[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr6:124,741,508-127,355,237

Best TWAS P=1.29e-37 · Best GWAS P=4.74e-38 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CENPW	0.04	0.06	lasso	10	0.06	2.4e-07	12.760	-12.8	1.3e-37	-0.99	0.02	0.98	TRUE
9	GTEx	Thyroid	HEY2	0.22	0.24	lasso	6	0.23	1.0e-17	-8.891	-9.1	8.1e-20	-0.08	0.01	0.99	TRUE
5	GTEx	Heart Atrial Appendage	CENPW	0.17	0.01	enet	15	0.06	1.8e-03	12.733	-6.2	7.4e-10	-0.70	0.03	0.52	TRUE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	CENPW	0.04	0.06	blup	35	0.05	9.2e-07	12.620	-12.5	1.1e-35	-0.98	0.02	0.98	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CENPW	0.04	0.05	lasso	5	0.05	2.6e-06	12.775	-12.2	2.9e-34	-0.98	0.02	0.98	FALSE
13	METSIM	Adipose	NCOA7	0.05	0.05	enet	5	0.05	1.9e-07	7.125	9.2	5.1e-20	0.24	0.95	0.02	FALSE
2	CommonMind	Brain Pre-frontal Cortex	HEY2	0.15	0.20	lasso	10	0.21	6.7e-25	-8.949	-8.9	4.5e-19	-0.07	0.01	0.99	FALSE
8	GTEx	Testis	HEY2	0.31	0.17	lasso	5	0.19	7.4e-09	-8.891	-8.9	4.6e-19	-0.08	0.01	0.99	FALSE
11	METSIM	Adipose	CENPW	0.02	0.02	blup	189	0.01	8.3e-03	12.733	-8.2	1.6e-16	-0.74	0.02	0.74	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	HEY2	0.10	0.12	enet	15	0.13	9.8e-17	8.502	-8.2	3.0e-16	-0.06	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	HEY2	0.03	0.04	lasso	3	0.02	3.8e-03	7.924	-8.2	3.4e-16	-0.07	0.01	0.98	FALSE
4	GTEx	Esophagus Muscularis	HINT3	0.08	0.00	enet	14	0.00	2.9e-01	8.759	-7.2	5.2e-13	-0.11	0.07	0.04	FALSE
6	GTEx	Pancreas	HEY2	0.28	0.11	lasso	3	0.10	3.5e-05	-6.376	-7.2	5.7e-13	-0.06	0.10	0.90	FALSE
10	GTEx	Vagina	CENPW	0.24	-0.01	lasso	8	-0.01	7.9e-01	5.376	6.5	6.9e-11	0.40	0.04	0.07	FALSE
12	METSIM	Adipose	HEY2	0.02	0.04	lasso	1	0.02	1.6e-04	-6.407	-6.4	1.5e-10	-0.06	0.02	0.97	FALSE
18	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	HEY2	0.09	0.06	lasso	8	0.06	2.3e-03	-6.376	-6.4	1.5e-10	-0.04	0.03	0.75	FALSE
3	GTEx	Artery Coronary	TPD52L1	0.31	-0.01	enet	19	0.05	7.0e-03	0.056	-6.3	3.9e-10	-0.15	0.03	0.54	FALSE
7	GTEx	Skin Sun Exposed Lower leg	HINT3	0.08	0.01	lasso	4	0.03	2.0e-03	-4.609	-6.2	6.7e-10	-0.19	0.22	0.14	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HEY2	0.05	0.05	blup	36	0.05	4.9e-06	-6.376	-5.3	9.4e-08	-0.04	0.17	0.82	FALSE