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Traits
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Traits
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Arm fat-free mass (right)
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chr7:5,726,022-7,186,554
Best TWAS P=2.5e-08 · Best GWAS P=9.25e-09 conditioned to 0.044
5.8M
6M
6.2M
6.4M
6.6M
6.8M
7M
7.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
DAGLB
0.09
0.06
lasso
5
0.06
4.8e-08
5.6
-5.6
2.5e-08
-0.83
0.01
0.99
TRUE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
RAC1
0.03
0.02
enet
7
0.02
6.8e-05
4.4
5.5
3.9e-08
0.69
0.11
0.78
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
DAGLB
0.06
0.02
blup
71
0.03
7.4e-04
4.7
-5.3
8.7e-08
-0.70
0.01
0.77
FALSE
1
GTEx
Nerve Tibial
RAC1
0.19
0.07
enet
28
0.09
6.2e-07
4.7
5.2
2.1e-07
0.56
0.42
0.55
FALSE