8	-1.6	-1.2	-1.2	1.2	-1.4	-1.0	-1.3	-1.4	-0.9	-0.7	-1.5	-0.5	-1.1	0.3
Leg fat percentage (left)	0.9	3.3	8.9	0.5	2.9	2.7	-2.3	-2.3	-1.4	-1.5	-1.0	1.2	-0.9	-1.5	0.4	-1.2	-1.4	-3.0	-2.2	-1.3	-0.9	-2.8
Crohns Disease (2017)	0.8	1.7	4.5	0.1	-0.7	-0.9	1.6	2.1	1.8	0.9	1.0	-0.8	1.5	1.3	0.9	1.1	1.5	1.6	1.6	1.5	1.4	1.2
Body Mass Index (BMI) (2010)	0.8	1.1	4.2	0.3	1.0	1.0	-1.8	-0.5	-0.3	-0.2	0.6	1.3	0.2	0.1	1.8	0.0	-0.1	-1.3	-0.2	-2.1	-1.5	-1.5
Neuroticism (2016)	0.8	1.1	3.8	-0.1	1.3	0.8	-1.6	-0.8	-1.3	-1.2	-0.6	1.0	-0.5	-0.3	-0.4	-1.0	-0.5	-1.9	-1.4	-1.3	-0.7	-1.3
Schizophrenia (2014)	0.8	1.7	5.5	1.9	2.3	1.9	-2.0	-1.4	-0.6	-0.9	-1.3	0.7	-0.5	-0.5	0.6	-0.5	-0.4	-1.6	-0.6	-1.0	-1.6	-1.6
Type 2 Diabetes (T2D) (2018)	0.8	1.4	5.7	-1.9	-1.1	-1.0	2.2	1.5	0.1	-0.1	0.4	1.3	0.3	-0.1	-0.1	-0.1	0.6	0.8	0.1	2.2	2.4	0.6
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	3.1	-1.2	0.1	0.4	-0.1	-1.0	-1.0	-0.6	-0.7	0.9	-1.3	-1.4	-0.7	-0.5	-1.6	-0.9	-1.8	-0.3	-0.2	-0.3
Impedance of leg (right)	0.8	3.8	13.8	0.1	-2.7	-2.7	1.4	1.1	1.6	1.3	0.5	-3.7	1.1	1.6	-0.4	0.9	1.5	3.2	2.2	0.3	0.2	3.7
Alcohol usually taken with meals	0.8	1.3	4.2	-1.9	-1.0	-1.0	1.5	1.2	0.1	-0.6	0.3	-1.0	0.2	-0.6	-1.4	-1.0	-0.2	1.6	0.1	1.6	0.9	2.1
Qualifications: None of the above	0.8	1.8	6.5	0.2	-0.1	-0.2	-1.2	-2.0	-1.3	-1.5	-1.2	-0.1	-1.6	-1.8	-0.5	-1.3	-1.8	-1.0	-1.3	-1.5	-2.6	-0.7
Diabetes (self-reported)	0.8	1.2	3.8	-1.5	-1.7	-1.8	1.9	1.0	-0.5	-0.9	-0.8	-0.3	-0.6	-0.4	-0.5	-0.5	0.4	0.9	-0.2	1.7	1.3	1.1
Prospective memory result	0.8	1.0	2.9	-1.3	0.2	0.0	-0.7	-0.8	-1.6	-1.3	-1.2	0.7	-1.2	-1.2	-0.1	-1.1	-1.3	-0.6	-0.7	-0.5	-1.7	-0.8
Whole body fat mass	0.8	3.5	10.0	-0.1	2.6	2.3	-2.0	-1.6	-1.7	-2.0	-0.6	1.7	-0.7	-1.8	0.6	-1.7	-1.5	-3.1	-2.4	-0.8	-1.3	-3.2
Number of full sisters	0.8	1.0	3.4	-1.1	-1.4	-1.3	1.0	1.3	0.8	-0.2	0.2	-1.4	0.4	0.4	-0.1	-0.2	0.7	1.5	1.1	0.2	0.5	1.8
Age at last live birth	0.8	1.1	4.3	-0.9	-0.9	-0.8	1.6	2.0	0.6	0.4	1.2	0.6	0.8	0.8	0.4	0.6	0.8	1.1	0.2	0.8	2.1	1.1
Friendships satisfaction	0.8	1.0	4.0	0.8	1.4	1.3	-1.1	-0.3	0.1	0.2	-0.2	1.3	0.7	0.6	2.0	0.1	0.8	-1.4	-0.1	-0.6	-0.4	-2.0
Osteoporosis (self-reported)	0.8	1.0	5.3	0.2	0.8	0.9	0.8	0.5	0.8	1.0	-1.2	-1.0	0.3	0.3	-0.0	0.2	0.4	0.4	0.7	2.3	2.3	0.5
Illnesses of father: None of the above (group 1)	0.8	1.0	3.4	1.6	0.9	1.1	-1.5	-1.6	-0.1	-0.8	-0.4	-0.6	-0.1	-0.3	0.3	-0.3	-0.7	-0.8	-0.6	-1.5	-1.8	-1.1
Commuting to job workplace: Cycle	0.8	1.0	3.0	1.4	1.4	1.3	-1.5	-1.7	-0.4	0.2	-0.8	-0.3	-0.1	-0.0	0.8	0.7	-1.0	-0.7	-0.6	-1.2	-1.3	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	3.4	-1.3	-1.7	-1.8	1.7	0.8	1.0	-0.3	-0.7	-0.0	0.2	-0.2	0.3	-0.4	0.2	1.3	0.4	1.3	0.5	1.1
Cardiovascular Disease	0.7	2.4	10.2	1.2	0.6	1.1	0.9	1.7	1.1	1.7	1.6	0.4	1.8	1.8	1.8	1.9	2.1	0.4	1.4	1.3	3.2	0.0
Hand grip strength (left)	0.7	1.9	6.7	2.1	1.9	2.5	-1.9	-1.1	-0.5	-0.2	0.9	-0.0	1.0	1.2	1.2	1.1	0.2	-1.3	-0.4	-2.6	-0.8	-1.3
Number of treatments/medications taken	0.7	1.3	5.2	0.5	1.6	1.8	-0.7	-1.0	-0.7	-0.7	-0.5	0.6	-0.3	-0.8	-0.2	-0.5	-0.5	-2.2	-1.6	-0.0	1.0	-2.3
Chronic bronchitis/emphysema (father)	0.7	0.8	3.0	0.4	1.1	1.0	-1.5	-0.7	-0.4	-0.3	0.4	0.6	-0.1	-0.2	0.1	-0.4	-0.4	-1.5	-1.1	-1.7	-0.4	-1.4
Hair/balding pattern: Pattern 2	0.7	0.9	4.0	-2.0	-1.0	-1.0	1.2	1.2	-0.4	-0.2	0.0	0.6	0.3	0.2	0.2	0.4	-0.1	1.5	0.9	1.3	0.6	1.5
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.6	-1.0	-0.5	-0.7	0.2	-0.3	-0.2	-1.9	-1.0	-1.3	-0.8	-1.2	-1.1	-1.2	-0.6	0.6	-0.2	0.6	-1.2	1.0
Medication: Paracetamol	0.7	1.1	5.2	0.6	0.9	0.8	-0.5	0.0	0.7	0.6	1.5	1.2	0.8	0.6	1.3	1.0	0.5	-1.9	-0.8	-0.9	0.9	-2.3
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	8.4	0.0	-0.2	-0.4	-1.0	-1.1	-0.6	-1.3	-1.3	0.2	-0.8	-0.9	-1.2	-1.4	-1.0	-0.3	-1.0	-1.2	-2.9	0.2
Medication: Amlodipine	0.7	0.9	2.4	1.4	-0.6	-0.4	0.5	0.4	1.6	1.3	0.5	1.3	1.1	0.9	1.4	0.7	1.4	0.7	1.0	0.1	0.7	0.4
Eye problems/disorders: None of the above	0.7	0.8	3.5	0.3	0.2	0.3	0.3	0.7	1.1	1.9	1.1	-1.1	1.3	0.9	0.7	0.7	0.3	1.1	1.2	-0.0	0.5	1.0
Migraine (self-reported)	0.7	0.9	3.8	1.2	2.0	1.6	-1.4	-0.9	0.1	0.1	-0.4	1.3	0.3	0.3	0.2	-0.0	0.1	-1.3	-0.2	-1.1	0.2	-1.0
Medication: Allopurinol	0.7	1.0	4.7	0.9	0.6	0.7	-1.4	-1.5	0.1	-0.0	0.3	-0.1	-0.0	-0.1	0.2	-0.1	-0.3	-1.4	-0.8	-2.2	-1.4	-1.9
Leg pain on walking	0.7	0.9	3.2	-0.4	0.2	0.3	-1.1	-1.1	0.2	-0.5	0.9	1.4	0.1	-0.4	1.4	-0.2	-0.7	-0.9	-1.0	-1.8	-1.4	-1.1
Illnesses of siblings: Diabetes	0.7	0.8	3.8	-1.5	-1.5	-1.1	0.9	1.0	0.3	0.7	2.0	-0.8	-0.1	-0.1	-0.9	0.5	-0.1	0.8	0.1	0.6	0.7	1.0
Diabetes diagnosed by doctor	0.7	1.2	4.5	-1.5	-1.4	-1.3	2.1	1.1	-0.0	-0.5	-0.0	-0.0	0.2	0.0	-0.2	0.1	1.0	1.0	0.6	2.1	2.0	0.9
Breast cancer (self-reported)	0.7	0.9	3.0	0.5	-1.2	-0.8	-0.0	-0.4	0.7	0.4	1.1	-0.3	1.0	1.5	0.7	1.7	1.1	0.9	1.1	-1.0	-0.2	1.0
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.7	-0.6	0.1	-0.3	-0.6	-1.1	-0.4	-1.7	-1.3	-0.4	-1.0	-1.4	-0.5	-0.9	-1.2	-0.9	-1.1	-0.9	-1.3	-0.8
Medication: Bendroflumethiazide	0.7	1.1	3.1	1.2	-0.3	0.1	0.4	0.5	1.6	1.8	1.7	-0.4	1.4	1.3	0.8	1.5	1.0	0.2	0.4	-0.6	1.7	-0.1
Risk taking	0.7	1.1	2.7	-0.9	0.1	-0.3	-0.7	-0.7	-1.3	0.3	1.3	1.6	-0.6	-0.9	-0.0	-0.6	-1.1	-1.6	-1.6	-1.0	-1.3	-1.6
Heart disease (siblings)	0.7	0.9	3.4	0.2	-0.1	-0.3	-1.2	-1.2	-0.9	-1.2	-1.1	0.4	-0.8	-0.8	-0.5	-0.9	-0.7	-0.6	-0.9	-1.4	-1.9	-0.0
Pack years of smoking	0.7	1.0	2.8	0.2	-0.1	-0.4	-1.0	-0.8	-1.4	-1.5	-1.6	0.2	-1.3	-1.0	-0.4	-0.8	-1.1	-0.9	-1.0	-0.7	-1.7	-0.8
Alzheimer’s Disease (in father)	0.6	0.7	2.3	0.4	-1.1	-1.2	0.3	0.1	0.6	-0.8	-0.1	-1.5	0.4	0.3	0.8	0.7	0.8	1.0	1.3	0.1	-1.0	0.7
Ever used hormone-replacement therapy (HRT)	0.6	0.8	3.7	0.6	0.3	0.4	-1.2	-1.9	-0.2	-0.7	-1.0	-0.7	-0.3	-0.6	-0.3	-0.4	-0.8	-0.5	-0.6	-1.3	-1.8	-0.3
Pack years adult smoking proportion	0.6	0.9	2.0	0.3	0.0	-0.3	-1.1	-0.6	-1.2	-1.3	-1.2	0.7	-1.1	-0.7	-0.1	-0.5	-0.8	-1.2	-1.0	-0.9	-1.4	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	4.5	-1.2	0.4	0.4	-0.2	-0.1	-1.4	-2.1	-0.9	-0.5	-0.8	-0.9	-0.6	-1.2	-0.6	-0.6	-0.8	0.3	0.0	-0.3
Lung cancer (father)	0.6	0.7	3.5	1.9	0.3	0.2	-0.8	-0.3	0.4	0.7	0.2	1.0	0.6	1.0	1.6	1.0	0.4	-0.5	-0.6	-1.1	-0.2	-0.8
Illnesses of mother	0.6	0.7	2.7	-0.7	-0.3	-0.6	0.9	0.4	1.0	0.6	0.3	-1.7	0.1	0.2	-0.7	0.2	-0.2	1.2	0.7	1.5	0.6	1.4
Exposure to tobacco smoke at home	0.6	0.7	2.1	-0.2	1.0	1.0	-0.2	0.5	-1.5	-0.0	-0.4	1.0	-0.8	-0.5	0.4	-0.4	-0.1	-1.3	-0.8	0.8	1.3	-1.3
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	5.2	-0.4	0.2	0.0	1.0	1.8	0.5	0.8	0.4	1.4	0.4	0.6	0.4	0.5	0.8	0.4	0.4	1.8	2.3	0.5
High blood pressure (siblings)	0.6	0.9	2.7	-0.1	0.4	-0.0	-0.1	-0.7	-1.6	-1.6	-1.1	-0.2	-1.4	-1.4	-1.6	-1.0	-0.9	-0.6	-1.0	0.4	-0.0	-0.3
Comparative height size at age 10	0.6	3.2	8.6	-1.4	0.4	1.0	-1.2	-1.7	-2.4	-2.6	-0.7	-0.7	-2.0	-2.3	-1.0	-2.1	-2.5	-1.9	-2.9	-1.0	-1.6	-1.8
Supplements: Vitamin C	0.6	0.8	3.5	0.0	0.1	0.6	-0.9	-1.3	-0.1	-0.2	0.4	1.1	-0.4	-0.7	-0.2	0.2	-1.6	-0.6	-1.2	-1.9	-1.1	-0.6
Average weekly red wine intake	0.6	0.8	2.3	-0.8	-0.7	-0.8	1.1	1.4	0.1	0.4	1.3	-1.0	0.6	0.1	-0.8	-0.2	0.2	1.2	0.7	1.4	0.3	1.5
Fractured/broken bones in last 5 years	0.6	0.8	3.0	-1.4	-1.5	-1.7	1.2	0.7	0.7	0.9	-0.1	-1.0	-0.2	-0.2	-0.8	-0.3	-0.5	1.2	-0.1	0.3	-0.0	0.9
Unable to work because of sickness or disability	0.6	0.8	3.3	-0.8	-0.7	-0.8	-0.7	-1.5	-0.4	-0.9	-0.8	-0.5	-0.8	-1.0	-0.6	-0.6	-1.2	-0.4	-1.1	-0.7	-1.8	0.1
Intelligence (Savage-Jansen 2018)	0.5	1.4	5.0	1.6	-0.2	-0.7	0.8	1.3	0.4	0.7	1.1	1.6	1.1	1.4	1.9	1.0	2.2	0.3	1.5	0.3	1.5	-0.3
Reaction Time	0.5	0.9	3.7	0.4	0.4	0.6	-0.6	-1.5	0.1	-0.3	-1.3	1.9	-1.0	-0.8	-0.1	-0.3	-0.1	-1.5	-0.9	-0.8	-0.3	-1.6
Diabetes (mother)	0.5	0.6	2.3	-0.1	-1.4	-1.2	1.5	1.4	-0.2	0.2	0.6	-0.0	0.5	-0.1	0.0	-0.2	0.9	0.9	0.5	1.1	0.2	0.5
Maternal smoking around birth	0.5	0.7	2.5	0.2	0.1	0.2	0.2	0.7	1.0	0.9	1.0	-0.1	1.1	0.9	1.6	0.8	0.9	0.2	1.2	0.8	0.6	-0.7
Trunk fat mass	0.5	2.3	5.4	-0.4	1.9	1.6	-1.3	-1.1	-1.6	-2.2	-0.6	0.9	-0.6	-1.8	0.3	-1.8	-1.4	-2.3	-2.1	-0.2	-1.1	-2.3
Mouth/teeth dental problems	0.5	0.8	2.4	-1.5	-0.9	-1.3	1.1	0.8	-0.0	-0.5	-0.1	1.5	-0.4	-0.4	-0.8	-0.9	-0.0	1.1	-0.0	1.0	0.2	1.4
Falls in the last year	0.5	0.7	5.9	-0.6	-0.7	-0.6	0.9	0.6	-1.0	-2.4	0.1	-0.8	-0.6	-0.9	-1.0	-0.8	0.0	0.1	-0.3	0.9	0.7	0.4
Depression (self-reported)	0.5	0.6	2.7	0.5	1.0	0.6	-0.7	-0.4	-1.3	-0.9	-1.0	0.1	-0.3	-0.5	0.7	-0.6	0.1	-1.2	-0.3	-0.2	-0.2	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	5.5	0.6	0.2	0.7	-0.4	1.1	0.9	1.3	1.9	0.2	2.1	2.4	2.0	1.7	1.1	0.7	1.0	-0.9	0.7	0.4
Breastfed as a baby	0.5	0.6	1.4	-0.7	-0.5	-0.6	1.2	0.7	0.9	0.4	0.9	0.8	0.5	0.1	0.5	0.6	0.0	1.1	0.3	1.2	1.1	0.8
Medication: Ibuprofen	0.5	0.5	2.5	0.5	0.6	0.6	-0.6	-0.3	0.2	-0.5	0.1	0.1	0.1	0.1	1.1	0.1	-0.5	-0.9	-1.1	-1.6	-0.5	-1.6
Qualifications: nursing, teaching	0.5	0.8	3.4	-1.6	-0.1	-0.0	0.5	0.2	-1.1	-0.6	-0.3	0.4	-1.1	-1.0	-1.8	-0.9	-1.0	0.2	-0.7	1.1	0.4	0.7
Eye problems/disorders: Cataract	0.5	0.6	1.9	0.8	-1.0	-0.8	0.3	0.7	0.7	0.2	0.6	1.4	1.0	0.9	0.8	0.8	1.0	0.5	0.9	0.2	-0.1	0.1
Average weekly champagne plus white wine intake	0.5	0.7	3.2	-0.6	1.0	1.1	-1.0	-0.4	-0.8	-0.6	0.2	-1.8	-0.7	-0.6	-0.1	-0.2	-1.3	-0.6	-0.6	-0.8	-0.7	-0.6
Number of operations (self-reported)	0.5	0.7	5.1	0.3	0.7	0.9	-1.0	-0.7	0.6	0.6	0.8	-2.2	0.2	0.2	0.7	0.3	-0.7	-0.6	-0.7	-1.1	-0.5	-0.8
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.7	-1.2	0.1	0.2	0.4	-0.2	-0.9	-1.0	-0.6	-0.1	-1.0	-1.3	-1.1	-1.3	-0.5	-0.6	-0.6	1.2	0.2	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.7	-0.9	-0.5	-0.9	-0.3	-0.5	-0.8	-0.6	-0.6	-1.0	-0.9	-1.3	-0.6	-1.1	-1.3	0.0	-0.6	0.5	-0.8	0.5
Alzheimer’s Disease (in mother)	0.4	0.4	1.2	-0.2	0.6	0.4	-0.2	-0.1	-0.7	-1.1	-0.9	-0.1	-0.5	-0.7	-0.7	-0.9	-0.1	-1.1	-0.9	0.7	0.5	-0.8
Ulcerative Colitis (UC)	0.4	0.7	2.9	-1.3	-0.6	-0.6	1.7	1.3	0.2	-0.5	-0.4	0.4	-0.1	-0.3	-0.8	-0.9	0.1	0.6	-0.3	1.5	1.3	0.6
Breast Cancer	0.4	0.9	2.7	-0.6	0.4	0.3	-0.5	-0.5	-1.6	-1.1	-0.8	-1.4	-1.3	-1.2	-1.3	-0.8	-1.4	-0.5	-0.8	0.3	-0.7	-0.2
Blood Eosinophil Count	0.4	2.8	8.0	-0.6	-1.6	-1.7	2.6	2.8	0.5	1.6	2.3	0.1	1.0	0.7	0.3	1.2	1.2	1.7	1.5	2.4	2.7	1.2
Waist Hip Ratio (WHR)	0.4	1.7	8.6	0.1	-1.5	-1.2	-0.1	0.1	-1.2	-1.3	-2.9	-1.1	-1.7	0.7	1.3	0.3	0.7	1.5	1.3	-1.0	-1.4	1.5
Lung FEV1/FVC ratio	0.4	1.8	6.6	1.7	1.2	1.3	-0.8	-0.1	0.7	1.5	2.6	-0.6	1.6	1.2	1.4	1.1	1.4	-1.3	0.5	-1.1	1.0	-1.9
Diabetes (father)	0.4	0.5	2.0	-0.9	-1.4	-1.0	0.9	0.6	0.5	0.7	1.0	0.9	0.2	-0.1	0.3	0.0	0.4	0.2	0.2	0.5	0.3	-0.5
High blood pressure	0.4	1.2	3.2	1.8	1.3	1.5	-0.4	-0.3	0.1	1.0	0.5	1.3	0.9	0.9	1.3	1.3	0.9	-1.1	-0.2	-0.0	1.8	-1.6
Had other major operations	0.4	0.5	2.6	0.2	-0.0	0.3	0.2	0.6	0.4	1.0	1.6	-1.2	0.5	0.7	0.7	0.7	0.0	-0.0	-0.2	-0.7	0.7	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	2.6	1.4	-0.4	-0.4	0.7	1.6	0.9	1.4	1.2	-0.0	1.3	1.1	0.9	0.6	1.1	0.7	0.7	0.1	0.5	0.9
Pain all over the body in last month	0.4	0.4	1.4	-1.1	-0.0	-0.0	-0.5	-0.4	-0.6	-1.0	-0.7	-1.0	-0.5	-0.6	-0.5	-0.8	-0.4	-0.2	-0.5	-0.3	-1.2	0.0
Arm fat percentage (right)	0.4	1.7	5.7	0.1	1.9	1.5	-1.3	-1.1	-1.2	-1.3	-0.3	1.1	-0.4	-1.4	0.6	-1.1	-1.1	-2.2	-1.6	-0.3	-0.7	-2.4
Hair/balding pattern: Pattern 3	0.4	0.5	4.1	0.8	-0.0	0.1	-0.5	-0.5	0.6	0.6	0.7	-2.0	0.2	0.8	0.4	0.7	0.5	-0.3	-0.0	-1.4	-0.2	-0.5
Peak expiratory flow (PEF)	0.4	0.8	3.0	0.2	-0.4	-0.3	0.5	1.7	0.5	0.7	1.5	-0.6	1.6	1.2	1.1	0.8	0.9	1.0	0.8	0.6	0.4	0.6
Loud music exposure frequency	0.4	0.5	1.5	1.1	0.7	0.3	-0.7	0.2	0.6	0.8	0.5	0.7	1.1	0.5	1.2	0.2	0.1	-0.7	-0.1	-0.8	-0.5	-0.9
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	4.4	0.0	0.6	0.9	-0.6	-0.7	-0.8	-0.1	-0.7	-2.1	-0.4	-0.5	0.1	-0.1	-0.9	-0.3	-0.1	-0.1	-0.9	-0.8
Headache pain in last month	0.4	0.6	3.0	0.3	1.5	1.5	-0.9	-0.6	-0.2	0.2	-0.1	0.1	0.1	-0.1	0.6	-0.1	-0.4	-1.3	-0.6	-0.5	-0.2	-1.7
Body fat percentage	0.4	1.4	3.2	-0.3	1.5	1.1	-1.0	-1.1	-1.2	-1.8	-0.7	0.3	-0.5	-1.5	0.2	-1.5	-1.1	-1.8	-1.6	-0.0	-0.9	-1.8
Medication for pain relief, constipation, heartburn	0.4	0.6	2.2	0.0	-1.1	-0.9	0.7	0.3	0.5	0.9	-0.1	-1.1	0.1	0.4	-0.9	0.0	0.5	1.5	1.2	0.4	-0.4	1.3
Overall health rating	0.4	0.8	3.0	-0.8	-1.3	-1.0	-0.4	-1.1	-0.8	-1.7	-0.9	-1.2	-0.5	-1.1	-0.2	-0.9	-0.3	-0.4	-0.5	-0.3	-1.4	-0.2
Chest pain or discomfort	0.4	0.5	2.0	0.8	-0.2	-0.3	-0.1	0.1	1.4	0.9	0.3	-0.9	1.2	0.5	1.4	0.4	0.5	-0.1	0.3	-0.1	-0.9	-0.6
Had major operations	0.4	0.5	1.8	-0.8	1.0	1.4	-0.8	-0.3	-0.6	-0.2	1.0	-0.3	0.3	-0.1	0.3	0.6	-0.4	-0.9	-0.8	0.2	0.7	-0.9
Hypertension (Self-reported)	0.4	1.1	3.5	1.5	1.3	1.5	-0.4	-0.2	0.0	0.8	0.4	1.2	0.8	0.8	1.2	1.1	0.9	-1.1	-0.4	-0.0	1.9	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.3	-0.7	0.1	-0.2	0.6	0.3	-0.5	-0.6	-0.9	-1.1	-1.3	-1.1	-1.5	-1.2	-0.7	-0.3	-0.8	1.1	0.3	-0.2
Back pain experienced in last month	0.4	0.5	1.9	0.7	0.4	0.9	-0.4	-0.1	1.0	0.2	0.8	-0.4	1.1	0.9	1.4	1.3	0.2	-0.4	-0.3	-0.5	0.5	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	4.0	0.4	-0.5	0.5	-0.1	0.2	0.3	1.8	2.0	0.1	0.6	1.5	0.3	1.8	0.3	0.7	0.7	-1.4	0.4	0.3
Alcohol drinker status: Never	0.4	0.4	3.3	0.7	-0.7	-0.4	0.4	0.5	-0.2	1.1	-0.2	-1.8	-0.2	-0.1	0.1	-0.1	0.3	0.6	1.0	0.7	-0.6	0.4
Irritable Bowel Disease (IBD)	0.3	0.7	2.9	-0.7	-0.6	-0.7	1.7	1.7	0.9	0.0	0.1	-0.2	0.7	0.3	0.0	-0.4	0.7	0.9	0.4	1.5	1.1	0.7
Primary Biliary Cirrhosis	0.3	0.4	1.2	-0.4	-0.1	-0.2	0.6	0.1	-0.6	-0.6	-0.8	-0.7	-1.1	-1.0	-1.0	-0.8	-0.7	0.3	-0.2	1.0	0.4	0.5
Triglycerides	0.3	0.4	1.4	-1.1	-0.4	-0.3	0.4	-0.1	-0.3	-1.2	-0.5	1.2	-0.8	-0.4	0.2	-0.3	-0.5	-0.7	-1.0	0.3	0.3	-0.6
Systolic Blood Pressure	0.3	1.5	3.8	-0.8	-1.4	-1.3	1.9	1.0	-1.3	-0.9	-1.8	1.3	-1.2	-0.3	-1.3	-0.8	0.6	1.3	0.3	1.4	1.4	1.4
Hypothyroidism (self reported)	0.3	0.7	3.3	-0.2	0.8	0.7	-0.4	-0.0	-0.6	-0.6	-0.4	1.8	-0.7	-0.2	-0.1	-0.6	-0.2	-1.5	-1.0	-0.3	0.2	-1.7
Tanning	0.3	3.9	6.7	-0.5	2.0	2.1	-2.5	-2.2	-2.2	-1.5	-1.0	0.7	-1.6	-2.1	-0.9	-1.5	-2.5	-2.5	-2.6	-2.2	-2.5	-2.0
Systolic blood pressure, automated reading	0.3	0.9	4.1	0.1	-1.3	-1.0	1.6	0.8	-1.2	-0.2	-0.7	2.0	-1.1	-0.2	-1.1	-0.1	0.6	0.7	0.5	0.8	1.2	0.6
Vitamin and mineral supplements	0.3	0.4	1.5	0.1	-0.2	-0.7	0.5	0.8	-0.5	-0.6	-0.7	-0.3	-0.2	-0.0	-0.5	-0.9	1.0	0.5	0.7	1.2	0.2	1.0
Hand grip strength (right)	0.3	0.8	3.5	1.9	1.2	1.1	-0.6	0.2	-0.1	-0.0	0.9	-1.4	1.1	1.2	1.2	0.8	0.7	-0.4	0.2	-1.1	-0.1	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.8	1.4	0.0	0.1	0.6	1.4	0.7	0.8	0.9	0.2	1.1	0.9	1.1	0.7	1.0	0.5	0.8	0.2	0.7	0.7
Serious illness, injury or assault to yourself	0.3	0.4	1.1	-0.5	-0.0	-0.2	-0.2	-0.7	-0.8	-0.4	0.0	0.6	-0.6	-0.8	-0.9	-0.4	-0.8	-0.9	-1.0	0.1	-0.0	-0.7
Multivitamins +/- minerals	0.3	0.4	2.3	0.3	0.1	0.3	-0.6	-0.8	0.5	0.5	0.6	-0.1	0.4	0.4	0.9	0.9	-0.1	-0.5	-0.0	-1.5	-0.6	-1.1
Father’s age at death	0.3	0.4	1.5	0.1	-0.1	0.2	0.2	-0.8	0.5	-0.1	-0.8	1.2	-0.9	-1.0	-1.0	-0.7	-0.7	0.0	0.0	0.5	-0.4	0.0
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	3.4	0.5	0.0	0.4	0.0	1.2	0.7	1.3	1.3	0.5	1.7	1.8	1.5	1.1	0.8	0.8	0.8	-0.4	0.6	0.6
Pulse rate	0.3	0.5	2.7	0.2	-1.6	-1.1	0.7	0.4	-0.1	0.4	0.4	-1.0	0.5	0.6	-0.1	0.8	0.6	1.2	1.0	0.3	-0.0	0.6
Mouth/teeth dental problems: Dentures	0.3	0.6	2.0	1.2	0.9	1.3	-1.2	-1.4	0.2	0.3	-0.1	-0.4	0.2	0.1	0.1	0.4	-0.2	-1.1	-0.4	-1.0	-0.1	-0.9
Medication: Lansoprazole	0.3	0.3	1.6	0.1	0.7	0.7	-0.9	-0.7	0.3	-0.7	-0.1	1.3	0.4	0.4	0.5	0.2	-0.1	-0.3	0.1	0.5	-0.1	-0.1
Gout (self-reported)	0.3	0.4	1.4	0.6	0.6	0.6	-1.0	-0.6	0.4	0.1	0.2	-0.9	0.2	0.1	0.4	0.1	-0.1	-0.6	-0.3	-1.1	-0.5	-1.2
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.3	-0.5	-0.6	-0.5	0.5	0.1	-0.8	-0.8	-0.8	-0.3	-1.1	-0.7	-0.6	-0.4	-0.4	0.4	0.1	0.7	-0.0	-0.1
Qualifications: College or University degree	0.3	1.0	4.2	-0.9	-0.4	-0.4	1.0	1.6	1.0	0.8	1.4	1.0	0.7	1.1	0.3	0.7	0.7	1.0	0.6	1.0	2.0	0.8
Mean time to correctly identify matches	0.3	0.6	3.0	0.2	-0.2	0.0	-0.2	-1.3	0.5	-0.1	-1.2	1.7	-1.1	-0.9	-0.4	-0.4	-0.4	-0.8	-0.7	-0.5	-0.4	-0.9
Medication: Aspirin	0.3	0.5	1.9	-0.2	0.9	0.8	0.1	-0.2	-0.6	-1.2	-1.2	0.4	-0.4	-0.3	-0.0	-0.1	0.5	-0.3	-0.1	1.1	1.4	-0.0
Knee pain experienced in last month	0.3	0.5	1.9	0.2	-0.8	-0.2	0.1	-1.4	-0.3	-0.8	-1.1	-0.2	-0.8	-0.8	-0.7	-0.6	-0.3	-0.3	-0.5	-0.6	-1.3	-0.5
Illnesses of father: Heart disease	0.3	0.4	2.0	0.7	0.6	0.6	-0.3	0.5	0.1	0.9	0.4	0.3	0.8	1.0	0.7	0.8	1.4	-0.2	0.9	0.2	0.5	-0.1
Arm fat percentage (left)	0.3	1.3	5.2	0.2	1.8	1.3	-1.1	-0.6	-0.9	-1.1	-0.1	1.3	-0.2	-1.1	0.8	-1.0	-0.8	-2.0	-1.4	0.0	-0.4	-2.3
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.2	0.6	0.0	-0.6	0.0	1.0	0.3	0.4	0.7	-0.0	0.6	1.1	0.6	1.0	0.9	-0.0	0.2	-0.2	0.7	0.2
Medication: Aspirin	0.3	0.4	2.2	0.2	0.6	0.6	0.3	0.1	-0.1	-0.7	-1.0	0.3	0.1	0.2	0.3	0.2	0.9	0.2	0.6	1.0	1.5	0.4
Mother’s age at death	0.3	0.4	1.2	0.8	0.3	0.5	-0.1	0.3	0.8	0.7	0.7	-0.8	1.1	0.9	0.9	0.6	0.1	0.1	0.1	-1.0	-0.2	-0.4
Vascular/heart problems diagnosed by doctor	0.3	0.8	3.6	-1.6	-1.1	-1.2	0.1	0.2	-0.1	-0.8	0.0	-0.4	-0.8	-0.9	-1.1	-1.2	-1.0	0.5	-0.1	-0.2	-1.9	0.9
Alzheimer’s Disease (including proxy)	0.2	0.3	2.2	0.3	-0.1	-0.5	0.2	-0.2	0.1	-1.1	-1.1	-1.5	-0.3	-0.3	0.0	-0.2	0.4	-0.1	0.3	0.7	-0.6	-0.2
Ovarian Cancer	0.2	0.3	2.2	0.7	0.2	-0.2	-0.3	0.1	-0.2	-0.7	0.1	0.2	1.0	0.4	1.5	0.2	0.9	0.1	0.8	-0.6	-0.3	0.0
Blood Red Count	0.2	1.8	10.7	-1.6	-0.3	-0.3	-1.2	-1.1	-1.0	-0.8	-0.4	0.0	-0.7	-1.1	-0.6	-1.3	-2.3	0.6	-1.5	-1.6	-3.3	1.2
Heel T-Score	0.2	1.4	6.4	2.5	1.4	1.4	-1.4	-0.7	0.1	0.8	0.2	0.9	0.2	-0.0	0.8	0.1	-0.3	-1.8	-1.4	-1.4	-0.6	-1.8
Height	0.2	3.4	10.2	-3.1	-1.2	-1.1	1.2	0.7	-2.0	-2.4	-0.5	-1.9	-1.6	-2.4	-2.4	-3.2	-1.8	0.6	-1.9	1.6	-1.1	1.4
Chronotype (morning person)	0.2	0.4	1.4	-0.5	0.4	0.2	-0.2	0.2	-1.0	-1.0	-1.2	0.2	-0.8	-0.7	-0.8	-1.2	-0.1	-0.3	-0.4	0.0	-0.1	0.0
Medication for hormone replacement therapy	0.2	0.3	0.7	0.3	0.6	0.4	-0.7	-0.8	-0.2	-0.5	-0.6	-0.6	-0.2	-0.5	-0.3	-0.2	-0.5	-0.5	-0.4	-0.5	-0.6	-0.6
Trunk fat percentage	0.2	0.8	3.4	-0.9	0.5	0.1	0.1	-0.2	-1.0	-1.8	-0.6	-0.5	-0.4	-1.5	-0.3	-1.7	-0.8	-0.7	-1.2	1.0	-0.4	-0.7
Had menopause	0.2	0.3	1.4	0.8	0.1	0.7	-0.5	-1.2	0.1	0.5	0.3	-0.7	0.3	0.2	-0.1	0.4	0.3	-0.2	0.4	-0.5	-0.5	-0.5
Medication: Ramipril	0.2	0.3	1.6	0.8	0.5	0.3	-0.3	0.1	-0.1	0.4	0.8	-0.2	0.6	0.2	0.8	0.1	0.4	-0.7	0.1	0.5	0.3	-1.3
Pulse wave reflection index	0.2	0.3	0.9	-0.8	-0.8	-1.0	0.7	0.3	0.4	-0.8	0.6	0.1	0.0	-0.3	-0.2	-0.7	0.1	0.3	0.1	0.3	-0.3	0.2
Age at first live birth	0.2	0.3	0.9	-0.6	-0.1	-0.0	0.9	0.9	0.5	-0.8	-0.3	-0.3	0.4	0.1	0.6	-0.1	-0.1	0.5	-0.6	0.6	1.0	0.4
Angina (self-reported)	0.2	0.3	0.9	0.1	-0.6	-0.7	0.2	-0.2	0.7	-0.1	-0.2	-0.4	0.4	0.6	0.9	0.8	0.4	0.7	0.4	-0.5	-0.2	0.5
Medication: Omeprazole	0.2	0.2	1.3	-0.1	-0.2	-0.5	-0.4	-0.4	-0.1	0.1	-0.1	-1.2	-0.1	-0.6	0.3	-0.4	-0.7	-0.1	-0.2	-0.1	-0.7	0.1
Heart disease (mother)	0.2	0.2	1.2	-0.1	-0.1	-0.2	-0.6	-0.2	-1.1	-0.1	0.5	0.2	-0.6	-0.2	-0.5	-0.1	0.1	-0.3	0.1	-0.7	-0.4	-0.1
Pulse rate, automated reading	0.2	0.7	2.5	0.5	-1.6	-1.3	0.5	0.1	-0.0	0.5	-0.2	-0.6	1.2	1.0	0.6	0.5	1.2	0.9	1.1	-0.4	-0.8	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	2.7	-0.4	0.7	0.8	-0.6	-0.3	0.1	-0.4	0.2	-1.5	1.1	0.3	1.7	0.1	-0.3	-0.4	-0.3	-0.6	-0.3	-0.9
Medication for cholesterol	0.2	0.4	1.5	0.5	0.5	0.5	-0.9	-0.4	0.3	0.4	1.1	0.6	0.4	0.6	0.4	0.7	-0.1	-0.3	0.1	-1.2	-0.5	-0.1
Mineral and other dietary supplements	0.2	0.3	0.9	0.6	0.4	0.1	-0.3	0.7	-0.1	0.1	0.1	0.4	0.8	0.8	0.8	-0.1	0.9	0.3	0.6	0.4	-0.4	0.8
Wears glasses or contact lenses	0.2	0.2	0.6	0.1	-0.3	-0.6	0.7	0.1	0.7	-0.7	-0.2	-0.4	0.3	0.3	0.5	0.2	0.6	0.6	0.4	0.6	-0.0	0.6
Medication: Blood pressure	0.2	0.4	1.3	0.2	0.4	0.4	-0.5	-1.0	-0.3	-0.4	-1.1	0.8	-0.5	-0.6	-0.1	-0.6	-0.6	-0.8	-1.0	-0.4	-0.3	-0.8
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.9	-0.0	-0.1	0.1	-0.3	-0.7	0.1	0.4	0.5	0.6	-0.5	-0.2	-0.5	0.4	-0.9	-0.2	-0.6	-1.4	-0.2	-0.4
Medication: Lisinopril	0.2	0.3	1.1	-0.2	0.5	0.4	0.2	-0.5	-0.6	-0.2	-0.4	-0.5	-1.0	-0.5	-0.4	0.1	-0.7	-0.2	-0.6	0.4	1.0	-0.0
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.9	1.4	0.1	-0.3	-0.1	0.4	-0.1	0.3	0.4	1.1	0.1	0.8	0.2	0.4	1.1	-0.1	0.5	-0.7	0.3	-0.2
Coronary Artery Disease (CAD)	0.1	0.2	0.6	0.5	-0.4	-0.3	0.2	-0.2	-0.1	-0.3	0.6	-0.0	-0.3	-0.3	0.5	0.6	0.4	-0.1	0.6	0.0	-0.2	-0.8
Blood Platelet Count	0.1	0.9	2.7	-1.5	-1.6	-1.4	1.3	1.1	-1.4	-0.1	0.3	-0.0	-0.6	-0.3	-0.8	-0.2	0.4	1.1	0.8	0.9	0.8	1.1
Blood White Count	0.1	0.6	2.2	-1.1	0.2	0.8	-0.6	-1.0	-0.2	0.2	1.1	1.2	-0.1	0.0	0.3	1.1	-0.7	-0.8	-0.8	-1.5	0.4	-0.8
Lung FVC	0.1	0.5	1.6	-0.4	-0.7	-0.3	0.1	-0.2	-0.2	0.4	-1.3	1.0	-1.2	0.2	-1.3	0.2	-0.5	0.6	-0.3	0.1	0.5	1.2
Angina	0.1	0.1	0.5	0.0	-0.4	-0.5	-0.0	-0.4	0.3	-0.3	-0.4	-0.4	0.1	0.2	0.7	0.5	0.0	0.4	0.1	-0.7	-0.3	0.3
Medication: Co-codamol	0.1	0.1	0.6	-0.8	0.1	0.1	0.2	-0.1	0.3	-0.0	-0.2	-0.3	0.2	-0.4	-0.1	-0.5	-0.2	0.0	0.3	0.5	0.1	0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	0.3	0.3	0.4	-0.5	-0.1	-0.4	0.5	0.2	-0.4	-0.2	0.2	-0.4	0.2	0.1	-0.2	0.3	0.0	0.4	0.1
Qualifications: CSEs or equivalent	0.1	0.2	0.6	0.2	-0.4	-0.3	0.8	0.4	0.2	0.0	-0.0	-0.2	0.3	-0.1	0.4	-0.2	0.8	-0.2	0.0	0.5	0.3	-0.7
Medication: Atenolol	0.1	0.2	1.4	-0.1	0.2	-0.1	0.5	0.5	0.1	0.0	-0.4	-0.5	-0.0	0.1	0.1	0.3	0.2	0.4	0.2	0.6	1.2	0.6
Sitting height	0.1	0.8	2.8	-1.3	0.2	0.4	-0.2	0.2	-1.6	-1.4	0.1	1.0	-0.1	-1.1	-0.1	-1.7	-1.0	-0.3	-1.1	0.4	-1.0	-0.5
Forced vital capacity (FVC)	0.1	0.3	1.7	0.1	0.5	0.9	-0.5	0.4	-0.1	0.2	0.1	1.3	0.7	0.9	1.1	0.4	-0.1	0.2	0.1	-0.4	-0.1	0.3
Standing height	0.1	1.5	5.1	-1.7	0.4	0.5	-0.5	-0.1	-1.6	-2.0	-0.1	-0.5	-0.6	-1.7	-0.5	-2.2	-1.8	-0.8	-1.8	0.1	-1.3	-0.5
Forced vital capacity (FVC), Best measure	0.1	0.3	1.3	-0.1	0.5	1.0	-0.7	0.3	-0.3	0.0	0.3	0.4	0.7	1.1	1.0	0.5	-0.1	0.3	0.0	-0.7	-0.0	0.5
Exposure to tobacco smoke outside home	0.1	0.1	0.6	-0.5	-0.2	0.2	0.1	-0.1	-0.7	0.1	0.4	0.8	0.1	-0.3	0.5	0.1	-0.0	0.1	0.2	0.1	-0.4	-0.1
Alcohol intake frequency.	0.1	0.3	1.1	-0.2	0.4	0.3	-0.3	-0.3	-0.6	0.1	-0.6	0.7	-0.3	-0.5	0.1	-0.6	0.3	-1.0	-0.2	0.8	-0.1	-1.1
Ever had bowel cancer screening	0.1	0.1	0.5	-0.2	0.1	-0.2	-0.0	0.4	0.3	0.4	0.4	-0.4	0.1	0.4	-0.7	0.0	0.3	0.2	0.4	0.3	0.6	0.3
Diastolic blood pressure, automated reading	0.1	0.4	2.4	1.5	0.1	0.1	0.2	0.2	-1.1	-0.1	-1.1	1.2	-0.7	0.0	0.2	0.1	0.7	-0.3	0.6	0.5	0.2	-0.5
Myopia	0.1	0.1	0.5	-0.6	0.5	0.4	-0.7	-0.1	0.2	0.3	0.1	0.2	0.3	0.3	0.2	0.1	-0.5	-0.1	-0.4	-0.5	-0.6	-0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.4	2.4	0.2	0.3	0.5	-1.0	-1.1	0.1	0.3	0.6	-0.6	-0.2	-0.2	-0.3	0.3	-0.3	-0.4	-0.5	-1.6	-0.9	-0.2
Fluid intelligence score	0.0	0.1	0.3	0.5	0.1	-0.1	0.0	0.3	-0.6	-0.2	-0.3	-0.4	-0.5	-0.1	-0.3	-0.4	0.4	0.0	0.0	0.0	0.1	-0.1

Hub : Genes

ASCC3

Models

Trait associations